PubMed

Smooth muscle LDL receptor-related protein-1 inactivation reduces vascular reactivity and promotes injury-induced neointima formation.

Basford JE, Moore ZW, Zhou L, Herz J, Hui DY.

Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1772-8. Epub 2009 Sep 3.PMID: 19729608 [PubMed - in process]Related articles

The phospholipase A(2) inhibitor methyl indoxam suppresses diet-induced obesity and glucose intolerance in mice.

Hui DY, Cope MJ, Labonté ED, Chang HT, Shao J, Goka E, Abousalham A, Charmot D, Buysse J.

Br J Pharmacol. 2009 Aug;157(7):1263-9. Epub 2009 Jun 25.PMID: 19563529 [PubMed - in process]Related articles

Morelloflavone blocks injury-induced neointimal formation by inhibiting vascular smooth muscle cell migration.

Pinkaew D, Cho SG, Hui DY, Wiktorowicz JE, Hutadilok-Towatana N, Mahabusarakam W, Tonganunt M, Stafford LJ, Phongdara A, Liu M, Fujise K.

Biochim Biophys Acta. 2009 Jan 1;1790(1):31-9. Epub 2008 Sep 30.PMID: 18930785 [PubMed - indexed for MEDLINE]Related articles

Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice.

Labonté ED, Camarota LM, Rojas JC, Jandacek RJ, Gilham DE, Davies JP, Ioannou YA, Tso P, Hui DY, Howles PN.

Am J Physiol Gastrointest Liver Physiol. 2008 Oct;295(4):G776-83. Epub 2008 Aug 21.PMID: 18718999 [PubMed - indexed for MEDLINE]Related articlesFree article

An analysis of the role of a retroendocytosis pathway in ABCA1-mediated cholesterol efflux from macrophages.

Faulkner LE, Panagotopulos SE, Johnson JD, Woollett LA, Hui DY, Witting SR, Maiorano JN, Davidson WS.

J Lipid Res. 2008 Jun;49(6):1322-32. Epub 2008 Mar 22.PMID: 18359958 [PubMed - indexed for MEDLINE]Related articlesFree article

Intimal hyperplasia in murine models.

Hui DY.

Curr Drug Targets. 2008 Mar;9(3):251-60. Review.PMID: 18336244 [PubMed - indexed for MEDLINE]Related articles

Development and physiological regulation of intestinal lipid absorption. III. Intestinal transporters and cholesterol absorption.

Hui DY, Labonté ED, Howles PN.

Am J Physiol Gastrointest Liver Physiol. 2008 Apr;294(4):G839-43. Epub 2008 Feb 14. Review.PMID: 18276831 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice.

Hofmann SM, Zhou L, Perez-Tilve D, Greer T, Grant E, Wancata L, Thomas A, Pfluger PT, Basford JE, Gilham D, Herz J, Tschöp MH, Hui DY.

J Clin Invest. 2007 Nov;117(11):3271-82.PMID: 17948131 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective lipid delivery modulates glucose tolerance and metabolic response to diet in apolipoprotein E-deficient mice.

Hofmann SM, Perez-Tilve D, Greer TM, Coburn BA, Grant E, Basford JE, Tschöp MH, Hui DY.

Diabetes. 2008 Jan;57(1):5-12. Epub 2007 Oct 3.PMID: 17914034 [PubMed - indexed for MEDLINE]Related articlesFree article

The central melanocortin system directly controls peripheral lipid metabolism.

Nogueiras R, Wiedmer P, Perez-Tilve D, Veyrat-Durebex C, Keogh JM, Sutton GM, Pfluger PT, Castaneda TR, Neschen S, Hofmann SM, Howles PN, Morgan DA, Benoit SC, Szanto I, Schrott B, Schürmann A, Joost HG, Hammond C, Hui DY, Woods SC, Rahmouni K, Butler AA, Farooqi IS, O'Rahilly S, Rohner-Jeanrenaud F, Tschöp MH.

J Clin Invest. 2007 Nov;117(11):3475-88.PMID: 17885689 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity-associated improvements in metabolic profile through expansion of adipose tissue.

Kim JY, van de Wall E, Laplante M, Azzara A, Trujillo ME, Hofmann SM, Schraw T, Durand JL, Li H, Li G, Jelicks LA, Mehler MF, Hui DY, Deshaies Y, Shulman GI, Schwartz GJ, Scherer PE.

J Clin Invest. 2007 Sep;117(9):2621-37.PMID: 17717599 [PubMed - indexed for MEDLINE]Related articlesFree article

A no-no for NonO and JNK in extracellular matrix homeostasis and vascular stability.

Hui DY.

Arterioscler Thromb Vasc Biol. 2007 Aug;27(8):1677-8. No abstract available. PMID: 17634520 [PubMed - indexed for MEDLINE]Related articlesFree article

Carboxyl ester lipase deficiency exacerbates dietary lipid absorption abnormalities and resistance to diet-induced obesity in pancreatic triglyceride lipase knockout mice.

Gilham D, Labonté ED, Rojas JC, Jandacek RJ, Howles PN, Hui DY.

J Biol Chem. 2007 Aug 24;282(34):24642-9. Epub 2007 Jun 29.PMID: 17604277 [PubMed - indexed for MEDLINE]Related articlesFree article

Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles.

Labonté ED, Howles PN, Granholm NA, Rojas JC, Davies JP, Ioannou YA, Hui DY.

Biochim Biophys Acta. 2007 Sep;1771(9):1132-9. Epub 2007 Mar 16.PMID: 17442616 [PubMed - indexed for MEDLINE]Related articlesFree article

Diet-induced leptin resistance: the heart of the matter.

Tschöp MH, Hui DY, Horvath TL.

Endocrinology. 2007 Mar;148(3):921-3. No abstract available. PMID: 17303671 [PubMed - indexed for MEDLINE]Related articlesFree article

The modern art of atherosclerosis: a picture of colorful plants, cholesterol, and inflammation.

Frolov A, Hui DY.

Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):450-2. No abstract available. PMID: 17301323 [PubMed - indexed for MEDLINE]Related articlesFree article

Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to tumor necrosis factor-alpha.

Ting HJ, Stice JP, Schaff UY, Hui DY, Rutledge JC, Knowlton AA, Passerini AG, Simon SI.

Circ Res. 2007 Feb 16;100(3):381-90. Epub 2007 Jan 18.PMID: 17234968 [PubMed - indexed for MEDLINE]Related articlesFree article

Group 1B phospholipase A2-mediated lysophospholipid absorption directly contributes to postprandial hyperglycemia.

Labonté ED, Kirby RJ, Schildmeyer NM, Cannon AM, Huggins KW, Hui DY.

Diabetes. 2006 Apr;55(4):935-41.PMID: 16567514 [PubMed - indexed for MEDLINE]Related articlesFree article

The biotin-capture lipid affinity assay: a rapid method for determining lipid binding parameters for apolipoproteins.

Davidson WS, Ghering AB, Beish L, Tubb MR, Hui DY, Pearson K.

J Lipid Res. 2006 Feb;47(2):440-9. Epub 2005 Nov 2.PMID: 16267343 [PubMed - indexed for MEDLINE]Related articlesFree article

Carboxyl ester lipase expression in macrophages increases cholesteryl ester accumulation and promotes atherosclerosis.

Kodvawala A, Ghering AB, Davidson WS, Hui DY.

J Biol Chem. 2005 Nov 18;280(46):38592-8. Epub 2005 Sep 14.PMID: 16166077 [PubMed - indexed for MEDLINE]Related articlesFree article

Apolipoprotein E inhibition of vascular hyperplasia and neointima formation requires inducible nitric oxide synthase.

Moore ZW, Hui DY.

J Lipid Res. 2005 Oct;46(10):2083-90. Epub 2005 Aug 1.PMID: 16061951 [PubMed - indexed for MEDLINE]Related articlesFree article

The receptor binding domain of apolipoprotein E is responsible for its antioxidant activity.

Pham T, Kodvawala A, Hui DY.

Biochemistry. 2005 May 24;44(20):7577-82.PMID: 15896001 [PubMed - indexed for MEDLINE]Related articles

Molecular mechanisms of cholesterol absorption and transport in the intestine.

Hui DY, Howles PN.

Semin Cell Dev Biol. 2005 Apr;16(2):183-92. Review.PMID: 15797829 [PubMed - indexed for MEDLINE]Related articles

Distinct signaling mechanisms for apoE inhibition of cell migration and proliferation.

Hui DY, Basford JE.

Neurobiol Aging. 2005 Mar;26(3):317-23. Review.PMID: 15639309 [PubMed - indexed for MEDLINE]Related articles

Apolipoprotein E-induced cell signaling in the vessel wall.

Hui DY.

Rev Endocr Metab Disord. 2004 Dec;5(4):335-41. Review. No abstract available. PMID: 15486466 [PubMed - indexed for MEDLINE]Related articles

Vascular apolipoprotein e expression and recruitment from circulation to modulate smooth muscle cell response to endothelial denudation.

Moore ZW, Zhu B, Kuhel DG, Hui DY.

Am J Pathol. 2004 Jun;164(6):2109-16.PMID: 15161645 [PubMed - indexed for MEDLINE]Related articlesFree article

Carboxyl ester lipase cofractionates with scavenger receptor BI in hepatocyte lipid rafts and enhances selective uptake and hydrolysis of cholesteryl esters from HDL3.

Camarota LM, Chapman JM, Hui DY, Howles PN.

J Biol Chem. 2004 Jun 25;279(26):27599-606. Epub 2004 Apr 21.PMID: 15105424 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipoprotein receptors in the vascular wall.

Herz J, Hui DY.

Curr Opin Lipidol. 2004 Apr;15(2):175-81. Review.PMID: 15017360 [PubMed - indexed for MEDLINE]Related articles

Rate of gastric emptying influences dietary cholesterol absorption efficiency in selected inbred strains of mice.

Kirby RJ, Howles PN, Hui DY.

J Lipid Res. 2004 Jan;45(1):89-98. Epub 2003 Oct 16.PMID: 14563823 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic triglyceride lipase deficiency minimally affects dietary fat absorption but dramatically decreases dietary cholesterol absorption in mice.

Huggins KW, Camarota LM, Howles PN, Hui DY.

J Biol Chem. 2003 Oct 31;278(44):42899-905. Epub 2003 Aug 12.PMID: 12915407 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin replacement therapy but not dietary polyunsaturated fatty acid alleviates HIV protease inhibitor-induced dyslipidemia and lipodystrophy in mice.

Riddle TM, Fichtenbaum CJ, Hui DY.

J Acquir Immune Defic Syndr. 2003 Aug 15;33(5):564-70.PMID: 12902799 [PubMed - indexed for MEDLINE]Related articles

Apolipoprotein E binding to low density lipoprotein receptor-related protein-1 inhibits cell migration via activation of cAMP-dependent protein kinase A.

Zhu Y, Hui DY.

J Biol Chem. 2003 Sep 19;278(38):36257-63. Epub 2003 Jul 11.PMID: 12857755 [PubMed - indexed for MEDLINE]Related articlesFree article

HIV protease inhibitors and atherosclerosis.

Hui DY.

J Clin Invest. 2003 Feb;111(3):317-8. Review. No abstract available. PMID: 12569155 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of HIV protease inhibitor therapy on lipid metabolism.

Hui DY.

Prog Lipid Res. 2003 Mar;42(2):81-92. Review.PMID: 12547652 [PubMed - indexed for MEDLINE]Related articles

Carboxyl ester lipase: structure-function relationship and physiological role in lipoprotein metabolism and atherosclerosis.

Hui DY, Howles PN.

J Lipid Res. 2002 Dec;43(12):2017-30. Review.PMID: 12454261 [PubMed - indexed for MEDLINE]Related articlesFree article

Protection against diet-induced obesity and obesity- related insulin resistance in Group 1B PLA2-deficient mice.

Huggins KW, Boileau AC, Hui DY.

Am J Physiol Endocrinol Metab. 2002 Nov;283(5):E994-E1001.PMID: 12376327 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct apolipoprotein E isoform preference for inhibition of smooth muscle cell migration and proliferation.

Zeleny M, Swertfeger DK, Weisgraber KH, Hui DY.

Biochemistry. 2002 Oct 1;41(39):11820-3.PMID: 12269825 [PubMed - indexed for MEDLINE]Related articles

The HIV protease inhibitor ritonavir increases lipoprotein production and has no effect on lipoprotein clearance in mice.

Riddle TM, Schildmeyer NM, Phan C, Fichtenbaum CJ, Hui DY.

J Lipid Res. 2002 Sep;43(9):1458-63.PMID: 12235177 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of apolipoprotein A-I helix 10 in apolipoprotein-mediated cholesterol efflux via the ATP-binding cassette transporter ABCA1.

Panagotopulos SE, Witting SR, Horace EM, Hui DY, Maiorano JN, Davidson WS.

J Biol Chem. 2002 Oct 18;277(42):39477-84. Epub 2002 Aug 13.PMID: 12181325 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinction in genetic determinants for injury-induced neointimal hyperplasia and diet-induced atherosclerosis in inbred mice.

Kuhel DG, Zhu B, Witte DP, Hui DY.

Arterioscler Thromb Vasc Biol. 2002 Jun 1;22(6):955-60.PMID: 12067904 [PubMed - indexed for MEDLINE]Related articlesFree article

Separation of micelles and vesicles within lumenal aspirates from healthy humans: solubilization of cholesterol after a meal.

Yao L, Heubi JE, Buckley DD, Fierra H, Setchell KD, Granholm NA, Tso P, Hui DY, Woollett LA.

J Lipid Res. 2002 Apr;43(4):654-60.PMID: 11907149 [PubMed - indexed for MEDLINE]Related articlesFree article

Both apolipoprotein E and immune deficiency exacerbate neointimal hyperplasia after vascular injury in mice.

Zhu B, Reardon CA, Getz GS, Hui DY.

Arterioscler Thromb Vasc Biol. 2002 Mar 1;22(3):450-5.PMID: 11884289 [PubMed - indexed for MEDLINE]Related articlesFree article

Bile salt-stimulated carboxyl ester lipase influences lipoprotein assembly and secretion in intestine: a process mediated via ceramide hydrolysis.

Kirby RJ, Zheng S, Tso P, Howles PN, Hui DY.

J Biol Chem. 2002 Feb 8;277(6):4104-9. Epub 2001 Dec 3.PMID: 11733511 [PubMed - indexed for MEDLINE]Related articlesFree article

Low density lipoprotein receptor-related protein mediates apolipoprotein E inhibition of smooth muscle cell migration.

Swertfeger DK, Bu G, Hui DY.

J Biol Chem. 2002 Feb 8;277(6):4141-6. Epub 2001 Dec 5.PMID: 11739389 [PubMed - indexed for MEDLINE]Related articlesFree article

HIV protease inhibitor induces fatty acid and sterol biosynthesis in liver and adipose tissues due to the accumulation of activated sterol regulatory element-binding proteins in the nucleus.

Riddle TM, Kuhel DG, Woollett LA, Fichtenbaum CJ, Hui DY.

J Biol Chem. 2001 Oct 5;276(40):37514-9. Epub 2001 Aug 23.PMID: 11546771 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted overexpression of IGF-I in smooth muscle cells of transgenic mice enhances neointimal formation through increased proliferation and cell migration after intraarterial injury.

Zhu B, Zhao G, Witte DP, Hui DY, Fagin JA.

Endocrinology. 2001 Aug;142(8):3598-606.PMID: 11459808 [PubMed - indexed for MEDLINE]Related articlesFree article

Differentiation-dependent expression and localization of the class B type I scavenger receptor in intestine.

Cai SF, Kirby RJ, Howles PN, Hui DY.

J Lipid Res. 2001 Jun;42(6):902-9.PMID: 11369797 [PubMed - indexed for MEDLINE]Related articlesFree article

Apolipoprotein E receptor binding versus heparan sulfate proteoglycan binding in its regulation of smooth muscle cell migration and proliferation.

Swertfeger DK, Hui DY.

J Biol Chem. 2001 Jul 6;276(27):25043-8. Epub 2001 May 11.PMID: 11350966 [PubMed - indexed for MEDLINE]Related articles

Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span.

Du H, Heur M, Duanmu M, Grabowski GA, Hui DY, Witte DP, Mishra J.

J Lipid Res. 2001 Apr;42(4):489-500.PMID: 11290820 [PubMed - indexed for MEDLINE]Related articlesFree article

Compensatory phospholipid digestion is required for cholesterol absorption in pancreatic phospholipase A(2)-deficient mice.

Richmond BL, Boileau AC, Zheng S, Huggins KW, Granholm NA, Tso P, Hui DY.

Gastroenterology. 2001 Apr;120(5):1193-202.PMID: 11266383 [PubMed - indexed for MEDLINE]Related articles