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    Results: 1 to 50 of 99

    1.

    Patterns of Asymmetry in Primary Tooth Emergence of Australian Twins.

    Mihailidis S, Woodroffe SN, Hughes TE, Bockmann MR, Townsend GC.

    Front Oral Biol. 2009;13:110-115. Epub 2009 Sep 21.PMID: 19828980 [PubMed - as supplied by publisher]Related articles

    2.

    Color hues in red fluorescent proteins are due to internal quadratic Stark effect.

    Drobizhev M, Tillo S, Makarov NS, Hughes TE, Rebane A.

    J Phys Chem B. 2009 Oct 1;113(39):12860-4.PMID: 19775174 [PubMed - in process]Related articles

    3.

    Metabolic implications of dietary trans-fatty acids.

    Dorfman SE, Laurent D, Gounarides JS, Li X, Mullarkey TL, Rocheford EC, Sari-Sarraf F, Hirsch EA, Hughes TE, Commerford SR.

    Obesity (Silver Spring). 2009 Jun;17(6):1200-7. Epub 2009 Feb 19. Erratum in: Obesity (Silver Spring). 2009 Jul;17(7):1474. PMID: 19584878 [PubMed - indexed for MEDLINE]Related articles

    4.

    Emerging therapies for metabolic diseases--the focus is on diabetes and obesity.

    Hughes TE.

    Curr Opin Chem Biol. 2009 Jun;13(3):332-7. Epub 2009 May 23. Review.PMID: 19482541 [PubMed - indexed for MEDLINE]Related articles

    5.

    The effect of casein phosphopeptide-amorphous calcium phosphate on erosive dentine wear.

    Ranjitkar S, Narayana T, Kaidonis JA, Hughes TE, Richards LC, Townsend GC.

    Aust Dent J. 2009 Jun;54(2):101-7.PMID: 19473150 [PubMed - indexed for MEDLINE]Related articles

    6.

    Absolute two-photon absorption spectra and two-photon brightness of orange and red fluorescent proteins.

    Drobizhev M, Tillo S, Makarov NS, Hughes TE, Rebane A.

    J Phys Chem B. 2009 Jan 29;113(4):855-9.PMID: 19127988 [PubMed - indexed for MEDLINE]Related articles

    7.

    Variants in MTNR1B influence fasting glucose levels.

    Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M, Lyssenko V, Chen WM, Ahmadi K, Beckmann JS, Bergman RN, Bochud M, Bonnycastle LL, Buchanan TA, Cao A, Cervino A, Coin L, Collins FS, Crisponi L, de Geus EJ, Dehghan A, Deloukas P, Doney AS, Elliott P, Freimer N, Gateva V, Herder C, Hofman A, Hughes TE, Hunt S, Illig T, Inouye M, Isomaa B, Johnson T, Kong A, Krestyaninova M, Kuusisto J, Laakso M, Lim N, Lindblad U, Lindgren CM, McCann OT, Mohlke KL, Morris AD, Naitza S, Orrù M, Palmer CN, Pouta A, Randall J, Rathmann W, Saramies J, Scheet P, Scott LJ, Scuteri A, Sharp S, Sijbrands E, Smit JH, Song K, Steinthorsdottir V, Stringham HM, Tuomi T, Tuomilehto J, Uitterlinden AG, Voight BF, Waterworth D, Wichmann HE, Willemsen G, Witteman JC, Yuan X, Zhao JH, Zeggini E, Schlessinger D, Sandhu M, Boomsma DI, Uda M, Spector TD, Penninx BW, Altshuler D, Vollenweider P, Jarvelin MR, Lakatta E, Waeber G, Fox CS, Peltonen L, Groop LC, Mooser V, Cupples LA, Thorsteinsdottir U, Boehnke M, Barroso I, Van Duijn C, Dupuis J, Watanabe RM, Stefansson K, McCarthy MI, Wareham NJ, Meigs JB, Abecasis GR.

    Nat Genet. 2009 Jan;41(1):77-81. Epub 2008 Dec 7.PMID: 19060907 [PubMed - indexed for MEDLINE]Related articles

    8.

    Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations.

    Orho-Melander M, Melander O, Guiducci C, Perez-Martinez P, Corella D, Roos C, Tewhey R, Rieder MJ, Hall J, Abecasis G, Tai ES, Welch C, Arnett DK, Lyssenko V, Lindholm E, Saxena R, de Bakker PI, Burtt N, Voight BF, Hirschhorn JN, Tucker KL, Hedner T, Tuomi T, Isomaa B, Eriksson KF, Taskinen MR, Wahlstrand B, Hughes TE, Parnell LD, Lai CQ, Berglund G, Peltonen L, Vartiainen E, Jousilahti P, Havulinna AS, Salomaa V, Nilsson P, Groop L, Altshuler D, Ordovas JM, Kathiresan S.

    Diabetes. 2008 Nov;57(11):3112-21. Epub 2008 Aug 4.PMID: 18678614 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    FRET with multiply labeled HERG K(+) channels as a reporter of the in vivo coarse architecture of the cytoplasmic domains.

    Miranda P, Manso DG, Barros F, Carretero L, Hughes TE, Alonso-Ron C, Domínguez P, de la Peña P.

    Biochim Biophys Acta. 2008 Oct;1783(10):1681-99. Epub 2008 Jun 19.PMID: 18634834 [PubMed - indexed for MEDLINE]Related articles

    10.

    Use of atypical antipsychotic drugs for schizophrenia in Maine Medicaid following a policy change.

    Soumerai SB, Zhang F, Ross-Degnan D, Ball DE, LeCates RF, Law MR, Hughes TE, Chapman D, Adams AS.

    Health Aff (Millwood). 2008 May-Jun;27(3):w185-95. Epub 2008 Apr 1.PMID: 18381404 [PubMed - indexed for MEDLINE]Related articles

    11.

    Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.

    Zeggini E, Scott LJ, Saxena R, Voight BF, Marchini JL, Hu T, de Bakker PI, Abecasis GR, Almgren P, Andersen G, Ardlie K, Boström KB, Bergman RN, Bonnycastle LL, Borch-Johnsen K, Burtt NP, Chen H, Chines PS, Daly MJ, Deodhar P, Ding CJ, Doney AS, Duren WL, Elliott KS, Erdos MR, Frayling TM, Freathy RM, Gianniny L, Grallert H, Grarup N, Groves CJ, Guiducci C, Hansen T, Herder C, Hitman GA, Hughes TE, Isomaa B, Jackson AU, Jørgensen T, Kong A, Kubalanza K, Kuruvilla FG, Kuusisto J, Langenberg C, Lango H, Lauritzen T, Li Y, Lindgren CM, Lyssenko V, Marvelle AF, Meisinger C, Midthjell K, Mohlke KL, Morken MA, Morris AD, Narisu N, Nilsson P, Owen KR, Palmer CN, Payne F, Perry JR, Pettersen E, Platou C, Prokopenko I, Qi L, Qin L, Rayner NW, Rees M, Roix JJ, Sandbaek A, Shields B, Sjögren M, Steinthorsdottir V, Stringham HM, Swift AJ, Thorleifsson G, Thorsteinsdottir U, Timpson NJ, Tuomi T, Tuomilehto J, Walker M, Watanabe RM, Weedon MN, Willer CJ; Wellcome Trust Case Control Consortium, Illig T, Hveem K, Hu FB, Laakso M, Stefansson K, Pedersen O, Wareham NJ, Barroso I, Hattersley AT, Collins FS, Groop L, McCarthy MI, Boehnke M, Altshuler D.

    Nat Genet. 2008 May;40(5):638-45. Epub 2008 Mar 30.PMID: 18372903 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Strong genetic control of emergence of human primary incisors.

    Hughes TE, Bockmann MR, Seow K, Gotjamanos T, Gully N, Richards LC, Townsend GC.

    J Dent Res. 2007 Dec;86(12):1160-5.PMID: 18037648 [PubMed - indexed for MEDLINE]Related articles

    13.
    14.

    Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.

    Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research, Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, Chen H, Roix JJ, Kathiresan S, Hirschhorn JN, Daly MJ, Hughes TE, Groop L, Altshuler D, Almgren P, Florez JC, Meyer J, Ardlie K, Bengtsson Boström K, Isomaa B, Lettre G, Lindblad U, Lyon HN, Melander O, Newton-Cheh C, Nilsson P, Orho-Melander M, Råstam L, Speliotes EK, Taskinen MR, Tuomi T, Guiducci C, Berglund A, Carlson J, Gianniny L, Hackett R, Hall L, Holmkvist J, Laurila E, Sjögren M, Sterner M, Surti A, Svensson M, Svensson M, Tewhey R, Blumenstiel B, Parkin M, Defelice M, Barry R, Brodeur W, Camarata J, Chia N, Fava M, Gibbons J, Handsaker B, Healy C, Nguyen K, Gates C, Sougnez C, Gage D, Nizzari M, Gabriel SB, Chirn GW, Ma Q, Parikh H, Richardson D, Ricke D, Purcell S.

    Science. 2007 Jun 1;316(5829):1331-6. Epub 2007 Apr 26.PMID: 17463246 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Regions of alpha-amino-5-methyl-3-hydroxy-4-isoxazole propionic acid receptor subunits that are permissive for the insertion of green fluorescent protein.

    Sheridan DL, Robert A, Cho CH, Howe JR, Hughes TE.

    Neuroscience. 2006 Aug 25;141(2):837-49. Epub 2006 Jun 12.PMID: 16765522 [PubMed - indexed for MEDLINE]Related articles

    16.

    Ringing the dinner bell for insulin: muscarinic M3 receptor activity in the control of pancreatic beta cell function.

    Gromada J, Hughes TE.

    Cell Metab. 2006 Jun;3(6):390-2. Review.PMID: 16753574 [PubMed - indexed for MEDLINE]Related articles

    17.

    Chorion type, birthweight discordance and tooth-size variability in Australian monozygotic twins.

    Race JP, Townsend GC, Hughes TE.

    Twin Res Hum Genet. 2006 Apr;9(2):285-91.PMID: 16611500 [PubMed - indexed for MEDLINE]Related articles

    18.

    Generation of functional fluorescent BK channels by random insertion of GFP variants.

    Giraldez T, Hughes TE, Sigworth FJ.

    J Gen Physiol. 2005 Nov;126(5):429-38.PMID: 16260837 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Beta-cell expression of a dominant-negative HNF-1alpha compromises the ability of inhibition of dipeptidyl peptidase-4 to elicit a long-term augmentation of insulin secretion in mice.

    Ahrén B, Sörhede Winzell M, Burkey B, Hughes TE.

    Eur J Pharmacol. 2005 Oct 3;521(1-3):164-8. Epub 2005 Sep 19.PMID: 16171801 [PubMed - indexed for MEDLINE]Related articles

    20.

    Acute and chronic effects of the incretin enhancer vildagliptin in insulin-resistant rats.

    Burkey BF, Li X, Bolognese L, Balkan B, Mone M, Russell M, Hughes TE, Wang PR.

    J Pharmacol Exp Ther. 2005 Nov;315(2):688-95. Epub 2005 Jul 18.PMID: 16027230 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    The effect of birthweight on tooth-size variability in twins.

    Apps MV, Hughes TE, Townsend GC.

    Twin Res. 2004 Oct;7(5):415-20.PMID: 15527656 [PubMed - indexed for MEDLINE]Related articles

    24.

    Binding of receptor for advanced glycation end products (RAGE) ligands is not sufficient to induce inflammatory signals: lack of activity of endotoxin-free albumin-derived advanced glycation end products.

    Valencia JV, Mone M, Koehne C, Rediske J, Hughes TE.

    Diabetologia. 2004 May;47(5):844-52. Epub 2004 May 1.PMID: 15127201 [PubMed - indexed for MEDLINE]Related articles

    25.

    Divergent pathways of gene expression are activated by the RAGE ligands S100b and AGE-BSA.

    Valencia JV, Mone M, Zhang J, Weetall M, Buxton FP, Hughes TE.

    Diabetes. 2004 Mar;53(3):743-51.PMID: 14988260 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    Advanced glycation end product ligands for the receptor for advanced glycation end products: biochemical characterization and formation kinetics.

    Valencia JV, Weldon SC, Quinn D, Kiers GH, DeGroot J, TeKoppele JM, Hughes TE.

    Anal Biochem. 2004 Jan 1;324(1):68-78.PMID: 14654047 [PubMed - indexed for MEDLINE]Related articles

    27.

    Physician perceptions of the use of medications for attention deficit hyperactivity disorder.

    Stockl KM, Hughes TE, Jarrar MA, Secnik K, Perwien AR.

    J Manag Care Pharm. 2003 Sep-Oct;9(5):416-23.PMID: 14613439 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    Cellular localization of GFP-tagged alpha subunits.

    Hynes TR, Hughes TE, Berlot CH.

    Methods Mol Biol. 2004;237:233-46. Review.PMID: 14501054 [PubMed - indexed for MEDLINE]Related articles

    29.

    1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties.

    Villhauer EB, Brinkman JA, Naderi GB, Burkey BF, Dunning BE, Prasad K, Mangold BL, Russell ME, Hughes TE.

    J Med Chem. 2003 Jun 19;46(13):2774-89.PMID: 12801240 [PubMed - indexed for MEDLINE]Related articles

    30.

    Dental characteristics of patients with Duchenne muscular dystrophy.

    Symons AL, Townsend GC, Hughes TE.

    ASDC J Dent Child. 2002 Sep-Dec;69(3):277-83, 234.PMID: 12613312 [PubMed - indexed for MEDLINE]Related articles

    31.

    The expression of dominant-negative subunits selectively suppresses neuronal AMPA and kainate receptors.

    Robert A, Hyde R, Hughes TE, Howe JR.

    Neuroscience. 2002;115(4):1199-210.PMID: 12453491 [PubMed - indexed for MEDLINE]Related articles

    32.

    A new way to rapidly create functional, fluorescent fusion proteins: random insertion of GFP with an in vitro transposition reaction.

    Sheridan DL, Berlot CH, Robert A, Inglis FM, Jakobsdottir KB, Howe JR, Hughes TE.

    BMC Neurosci. 2002 Jun 19;3:7.PMID: 12086589 [PubMed - indexed for MEDLINE]Related articlesFree article

    33.

    Polymerase chain reaction based detection of fungi in infected corneas.

    Gaudio PA, Gopinathan U, Sangwan V, Hughes TE.

    Br J Ophthalmol. 2002 Jul;86(7):755-60.PMID: 12084744 [PubMed - indexed for MEDLINE]Related articlesFree article

    35.

    1-[2-[(5-Cyanopyridin-2-yl)amino]ethylamino]acetyl-2-(S)-pyrrolidinecarbonitrile: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties.

    Villhauer EB, Brinkman JA, Naderi GB, Dunning BE, Mangold BL, Mone MD, Russell ME, Weldon SC, Hughes TE.

    J Med Chem. 2002 Jun 6;45(12):2362-5.PMID: 12036346 [PubMed - indexed for MEDLINE]Related articles

    36.

    Preservation of active incretin hormones by inhibition of dipeptidyl peptidase IV suppresses meal-induced incretin secretion in dogs.

    Deacon CF, Wamberg S, Bie P, Hughes TE, Holst JJ.

    J Endocrinol. 2002 Feb;172(2):355-62.PMID: 11834453 [PubMed - indexed for MEDLINE]Related articlesFree article

    37.

    Transgenic expression of the jellyfish green fluorescent protein in the cone photoreceptors of the mouse.

    Fei Y, Hughes TE.

    Vis Neurosci. 2001 Jul-Aug;18(4):615-23.PMID: 11829307 [PubMed - indexed for MEDLINE]Related articles

    38.

    Cre stoplight: a red/green fluorescent reporter of Cre recombinase expression in living cells.

    Yang YS, Hughes TE.

    Biotechniques. 2001 Nov;31(5):1036, 1038, 1040-1.PMID: 11730010 [PubMed - indexed for MEDLINE]Related articles

    39.

    Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients.

    Toft-Nielsen MB, Damholt MB, Madsbad S, Hilsted LM, Hughes TE, Michelsen BK, Holst JJ.

    J Clin Endocrinol Metab. 2001 Aug;86(8):3717-23.PMID: 11502801 [PubMed - indexed for MEDLINE]Related articlesFree article

    40.

    Subunit interactions and AMPA receptor desensitization.

    Robert A, Irizarry SN, Hughes TE, Howe JR.

    J Neurosci. 2001 Aug 1;21(15):5574-86.PMID: 11466429 [PubMed - indexed for MEDLINE]Related articlesFree article

    42.

    Nuclear trafficking of photoreceptor protein crx: the targeting sequence and pathologic implications.

    Fei Y, Hughes TE.

    Invest Ophthalmol Vis Sci. 2000 Sep;41(10):2849-56.PMID: 10967037 [PubMed - indexed for MEDLINE]Related articlesFree article

    43.

    Minimizing excessive composite resin when fabricating fiber-reinforced splints.

    Hughes TE, Strassler HE.

    J Am Dent Assoc. 2000 Jul;131(7):977-9. No abstract available. PMID: 10916335 [PubMed - indexed for MEDLINE]Related articlesFree article

    44.

    1-Aminomethylisoquinoline-4-carboxylates as novel dipeptidylpeptidase IV inhibitors.

    Coppola GM, Zhang YL, Schuster HF, Russell ME, Hughes TE.

    Bioorg Med Chem Lett. 2000 Jul 17;10(14):1555-8.PMID: 10915049 [PubMed - indexed for MEDLINE]Related articles

    45.

    NVP-DPP728 (1-[[[2-[(5-cyanopyridin-2-yl)amino]ethyl]amino]acetyl]-2-cyano-(S)- pyrrolidine), a slow-binding inhibitor of dipeptidyl peptidase IV.

    Hughes TE, Mone MD, Russell ME, Weldon SC, Villhauer EB.

    Biochemistry. 1999 Sep 7;38(36):11597-603.PMID: 10512614 [PubMed - indexed for MEDLINE]Related articles

    46.

    Trafficking of endothelial nitric-oxide synthase in living cells. Quantitative evidence supporting the role of palmitoylation as a kinetic trapping mechanism limiting membrane diffusion.

    Sowa G, Liu J, Papapetropoulos A, Rex-Haffner M, Hughes TE, Sessa WC.

    J Biol Chem. 1999 Aug 6;274(32):22524-31.PMID: 10428829 [PubMed - indexed for MEDLINE]Related articlesFree article

    47.

    Identification of olfactory receptor mRNA sequences from the rat olfactory bulb glomerular layer.

    Singer MS, Hughes TE, Shepherd GM, Greer CA.

    Neuroreport. 1998 Nov 16;9(16):3745-8.PMID: 9858390 [PubMed - indexed for MEDLINE]Related articles

    48.

    Ionotropic glutamate receptors in the retina: moving from molecules to circuits.

    Lo W, Molloy R, Hughes TE.

    Vision Res. 1998 May;38(10):1399-410.PMID: 9667007 [PubMed - indexed for MEDLINE]Related articles

    49.

    Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.

    Deacon CF, Hughes TE, Holst JJ.

    Diabetes. 1998 May;47(5):764-9.PMID: 9588448 [PubMed - indexed for MEDLINE]Related articlesFree article

    50.

    Sec3p is a spatial landmark for polarized secretion in budding yeast.

    Finger FP, Hughes TE, Novick P.

    Cell. 1998 Feb 20;92(4):559-71.PMID: 9491896 [PubMed - indexed for MEDLINE]Related articles

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