PubMed

A Meta-Analysis of the Mechanism of Blood Pressure Change With Aging.

Baksi AJ, Treibel TA, Davies JE, Hadjiloizou N, Foale RA, Parker KH, Francis DP, Mayet J, Hughes AD.

J Am Coll Cardiol. 2009 Nov 24;54(22):2087-2092.PMID: 19926018 [PubMed - as supplied by publisher]Related articles

Identification of immune parameters to differentiate disease states among sheep infected with Mycobacterium avium subsp paratuberculosis.

Gillan S, O'Brien R, Hughes AD, Griffin JF.

Clin Vaccine Immunol. 2009 Nov 18. [Epub ahead of print]PMID: 19923568 [PubMed - as supplied by publisher]Related articles

NS11021, a novel opener of large-conductance Ca(2+)-activated K(+) channels, enhances erectile responses in rats.

Kun A, Matchkov VV, Stankevicius E, Nardi A, Hughes AD, Kirkeby HJ, Demnitz J, Simonsen U.

Br J Pharmacol. 2009 Nov;158(6):1465-76. Epub 2009 Oct 20.PMID: 19845682 [PubMed - in process]Related articles

Atorvastatin treatment is associated with less augmentation of the carotid pressure waveform in hypertension: a substudy of the Anglo-Scandinavian Cardiac Outcome Trial (ASCOT).

Manisty C, Mayet J, Tapp RJ, Sever PS, Poulter N, McG Thom SA, Hughes AD; ASCOT Investigators.

Hypertension. 2009 Nov;54(5):1009-13. Epub 2009 Aug 31.PMID: 19720956 [PubMed - indexed for MEDLINE]Related articles

Differences in the magnitude of wave reflection account for differential effects of amlodipine- versus atenolol-based regimens on central blood pressure: an Anglo-Scandinavian Cardiac Outcome Trial substudy.

Manisty CH, Zambanini A, Parker KH, Davies JE, Francis DP, Mayet J, McG Thom SA, Hughes AD; Anglo-Scandinavian Cardiac Outcome Trial Investigators.

Hypertension. 2009 Oct;54(4):724-30. Epub 2009 Aug 24.PMID: 19704107 [PubMed - indexed for MEDLINE]Related articles

Retinal arterioles have impaired reactivity to hyperoxia in type 1 diabetes.

Justesen BL, Mistry P, Chaturvedi N, Thom SA, Witt N, Köhler D, Hughes AD, Sjølie AK.

Acta Ophthalmol. 2009 Jul 21. [Epub ahead of print]PMID: 19681793 [PubMed - as supplied by publisher]Related articles

Effects of blood pressure lowering and intensive glucose control on the incidence and progression of retinopathy in patients with type 2 diabetes mellitus: a randomised controlled trial.

Beulens JW, Patel A, Vingerling JR, Cruickshank JK, Hughes AD, Stanton A, Lu J, McG Thom SA, Grobbee DE, Stolk RP; AdRem project team; ADVANCE management committee.

Diabetologia. 2009 Oct;52(10):2027-36. Epub 2009 Jul 25.PMID: 19633827 [PubMed - in process]Related articles

Dynamic CO2 therapy in periodic breathing: a modeling study to determine optimal timing and dosage regimes.

Mebrate Y, Willson K, Manisty CH, Baruah R, Mayet J, Hughes AD, Parker KH, Francis DP.

J Appl Physiol. 2009 Sep;107(3):696-706. Epub 2009 Jul 23.PMID: 19628721 [PubMed - indexed for MEDLINE]Related articles

Calcium channel regulation in vascular smooth muscle cells: Synergistic effects of statins and calcium channel blockers.

Clunn GF, Sever PS, Hughes AD.

Int J Cardiol. 2009 Jun 10. [Epub ahead of print]PMID: 19523699 [PubMed - as supplied by publisher]Related articles

Serum amyloid A, C-reactive protein, and retinal microvascular changes in hypertensive diabetic and nondiabetic individuals: an Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) substudy.

Stettler C, Witt N, Tapp RJ, Thom S, Allemann S, Tillin T, Stanton A, O'Brien E, Poulter N, Gallimore JR, Hughes AD, Chaturvedi N.

Diabetes Care. 2009 Jun;32(6):1098-100. Epub 2009 Feb 24.PMID: 19244088 [PubMed - indexed for MEDLINE]Related articlesFree article

Normal asynchrony of left ventricular long and short axes: Their relationship with aortic hemodynamics.

Page CM, Khir AW, Hughes AD, Chung R, Henein MY.

Int J Cardiol. 2009 Feb 20. [Epub ahead of print]PMID: 19230991 [PubMed - as supplied by publisher]Related articles

Determinants of retinal microvascular architecture in normal subjects.

Hughes AD, Wong TY, Witt N, Evans R, Thom SA, Klein BE, Chaturvedi N, Klein R.

Microcirculation. 2009 Feb;16(2):159-66.PMID: 19206002 [PubMed - indexed for MEDLINE]Related articles

Forward and backward waves in the arterial system: impedance or wave intensity analysis?

Hughes AD, Parker KH.

Med Biol Eng Comput. 2009 Feb;47(2):207-10. Epub 2009 Feb 6.PMID: 19198913 [PubMed - indexed for MEDLINE]Related articles

Wave intensity analysis and the development of the reservoir-wave approach.

Tyberg JV, Davies JE, Wang Z, Whitelaw WA, Flewitt JA, Shrive NG, Francis DP, Hughes AD, Parker KH, Wang JJ.

Med Biol Eng Comput. 2009 Feb;47(2):221-32. Epub 2009 Feb 3. Review.PMID: 19189147 [PubMed - indexed for MEDLINE]Related articles

Comparison of the retinal microvasculature in European and African-Caribbean people with diabetes.

Mahal S, Strain WD, Martinez-Perez ME, Thom SA, Chaturvedi N, Hughes AD.

Clin Sci (Lond). 2009 Aug 14;117(6):229-36.PMID: 19173676 [PubMed - indexed for MEDLINE]Related articles

Pharmacological properties of TD-6301, a novel bladder selective muscarinic receptor antagonist.

McNamara A, Pulido-Rios MT, Sweazey S, Obedencio GP, Thibodeaux H, Renner T, Armstrong SR, Steinfeld T, Hughes AD, Wilson RD, Jasper JR, Mammen M, Hegde SS.

Eur J Pharmacol. 2009 Mar 1;605(1-3):145-52. Epub 2009 Jan 10.PMID: 19168050 [PubMed - indexed for MEDLINE]Related articles

Reservoir-wave separation and wave intensity analysis applied to carotid arteries: a hybrid 1D model to understand haemodynamics.

Aguado-Sierra J, Davies JE, Hadjiloizou N, Francis D, Mayet J, Hughes AD, Parker KH.

Conf Proc IEEE Eng Med Biol Soc. 2008;2008:1381-4.PMID: 19162925 [PubMed - indexed for MEDLINE]Related articles

Stress phase angle depicts differences in coronary artery hemodynamics due to changes in flow and geometry after percutaneous coronary intervention.

Torii R, Wood NB, Hadjiloizou N, Dowsey AW, Wright AR, Hughes AD, Davies J, Francis DP, Mayet J, Yang GZ, Thom SA, Xu XY.

Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H765-76. Epub 2009 Jan 16.PMID: 19151251 [PubMed - indexed for MEDLINE]Related articles

Impact of statin therapy on central aortic pressures and hemodynamics: principal results of the Conduit Artery Function Evaluation-Lipid-Lowering Arm (CAFE-LLA) Study.

Williams B, Lacy PS, Cruickshank JK, Collier D, Hughes AD, Stanton A, Thom S, Thurston H; CAFE and ASCOT Investigators.

Circulation. 2009 Jan 6;119(1):53-61. Epub 2008 Dec 22.PMID: 19103995 [PubMed - indexed for MEDLINE]Related articles

Computational modeling of LDL and albumin transport in an in vivo CT image-based human right coronary artery.

Sun N, Torii R, Wood NB, Hughes AD, Thom SA, Xu XY.

J Biomech Eng. 2009 Feb;131(2):021003.PMID: 19102562 [PubMed - indexed for MEDLINE]Related articles

Efficacy of novel lipid-formulated whole bacterial cell vaccines against Mycobacterium avium subsp. paratuberculosis in sheep.

Griffin JF, Hughes AD, Liggett S, Farquhar PA, Mackintosh CG, Bakker D.

Vaccine. 2009 Feb 5;27(6):911-8. Epub 2008 Dec 4.PMID: 19059295 [PubMed - indexed for MEDLINE]Related articles

Evidence of improved regional myocardial function in patients with chronic stable angina and apparent normal ventricular function--a tissue Doppler study before and after percutaneous coronary intervention.

Diller GP, Wasan BS, Thom SA, Foale RA, Hughes AD, Francis DP, Mayet J.

J Am Soc Echocardiogr. 2009 Feb;22(2):177-82. Epub 2008 Nov 20.PMID: 19022622 [PubMed - indexed for MEDLINE]Related articles

Ethnicity and left ventricular diastolic function in hypertension an ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) substudy.

Sharp A, Tapp R, Francis DP, McG Thom SA, Hughes AD, Stanton AV, Zambanini A, Chaturvedi N, Byrd S, Poulter NR, Sever PS, Mayet J.

J Am Coll Cardiol. 2008 Sep 16;52(12):1015-21.PMID: 18786484 [PubMed - indexed for MEDLINE]Related articles

Differences in cardiac microcirculatory wave patterns between the proximal left mainstem and proximal right coronary artery.

Hadjiloizou N, Davies JE, Malik IS, Aguado-Sierra J, Willson K, Foale RA, Parker KH, Hughes AD, Francis DP, Mayet J.

Am J Physiol Heart Circ Physiol. 2008 Sep;295(3):H1198-H1205. Epub 2008 Jul 18.PMID: 18641272 [PubMed - indexed for MEDLINE]Related articlesFree article

What is the role of the aorta in directing coronary blood flow?

Davies JE, Parker KH, Francis DP, Hughes AD, Mayet J.

Heart. 2008 Dec;94(12):1545-7. Epub 2008 Jul 16. No abstract available. PMID: 18632832 [PubMed - indexed for MEDLINE]Related articles

Ethnic differences in retinal microvascular structure.

Tillin T, Evans RM, Witt NW, Sharp PS, McKeigue PM, Chaturvedi N, Hughes AD.

Diabetologia. 2008 Sep;51(9):1719-22. Epub 2008 Jul 15.PMID: 18626625 [PubMed - indexed for MEDLINE]Related articles

Effect of antihypertensive treatment on retinal microvascular changes in hypertension.

Hughes AD, Stanton AV, Jabbar AS, Chapman N, Martinez-Perez ME, McG Thom SA.

J Hypertens. 2008 Aug;26(8):1703-7.PMID: 18622251 [PubMed - indexed for MEDLINE]Related articles

Induction of oscillatory ventilation pattern using dynamic modulation of heart rate through a pacemaker.

Manisty CH, Willson K, Davies JE, Whinnett ZI, Baruah R, Mebrate Y, Kanagaratnam P, Peters NS, Hughes AD, Mayet J, Francis DP.

Am J Physiol Regul Integr Comp Physiol. 2008 Jul;295(1):R219-27. Epub 2008 May 7.PMID: 18463195 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral augmentation index and wave reflection in the radial artery.

Hughes AD, Davies JE, Francis D, Mayet J, Parker KH.

Hypertension. 2008 Jun;51(6):e45-6; author reply e47. Epub 2008 Apr 28. No abstract available. PMID: 18443231 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of elastic compression stockings on wall shear stress in deep and superficial veins of the calf.

Downie SP, Raynor SM, Firmin DN, Wood NB, Thom SA, Hughes AD, Parker KH, Wolfe JH, Xu XY.

Am J Physiol Heart Circ Physiol. 2008 May;294(5):H2112-20. Epub 2008 Mar 7.PMID: 18326802 [PubMed - indexed for MEDLINE]Related articlesFree article

The atrioventricular delay of cardiac resynchronization can be optimized hemodynamically during exercise and predicted from resting measurements.

Whinnett ZI, Briscoe C, Davies JE, Willson K, Manisty CH, Davies DW, Peters NS, Kanagaratnam P, Hughes AD, Mayet J, Francis DP.

Heart Rhythm. 2008 Mar;5(3):378-86. Epub 2007 Dec 4.PMID: 18313595 [PubMed - indexed for MEDLINE]Related articles

Retinal vascular lesions in patients of Caucasian and Asian origin with type 2 diabetes: baseline results from the ADVANCE Retinal Measurements (AdRem) study.

Stolk RP, van Schooneveld MJ, Cruickshank JK, Hughes AD, Stanton A, Lu J, Patel A, Thom SA, Grobbee DE, Vingerling JR; AdRem Project Team and ADVANCE Management Committee.

Diabetes Care. 2008 Apr;31(4):708-13. Epub 2008 Jan 9.PMID: 18184903 [PubMed - indexed for MEDLINE]Related articlesFree article

A pattern recognition based fluorescence quenching assay for the detection and identification of nitrated explosive analytes.

Hughes AD, Glenn IC, Patrick AD, Ellington A, Anslyn EV.

Chemistry. 2008;14(6):1822-7.PMID: 18161712 [PubMed]Related articles

Improvement of a retinal blood vessel segmentation method using the Insight Segmentation and Registration Toolkit (ITK).

Martinez-Perez M, Hughes AD, Thom SA, Parker KH.

Conf Proc IEEE Eng Med Biol Soc. 2007;2007:892-5.PMID: 18002100 [PubMed - indexed for MEDLINE]Related articles

Impact of size at birth on the microvasculature: the Avon Longitudinal Study of Parents and Children.

Tapp RJ, Williams C, Witt N, Chaturvedi N, Evans R, Thom SA, Hughes AD, Ness A.

Pediatrics. 2007 Nov;120(5):e1225-8.PMID: 17974715 [PubMed - indexed for MEDLINE]Related articlesFree article

Arterial pulse wave velocity in coronary arteries.

Aguado-Sierra J, Parker KH, Davies JE, Francis D, Hughes AD, Mayet J.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:867-70.PMID: 17946867 [PubMed - indexed for MEDLINE]Related articles

The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression.

Achour M, Jacq X, Rondé P, Alhosin M, Charlot C, Chataigneau T, Jeanblanc M, Macaluso M, Giordano A, Hughes AD, Schini-Kerth VB, Bronner C.

Oncogene. 2008 Apr 3;27(15):2187-97. Epub 2007 Oct 15.PMID: 17934516 [PubMed - indexed for MEDLINE]Related articles

Platelet and leukocyte activation, atherosclerosis and inflammation in European and South Asian men.

Dotsenko O, Chaturvedi N, Thom SA, Wright AR, Mayet J, Shore A, Schalkwijk C, Hughes AD.

J Thromb Haemost. 2007 Oct;5(10):2036-42.PMID: 17883700 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficiency, reproducibility and agreement of five different hemodynamic measures for optimization of cardiac resynchronization therapy.

Whinnett ZI, Davies JE, Nott G, Willson K, Manisty CH, Peters NS, Kanagaratnam P, Davies DW, Hughes AD, Mayet J, Francis DP.

Int J Cardiol. 2008 Sep 26;129(2):216-26. Epub 2007 Sep 18.PMID: 17881070 [PubMed - indexed for MEDLINE]Related articles

Src family tyrosine kinases mediate contraction of rat isolated tail arteries in response to a hyposmotic stimulus.

Wijetunge S, Hughes AD.

J Hypertens. 2007 Sep;25(9):1871-8.PMID: 17762651 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of MRI in investigating the effects of elastic compression stockings on the deformation of the superficial and deep veins in the lower leg.

Downie SP, Firmin DN, Wood NB, Thom SA, Hughes AD, Wolfe JN, Xu XY.

J Magn Reson Imaging. 2007 Jul;26(1):80-5.PMID: 17659543 [PubMed - indexed for MEDLINE]Related articles

Left ventricular hypertrophy induced by aortic banding impairs relaxation of isolated coronary arteries.

McGoldrick RB, Kingsbury M, Turner MA, Sheridan DJ, Hughes AD.

Clin Sci (Lond). 2007 Dec;113(12):473-8.PMID: 17635104 [PubMed - indexed for MEDLINE]Related articles

Influence of pulsatile flow on LDL transport in the arterial wall.

Sun N, Wood NB, Hughes AD, Thom SA, Xu XY.

Ann Biomed Eng. 2007 Oct;35(10):1782-90. Epub 2007 Jul 14.PMID: 17629792 [PubMed - indexed for MEDLINE]Related articles

The Clinical Assessment of Retinal Microvascular Structure and Therapeutic Implications.

Hughes AD.

Curr Treat Options Cardiovasc Med. 2007 Jun;9(3):236-241.PMID: 17601388 [PubMed - as supplied by publisher]Related articles

Drug effects on the mechanical properties of large arteries in humans.

Hope SA, Hughes AD.

Clin Exp Pharmacol Physiol. 2007 Jul;34(7):688-93. Review.PMID: 17581231 [PubMed - indexed for MEDLINE]Related articles

Analysis of complex flow and the relationship between blood pressure, wall shear stress, and intima-media thickness in the human carotid artery.

Augst AD, Ariff B, McG Thom SA, Xu XY, Hughes AD.

Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H1031-7. Epub 2007 Apr 20.PMID: 17449549 [PubMed - indexed for MEDLINE]Related articlesFree article

A cationic host displaying positive cooperativity in water.

Hughes AD, Anslyn EV.

Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6538-43. Epub 2007 Apr 9.PMID: 17420472 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced systolic wave generation and increased peripheral wave reflection in chronic heart failure.

Curtis SL, Zambanini A, Mayet J, McG Thom SA, Foale R, Parker KH, Hughes AD.

Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H557-62. Epub 2007 Mar 30.PMID: 17400718 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of transmural pressure and wall shear stress on LDL accumulation in the arterial wall: a numerical study using a multilayered model.

Sun N, Wood NB, Hughes AD, Thom SA, Yun Xu X.

Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3148-57. Epub 2007 Feb 2.PMID: 17277019 [PubMed - indexed for MEDLINE]Related articlesFree article

The integration of medical imaging and computational fluid dynamics for measuring wall shear stress in carotid arteries.

Glor FP, Ariff B, Hughes AD, Crowe LA, Verdonck PR, Barratt DC, McG Thom SA, Firmin DN, Xu XY.

Conf Proc IEEE Eng Med Biol Soc. 2004;2:1415-8.PMID: 17271959 [PubMed]Related articles