PubMed

Re: Fifty years ago--schizophrenia: a major public health problem.

Hubbard RC.

Conn Med. 2009 Aug;73(7):445-6. No abstract available. PMID: 19711509 [PubMed - indexed for MEDLINE]Related articles

The analgesic efficacy of intramuscular parecoxib sodium in postoperative dental pain.

Mehlisch DR, Desjardins PJ, Daniels S, Hubbard RC.

J Am Dent Assoc. 2004 Nov;135(11):1578-90.PMID: 15622663 [PubMed - indexed for MEDLINE]Related articlesFree article

A clinical trial demonstrates the analgesic activity of intravenous parecoxib sodium compared with ketorolac or morphine after gynecologic surgery with laparotomy.

Bikhazi GB, Snabes MC, Bajwa ZH, Davis DJ, LeComte D, Traylor L, Hubbard RC.

Am J Obstet Gynecol. 2004 Oct;191(4):1183-91.PMID: 15507939 [PubMed - indexed for MEDLINE]Related articles

Parecoxib sodium demonstrates gastrointestinal safety comparable to placebo in healthy subjects.

Harris SI, Stoltz RR, LeComte D, Hubbard RC.

J Clin Gastroenterol. 2004 Aug;38(7):575-80.PMID: 15232360 [PubMed - indexed for MEDLINE]Related articles

Analgesic efficacy of preoperative parecoxib sodium in an orthopedic pain model.

Desjardins PJ, Traylor L, Hubbard RC.

J Am Podiatr Med Assoc. 2004 May-Jun;94(3):305-14.PMID: 15153593 [PubMed - indexed for MEDLINE]Related articles

Parecoxib sodium, an injectable COX-2-specific inhibitor, does not affect unfractionated heparin-regulated blood coagulation parameters.

Noveck RJ, Hubbard RC.

J Clin Pharmacol. 2004 May;44(5):474-80.PMID: 15102867 [PubMed - indexed for MEDLINE]Related articles

Single doses of parecoxib sodium intravenously are as effective as ketorolac in reducing pain after oral surgery.

Mehlisch DR, Desjardins PJ, Daniels S, Hubbard RC.

J Oral Maxillofac Surg. 2003 Sep;61(9):1030-7.PMID: 12966478 [PubMed - indexed for MEDLINE]Related articles

Efficacy and safety of the cyclooxygenase 2 inhibitors parecoxib and valdecoxib in patients undergoing coronary artery bypass surgery.

Ott E, Nussmeier NA, Duke PC, Feneck RO, Alston RP, Snabes MC, Hubbard RC, Hsu PH, Saidman LJ, Mangano DT; Multicenter Study of Perioperative Ischemia (McSPI) Research Group; Ischemia Research and Education Foundation (IREF) Investigators.

J Thorac Cardiovasc Surg. 2003 Jun;125(6):1481-92.PMID: 12830070 [PubMed - indexed for MEDLINE]Related articles

Parecoxib sodium, a parenteral cyclooxygenase 2 selective inhibitor, improves morphine analgesia and is opioid-sparing following total hip arthroplasty.

Malan TP Jr, Marsh G, Hakki SI, Grossman E, Traylor L, Hubbard RC.

Anesthesiology. 2003 Apr;98(4):950-6.PMID: 12657858 [PubMed - indexed for MEDLINE]Related articlesFree article

Parecoxib sodium has opioid-sparing effects in patients undergoing total knee arthroplasty under spinal anaesthesia.

Hubbard RC, Naumann TM, Traylor L, Dhadda S.

Br J Anaesth. 2003 Feb;90(2):166-72.PMID: 12538372 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and safety of intravenous parecoxib sodium in relieving acute postoperative pain following gynecologic laparotomy surgery.

Barton SF, Langeland FF, Snabes MC, LeComte D, Kuss ME, Dhadda SS, Hubbard RC.

Anesthesiology. 2002 Aug;97(2):306-14.PMID: 12151917 [PubMed - indexed for MEDLINE]Related articlesFree article

Intravenous parecoxib sodium foracute pain after orthopedic knee surgery.

Rasmussen GL, Steckner K, Hogue C, Torri S, Hubbard RC.

Am J Orthop. 2002 Jun;31(6):336-43.PMID: 12083587 [PubMed - indexed for MEDLINE]Related articles

Upper GI mucosal effects of parecoxib sodium in healthy elderly subjects.

Stoltz RR, Harris SI, Kuss ME, LeComte D, Talwalker S, Dhadda S, Hubbard RC.

Am J Gastroenterol. 2002 Jan;97(1):65-71.PMID: 11808971 [PubMed - indexed for MEDLINE]Related articles

Comparative efficacy and safety of celecoxib and naproxen in the treatment of osteoarthritis of the hip.

Kivitz AJ, Moskowitz RW, Woods E, Hubbard RC, Verburg KM, Lefkowith JB, Geis GS.

J Int Med Res. 2001 Nov-Dec;29(6):467-79.PMID: 11803730 [PubMed - indexed for MEDLINE]Related articles

Upper gastrointestinal safety evaluation of parecoxib sodium, a new parenteral cyclooxygenase-2-specific inhibitor, compared with ketorolac, naproxen, and placebo.

Harris SI, Kuss M, Hubbard RC, Goldstein JL.

Clin Ther. 2001 Sep;23(9):1422-8.PMID: 11589257 [PubMed - indexed for MEDLINE]Related articles

A pharmacokinetic study of intramuscular (i.m.) parecoxib sodium in normal subjects.

Karim A, Laurent A, Slater ME, Kuss ME, Qian J, Crosby-Sessoms SL, Hubbard RC.

J Clin Pharmacol. 2001 Oct;41(10):1111-9.PMID: 11583480 [PubMed - indexed for MEDLINE]Related articles

The injectable cyclooxygenase-2-specific inhibitor parecoxib sodium has analgesic efficacy when administered preoperatively.

Desjardins PJ, Grossman EH, Kuss ME, Talwalker S, Dhadda S, Baum D, Hubbard RC.

Anesth Analg. 2001 Sep;93(3):721-7.PMID: 11524347 [PubMed - indexed for MEDLINE]Related articlesFree article

A double-blind, randomized comparison of intramuscularly and intravenously administered parecoxib sodium versus ketorolac and placebo in a post-oral surgery pain model.

Daniels SE, Grossman EH, Kuss ME, Talwalker S, Hubbard RC.

Clin Ther. 2001 Jul;23(7):1018-31.PMID: 11519767 [PubMed - indexed for MEDLINE]Related articles

Reduced incidence of gastroduodenal ulcers with celecoxib, a novel cyclooxygenase-2 inhibitor, compared to naproxen in patients with arthritis.

Goldstein JL, Correa P, Zhao WW, Burr AM, Hubbard RC, Verburg KM, Geis GS.

Am J Gastroenterol. 2001 Apr;96(4):1019-27.PMID: 11316141 [PubMed - indexed for MEDLINE]Related articles

Comparison of once-daily and twice-daily administration of celecoxib for the treatment of osteoarthritis of the knee.

Williams GW, Hubbard RC, Yu SS, Zhao W, Geis GS.

Clin Ther. 2001 Feb;23(2):213-27.PMID: 11293555 [PubMed - indexed for MEDLINE]Related articles

Reduced risk of upper gastrointestinal ulcer complications with celecoxib, a novel COX-2 inhibitor.

Goldstein JL, Silverstein FE, Agrawal NM, Hubbard RC, Kaiser J, Maurath CJ, Verburg KM, Geis GS.

Am J Gastroenterol. 2000 Jul;95(7):1681-90.PMID: 10925968 [PubMed - indexed for MEDLINE]Related articles

Celecoxib does not significantly alter the pharmacokinetics or hypoprothrombinemic effect of warfarin in healthy subjects.

Karim A, Tolbert D, Piergies A, Hubbard RC, Harper K, Wallemark CB, Slater M, Geis GS.

J Clin Pharmacol. 2000 Jun;40(6):655-63.PMID: 10868317 [PubMed - indexed for MEDLINE]Related articles

Treatment of osteoarthritis with a once-daily dosing regimen of celecoxib: a randomized, controlled trial.

Williams GW, Ettlinger RE, Ruderman EM, Hubbard RC, Lonien ME, Yu SS, Zhao W, Geis GS.

J Clin Rheumatol. 2000 Apr;6(2):65-74.PMID: 19078452 [PubMed - in process]Related articles

Effects of celecoxib, a novel cyclooxygenase-2 inhibitor, on platelet function in healthy adults: a randomized, controlled trial.

Leese PT, Hubbard RC, Karim A, Isakson PC, Yu SS, Geis GS.

J Clin Pharmacol. 2000 Feb;40(2):124-32.PMID: 10664917 [PubMed - indexed for MEDLINE]Related articles

Celecoxib versus diclofenac in long-term management of rheumatoid arthritis: randomised double-blind comparison.

Emery P, Zeidler H, Kvien TK, Guslandi M, Naudin R, Stead H, Verburg KM, Isakson PC, Hubbard RC, Geis GS.

Lancet. 1999 Dec 18-25;354(9196):2106-11.PMID: 10609815 [PubMed - indexed for MEDLINE]Related articles

Celecoxib, a specific COX-2 inhibitor, has no significant effect on methotrexate pharmacokinetics in patients with rheumatoid arthritis.

Karim A, Tolbert DS, Hunt TL, Hubbard RC, Harper KM, Geis GS.

J Rheumatol. 1999 Dec;26(12):2539-43.PMID: 10606360 [PubMed - indexed for MEDLINE]Related articles

Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: a randomized controlled trial.

Simon LS, Weaver AL, Graham DY, Kivitz AJ, Lipsky PE, Hubbard RC, Isakson PC, Verburg KM, Yu SS, Zhao WW, Geis GS.

JAMA. 1999 Nov 24;282(20):1921-8.PMID: 10580457 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of osteoarthritis with celecoxib, a cyclooxygenase-2 inhibitor: a randomized controlled trial.

Bensen WG, Fiechtner JJ, McMillen JI, Zhao WW, Yu SS, Woods EM, Hubbard RC, Isakson PC, Verburg KM, Geis GS.

Mayo Clin Proc. 1999 Nov;74(11):1095-105.PMID: 10560596 [PubMed - indexed for MEDLINE]Related articles

Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects.

Simon LS, Lanza FL, Lipsky PE, Hubbard RC, Talwalker S, Schwartz BD, Isakson PC, Geis GS.

Arthritis Rheum. 1998 Sep;41(9):1591-602.PMID: 9751091 [PubMed - indexed for MEDLINE]Related articlesFree article

Conversion from twice- to once-daily extended-release theophylline treatment in patients with reversible airway obstruction.

Berkowitz RB, Tinkelman DG, Marcoux JP, Rooklin AR, Zeitz HJ, Rennard SI, Moss BA, Hubbard RC, Lorber RR.

J Asthma. 1995;32(4):275-84.PMID: 7629003 [PubMed - indexed for MEDLINE]Related articles

Legalize drugs.

Hubbard RC.

Conn Med. 1994 May;58(5):312. No abstract available. PMID: 8076464 [PubMed - indexed for MEDLINE]Related articles

Recombinant secretory leukoprotease inhibitor augments glutathione levels in lung epithelial lining fluid.

Gillissen A, Birrer P, McElvaney NG, Buhl R, Vogelmeier C, Hoyt RF Jr, Hubbard RC, Crystal RG.

J Appl Physiol. 1993 Aug;75(2):825-32.PMID: 7901193 [PubMed - indexed for MEDLINE]Related articles

Intravenous recombinant secretory leukoprotease inhibitor augments antineutrophil elastase defense.

Birrer P, McElvaney NG, Gillissen A, Hoyt RF, Bloedow DC, Hubbard RC, Crystal RG.

J Appl Physiol. 1992 Jul;73(1):317-23.PMID: 1354669 [PubMed - indexed for MEDLINE]Related articles

A preliminary study of aerosolized recombinant human deoxyribonuclease I in the treatment of cystic fibrosis.

Hubbard RC, McElvaney NG, Birrer P, Shak S, Robinson WW, Jolley C, Wu M, Chernick MS, Crystal RG.

N Engl J Med. 1992 Mar 19;326(12):812-5. No abstract available. PMID: 1538726 [PubMed - indexed for MEDLINE]Related articles

Augmentation of functional prostaglandin E levels on the respiratory epithelial surface by aerosol administration of prostaglandin E.

Borok Z, Gillissen A, Buhl R, Hoyt RF, Hubbard RC, Ozaki T, Rennard SI, Crystal RG.

Am Rev Respir Dis. 1991 Nov;144(5):1080-4.PMID: 1952435 [PubMed - indexed for MEDLINE]Related articles

Use of a highly purified alpha 1-antitrypsin standard to establish ranges for the common normal and deficient alpha 1-antitrypsin phenotypes.

Brantly ML, Wittes JT, Vogelmeier CF, Hubbard RC, Fells GA, Crystal RG.

Chest. 1991 Sep;100(3):703-8.PMID: 1889260 [PubMed - indexed for MEDLINE]Related articlesFree article

Neutrophil accumulation in the lung in alpha 1-antitrypsin deficiency. Spontaneous release of leukotriene B4 by alveolar macrophages.

Hubbard RC, Fells G, Gadek J, Pacholok S, Humes J, Crystal RG.

J Clin Invest. 1991 Sep;88(3):891-7.PMID: 1653278 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of glutathione aerosol on oxidant-antioxidant imbalance in idiopathic pulmonary fibrosis.

Borok Z, Buhl R, Grimes GJ, Bokser AD, Hubbard RC, Holroyd KJ, Roum JH, Czerski DB, Cantin AM, Crystal RG.

Lancet. 1991 Jul 27;338(8761):215-6.PMID: 1676780 [PubMed - indexed for MEDLINE]Related articles

Expression of the secretory leukoprotease inhibitor gene in epithelial cells.

Abe T, Kobayashi N, Yoshimura K, Trapnell BC, Kim H, Hubbard RC, Brewer MT, Thompson RC, Crystal RG.

J Clin Invest. 1991 Jun;87(6):2207-15.PMID: 1674946 [PubMed - indexed for MEDLINE]Related articlesFree article

Risk factors for emphysema. Cigarette smoking is associated with a reduction in the association rate constant of lung alpha 1-antitrypsin for neutrophil elastase.

Ogushi F, Hubbard RC, Vogelmeier C, Fells GA, Crystal RG.

J Clin Invest. 1991 Mar;87(3):1060-5.PMID: 1999486 [PubMed - indexed for MEDLINE]Related articlesFree article

Aerosol alpha 1-antitrypsin treatment for cystic fibrosis.

McElvaney NG, Hubbard RC, Birrer P, Chernick MS, Caplan DB, Frank MM, Crystal RG.

Lancet. 1991 Feb 16;337(8738):392-4.PMID: 1671425 [PubMed - indexed for MEDLINE]Related articles

Anti-neutrophil elastase defense of the normal human respiratory epithelial surface provided by the secretory leukoprotease inhibitor.

Vogelmeier C, Hubbard RC, Fells GA, Schnebli HP, Thompson RC, Fritz H, Crystal RG.

J Clin Invest. 1991 Feb;87(2):482-8.PMID: 1671391 [PubMed - indexed for MEDLINE]Related articlesFree article

Aerosolization of recombinant SLPI to augment antineutrophil elastase protection of pulmonary epithelium.

Vogelmeier C, Buhl R, Hoyt RF, Wilson E, Fells GA, Hubbard RC, Schnebli HP, Thompson RC, Crystal RG.

J Appl Physiol. 1990 Nov;69(5):1843-8.PMID: 2272977 [PubMed - indexed for MEDLINE]Related articles

Antioxidant macromolecules in the epithelial lining fluid of the normal human lower respiratory tract.

Cantin AM, Fells GA, Hubbard RC, Crystal RG.

J Clin Invest. 1990 Sep;86(3):962-71.PMID: 2394842 [PubMed - indexed for MEDLINE]Related articlesFree article

Augmentation of glutathione in the fluid lining the epithelium of the lower respiratory tract by directly administering glutathione aerosol.

Buhl R, Vogelmeier C, Critenden M, Hubbard RC, Hoyt RF Jr, Wilson EM, Cantin AM, Crystal RG.

Proc Natl Acad Sci U S A. 1990 Jun;87(11):4063-7.PMID: 2349219 [PubMed - indexed for MEDLINE]Related articlesFree article

Augmentation therapy of alpha 1-antitrypsin deficiency.

Hubbard RC, Crystal RG.

Eur Respir J Suppl. 1990 Mar;9:44s-52s.PMID: 2340051 [PubMed - indexed for MEDLINE]Related articles

Strategies for aerosol therapy of alpha 1-antitrypsin deficiency by the aerosol route.

Hubbard RC, Crystal RG.

Lung. 1990;168 Suppl:565-78.PMID: 2117165 [PubMed - indexed for MEDLINE]Related articles

Molecular basis of alpha 1-antitrypsin deficiency and emphysema associated with the alpha 1-antitrypsin Mmineral springs allele.

Curiel DT, Vogelmeier C, Hubbard RC, Stier LE, Crystal RG.

Mol Cell Biol. 1990 Jan;10(1):47-56.PMID: 1967187 [PubMed - indexed for MEDLINE]Related articlesFree article

Recombinant DNA-produced alpha 1-antitrypsin administered by aerosol augments lower respiratory tract antineutrophil elastase defenses in individuals with alpha 1-antitrypsin deficiency.

Hubbard RC, McElvaney NG, Sellers SE, Healy JT, Czerski DB, Crystal RG.

J Clin Invest. 1989 Oct;84(4):1349-54.PMID: 2794066 [PubMed - indexed for MEDLINE]Related articlesFree article

Anti-neutrophil-elastase defenses of the lower respiratory tract in alpha 1-antitrypsin deficiency directly augmented with an aerosol of alpha 1-antitrypsin.

Hubbard RC, Brantly ML, Sellers SE, Mitchell ME, Crystal RG.

Ann Intern Med. 1989 Aug 1;111(3):206-12.PMID: 2787611 [PubMed - indexed for MEDLINE]Related articles