PubMed

Delivering the goods: realizing the clinical potential of RNAi.

Howard KA.

Nanomed. 2009 Aug;4(6):595-8. No abstract available. PMID: 19663585 [PubMed - indexed for MEDLINE]Related articles

Size-Dependent Accumulation of PEGylated Silane-Coated Magnetic Iron Oxide Nanoparticles in Murine Tumors.

Larsen EK, Nielsen T, Wittenborn T, Birkedal H, Vorup-Jensen T, Jakobsen MH, Ostergaard L, Horsman MR, Besenbacher F, Howard KA, Kjems J.

ACS Nano. 2009 Jul 2. [Epub ahead of print]PMID: 19572620 [PubMed - as supplied by publisher]Related articles

Effect of physicochemical properties on intranasal nanoparticle transit into murine olfactory epithelium.

Mistry A, Glud SZ, Kjems J, Randel J, Howard KA, Stolnik S, Illum L.

J Drug Target. 2009 Aug;17(7):543-52.PMID: 19530905 [PubMed - indexed for MEDLINE]Related articles

RNAi using a chitosan/siRNA nanoparticle system: in vitro and in vivo applications.

Andersen MØ, Howard KA, Kjems J.

Methods Mol Biol. 2009;555:77-86.PMID: 19495689 [PubMed - indexed for MEDLINE]Related articles

Naked siLNA-mediated gene silencing of lung bronchoepithelium EGFP expression after intravenous administration.

Glud SZ, Bramsen JB, Dagnaes-Hansen F, Wengel J, Howard KA, Nyengaard JR, Kjems J.

Oligonucleotides. 2009 Jun;19(2):163-8.PMID: 19441893 [PubMed - indexed for MEDLINE]Related articles

The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice.

Gao S, Dagnaes-Hansen F, Nielsen EJ, Wengel J, Besenbacher F, Howard KA, Kjems J.

Mol Ther. 2009 Jul;17(7):1225-33. Epub 2009 Apr 28.PMID: 19401674 [PubMed - indexed for MEDLINE]Related articles

Delivery of RNA interference therapeutics using polycation-based nanoparticles.

Howard KA.

Adv Drug Deliv Rev. 2009 Jul 25;61(9):710-20. Epub 2009 Apr 5. Review.PMID: 19356738 [PubMed - indexed for MEDLINE]Related articles

Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model.

Howard KA, Paludan SR, Behlke MA, Besenbacher F, Deleuran B, Kjems J.

Mol Ther. 2009 Jan;17(1):162-8. Epub 2008 Sep 30.PMID: 18827803 [PubMed - indexed for MEDLINE]Related articles

Investigation of particle-functionalized tissue engineering scaffolds using X-ray tomographic microscopy.

Nygaard JV, Andersen MØ, Howard KA, Foss M, Bünger C, Kjems J, Besenbacher F.

Biotechnol Bioeng. 2008 Jul 1;100(4):820-9.PMID: 18306420 [PubMed - indexed for MEDLINE]Related articles

Polycation-based nanoparticle delivery for improved RNA interference therapeutics.

Howard KA, Kjems J.

Expert Opin Biol Ther. 2007 Dec;7(12):1811-22. Review.PMID: 18034647 [PubMed - indexed for MEDLINE]Related articles

Intracellular siRNA and precursor miRNA trafficking using bioresponsive copolypeptides.

Rahbek UL, Howard KA, Oupicky D, Manickam DS, Dong M, Nielsen AF, Hansen TB, Besenbacher F, Kjems J.

J Gene Med. 2008 Jan;10(1):81-93.PMID: 18000993 [PubMed - indexed for MEDLINE]Related articles

Delivery of siRNA from lyophilized polymeric surfaces.

Andersen MØ, Howard KA, Paludan SR, Besenbacher F, Kjems J.

Biomaterials. 2008 Feb;29(4):506-12. Epub 2007 Oct 24.PMID: 17950838 [PubMed - indexed for MEDLINE]Related articles

Direct force measurements between siRNA and chitosan molecules using force spectroscopy.

Xu S, Dong M, Liu X, Howard KA, Kjems J, Besenbacher F.

Biophys J. 2007 Aug 1;93(3):952-9. Epub 2007 May 4.PMID: 17483179 [PubMed - indexed for MEDLINE]Related articlesFree article

Nanocarrier stimuli-activated gene delivery.

Howard KA, Dong M, Oupicky D, Bisht HS, Buss C, Besenbacher F, Kjems J.

Small. 2007 Jan;3(1):54-7. No abstract available. PMID: 17294468 [PubMed - indexed for MEDLINE]Related articles

The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing.

Liu X, Howard KA, Dong M, Andersen MØ, Rahbek UL, Johnsen MG, Hansen OC, Besenbacher F, Kjems J.

Biomaterials. 2007 Feb;28(6):1280-8.PMID: 17126901 [PubMed - indexed for MEDLINE]Related articles

RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system.

Howard KA, Rahbek UL, Liu X, Damgaard CK, Glud SZ, Andersen MØ, Hovgaard MB, Schmitz A, Nyengaard JR, Besenbacher F, Kjems J.

Mol Ther. 2006 Oct;14(4):476-84. Epub 2006 Jul 10.PMID: 16829204 [PubMed - indexed for MEDLINE]Related articles

Protection against bubonic and pneumonic plague with a single dose microencapsulated sub-unit vaccine.

Elvin SJ, Eyles JE, Howard KA, Ravichandran E, Somavarappu S, Alpar HO, Williamson ED.

Vaccine. 2006 May 15;24(20):4433-9. Epub 2005 Dec 21.PMID: 16546306 [PubMed - indexed for MEDLINE]Related articles

How much did cold shock and swimming failure contribute to drowning deaths in the fishing industry in British Columbia 1976-2002?

Brooks CJ, Howard KA, Neifer SK.

Occup Med (Lond). 2005 Sep;55(6):459-62. Epub 2005 May 4.PMID: 15871996 [PubMed - indexed for MEDLINE]Related articles

Depressive symptoms in and type of classroom placement for adolescents with LD.

Howard KA, Tryon GS.

J Learn Disabil. 2002 Mar-Apr;35(2):185-90.PMID: 15490745 [PubMed - indexed for MEDLINE]Related articles

Formulation of a microparticle carrier for oral polyplex-based DNA vaccines.

Howard KA, Li XW, Somavarapu S, Singh J, Green N, Atuah KN, Ozsoy Y, Seymour LW, Alpar HO.

Biochim Biophys Acta. 2004 Sep 24;1674(2):149-57.PMID: 15374619 [PubMed - indexed for MEDLINE]Related articles

Undertreatment of osteoporosis in residents of nursing homes: population-based study with use of the Systematic Assessment of Geriatric Drug Use via Epidemiology (SAGE) database.

Rojas-Fernandez CH, Lapane KL, MacKnight C, Howard KA.

Endocr Pract. 2002 Sep-Oct;8(5):335-42.PMID: 15259120 [PubMed - indexed for MEDLINE]Related articles

Determination of the selenium requirement in kittens.

Wedekind KJ, Howard KA, Backus RC, Yu S, Morris JG, Rogers QR.

J Anim Physiol Anim Nutr (Berl). 2003 Oct;87(9-10):315-23.PMID: 14507414 [PubMed - indexed for MEDLINE]Related articles

Alcohol coverage in California newspapers: frequency, prominence, and framing.

Myhre SL, Saphir MN, Flora JA, Howard KA, Gonzalez EM.

J Public Health Policy. 2002;23(2):172-90.PMID: 12108117 [PubMed - indexed for MEDLINE]Related articles

The development of polyplex-based DNA vaccines.

Howard KA, Alpar HO.

J Drug Target. 2002 Mar;10(2):143-51. Review.PMID: 12074541 [PubMed - indexed for MEDLINE]Related articles

Independent evaluation of the California Tobacco Control Program: relationships between program exposure and outcomes, 1996-1998.

Rohrbach LA, Howard-Pitney B, Unger JB, Dent CW, Howard KA, Cruz TB, Ribisl KM, Norman GJ, Fishbein H, Johnson CA.

Am J Public Health. 2002 Jun;92(6):975-83.PMID: 12036792 [PubMed - indexed for MEDLINE]Related articlesFree article

Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation.

Oupicky D, Ogris M, Howard KA, Dash PR, Ulbrich K, Seymour LW.

Mol Ther. 2002 Apr;5(4):463-72.PMID: 11945074 [PubMed - indexed for MEDLINE]Related articlesFree article

A low-selenium diet increases thyroxine and decreases 3,5,3'triiodothyronine in the plasma of kittens.

Yu S, Howard KA, Wedekind KJ, Morris JG, Rogers QR.

J Anim Physiol Anim Nutr (Berl). 2002 Feb;86(1-2):36-41.PMID: 11906571 [PubMed - indexed for MEDLINE]Related articles

What factors are associated with local enforcement of laws banning illegal tobacco sales to minors? A study of 182 law enforcement agencies in California.

Howard KA, Ribisl KM, Howard-Pitney B, Norman GJ, Rohrbach LA.

Prev Med. 2001 Aug;33(2 Pt 1):63-70.PMID: 11493037 [PubMed - indexed for MEDLINE]Related articles

Ethnic variation in peer influences on adolescent smoking.

Unger JB, Rohrbach LA, Cruz TB, Baezconde-Garbanati L, Howard KA, Palmer PH, Johnson CA.

Nicotine Tob Res. 2001 May;3(2):167-76.PMID: 11403731 [PubMed - indexed for MEDLINE]Related articles

The relationship between home smoking bans and exposure to state tobacco control efforts and smoking behaviors.

Norman GJ, Ribisl KM, Howard-Pitney B, Howard KA, Unger JB.

Am J Health Promot. 2000 Nov-Dec;15(2):81-8.PMID: 11194699 [PubMed - indexed for MEDLINE]Related articles

Influence of hydrophilicity of cationic polymers on the biophysical properties of polyelectrolyte complexes formed by self-assembly with DNA.

Howard KA, Dash PR, Read ML, Ward K, Tomkins LM, Nazarova O, Ulbrich K, Seymour LW.

Biochim Biophys Acta. 2000 Jul 26;1475(3):245-55.PMID: 10913823 [PubMed - indexed for MEDLINE]Related articles

Opinion leaders' support for tobacco control policies and participation in tobacco control activities.

Howard KA, Rogers T, Howard-Pitney B, Flora JA, Norman GJ, Ribisl KM.

Am J Public Health. 2000 Aug;90(8):1283-7.PMID: 10937010 [PubMed - indexed for MEDLINE]Related articlesFree article

Steric stabilization of poly-L-Lysine/DNA complexes by the covalent attachment of semitelechelic poly[N-(2-hydroxypropyl)methacrylamide].

Oupický D, Howard KA, Konák C, Dash PR, Ulbrich K, Seymour LW.

Bioconjug Chem. 2000 Jul-Aug;11(4):492-501.PMID: 10898570 [PubMed - indexed for MEDLINE]Related articles

Physicochemical and biological characterisation of an antisense oligonucleotide targeted against the bcl-2 mRNA complexed with cationic-hydrophilic copolymers.

Read ML, Dash PR, Clark A, Howard KA, Oupicky D, Toncheva V, Alpar HO, Schacht EH, Ulbrich K, Seymour LW.

Eur J Pharm Sci. 2000 May;10(3):169-77.PMID: 10767594 [PubMed - indexed for MEDLINE]Related articles

Decreased binding to proteins and cells of polymeric gene delivery vectors surface modified with a multivalent hydrophilic polymer and retargeting through attachment of transferrin.

Dash PR, Read ML, Fisher KD, Howard KA, Wolfert M, Oupicky D, Subr V, Strohalm J, Ulbrich K, Seymour LW.

J Biol Chem. 2000 Feb 11;275(6):3793-802.PMID: 10660529 [PubMed - indexed for MEDLINE]Related articlesFree article

Beliefs about the risks of guns in the home: analysis of a national survey.

Howard KA, Webster DW, Vernick JS.

Inj Prev. 1999 Dec;5(4):284-9.PMID: 10628918 [PubMed - indexed for MEDLINE]Related articlesFree article

Smoking bans in the home and car: Do those who really need them have them?

Norman GJ, Ribisl KM, Howard-Pitney B, Howard KA.

Prev Med. 1999 Dec;29(6 Pt 1):581-9.PMID: 10600441 [PubMed - indexed for MEDLINE]Related articles

Attitudes toward anti-tobacco policy among California youth: associations with smoking status, psychosocial variables and advocacy actions.

Unger JB, Rohrbach LA, Howard KA, Boley Cruz T, Johnson CA, Chen X.

Health Educ Res. 1999 Dec;14(6):751-63.PMID: 10585383 [PubMed - indexed for MEDLINE]Related articlesFree article

Which adults do underaged youth ask for cigarettes?

Ribisl KM, Norman GJ, Howard-Pitney B, Howard KA.

Am J Public Health. 1999 Oct;89(10):1561-4.PMID: 10511840 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of magnesium-deficient diet on serum and urine magnesium concentrations in healthy cats.

Norris CR, Christopher MM, Howard KA, Nelson RW.

Am J Vet Res. 1999 Sep;60(9):1159-63.PMID: 10490089 [PubMed - indexed for MEDLINE]Related articles

Magnesium requirement of kittens is increased by high dietary calcium.

Howard KA, Rogers QR, Morris JG.

J Nutr. 1998 Dec;128(12 Suppl):2601S-2602S. No abstract available. PMID: 9868215 [PubMed - indexed for MEDLINE]Related articlesFree article

Leukocytosis and thrombocytosis caused by consumption of a low magnesium and high calcium diet elevates whole-blood taurine concentration in cats.

Backus RC, Howard KA, Rogers QR, Morris JG.

J Nutr. 1998 Dec;128(12 Suppl):2581S-2583S. No abstract available. PMID: 9868208 [PubMed - indexed for MEDLINE]Related articlesFree article

The potency of dietary amino acids in elevating plasma cholecystokinin immunoreactivity in cats is related to amino acid hydrophobicity.

Backus RC, Howard KA, Rogers QR.

Regul Pept. 1997 Sep 26;72(1):31-40.PMID: 9404730 [PubMed - indexed for MEDLINE]Related articles

Particle uptake and translocation across epithelial membranes.

Thomas NW, Jenkins PG, Howard KA, Smith MW, Lavelle EC, Holland J, Davis SS.

J Anat. 1996 Dec;189 ( Pt 3):487-90. Review.PMID: 8982821 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship between driver's license renewal policies and fatal crashes involving drivers 70 years or older.

Levy DT, Vernick JS, Howard KA.

JAMA. 1995 Oct 4;274(13):1026-30.PMID: 7563452 [PubMed - indexed for MEDLINE]Related articles

Effect of infusion rate on thiopental dose-response relationships. Assessment of a pharmacokinetic-pharmacodynamic model.

Gentry WB, Krejcie TC, Henthorn TK, Shanks CA, Howard KA, Gupta DK, Avram MJ.

Anesthesiology. 1994 Aug;81(2):316-24; discussion 25A.PMID: 8053580 [PubMed - indexed for MEDLINE]Related articlesFree article

Determinants of thiopental induction dose requirements.

Avram MJ, Sanghvi R, Henthorn TK, Krejcie TC, Shanks CA, Fragen RJ, Howard KA, Kaczynski DA.

Anesth Analg. 1993 Jan;76(1):10-7.PMID: 8418708 [PubMed - indexed for MEDLINE]Related articles

Public opinion polling on gun policy.

Vernick JS, Teret SP, Howard KA, Teret MD, Wintemute GJ.

Health Aff (Millwood). 1993 Winter;12(4):198-208.PMID: 8125437 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of an adaptation period to soybean oil additions in the diets of young pigs.

Howard KA, Forsyth DM, Cline TR.

J Anim Sci. 1990 Mar;68(3):678-83.PMID: 2318731 [PubMed - indexed for MEDLINE]Related articlesFree article

Cloning the DdeI restriction-modification system using a two-step method.

Howard KA, Card C, Benner JS, Callahan HL, Maunus R, Silber K, Wilson G, Brooks JE.

Nucleic Acids Res. 1986 Oct 24;14(20):7939-51.PMID: 3022241 [PubMed - indexed for MEDLINE]Related articlesFree article