PubMed

Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase, SHIP2.

Suwa A, Yamamoto T, Sawada A, Minoura K, Hosogai N, Tahara A, Kurama T, Shimokawa T, Aramori I.

Br J Pharmacol. 2009 Oct;158(3):879-87. Epub 2009 Aug 19.PMID: 19694723 [PubMed - in process]Related articles

Two distinctive mechanisms leading to disruption of the SHOX transcription unit in a single family.

Izumi K, Nakano M, Kosaki K, Kosaki R, Hosogai N, Matsumoto H, Hasegawa T, Takahashi T, Kosaki K.

Am J Med Genet A. 2007 Dec 1;143A(23):2838-42. No abstract available. PMID: 17994568 [PubMed - indexed for MEDLINE]Related articles

Nitric oxide dysregulates adipocytokine expression in 3T3-L1 adipocytes.

Nozaki M, Fukuhara A, Segawa K, Okuno Y, Abe M, Hosogai N, Matsuda M, Komuro R, Shimomura I.

Biochem Biophys Res Commun. 2007 Dec 7;364(1):33-9. Epub 2007 Oct 1.PMID: 17931601 [PubMed - indexed for MEDLINE]Related articles

Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation.

Hosogai N, Fukuhara A, Oshima K, Miyata Y, Tanaka S, Segawa K, Furukawa S, Tochino Y, Komuro R, Matsuda M, Shimomura I.

Diabetes. 2007 Apr;56(4):901-11.PMID: 17395738 [PubMed - indexed for MEDLINE]Related articlesFree article

Visfatin in adipocytes is upregulated by hypoxia through HIF1alpha-dependent mechanism.

Segawa K, Fukuhara A, Hosogai N, Morita K, Okuno Y, Tanaka M, Nakagawa Y, Kihara S, Funahashi T, Komuro R, Matsuda M, Shimomura I.

Biochem Biophys Res Commun. 2006 Oct 27;349(3):875-82. Epub 2006 Jul 28.PMID: 16970912 [PubMed - indexed for MEDLINE]Related articles

FK614, a novel peroxisome proliferator-activated receptor gamma modulator, induces differential transactivation through a unique ligand-specific interaction with transcriptional coactivators.

Fujimura T, Sakuma H, Konishi S, Oe T, Hosogai N, Kimura C, Aramori I, Mutoh S.

J Pharmacol Sci. 2005 Dec;99(4):342-52. Epub 2005 Nov 26.PMID: 16314690 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of TS-1 based treatment and expression of thymidylate synthase and dihydropyrimidine dehydrogenase on oral squamous cell carcinoma.

Obara S, Yamamoto K, Hosogai N, Yoshimura Y.

Oral Oncol. 2005 Mar;41(3):276-82.PMID: 15743690 [PubMed - indexed for MEDLINE]Related articles

Phosphodiesterase type 5 inhibition ameliorates nephrotoxicity induced by cyclosporin A in spontaneous hypertensive rats.

Hosogai N, Tomita M, Hamada K, Ogawa T, Hirosumi J, Manda T, Mutoh S.

Eur J Pharmacol. 2003 Sep 12;477(2):171-8.PMID: 14519421 [PubMed - indexed for MEDLINE]Related articles

Enzyme activities of the nitric oxide-cGMP pathway in corpus cavernosum isolated from middle-aged rats.

Hosogai N, Takakura S, Manda T, Mutoh S.

Eur J Pharmacol. 2003 Jul 18;473(1):65-70.PMID: 12877939 [PubMed - indexed for MEDLINE]Related articles

Reciprocal regulation of cyclic GMP content by cyclic GMP-phosphodiesterase and guanylate cyclase in SHR with CsA-induced nephrotoxicity.

Hosogai N, Seki J, Goto T.

Br J Pharmacol. 2001 Nov;134(5):995-1002.PMID: 11682447 [PubMed - indexed for MEDLINE]Related articlesFree article

FR226807: a potent and selective phosphodiesterase type 5 inhibitor.

Hosogai N, Hamada K, Tomita M, Nagashima A, Takahashi T, Sekizawa T, Mizutani T, Urano Y, Kuroda A, Sawada K, Ozaki T, Seki J, Goto T.

Eur J Pharmacol. 2001 Oct 5;428(2):295-302.PMID: 11675048 [PubMed - indexed for MEDLINE]Related articles

Synthesis and characterization of orally active nonpeptide vasopressin V2 receptor antagonists.

Ohkawa T, Zenkoh T, Tomita M, Hosogai N, Hemmi K, Tanaka H, Setoi H.

Chem Pharm Bull (Tokyo). 1999 Apr;47(4):501-10.PMID: 10319429 [PubMed - indexed for MEDLINE]Related articles