PubMed

Clonal expansions in ulcerative colitis identify patients with neoplasia.

Salk JJ, Salipante SJ, Risques RA, Crispin DA, Li L, Bronner MP, Brentnall TA, Rabinovitch PS, Horwitz MS, Loeb LA.

Proc Natl Acad Sci U S A. 2009 Nov 19. [Epub ahead of print]PMID: 19926851 [PubMed - as supplied by publisher]Related articlesFree article

Adenovirus E3 MHC inhibitory genes but not TNF/Fas apoptotic inhibitory genes expressed in beta cells prevent autoimmune diabetes.

Horwitz MS, Efrat S, Christen U, von Herrath MG, Oldstone MB.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19450-4. Epub 2009 Nov 3.PMID: 19887639 [PubMed - in process]Related articles

Preventing viral-induced type 1 diabetes.

Richer MJ, Horwitz MS.

Ann N Y Acad Sci. 2009 Sep;1173:487-92. Review.PMID: 19758190 [PubMed - indexed for MEDLINE]Related articles

IL-6 during viral-induced chronic autoimmune myocarditis.

Poffenberger MC, Horwitz MS.

Ann N Y Acad Sci. 2009 Sep;1173:318-25.PMID: 19758168 [PubMed - indexed for MEDLINE]Related articles

Mutations in a gene encoding a midbody kelch protein in familial and sporadic classical Hodgkin lymphoma lead to binucleated cells.

Salipante SJ, Mealiffe ME, Wechsler J, Krem MM, Liu Y, Namkoong S, Bhagat G, Kirchhoff T, Offit K, Lynch H, Wiernik PH, Roshal M, McMaster ML, Tucker M, Fromm JR, Goldin LR, Horwitz MS.

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14920-5. Epub 2009 Aug 12.PMID: 19706467 [PubMed - indexed for MEDLINE]Related articles

Lack of IL-6 during coxsackievirus infection heightens the early immune response resulting in increased severity of chronic autoimmune myocarditis.

Poffenberger MC, Straka N, El Warry N, Fang D, Shanina I, Horwitz MS.

PLoS One. 2009 Jul 9;4(7):e6207.PMID: 19587788 [PubMed - indexed for MEDLINE]Related articlesFree article

Contributions to neutropenia from PFAAP5 (N4BP2L2), a novel protein mediating transcriptional repressor cooperation between Gfi1 and neutrophil elastase.

Salipante SJ, Rojas ME, Korkmaz B, Duan Z, Wechsler J, Benson KF, Person RE, Grimes HL, Horwitz MS.

Mol Cell Biol. 2009 Aug;29(16):4394-405. Epub 2009 Jun 8.PMID: 19506020 [PubMed - indexed for MEDLINE]Related articles

Coxsackievirus infection as an environmental factor in the etiology of type 1 diabetes.

Richer MJ, Horwitz MS.

Autoimmun Rev. 2009 Jun;8(7):611-5. Epub 2009 Feb 11. Review.PMID: 19393207 [PubMed - indexed for MEDLINE]Related articles

Toll-like receptor 3 signaling on macrophages is required for survival following coxsackievirus B4 infection.

Richer MJ, Lavallée DJ, Shanina I, Horwitz MS.

PLoS One. 2009;4(1):e4127. Epub 2009 Jan 5.PMID: 19122812 [PubMed - indexed for MEDLINE]Related articlesFree article

Lentivectors encoding immunosuppressive proteins genetically engineer pancreatic beta-cells to correct diabetes in allogeneic mice.

Kojaoghlanian T, Joseph A, Follenzi A, Zheng JH, Leiser M, Fleischer N, Horwitz MS, DiLorenzo TP, Goldstein H.

Gene Ther. 2009 Mar;16(3):340-8. Epub 2008 Dec 25.PMID: 19112449 [PubMed - in process]Related articles

Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean.

Grann VR, Ziv E, Joseph CK, Neugut AI, Wei Y, Jacobson JS, Horwitz MS, Bowman N, Beckmann K, Hershman DL.

Br J Haematol. 2008 Oct;143(2):288-93. Epub 2008 Aug 15.PMID: 18710383 [PubMed - indexed for MEDLINE]Related articlesFree article

Integrative analysis of RUNX1 downstream pathways and target genes.

Michaud J, Simpson KM, Escher R, Buchet-Poyau K, Beissbarth T, Carmichael C, Ritchie ME, Schütz F, Cannon P, Liu M, Shen X, Ito Y, Raskind WH, Horwitz MS, Osato M, Turner DR, Speed TP, Kavallaris M, Smyth GK, Scott HS.

BMC Genomics. 2008 Jul 31;9:363.PMID: 18671852 [PubMed - indexed for MEDLINE]Related articlesFree article

Neutropenia in 6 ethnic groups from the Caribbean and the U.S.

Grann VR, Bowman N, Joseph C, Wei Y, Horwitz MS, Jacobson JS, Santella RP, Hershman DL.

Cancer. 2008 Aug 15;113(4):854-60.PMID: 18543314 [PubMed - indexed for MEDLINE]Related articlesFree article

Viral infections in the pathogenesis of autoimmune diseases: focus on type 1 diabetes.

Richer MJ, Horwitz MS.

Front Biosci. 2008 May 1;13:4241-57. Review.PMID: 18508508 [PubMed - indexed for MEDLINE]Related articles

Regulatory T-cells protect from type 1 diabetes after induction by coxsackievirus infection in the context of transforming growth factor-beta.

Richer MJ, Straka N, Fang D, Shanina I, Horwitz MS.

Diabetes. 2008 May;57(5):1302-11. Epub 2008 Feb 11.PMID: 18268045 [PubMed - indexed for MEDLINE]Related articlesFree article

Phylogenetic fate mapping: theoretical and experimental studies applied to the development of mouse fibroblasts.

Salipante SJ, Thompson JM, Horwitz MS.

Genetics. 2008 Feb;178(2):967-77. Epub 2008 Feb 3.PMID: 18245843 [PubMed - indexed for MEDLINE]Related articlesFree article

Lymphadenopathy as the primary manifestation of malignant transformation in two patients with severe congenital neutropenia.

Gamper CJ, Takemoto CM, Schowinsky J, Borowitz MJ, Horwitz MS, Strouse JJ.

Pediatr Blood Cancer. 2008 May;50(5):1072-5.PMID: 18213714 [PubMed - indexed for MEDLINE]Related articles

Mutations in the zinc finger domain of IKK gamma block the activation of NF-kappa B and the induction of IL-2 in stimulated T lymphocytes.

Shifera AS, Horwitz MS.

Mol Immunol. 2008 Mar;45(6):1633-45. Epub 2008 Jan 22.PMID: 18207244 [PubMed - indexed for MEDLINE]Related articles

IKK gamma (NEMO) is involved in the coordination of the AP-1 and NF-kappa B pathways.

Shifera AS, Friedman JM, Horwitz MS.

Mol Cell Biochem. 2008 Mar;310(1-2):181-90. Epub 2007 Dec 16.PMID: 18080803 [PubMed - indexed for MEDLINE]Related articles

Chronic immunodeficiency in mice lacking RasGRP1 results in CD4 T cell immune activation and exhaustion.

Priatel JJ, Chen X, Zenewicz LA, Shen H, Harder KW, Horwitz MS, Teh HS.

J Immunol. 2007 Aug 15;179(4):2143-52.PMID: 17675473 [PubMed - indexed for MEDLINE]Related articlesFree article

Epigenetic regulation of protein-coding and microRNA genes by the Gfi1-interacting tumor suppressor PRDM5.

Duan Z, Person RE, Lee HH, Huang S, Donadieu J, Badolato R, Grimes HL, Papayannopoulou T, Horwitz MS.

Mol Cell Biol. 2007 Oct;27(19):6889-902. Epub 2007 Jul 16.PMID: 17636019 [PubMed - indexed for MEDLINE]Related articlesFree article

The clinical, immunohematological, and molecular study of Iranian patients with severe congenital neutropenia.

Rezaei N, Moin M, Pourpak Z, Ramyar A, Izadyar M, Chavoshzadeh Z, Sherkat R, Aghamohammadi A, Yeganeh M, Mahmoudi M, Mahjoub F, Germeshausen M, Grudzien M, Horwitz MS, Klein C, Farhoudi A.

J Clin Immunol. 2007 Sep;27(5):525-33. Epub 2007 Jun 21.PMID: 17587155 [PubMed - indexed for MEDLINE]Related articles

A phylogenetic approach to mapping cell fate.

Salipante SJ, Horwitz MS.

Curr Top Dev Biol. 2007;79:157-84. Review.PMID: 17498550 [PubMed - indexed for MEDLINE]Related articles

Double de novo mutations of ELA2 in cyclic and severe congenital neutropenia.

Salipante SJ, Benson KF, Luty J, Hadavi V, Kariminejad R, Kariminejad MH, Rezaei N, Horwitz MS.

Hum Mutat. 2007 Sep;28(9):874-81.PMID: 17436313 [PubMed - indexed for MEDLINE]Related articles

Prevention of hepatocyte allograft rejection in rats by transferring adenoviral early region 3 genes into donor cells.

Mashalova EV, Guha C, Roy-Chowdhury N, Liu L, Fox IJ, Roy-Chowdhury J, Horwitz MS.

Hepatology. 2007 Mar;45(3):755-66.PMID: 17326202 [PubMed - indexed for MEDLINE]Related articles

Transforming growth factor-beta inhibits coxsackievirus-mediated autoimmune myocarditis.

Horwitz MS, Knudsen M, Ilic A, Fine C, Sarvetnick N.

Viral Immunol. 2006 Winter;19(4):722-33.PMID: 17201667 [PubMed - indexed for MEDLINE]Related articles

Further evidence for a pseudoautosomal gene for Hodgkin's lymphoma: Reply to 'The familial risk of Hodgkin's lymphoma ranks among the highest in the Swedish Family-Cancer Database' by Altieri A and Hemminki K.

Horwitz MS, Mealiffe ME.

Leukemia. 2007 Feb;21(2):351. Epub 2006 Dec 7. No abstract available. PMID: 17151699 [PubMed - indexed for MEDLINE]Related articles

Neutrophil elastase in cyclic and severe congenital neutropenia.

Horwitz MS, Duan Z, Korkmaz B, Lee HH, Mealiffe ME, Salipante SJ.

Blood. 2007 Mar 1;109(5):1817-24. Epub 2006 Oct 19. Review.PMID: 17053055 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenovirus RID complex enhances degradation of internalized tumour necrosis factor receptor 1 without affecting its rate of endocytosis.

Chin YR, Horwitz MS.

J Gen Virol. 2006 Nov;87(Pt 11):3161-7.PMID: 17030848 [PubMed - indexed for MEDLINE]Related articlesFree article

Toll-like receptor 4-induced cytokine production circumvents protection conferred by TGF-beta in coxsackievirus-mediated autoimmune myocarditis.

Richer MJ, Fang D, Shanina I, Horwitz MS.

Clin Immunol. 2006 Dec;121(3):339-49. Epub 2006 Sep 11.PMID: 16963319 [PubMed - indexed for MEDLINE]Related articles

Adenovirus RIDalphabeta complex inhibits lipopolysaccharide signaling without altering TLR4 cell surface expression.

Delgado-Lopez F, Horwitz MS.

J Virol. 2006 Jul;80(13):6378-86.PMID: 16775326 [PubMed - indexed for MEDLINE]Related articlesFree article

Phylogenetic fate mapping.

Salipante SJ, Horwitz MS.

Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5448-53. Epub 2006 Mar 28.PMID: 16569691 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor necrosis factor-alpha and CD40L modulate cell surface morphology and induce aggregation in Ramos Burkitt's lymphoma cells.

Laskov R, Berger N, Scharff MD, Horwitz MS.

Leuk Lymphoma. 2006 Mar;47(3):507-19.PMID: 16523591 [PubMed - indexed for MEDLINE]Related articles

Differential effects of tumor necrosis factor-alpha and CD40L on NF-kappa B inhibitory proteins I kappa B alpha, beta and epsilon and on the induction of the Jun amino-terminal kinase pathway in Ramos Burkitt lymphoma cells.

Laskov R, Berger N, Horwitz MS.

Eur Cytokine Netw. 2005 Dec;16(4):267-76.PMID: 16464740 [PubMed - indexed for MEDLINE]Related articles

Mechanism for removal of tumor necrosis factor receptor 1 from the cell surface by the adenovirus RIDalpha/beta complex.

Chin YR, Horwitz MS.

J Virol. 2005 Nov;79(21):13606-17.PMID: 16227281 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of antigen specific peripheral humoral tolerance to cardiac myosin does not prevent CB3-mediated autoimmune myocarditis.

Horwitz MS, Ilic A, Fine C, Sarvetnick N.

J Autoimmun. 2005 Sep;25(2):102-11. Epub 2005 Jul 11.PMID: 16011890 [PubMed - indexed for MEDLINE]Related articles

Adenovirus early region 3 transgenes expressed in beta cells prevent autoimmune diabetes in nonobese diabetic mice: effects of deleting the adenovirus death protein 11.6K.

Pierce MA, Svetlanov A, Horwitz MS, Serreze DV.

J Virol. 2005 Jan;79(1):619-21.PMID: 15596856 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of tumor necrosis factor (TNF) signal transduction by the adenovirus group C RID complex involves downregulation of surface levels of TNF receptor 1.

Fessler SP, Chin YR, Horwitz MS.

J Virol. 2004 Dec;78(23):13113-21.PMID: 15542663 [PubMed - indexed for MEDLINE]Related articlesFree article

Terminal deoxynucleotidyltransferase deficiency decreases autoimmune disease in diabetes-prone nonobese diabetic mice and lupus-prone MRL-Fas(lpr) mice.

Robey IF, Peterson M, Horwitz MS, Kono DH, Stratmann T, Theofilopoulos AN, Sarvetnick N, Teyton L, Feeney AJ.

J Immunol. 2004 Apr 1;172(7):4624-9.PMID: 15034081 [PubMed - indexed for MEDLINE]Related articlesFree article

Coxsackieviral-mediated diabetes: induction requires antigen-presenting cells and is accompanied by phagocytosis of beta cells.

Horwitz MS, Ilic A, Fine C, Balasa B, Sarvetnick N.

Clin Immunol. 2004 Feb;110(2):134-44.PMID: 15003810 [PubMed - indexed for MEDLINE]Related articles

Function of adenovirus E3 proteins and their interactions with immunoregulatory cell proteins.

Horwitz MS.

J Gene Med. 2004 Feb;6 Suppl 1:S172-83. Review.PMID: 14978760 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of E3 modulation of immune and inflammatory responses.

Fessler SP, Delgado-Lopez F, Horwitz MS.

Curr Top Microbiol Immunol. 2004;273:113-35. Review.PMID: 14674600 [PubMed - indexed for MEDLINE]Related articles

Coxsackievirus-mediated hyperglycemia is enhanced by reinfection and this occurs independent of T cells.

Horwitz MS, Ilic A, Fine C, Rodriguez E, Sarvetnick N.

Virology. 2003 Sep 30;314(2):510-20.PMID: 14554080 [PubMed - indexed for MEDLINE]Related articles

The impact of adenovirus infection on the immunocompromised host.

Kojaoghlanian T, Flomenberg P, Horwitz MS.

Rev Med Virol. 2003 May-Jun;13(3):155-71. Review.PMID: 12740831 [PubMed - indexed for MEDLINE]Related articles

Inhibition of chemokine expression by adenovirus early region three (E3) genes.

Lesokhin AM, Delgado-Lopez F, Horwitz MS.

J Virol. 2002 Aug;76(16):8236-43.PMID: 12134029 [PubMed - indexed for MEDLINE]Related articlesFree article

A non-immunogenic adenoviral vector, coexpressing CTLA4Ig and bilirubin-uridine-diphosphoglucuronateglucuronosyltransferase permits long-term, repeatable transgene expression in the Gunn rat model of Crigler-Najjar syndrome.

Thummala NR, Ghosh SS, Lee SW, Reddy B, Davidson A, Horwitz MS, Chowdhury JR, Chowdhury NR.

Gene Ther. 2002 Aug;9(15):981-90.PMID: 12101428 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of tumor necrosis factor alpha-induced NF-kappa B activation by the adenovirus E3-10.4/14.5K complex.

Friedman JM, Horwitz MS.

J Virol. 2002 Jun;76(11):5515-21.PMID: 11991979 [PubMed - indexed for MEDLINE]Related articlesFree article

Evolution of adenoviruses as gene therapy vectors.

Roy-Chowdhury J, Horwitz MS.

Mol Ther. 2002 Apr;5(4):340-4. No abstract available. PMID: 11945059 [PubMed - indexed for MEDLINE]Related articlesFree article

Presented antigen from damaged pancreatic beta cells activates autoreactive T cells in virus-mediated autoimmune diabetes.

Horwitz MS, Ilic A, Fine C, Rodriguez E, Sarvetnick N.

J Clin Invest. 2002 Jan;109(1):79-87.PMID: 11781353 [PubMed - indexed for MEDLINE]Related articlesFree article

Sites on FIP-3 (NEMO/IKKgamma) essential for its phosphorylation and NF-kappaB modulating activity.

Tarassishin L, Horwitz MS.

Biochem Biophys Res Commun. 2001 Jul 13;285(2):555-60.PMID: 11444880 [PubMed - indexed for MEDLINE]Related articles