PubMed

Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat.

Lacraz G, Giroix MH, Kassis N, Coulaud J, Galinier A, Noll C, Cornut M, Schmidlin F, Paul JL, Janel N, Irminger JC, Kergoat M, Portha B, Donath MY, Ehses JA, Homo-Delarche F.

PLoS One. 2009 Sep 9;4(9):e6963.PMID: 19742300 [PubMed - in process]Related articlesFree article

IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat.

Ehses JA, Lacraz G, Giroix MH, Schmidlin F, Coulaud J, Kassis N, Irminger JC, Kergoat M, Portha B, Homo-Delarche F, Donath MY.

Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13998-4003. Epub 2009 Jul 30.PMID: 19666548 [PubMed - indexed for MEDLINE]Related articles

Diabetic beta-cells can achieve self-protection against oxidative stress through an adaptive up-regulation of their antioxidant defenses.

Lacraz G, Figeac F, Movassat J, Kassis N, Coulaud J, Galinier A, Leloup C, Bailbé D, Homo-Delarche F, Portha B.

PLoS One. 2009 Aug 5;4(8):e6500.PMID: 19654863 [PubMed - in process]Related articlesFree article

Brain alterations in autoimmune and pharmacological models of diabetes mellitus: focus on hypothalamic-pituitary-adrenocortical axis disturbances.

Beauquis J, Homo-Delarche F, Revsin Y, De Nicola AF, Saravia F.

Neuroimmunomodulation. 2008;15(1):61-7. Epub 2008 Jul 29. Review.PMID: 18667801 [PubMed - indexed for MEDLINE]Related articles

The GK rat beta-cell: a prototype for the diseased human beta-cell in type 2 diabetes?

Portha B, Lacraz G, Kergoat M, Homo-Delarche F, Giroix MH, Bailbé D, Gangnerau MN, Dolz M, Tourrel-Cuzin C, Movassat J.

Mol Cell Endocrinol. 2009 Jan 15;297(1-2):73-85. Epub 2008 Jul 1. Review.PMID: 18640239 [PubMed - indexed for MEDLINE]Related articles

Prominently decreased hippocampal neurogenesis in a spontaneous model of type 1 diabetes, the nonobese diabetic mouse.

Beauquis J, Saravia F, Coulaud J, Roig P, Dardenne M, Homo-Delarche F, De Nicola A.

Exp Neurol. 2008 Apr;210(2):359-67. Epub 2007 Nov 29.PMID: 18190910 [PubMed - indexed for MEDLINE]Related articles

Bromocriptine-induced hyperglycemia in nonobese diabetic mice: kinetics and mechanisms of action.

Durant S, Coulaud J, Homo-Delarche F.

Rev Diabet Stud. 2007 Fall;4(3):185-94. Epub 2007 Nov 10.PMID: 18084676 [PubMed - in process]Related articlesFree article

Marked genetic differences in the regulation of blood glucose under immune and restraint stress in mice reveals a wide range of corticosensitivity.

Harizi H, Homo-Delarche F, Amrani A, Coulaud J, Mormède P.

J Neuroimmunol. 2007 Sep;189(1-2):59-68. Epub 2007 Jul 20.PMID: 17658621 [PubMed - indexed for MEDLINE]Related articles

Increased number of islet-associated macrophages in type 2 diabetes.

Ehses JA, Perren A, Eppler E, Ribaux P, Pospisilik JA, Maor-Cahn R, Gueripel X, Ellingsgaard H, Schneider MK, Biollaz G, Fontana A, Reinecke M, Homo-Delarche F, Donath MY.

Diabetes. 2007 Sep;56(9):2356-70. Epub 2007 Jun 19.PMID: 17579207 [PubMed - indexed for MEDLINE]Related articlesFree article

Tolerance induction and endogenous regeneration of pancreatic beta-cells in established autoimmune diabetes.

Sia C, Homo-Delarche F.

Rev Diabet Stud. 2004 Winter;1(4):198-206. Epub 2005 Feb 10.PMID: 17491705 [PubMed]Related articlesFree article

Increased transcriptional preproinsulin II beta-cell activity in neonatal nonobese diabetic mice: in situ hybridization analysis.

Throsby M, Coulaud J, Durant S, Homo-Delarche F.

Rev Diabet Stud. 2005 Summer;2(2):75-83. Epub 2005 Aug 10.PMID: 17491682 [PubMed]Related articlesFree article

Hippocampal neuropathology of diabetes mellitus is relieved by estrogen treatment.

Saravia FE, Beauquis J, Revsin Y, Homo-Delarche F, de Kloet ER, De Nicola AF.

Cell Mol Neurobiol. 2006 Jul-Aug;26(4-6):943-57. Epub 2006 Jun 29.PMID: 16807785 [PubMed - indexed for MEDLINE]Related articles

Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK rat.

Homo-Delarche F, Calderari S, Irminger JC, Gangnerau MN, Coulaud J, Rickenbach K, Dolz M, Halban P, Portha B, Serradas P.

Diabetes. 2006 Jun;55(6):1625-33. Erratum in: Diabetes. 2006 Sep;55(9):2665. PMID: 16731824 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced hippocampal neurogenesis and number of hilar neurones in streptozotocin-induced diabetic mice: reversion by antidepressant treatment.

Beauquis J, Roig P, Homo-Delarche F, De Nicola A, Saravia F.

Eur J Neurosci. 2006 Mar;23(6):1539-46.PMID: 16553617 [PubMed - indexed for MEDLINE]Related articles

Neuronal and astroglial alterations in the hippocampus of a mouse model for type 1 diabetes.

Revsin Y, Saravia F, Roig P, Lima A, de Kloet ER, Homo-Delarche F, De Nicola AF.

Brain Res. 2005 Mar 15;1038(1):22-31.PMID: 15748869 [PubMed - indexed for MEDLINE]Related articles

Extracellular matrix distribution and islet morphology in the early postnatal pancreas: anomalies in the non-obese diabetic mouse.

Geutskens SB, Homo-Delarche F, Pleau JM, Durant S, Drexhage HA, Savino W.

Cell Tissue Res. 2004 Dec;318(3):579-89. Epub 2004 Oct 5.PMID: 15480796 [PubMed - indexed for MEDLINE]Related articles

Oestradiol restores cell proliferation in dentate gyrus and subventricular zone of streptozotocin-diabetic mice.

Saravia F, Revsin Y, Lux-Lantos V, Beauquis J, Homo-Delarche F, De Nicola AF.

J Neuroendocrinol. 2004 Aug;16(8):704-10.PMID: 15271063 [PubMed - indexed for MEDLINE]Related articles

Neuroendocrine immuno-ontogeny of the pathogenesis of autoimmune disease in the nonobese diabetic (NOD) mouse.

Homo-Delarche F.

ILAR J. 2004;45(3):237-58. Review.PMID: 15229372 [PubMed - indexed for MEDLINE]Related articlesFree article

Immune cells, pancreas development, regeneration and type 1 diabetes.

Homo-Delarche F, Drexhage HA.

Trends Immunol. 2004 May;25(5):222-9. Review. No abstract available. PMID: 15099561 [PubMed - indexed for MEDLINE]Related articles

Is innervation an early target in autoimmune diabetes?

Saravia F, Homo-Delarche F.

Trends Immunol. 2003 Nov;24(11):574-9. Review.PMID: 14596878 [PubMed - indexed for MEDLINE]Related articles

Nonobese diabetic (NOD) mouse dendritic cells stimulate insulin secretion by prediabetic islets.

Durant S, Alves V, Coulaud J, Homo-Delarche F.

Autoimmunity. 2002 Nov;35(7):449-55.PMID: 12685873 [PubMed - indexed for MEDLINE]Related articles

Proapoptosis and antiapoptosis-related molecules during postnatal pancreas development in control and nonobese diabetic mice: relationship with innervation.

Durant S, Geutskens S, Van Blokland SC, Coulaud J, Alves V, Pleau JM, Versnel M, Drexhage HA, Homo-Delarche F.

Lab Invest. 2003 Feb;83(2):227-39.PMID: 12594237 [PubMed - indexed for MEDLINE]Related articles

Apoptosis and apoptosis-related molecules in the submandibular gland of the nonobese diabetic mouse model for Sjögren's syndrome: limited role for apoptosis in the development of sialoadenitis.

Van Blokland SC, Van Helden-Meeuwsen CG, Wierenga-Wolf AF, Tielemans D, Drexhage HA, Van De Merwe JP, Homo-Delarche F, Versnel MA.

Lab Invest. 2003 Jan;83(1):3-11.PMID: 12533681 [PubMed - indexed for MEDLINE]Related articles

Increased astrocyte reactivity in the hippocampus of murine models of type 1 diabetes: the nonobese diabetic (NOD) and streptozotocin-treated mice.

Saravia FE, Revsin Y, Gonzalez Deniselle MC, Gonzalez SL, Roig P, Lima A, Homo-Delarche F, De Nicola AF.

Brain Res. 2002 Dec 13;957(2):345-53.PMID: 12445977 [PubMed - indexed for MEDLINE]Related articles

Islet abnormalities in the pathogenesis of autoimmune diabetes.

Rosmalen JG, Leenen PJ, Pelegri C, Drexhage HA, Homo-Delarche F.

Trends Endocrinol Metab. 2002 Jul;13(5):209-14. Review.PMID: 12185667 [PubMed - indexed for MEDLINE]Related articles

Abnormalities in dendritic cell and macrophage accumulation in the pancreas of nonobese diabetic (NOD) mice during the early neonatal period.

Charré S, Rosmalen JG, Pelegri C, Alves V, Leenen PJ, Drexhage HA, Homo-Delarche F.

Histol Histopathol. 2002 Apr;17(2):393-401.PMID: 11962743 [PubMed - indexed for MEDLINE]Related articles

Abnormal organogenesis in salivary gland development may initiate adult onset of autoimmune exocrinopathy.

Cha S, van Blockland SC, Versnel MA, Homo-Delarche F, Nagashima H, Brayer J, Peck AB, Humphreys-Beher MG.

Exp Clin Immunogenet. 2001;18(3):143-60.PMID: 11549844 [PubMed - indexed for MEDLINE]Related articles

Islet endocrine-cell behavior from birth onward in mice with the nonobese diabetic genetic background.

Pelegri C, Rosmalen JG, Durant S, Throsby M, Alvès V, Coulaud J, Esling A, Pléau JM, Drexhage HA, Homo-Delarche F.

Mol Med. 2001 May;7(5):311-9.PMID: 11474577 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes increases the expression of hypothalamic neuropeptides in a spontaneous model of type I diabetes, the nonobese diabetic (NOD) mouse.

Saravia FE, Gonzalez SL, Roig P, Alves V, Homo-Delarche F, De Nicola AF.

Cell Mol Neurobiol. 2001 Feb;21(1):15-27.PMID: 11440195 [PubMed - indexed for MEDLINE]Related articles

Pancreatic hormone and glutamic acid decarboxylase expression in the mouse thymus: a real-time PCR study.

Pléau JM, Esling A, Geutkens S, Dardenne M, Homo-Delarche F.

Biochem Biophys Res Commun. 2001 May 18;283(4):843-8.PMID: 11350061 [PubMed - indexed for MEDLINE]Related articles

Is pancreas development abnormal in the non-obese diabetic mouse, a spontaneous model of type I diabetes?

Homo-Delarche F.

Braz J Med Biol Res. 2001 Apr;34(4):437-47. Review.PMID: 11285454 [PubMed - indexed for MEDLINE]Related articlesFree article

Sex steroids influence pancreatic islet hypertrophy and subsequent autoimmune infiltration in nonobese diabetic (NOD) and NODscid mice.

Rosmalen JG, Pigmans MJ, Kersseboom R, Drexhage HA, Leenen PJ, Homo-Delarche F.

Lab Invest. 2001 Feb;81(2):231-9.PMID: 11232645 [PubMed - indexed for MEDLINE]Related articles

Islet abnormalities associated with an early influx of dendritic cells and macrophages in NOD and NODscid mice.

Rosmalen JG, Homo-Delarche F, Durant S, Kap M, Leenen PJ, Drexhage HA.

Lab Invest. 2000 May;80(5):769-77.PMID: 10830787 [PubMed - indexed for MEDLINE]Related articles

Increased sensitivity of prediabetic nonobese diabetic mouse to the behavioral effects of IL-1.

Bluth, Jafarian-Tehrani M, Michaud B, Haour F, Dantzer R, Homo-Delarche F.

Brain Behav Immun. 1999 Dec;13(4):303-14.PMID: 10600218 [PubMed - indexed for MEDLINE]Related articles

Basal concentrations of various steroids in the nonobese diabetic (NOD) mouse and effect of immobilization stress.

Durant S, Christeff N, Coulaud J, Nunez EA, Dardenne M, Homo-Delarche F.

Autoimmunity. 1998;28(4):249-58.PMID: 9892507 [PubMed - indexed for MEDLINE]Related articles

Thymic expression of the pancreatic endocrine hormones.

Throsby M, Pleau J, Dardenne M, Homo-Delarche F.

Neuroimmunomodulation. 1999 Jan-Apr;6(1-2):108-14. Review.PMID: 9876241 [PubMed - indexed for MEDLINE]Related articles

Pancreatic hormone expression in the murine thymus: localization in dendritic cells and macrophages.

Throsby M, Homo-Delarche F, Chevenne D, Goya R, Dardenne M, Pleau JM.

Endocrinology. 1998 May;139(5):2399-406.PMID: 9564851 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell behaviour during the prediabetic stage. Part II. Non-insulin-dependent and insulin-dependent diabetes mellitus.

Homo-Delarche F.

Diabetes Metab. 1997 Dec;23(6):473-505. Review.PMID: 9496555 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose homeostasis in the nonobese diabetic mouse at the prediabetic stage.

Amrani A, Durant S, Throsby M, Coulaud J, Dardenne M, Homo-Delarche F.

Endocrinology. 1998 Mar;139(3):1115-24.PMID: 9492045 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell behavior during the prediabetic stage. Part I. Beta-cell pathophysiology.

Homo-Delarche F.

Diabetes Metab. 1997 Jun;23(3):181-94. Review.PMID: 9233994 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoimmune diabetes: the role of the islets of Langerhans.

Homo-Delarche F, Boitard C.

Immunol Today. 1996 Oct;17(10):456-60. Review. No abstract available. PMID: 8908809 [PubMed - indexed for MEDLINE]Related articles

Localization of gamma-aminobutyric acid and glutamic acid decarboxylase in the pancreas of the nonobese diabetic mouse.

Saravia-Fernandez F, Faveeuw C, Blasquez-Bulant C, Tappaz M, Throsby M, Pelletier G, Vaudry H, Dardenne M, Homo-Delarche F.

Endocrinology. 1996 Aug;137(8):3497-506.PMID: 8754779 [PubMed - indexed for MEDLINE]Related articles

Effect of prophylactic insulin treatment on the number of ER-MP23+ macrophages in the pancreas of NOD mice. Is the prevention of diabetes based on beta-cell rest?

Jansen A, Rosmalen JG, Homo-Delarche F, Dardenne M, Drexhage HA.

J Autoimmun. 1996 Jun;9(3):341-8.PMID: 8816969 [PubMed - indexed for MEDLINE]Related articles

Environmental and experimental procedures leading to variations in the incidence of diabetes in the nonobese diabetic (NOD) mouse.

Saravia-Fernandez F, Durant S, el Hasnaoui A, Dardenne M, Homo-Delarche F.

Autoimmunity. 1996;24(2):113-21.PMID: 8986323 [PubMed - indexed for MEDLINE]Related articles

Interleukin-1 effect on glycemia in the non-obese diabetic mouse at the pre-diabetic stage.

Amrani A, Jafarian-Tehrani M, Mormède P, Durant S, Pleau JM, Haour F, Dardenne M, Homo-Delarche F.

J Endocrinol. 1996 Jan;148(1):139-48.PMID: 8568461 [PubMed - indexed for MEDLINE]Related articles

Attempts to pharmacologically modulate prolactin levels and type 1 autoimmune diabetes in the non-obese diabetic (NOD) mouse.

Durant S, Alves V, Coulaud J, El Hasnaoui A, Dardenne M, Homo-Delarche F.

J Autoimmun. 1995 Dec;8(6):875-85.PMID: 8824712 [PubMed - indexed for MEDLINE]Related articles

Prevention of autoimmune diabetes in nonobese diabetic female mice by treatment with recombinant glutamic acid decarboxylase (GAD 65).

Pleau JM, Fernandez-Saravia F, Esling A, Homo-Delarche F, Dardenne M.

Clin Immunol Immunopathol. 1995 Jul;76(1 Pt 1):90-5.PMID: 7606872 [PubMed - indexed for MEDLINE]Related articles

[Stress and premature menopause]

Letur-Könirsch H, Raoul-Duval A, Cabau A, Bomsel-Helmreich O, al Mufti W, Homo-Delarche F.

C R Acad Sci III. 1995 Jun;318(6):691-8. French. PMID: 7671013 [PubMed - indexed for MEDLINE]Related articles

PCR analysis of interleukin-1 receptor gene in the nonobese diabetic mouse.

Amrani A, Homo-Delarche F, Dardenne M, Pléau JM.

Eur Cytokine Netw. 1995 Mar-Apr;6(2):103-7.PMID: 7578987 [PubMed - indexed for MEDLINE]Related articles

Localization and characterization of interleukin-1 receptors in the islets of Langerhans from control and nonobese diabetic mice.

Jafarian-Tehrani M, Amrani A, Homo-Delarche F, Marquette C, Dardenne M, Haour F.

Endocrinology. 1995 Feb;136(2):609-13.PMID: 7835294 [PubMed - indexed for MEDLINE]Related articles