PubMed

Food-restriction in obese dyslipidaemic diabetic mice partially restores basal contractility but not contractile reserve.

Van den Bergh A, Vangheluwe P, Vanderper A, Carmeliet P, Wuytack F, Janssens S, Flameng W, Holvoet P, Herijgers P.

Eur J Heart Fail. 2009 Dec;11(12):1118-1125.PMID: 19926597 [PubMed - as supplied by publisher]Related articles

Oxidized LDL and the metabolic syndrome.

Holvoet P, De Keyzer D, Jacobs DR.

Future Lipidol. 2008 Dec;3(6):637-649.PMID: 19802339 [PubMed]Related articlesFree article

Increased PAFAH and Oxidized Lipids Are Associated With Inflammation and Atherosclerosis in Hypercholesterolemic Pigs.

De Keyzer D, Karabina SA, Wei W, Geeraert B, Stengel D, Marsillach J, Camps J, Holvoet P, Ninio E.

Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2041-2046. Epub 2009 Oct 1.PMID: 19797705 [PubMed - as supplied by publisher]Related articles

Association between oxidized LDL, obesity and type 2 diabetes in a population-based cohort, the health, aging and body composition study.

Njajou OT, Kanaya AM, Holvoet P, Connelly S, Strotmeyer ES, Harris TB, Cummings SR, Hsueh WC; Health ABC Study.

Diabetes Metab Res Rev. 2009 Nov;25(8):733-9.PMID: 19780064 [PubMed - in process]Related articles

Obesity-asthma association: is it explained by systemic oxidant stress?

Sood A, Qualls C, Arynchyn A, Beckett WS, Gross MD, Steffes MW, Smith LJ, Holvoet P, Thyagarajan B, Jacobs DR Jr.

Chest. 2009 Oct;136(4):1055-62. Epub 2009 Jul 10.PMID: 19592473 [PubMed - indexed for MEDLINE]Related articles

Oxidative stress and insulin resistance: the coronary artery risk development in young adults study.

Park K, Gross M, Lee DH, Holvoet P, Himes JH, Shikany JM, Jacobs DR Jr.

Diabetes Care. 2009 Jul;32(7):1302-7. Epub 2009 Apr 23.PMID: 19389821 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship of lipoprotein-associated phospholipase A2 and oxidized low-density lipoprotein in carotid atherosclerosis.

Vickers KC, Maguire CT, Wolfert R, Burns AR, Reardon M, Geis R, Holvoet P, Morrisett JD.

J Lipid Res. 2009 Apr 9. [Epub ahead of print]PMID: 19359705 [PubMed - as supplied by publisher]Related articlesFree article

Influence of exercise at lower and higher intensity on blood pressure and cardiovascular risk factors at older age.

Cornelissen VA, Arnout J, Holvoet P, Fagard RH.

J Hypertens. 2009 Apr;27(4):753-62.PMID: 19300110 [PubMed - indexed for MEDLINE]Related articles

Thrombospondin-1 deficiency accelerates atherosclerotic plaque maturation in ApoE-/- mice.

Moura R, Tjwa M, Vandervoort P, Van Kerckhoven S, Holvoet P, Hoylaerts MF.

Circ Res. 2008 Nov 7;103(10):1181-9. Epub 2008 Sep 25.PMID: 18818405 [PubMed - indexed for MEDLINE]Related articlesFree article

Relations between metabolic syndrome, oxidative stress and inflammation and cardiovascular disease.

Holvoet P.

Verh K Acad Geneeskd Belg. 2008;70(3):193-219. Review.PMID: 18669160 [PubMed - indexed for MEDLINE]Related articles

Angio-associated migratory cell protein and smooth muscle cell migration in development of restenosis and atherosclerosis.

Holvoet P, Sinnaeve P.

J Am Coll Cardiol. 2008 Jul 22;52(4):312-4. No abstract available. PMID: 18634988 [PubMed - indexed for MEDLINE]Related articles

Association between circulating oxidized low-density lipoprotein and incidence of the metabolic syndrome.

Holvoet P, Lee DH, Steffes M, Gross M, Jacobs DR Jr.

JAMA. 2008 May 21;299(19):2287-93.PMID: 18492970 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosuvastatin increases vascular endothelial PPARgamma expression and corrects blood pressure variability in obese dyslipidaemic mice.

Desjardins F, Sekkali B, Verreth W, Pelat M, De Keyzer D, Mertens A, Smith G, Herregods MC, Holvoet P, Balligand JL.

Eur Heart J. 2008 Jan;29(1):128-37. Epub 2007 Dec 6.PMID: 18063594 [PubMed - indexed for MEDLINE]Related articlesFree article

Paraoxonase 1 gene transfer lowers vascular oxidative stress and improves vasomotor function in apolipoprotein E-deficient mice with pre-existing atherosclerosis.

Guns PJ, Van Assche T, Verreth W, Fransen P, Mackness B, Mackness M, Holvoet P, Bult H.

Br J Pharmacol. 2008 Feb;153(3):508-16. Epub 2007 Dec 3.PMID: 18059326 [PubMed - indexed for MEDLINE]Related articlesFree article

Pioglitazone improves myocardial blood flow and glucose utilization in nondiabetic patients with combined hyperlipidemia: a randomized, double-blind, placebo-controlled study.

Naoumova RP, Kindler H, Leccisotti L, Mongillo M, Khan MT, Neuwirth C, Seed M, Holvoet P, Betteridge J, Camici PG.

J Am Coll Cardiol. 2007 Nov 20;50(21):2051-8. Epub 2007 Nov 5.PMID: 18021872 [PubMed - indexed for MEDLINE]Related articles

Dyslipidaemia in type II diabetic mice does not aggravate contractile impairment but increases ventricular stiffness.

Van den Bergh A, Vanderper A, Vangheluwe P, Desjardins F, Nevelsteen I, Verreth W, Wuytack F, Holvoet P, Flameng W, Balligand JL, Herijgers P.

Cardiovasc Res. 2008 Jan 15;77(2):371-9. Epub 2007 Aug 14.PMID: 18006491 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidized low-density lipoprotein-induced expression of ABCA1 in blood monocytes precedes coronary atherosclerosis and is associated with plaque complexity in hypercholesterolemic pigs.

Geeraert B, De Keyzer D, Davey PC, Crombé F, Benhabilès N, Holvoet P.

J Thromb Haemost. 2007 Dec;5(12):2529-36. Epub 2007 Oct 8.PMID: 17922810 [PubMed - indexed for MEDLINE]Related articles

Defective leptin/leptin receptor signaling improves regulatory T cell immune response and protects mice from atherosclerosis.

Taleb S, Herbin O, Ait-Oufella H, Verreth W, Gourdy P, Barateau V, Merval R, Esposito B, Clément K, Holvoet P, Tedgui A, Mallat Z.

Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2691-8. Epub 2007 Aug 9.PMID: 17690315 [PubMed - indexed for MEDLINE]Related articlesFree article

Pioglitazone added to conventional lipid-lowering treatment in familial combined hyperlipidaemia improves parameters of metabolic control: relation to liver, muscle and regional body fat content.

Thomas EL, Potter E, Tosi I, Fitzpatrick J, Hamilton G, Amber V, Hughes R, North C, Holvoet P, Seed M, Betteridge DJ, Bell JD, Naoumova RP.

Atherosclerosis. 2007 Nov;195(1):e181-90. Epub 2007 May 7.PMID: 17482623 [PubMed - indexed for MEDLINE]Related articles

The complex link between oxidised low-density lipoprotein and unstable angina.

Niccoli G, Mongiardo R, Lanza GA, Ricco A, Burzotta F, Trani C, Mazzari MA, Liuzzo G, Lombardo A, Rebuzzi AG, Holvoet P, Crea F.

J Cardiovasc Med (Hagerstown). 2007 May;8(5):387-91.PMID: 17443110 [PubMed - indexed for MEDLINE]Related articles

Rosuvastatin restores superoxide dismutase expression and inhibits accumulation of oxidized LDL in the aortic arch of obese dyslipidemic mice.

Verreth W, De Keyzer D, Davey PC, Geeraert B, Mertens A, Herregods MC, Smith G, Desjardins F, Balligand JL, Holvoet P.

Br J Pharmacol. 2007 Jun;151(3):347-55. Epub 2007 Mar 26.PMID: 17384667 [PubMed - indexed for MEDLINE]Related articlesFree article

Gelatinolytic activity in atherosclerotic plaques is highly localized and is associated with both macrophages and smooth muscle cells in vivo.

Segers D, Helderman F, Cheng C, van Damme LC, Tempel D, Boersma E, Serruys PW, de Crom R, van der Steen AF, Holvoet P, Krams R.

Circulation. 2007 Feb 6;115(5):609-16. Epub 2007 Jan 22.PMID: 17242283 [PubMed - indexed for MEDLINE]Related articlesFree article

The importance of catch-up growth after early malnutrition for the programming of obesity in male rat.

Bieswal F, Ahn MT, Reusens B, Holvoet P, Raes M, Rees WD, Remacle C.

Obesity (Silver Spring). 2006 Aug;14(8):1330-43.PMID: 16988075 [PubMed - indexed for MEDLINE]Related articles

The relationship between oxidized LDL and other cardiovascular risk factors and subclinical CVD in different ethnic groups: the Multi-Ethnic Study of Atherosclerosis (MESA).

Holvoet P, Jenny NS, Schreiner PJ, Tracy RP, Jacobs DR; Multi-Ethnic Study of Atherosclerosis.

Atherosclerosis. 2007 Sep;194(1):245-52. Epub 2006 Sep 18.PMID: 16982059 [PubMed - indexed for MEDLINE]Related articles

Application of NIRS in mice: a study comparing the oxygenation of cerebral blood and main tissue oxygenation of mice and rat.

De Visscher G, Verreth W, Blockx H, van Rossem K, Holvoet P, Flameng W.

Adv Exp Med Biol. 2006;578:197-202. No abstract available. PMID: 16927693 [PubMed - indexed for MEDLINE]Related articles

Obesity, the metabolic syndrome, and oxidized LDL.

Holvoet P.

Am J Clin Nutr. 2006 Jun;83(6):1438; author reply 1438-9. No abstract available. PMID: 16762956 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidized low-density lipoprotein correlates positively with toll-like receptor 2 and interferon regulatory factor-1 and inversely with superoxide dismutase-1 expression: studies in hypercholesterolemic swine and THP-1 cells.

Holvoet P, Davey PC, De Keyzer D, Doukouré M, Deridder E, Bochaton-Piallat ML, Gabbiani G, Beaufort E, Bishay K, Andrieux N, Benhabilès N, Marguerie G.

Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1558-65. Epub 2006 May 11.PMID: 16690872 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic syndrome and the risk of cardiovascular disease in older adults.

Butler J, Rodondi N, Zhu Y, Figaro K, Fazio S, Vaughan DE, Satterfield S, Newman AB, Goodpaster B, Bauer DC, Holvoet P, Harris TB, de Rekeneire N, Rubin S, Ding J, Kritchevsky SB; Health ABC Study.

J Am Coll Cardiol. 2006 Apr 18;47(8):1595-602. Epub 2006 Mar 27.PMID: 16630996 [PubMed - indexed for MEDLINE]Related articles

Human paraoxonase-1 overexpression inhibits atherosclerosis in a mouse model of metabolic syndrome.

Mackness B, Quarck R, Verreth W, Mackness M, Holvoet P.

Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1545-50. Epub 2006 Apr 20.PMID: 16627808 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidized LDL and the metabolic syndrome.

Holvoet P, Harris TB, Tracy RP, Kritchevsky SB.

Arterioscler Thromb Vasc Biol. 2006 Apr;26(4):e31; author reply e31-2. No abstract available. PMID: 16556859 [PubMed - indexed for MEDLINE]Related articlesFree article

CREB activation induced by mitochondrial dysfunction triggers triglyceride accumulation in 3T3-L1 preadipocytes.

Vankoningsloo S, De Pauw A, Houbion A, Tejerina S, Demazy C, de Longueville F, Bertholet V, Renard P, Remacle J, Holvoet P, Raes M, Arnould T.

J Cell Sci. 2006 Apr 1;119(Pt 7):1266-82. Epub 2006 Mar 14.PMID: 16537646 [PubMed - indexed for MEDLINE]Related articlesFree article

Analytical performance and diagnostic accuracy of immunometric assays for the measurement of circulating oxidized LDL.

Holvoet P, Macy E, Landeloos M, Jones D, Jenny NS, Van de Werf F, Tracy RP.

Clin Chem. 2006 Apr;52(4):760-4. Epub 2006 Feb 23. Erratum in: Clin Chem. 2006 Aug;52(8):1628. Nancy, Jenny S [corrected to Jenny, Nancy S]. PMID: 16497937 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor-alpha,gamma-agonist improves insulin sensitivity and prevents loss of left ventricular function in obese dyslipidemic mice.

Verreth W, Ganame J, Mertens A, Bernar H, Herregods MC, Holvoet P.

Arterioscler Thromb Vasc Biol. 2006 Apr;26(4):922-8. Epub 2006 Feb 2.PMID: 16456093 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipoprotein peroxidation and mobility limitation: results from the Health, Aging, and Body Composition Study.

Cesari M, Kritchevsky SB, Nicklas BJ, Penninx BW, Holvoet P, Koh-Banerjee P, Cummings SR, Harris TB, Newman AB, Pahor M.

Arch Intern Med. 2005 Oct 10;165(18):2148-54.PMID: 16217006 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of oxidatively modified low density lipoproteins and anti-oxidants in atherothrombosis.

Holvoet P.

Expert Opin Investig Drugs. 1999 May;8(5):527-44.PMID: 15992113 [PubMed]Related articles

Obesity, regional body fat distribution, and the metabolic syndrome in older men and women.

Goodpaster BH, Krishnaswami S, Harris TB, Katsiaras A, Kritchevsky SB, Simonsick EM, Nevitt M, Holvoet P, Newman AB.

Arch Intern Med. 2005 Apr 11;165(7):777-83.PMID: 15824297 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular and functional characterization of ovine cardiac valve-derived interstitial cells in primary isolates and cultures.

Yperman J, De Visscher G, Holvoet P, Flameng W.

Tissue Eng. 2004 Sep-Oct;10(9-10):1368-75.PMID: 15588397 [PubMed - indexed for MEDLINE]Related articles

Weight-loss-associated induction of peroxisome proliferator-activated receptor-alpha and peroxisome proliferator-activated receptor-gamma correlate with reduced atherosclerosis and improved cardiovascular function in obese insulin-resistant mice.

Verreth W, De Keyzer D, Pelat M, Verhamme P, Ganame J, Bielicki JK, Mertens A, Quarck R, Benhabilès N, Marguerie G, Mackness B, Mackness M, Ninio E, Herregods MC, Balligand JL, Holvoet P.

Circulation. 2004 Nov 16;110(20):3259-69. Epub 2004 Nov 8.PMID: 15533870 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidized LDL and coronary heart disease.

Holvoet P.

Acta Cardiol. 2004 Oct;59(5):479-84. Review.PMID: 15529550 [PubMed - indexed for MEDLINE]Related articles

Beta-actin cannot be used as a control for gene expression in ovine interstitial cells derived from heart valves.

Yperman J, De Visscher G, Holvoet P, Flameng W.

J Heart Valve Dis. 2004 Sep;13(5):848-53.PMID: 15473489 [PubMed - indexed for MEDLINE]Related articles

Gene therapy approaches for cardiovascular diseases.

Quarck R, Holvoet P.

Curr Gene Ther. 2004 Jun;4(2):207-23. Review.PMID: 15180587 [PubMed - indexed for MEDLINE]Related articles

The metabolic syndrome, circulating oxidized LDL, and risk of myocardial infarction in well-functioning elderly people in the health, aging, and body composition cohort.

Holvoet P, Kritchevsky SB, Tracy RP, Mertens A, Rubin SM, Butler J, Goodpaster B, Harris TB.

Diabetes. 2004 Apr;53(4):1068-73.PMID: 15047623 [PubMed - indexed for MEDLINE]Related articlesFree article

Alpha-helix formation is required for high affinity binding of human apolipoprotein A-I to lipids.

Saito H, Dhanasekaran P, Nguyen D, Deridder E, Holvoet P, Lund-Katz S, Phillips MC.

J Biol Chem. 2004 May 14;279(20):20974-81. Epub 2004 Mar 12.PMID: 15020600 [PubMed - indexed for MEDLINE]Related articlesFree article

Plaque-associated endothelial dysfunction in apolipoprotein E-deficient mice on a regular diet. Effect of human apolipoprotein AI.

Crauwels HM, Van Hove CE, Holvoet P, Herman AG, Bult H.

Cardiovasc Res. 2003 Jul 1;59(1):189-99.PMID: 12829190 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of high coronary heart disease risk status with circulating oxidized LDL in the well-functioning elderly: findings from the Health, Aging, and Body Composition study.

Holvoet P, Harris TB, Tracy RP, Verhamme P, Newman AB, Rubin SM, Simonsick EM, Colbert LH, Kritchevsky SB.

Arterioscler Thromb Vasc Biol. 2003 Aug 1;23(8):1444-8. Epub 2003 Jun 5.PMID: 12791672 [PubMed - indexed for MEDLINE]Related articlesFree article

Domain structure and lipid interaction in human apolipoproteins A-I and E, a general model.

Saito H, Dhanasekaran P, Nguyen D, Holvoet P, Lund-Katz S, Phillips MC.

J Biol Chem. 2003 Jun 27;278(26):23227-32. Epub 2003 Apr 22.PMID: 12709430 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased low-density lipoprotein oxidation and impaired high-density lipoprotein antioxidant defense are associated with increased macrophage homing and atherosclerosis in dyslipidemic obese mice: LCAT gene transfer decreases atherosclerosis.

Mertens A, Verhamme P, Bielicki JK, Phillips MC, Quarck R, Verreth W, Stengel D, Ninio E, Navab M, Mackness B, Mackness M, Holvoet P.

Circulation. 2003 Apr 1;107(12):1640-6. Epub 2003 Mar 24.PMID: 12668499 [PubMed - indexed for MEDLINE]Related articlesFree article

Chlamydia pneumoniae induces neointima formation in coronary arteries of normal pigs.

Pislaru SV, Van Ranst M, Pislaru C, Szelid Z, Theilmeier G, Ossewaarde JM, Holvoet P, Janssens S, Verbeken E, Van de Werf FJ.

Cardiovasc Res. 2003 Mar;57(3):834-42.PMID: 12618245 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased levels of low-density lipoprotein oxidation in patients with familial hypercholesterolemia and in end-stage renal disease patients on hemodialysis.

Van Tits L, De Graaf J, Hak-Lemmers H, Bredie S, Demacker P, Holvoet P, Stalenhoef A.

Lab Invest. 2003 Jan;83(1):13-21.PMID: 12533682 [PubMed - indexed for MEDLINE]Related articles

Effects of homocysteine on the cellular responses of murine endothelial cells cultured in vitro.

Tacheny A, dos Santos S, Huet AC, van Steenbrugge M, Michiels C, Holvoet P, Raes M.

Ann N Y Acad Sci. 2002 Nov;973:550-4.PMID: 12485927 [PubMed - indexed for MEDLINE]Related articles