PubMed

Reduced plasma levels of glucagon-like peptide-1 in elderly men are associated with impaired glucose tolerance but not with coronary heart disease.

Nathanson D, Zethelius B, Berne C, Holst JJ, Sjöholm A, Nyström T.

Diabetologia. 2009 Nov 21. [Epub ahead of print]PMID: 19936703 [PubMed - as supplied by publisher]

Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists.

Kielgast U, Holst JJ, Madsbad S.

Curr Diabetes Rev. 2009 Nov;5(4):266-75.PMID: 19925391 [PubMed - in process]Related articles

Postprandial diabetic glucose tolerance is normalized by gastric bypass feeding as opposed to gastric feeding and is associated with exaggerated GLP-1 secretion: a case report.

Dirksen C, Hansen DL, Madsbad S, Hvolris LE, Naver LS, Holst JJ, Worm D.

Diabetes Care. 2009 Nov 16. [Epub ahead of print]PMID: 19918005 [PubMed - as supplied by publisher]Related articles

The effect of glucagon-like peptide-2 on arterial blood flow and cardiac parameters.

Bremholm L, Hornum M, Andersen UB, Holst JJ.

Regul Pept. 2009 Nov 10. [Epub ahead of print]PMID: 19900491 [PubMed - as supplied by publisher]Related articles

Glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: new advances.

Asmar M, Holst JJ.

Curr Opin Endocrinol Diabetes Obes. 2009 Oct 29. [Epub ahead of print]PMID: 19881341 [PubMed - as supplied by publisher]Related articles

Effects of meal size and composition on incretin, alpha-cell, and beta-cell responses.

Rijkelijkhuizen JM, McQuarrie K, Girman CJ, Stein PP, Mari A, Holst JJ, Nijpels G, Dekker JM.

Metabolism. 2009 Oct 19. [Epub ahead of print]PMID: 19846181 [PubMed - as supplied by publisher]Related articles

Preserved Inhibitory Potency of GLP-1 on Glucagon Secretion in Type 2 Diabetes Mellitus.

Hare KJ, Knop FK, Asmar M, Madsbad S, Deacon CF, Holst JJ, Vilsbøll T.

J Clin Endocrinol Metab. 2009 Oct 16. [Epub ahead of print]PMID: 19837930 [PubMed - as supplied by publisher]Related articles

Whey protein potentiates the intestinotrophic action of glucagon-like peptide-2 in parenterally fed rats.

Liu X, Murali SG, Holst JJ, Ney DM.

Am J Physiol Regul Integr Comp Physiol. 2009 Nov;297(5):R1554-62. Epub 2009 Sep 23.PMID: 19776251 [PubMed - in process]Related articles

The spectrum of antidiabetic actions of GLP-1 in patients with diabetes.

Vilsbøll T, Holst JJ, Knop FK.

Best Pract Res Clin Endocrinol Metab. 2009 Aug;23(4):453-62.PMID: 19748063 [PubMed - in process]Related articles

Immunoassays for the incretin hormones GIP and GLP-1.

Deacon CF, Holst JJ.

Best Pract Res Clin Endocrinol Metab. 2009 Aug;23(4):425-32.PMID: 19748060 [PubMed - in process]Related articles

Cognitive performance, symptoms and counter-regulation during hypoglycaemia in patients with type 1 diabetes and high or low renin-angiotensin system activity.

Høi-Hansen T, Pedersen-Bjergaard U, Due-Andersen R, Kristensen PL, Thomsen CE, Kjær TW, Høgenhaven H, Smed A, Holst JJ, Dela F, Boomsma F, Thorsteinsson B.

J Renin Angiotensin Aldosterone Syst. 2009 Aug 28. [Epub ahead of print]PMID: 19717500 [PubMed - as supplied by publisher]Related articles

Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus.

Müssig K, Staiger H, Machicao F, Machann J, Schick F, Schäfer SA, Claussen CD, Holst JJ, Gallwitz B, Stefan N, Fritsche A, Häring HU.

Metabolism. 2009 Dec;58(12):1809-11. Epub 2009 Aug 28.PMID: 19716570 [PubMed - in process]Related articles

Mechanisms of Gastric Emptying Disturbances in Chronic and Acute Inflammation of the Distal Gastrointestinal Tract.

Keller J, Beglinger C, Holst JJ, Andresen V, Layer P.

Am J Physiol Gastrointest Liver Physiol. 2009 Aug 27. [Epub ahead of print]PMID: 19713472 [PubMed - as supplied by publisher]Related articles

Short bowel patients treated for two years with glucagon-like Peptide 2: effects on intestinal morphology and absorption, renal function, bone and body composition, and muscle function.

Jeppesen PB, Lund P, Gottschalck IB, Nielsen HB, Holst JJ, Mortensen J, Poulsen SS, Quistorff B, Mortensen PB.

Gastroenterol Res Pract. 2009;2009:616054. Epub 2009 Aug 20.PMID: 19707516 [PubMed - in process]Related articlesFree article

Differential effect of PYY1-36 and PYY3-36 on gastric emptying in man.

Witte AB, Grybäck P, Holst JJ, Hilsted L, Hellström PM, Jacobsson H, Schmidt PT.

Regul Pept. 2009 Nov 27;158(1-3):57-62. Epub 2009 Aug 3.PMID: 19651163 [PubMed - in process]Related articles

Colonic GLP-2 is not sufficient to promote jejunal adaptation in a PN-dependent rat model of human short bowel syndrome.

Koopmann MC, Liu X, Boehler CJ, Murali SG, Holst JJ, Ney DM.

JPEN J Parenter Enteral Nutr. 2009 Nov-Dec;33(6):629-38; discussion 638-9. Epub 2009 Jul 30.PMID: 19644131 [PubMed - in process]Related articles

Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD.

Henriksen DB, Alexandersen P, Hartmann B, Adrian CL, Byrjalsen I, Bone HG, Holst JJ, Christiansen C.

Bone. 2009 Nov;45(5):833-42. Epub 2009 Jul 22.PMID: 19631303 [PubMed - in process]Related articles

Lixisenatide, a novel GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus.

Christensen M, Knop FK, Holst JJ, Vilsboll T.

IDrugs. 2009 Aug;12(8):503-13. Review.PMID: 19629885 [PubMed - indexed for MEDLINE]Related articles

Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists.

Hansen KB, Knop FK, Holst JJ, Vilsbøll T.

Int J Clin Pract. 2009 Aug;63(8):1154-60.PMID: 19624785 [PubMed - in process]Related articles

Dissociated incretin response to oral glucose at 1 year after restrictive vs. malabsorptive bariatric surgery.

Guldstrand M, Ahrén B, Näslund E, Holst JJ, Adamson U.

Diabetes Obes Metab. 2009 Nov;11(11):1027-33. Epub 2009 Jul 13.PMID: 19614945 [PubMed - in process]Related articles

Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass.

Gelling RW, Vuguin PM, Du XQ, Cui L, Rømer J, Pederson RA, Leiser M, Sørensen H, Holst JJ, Fledelius C, Johansen PB, Fleischer N, McIntosh CH, Nishimura E, Charron MJ.

Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E695-707. Epub 2009 Jul 14.PMID: 19602585 [PubMed - indexed for MEDLINE]Related articles

Pathophysiology and aetiology of impaired fasting glycaemia and impaired glucose tolerance: does it matter for prevention and treatment of type 2 diabetes?

Faerch K, Borch-Johnsen K, Holst JJ, Vaag A.

Diabetologia. 2009 Sep;52(9):1714-23. Epub 2009 Jul 10.PMID: 19590846 [PubMed - in process]Related articles

Short Bowel Patients Treated for Two Years with Glucagon-Like Peptide 2 (GLP-2): Compliance, Safety, and Effects on Quality of Life.

Jeppesen PB, Lund P, Gottschalck IB, Nielsen HB, Holst JJ, Mortensen J, Poulsen SS, Quistorff B, Mortensen PB.

Gastroenterol Res Pract. 2009;2009:425759. Epub 2009 Jul 5.PMID: 19590736 [PubMed - in process]Related articlesFree article

Inhibition of neutral endopeptidase 24.11 does not potentiate the improvement in glycemic control obtained with dipeptidyl peptidase-4 inhibition in diabetic Goto-Kakizaki rats.

Simonsen L, Pilgaard S, Carr RD, Kanstrup AB, Holst JJ, Deacon CF.

Horm Metab Res. 2009 Nov;41(11):851-3. Epub 2009 Jul 3. No abstract available. PMID: 19579179 [PubMed - in process]Related articles

Improved tolerance to sequential glucose loading (Staub-Traugott effect): size and mechanisms.

Bonuccelli S, Muscelli E, Gastaldelli A, Barsotti E, Astiarraga BD, Holst JJ, Mari A, Ferrannini E.

Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E532-7. Epub 2009 Jun 16.PMID: 19531643 [PubMed - indexed for MEDLINE]Related articles

Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats.

Simonsen L, Pilgaard S, Orskov C, Hartmann B, Holst JJ, Deacon CF.

Diabetes Obes Metab. 2009 Sep;11(9):884-90. Epub 2009 Jun 5.PMID: 19508463 [PubMed - in process]Related articles

Impaired glucose-induced glucagon suppression after partial pancreatectomy.

Schrader H, Menge BA, Breuer TG, Ritter PR, Uhl W, Schmidt WE, Holst JJ, Meier JJ.

J Clin Endocrinol Metab. 2009 Aug;94(8):2857-63. Epub 2009 Jun 2.PMID: 19491219 [PubMed - indexed for MEDLINE]Related articles

Comparative effect of orally administered sodium butyrate before or after weaning on growth and several indices of gastrointestinal biology of piglets.

Le Gall M, Gallois M, Sève B, Louveau I, Holst JJ, Oswald IP, Lallès JP, Guilloteau P.

Br J Nutr. 2009 Nov;102(9):1285-96. Epub 2009 Jun 1.PMID: 19480733 [PubMed - in process]Related articles

Acute effects of casein on postprandial lipemia and incretin responses in type 2 diabetic subjects.

Brader L, Holm L, Mortensen L, Thomsen C, Astrup A, Holst JJ, de Vrese M, Schrezenmeir J, Hermansen K.

Nutr Metab Cardiovasc Dis. 2009 May 25. [Epub ahead of print]PMID: 19473824 [PubMed - as supplied by publisher]Related articles

Differential effects of protein quality on postprandial lipemia in response to a fat-rich meal in type 2 diabetes: comparison of whey, casein, gluten, and cod protein.

Mortensen LS, Hartvigsen ML, Brader LJ, Astrup A, Schrezenmeir J, Holst JJ, Thomsen C, Hermansen K.

Am J Clin Nutr. 2009 Jul;90(1):41-8. Epub 2009 May 20.PMID: 19458012 [PubMed - indexed for MEDLINE]Related articles

Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat.

Bucinskaite V, Tolessa T, Pedersen J, Rydqvist B, Zerihun L, Holst JJ, Hellström PM.

Neurogastroenterol Motil. 2009 Sep;21(9):978-e78. Epub 2009 May 13.PMID: 19453518 [PubMed - in process]Related articles

Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes.

Deacon CF, Holst JJ.

Adv Ther. 2009 May;26(5):488-99. Epub 2009 May 14.PMID: 19444391 [PubMed - in process]Related articles

Effect of viscosity on appetite and gastro-intestinal hormones.

Zijlstra N, Mars M, de Wijk RA, Westerterp-Plantenga MS, Holst JJ, de Graaf C.

Physiol Behav. 2009 Apr 20;97(1):68-75. Epub 2009 Feb 8.PMID: 19419670 [PubMed - indexed for MEDLINE]Related articles

Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity, and treatment with metformin.

Svendsen PF, Nilas L, Madsbad S, Holst JJ.

Metabolism. 2009 May;58(5):586-93.PMID: 19375579 [PubMed - indexed for MEDLINE]Related articles

Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion.

Müssig K, Staiger H, Machicao F, Kirchhoff K, Guthoff M, Schäfer SA, Kantartzis K, Silbernagel G, Stefan N, Holst JJ, Gallwitz B, Häring HU, Fritsche A.

Diabetes. 2009 Jul;58(7):1715-20. Epub 2009 Apr 14.PMID: 19366866 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism.

Patti ME, Houten SM, Bianco AC, Bernier R, Larsen PR, Holst JJ, Badman MK, Maratos-Flier E, Mun EC, Pihlajamaki J, Auwerx J, Goldfine AB.

Obesity (Silver Spring). 2009 Sep;17(9):1671-7. Epub 2009 Apr 9.PMID: 19360006 [PubMed - indexed for MEDLINE]Related articles

GLP-1 receptor agonists: targeting both hyperglycaemia and disease processes in diabetes.

Holst JJ, Seino Y.

Diabetes Res Clin Pract. 2009 Jul;85(1):1-3. Epub 2009 Mar 18. No abstract available. PMID: 19299027 [PubMed - indexed for MEDLINE]Related articles

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.

Pilgaard K, Jensen CB, Schou JH, Lyssenko V, Wegner L, Brøns C, Vilsbøll T, Hansen T, Madsbad S, Holst JJ, Vølund A, Poulsen P, Groop L, Pedersen O, Vaag AA.

Diabetologia. 2009 Jul;52(7):1298-307. Epub 2009 Mar 14.PMID: 19288077 [PubMed - indexed for MEDLINE]Related articles

[Surgical treatment of diabetes mellitus type 2]

Olesen SC, Hansen DL, Almdal T, Bendtsen F, Nordgaard I, Hvolris LE, Holst JJ, Naver L, Madsbad S.

Ugeskr Laeger. 2009 Feb 16;171(8):615-7. Danish. PMID: 19284908 [PubMed - indexed for MEDLINE]Related articles

Incretin-based therapy of type 2 diabetes mellitus.

Knop FK, Vilsbøll T, Holst JJ.

Curr Protein Pept Sci. 2009 Feb;10(1):46-55. Review.PMID: 19275672 [PubMed - indexed for MEDLINE]Related articles

Circadian rhythms of GIP and GLP1 in glucose-tolerant and in type 2 diabetic patients after biliopancreatic diversion.

Mingrone G, Nolfe G, Gissey GC, Iaconelli A, Leccesi L, Guidone C, Nanni G, Holst JJ.

Diabetologia. 2009 May;52(5):873-81. Epub 2009 Feb 20.PMID: 19229515 [PubMed - indexed for MEDLINE]Related articles

G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction.

Holst B, Egerod KL, Jin C, Petersen PS, Østergaard MV, Hald J, Sprinkel AM, Størling J, Mandrup-Poulsen T, Holst JJ, Thams P, Orskov C, Wierup N, Sundler F, Madsen OD, Schwartz TW.

Endocrinology. 2009 Jun;150(6):2577-85. Epub 2009 Feb 12.PMID: 19213833 [PubMed - indexed for MEDLINE]Related articles

Gut transit is associated with gastrointestinal symptoms and gut hormone profile in patients with cirrhosis.

Kalaitzakis E, Sadik R, Holst JJ, Ohman L, Björnsson E.

Clin Gastroenterol Hepatol. 2009 Mar;7(3):346-52. Epub 2008 Dec 3.PMID: 19200458 [PubMed - indexed for MEDLINE]Related articles

Hyperglycemia acutely lowers the postprandial excursions of glucagon-like Peptide-1 and gastric inhibitory polypeptide in humans.

Vollmer K, Gardiwal H, Menge BA, Goetze O, Deacon CF, Schmidt WE, Holst JJ, Meier JJ.

J Clin Endocrinol Metab. 2009 Apr;94(4):1379-85. Epub 2009 Jan 27.PMID: 19174495 [PubMed - indexed for MEDLINE]Related articles

Changes of cognition and regional cerebral activity during acute hypoglycemia in normal subjects: A H2 15O positron emission tomographic study.

Bie-Olsen LG, Kjaer TW, Pedersen-Bjergaard U, Lonsdale MN, Holst JJ, Law I, Thorsteinsson B.

J Neurosci Res. 2009 Jun;87(8):1922-8.PMID: 19170163 [PubMed - indexed for MEDLINE]Related articles

Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, insulin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and ghrelin concentrations in healthy subjects.

Hlebowicz J, Hlebowicz A, Lindstedt S, Björgell O, Höglund P, Holst JJ, Darwiche G, Almér LO.

Am J Clin Nutr. 2009 Mar;89(3):815-21. Epub 2009 Jan 21.PMID: 19158209 [PubMed - indexed for MEDLINE]Related articles

The effects of dietary fibre type on satiety-related hormones and voluntary food intake in dogs.

Bosch G, Verbrugghe A, Hesta M, Holst JJ, van der Poel AF, Janssens GP, Hendriks WH.

Br J Nutr. 2009 Jul;102(2):318-25. Epub 2009 Jan 15.PMID: 19144213 [PubMed - indexed for MEDLINE]Related articles

Orlistat accelerates gastric emptying and attenuates GIP release in healthy subjects.

Enç FY, Ones T, Akin HL, Dede F, Turoğlu HT, Ulfer G, Bekiroğlu N, Haklar G, Rehfeld JF, Holst JJ, Ulusoy NB, Imeryüz N.

Am J Physiol Gastrointest Liver Physiol. 2009 Mar;296(3):G482-9. Epub 2008 Dec 24.PMID: 19109408 [PubMed - indexed for MEDLINE]Related articles

No increased risk of hypoglycaemic episodes during 48 h of subcutaneous glucagon-like-peptide-1 administration in fasting healthy subjects.

Lerche S, Soendergaard L, Rungby J, Moeller N, Holst JJ, Schmitz OE, Brock B.

Clin Endocrinol (Oxf). 2009 Oct;71(4):500-6. Epub 2008 Dec 15.PMID: 19094067 [PubMed - in process]Related articles

Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract.

Gottschalck IB, Jeppesen PB, Holst JJ, Henriksen DB.

Scand J Gastroenterol. 2008 Aug;43(8):929-37.PMID: 19086164 [PubMed - indexed for MEDLINE]Related articles