PubMed

Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMPK activators in l6 myotubes.

Fazakerley DJ, Holman GD, Marley A, James DE, Stockli J, Coster AC.

J Biol Chem. 2009 Nov 13. [Epub ahead of print]PMID: 19915010 [PubMed - as supplied by publisher]Related articlesFree article

A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling.

Fazakerley DJ, Lawrence SP, Lizunov VA, Cushman SW, Holman GD.

J Cell Sci. 2009 Mar 1;122(Pt 5):727-34. Epub 2009 Feb 10. Erratum in: J Cell Sci. 2009 Apr 1;122(Pt 7):1054. PMID: 19208760 [PubMed - indexed for MEDLINE]Related articlesFree article

Kinetics of GLUT4 trafficking in rat and human skeletal muscle.

Karlsson HK, Chibalin AV, Koistinen HA, Yang J, Koumanov F, Wallberg-Henriksson H, Zierath JR, Holman GD.

Diabetes. 2009 Apr;58(4):847-54. Epub 2009 Feb 2.PMID: 19188436 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulating the motor for GLUT4 vesicle traffic.

Holman GD, Sakamoto K.

Cell Metab. 2008 Nov;8(5):344-6.PMID: 19046566 [PubMed - indexed for MEDLINE]Related articles

Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic.

Sakamoto K, Holman GD.

Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E29-37. Epub 2008 May 13. Review.PMID: 18477703 [PubMed - indexed for MEDLINE]Related articlesFree article

Thrifty Tbc1d1 and Tbc1d4 proteins link signalling and membrane trafficking pathways.

Koumanov F, Holman GD.

Biochem J. 2007 Apr 15;403(2):e9-11.PMID: 17376030 [PubMed - indexed for MEDLINE]Related articlesFree article

Infusion of a biotinylated bis-glucose photolabel: a new method to quantify cell surface GLUT4 in the intact mouse heart.

Miller EJ, Li J, Sinusas KM, Holman GD, Young LH.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1922-8. Epub 2007 Mar 6.PMID: 17341550 [PubMed - indexed for MEDLINE]Related articlesFree article

The mysterious origins of solar flares.

Holman GD.

Sci Am. 2006 Apr;294(4):38-45. No abstract available. PMID: 16596878 [PubMed]Related articles

Long-term metformin treatment stimulates cardiomyocyte glucose transport through an AMP-activated protein kinase-dependent reduction in GLUT4 endocytosis.

Yang J, Holman GD.

Endocrinology. 2006 Jun;147(6):2728-36. Epub 2006 Mar 2.PMID: 16513829 [PubMed - indexed for MEDLINE]Related articlesFree article

The human glomerular podocyte is a novel target for insulin action.

Coward RJ, Welsh GI, Yang J, Tasman C, Lennon R, Koziell A, Satchell S, Holman GD, Kerjaschki D, Tavaré JM, Mathieson PW, Saleem MA.

Diabetes. 2005 Nov;54(11):3095-102.PMID: 16249431 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin signaling meets vesicle traffic of GLUT4 at a plasma-membrane-activated fusion step.

Koumanov F, Jin B, Yang J, Holman GD.

Cell Metab. 2005 Sep;2(3):179-89.PMID: 16154100 [PubMed - indexed for MEDLINE]Related articles

Reduced insulin-stimulated GLUT4 bioavailability in stroke-prone spontaneously hypertensive rats.

Collison M, James DJ, Graham D, Holman GD, Connell JM, Dominiczak AF, Gould GW, Salt IP.

Diabetologia. 2005 Mar;48(3):539-46. Epub 2005 Feb 24.PMID: 15729573 [PubMed - indexed for MEDLINE]Related articles

Endofacial competitive inhibition of glucose transporter-4 intrinsic activity by the mitogen-activated protein kinase inhibitor SB203580.

Ribé D, Yang J, Patel S, Koumanov F, Cushman SW, Holman GD.

Endocrinology. 2005 Apr;146(4):1713-7. Epub 2005 Jan 20.PMID: 15661859 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin and contraction stimulate exocytosis, but increased AMP-activated protein kinase activity resulting from oxidative metabolism stress slows endocytosis of GLUT4 in cardiomyocytes.

Yang J, Holman GD.

J Biol Chem. 2005 Feb 11;280(6):4070-8. Epub 2004 Nov 22.PMID: 15557332 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle.

Li J, Hu X, Selvakumar P, Russell RR 3rd, Cushman SW, Holman GD, Young LH.

Am J Physiol Endocrinol Metab. 2004 Nov;287(5):E834-41. Epub 2004 Jul 20.PMID: 15265762 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalization.

Whitley P, Reaves BJ, Hashimoto M, Riley AM, Potter BV, Holman GD.

J Biol Chem. 2003 Oct 3;278(40):38786-95. Epub 2003 Jul 23.PMID: 12878588 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface.

Bentley J, Itchayanan D, Barnes K, McIntosh E, Tang X, Downes CP, Holman GD, Whetton AD, Owen-Lynch PJ, Baldwin SA.

J Biol Chem. 2003 Oct 10;278(41):39337-48. Epub 2003 Jul 16.PMID: 12869574 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin action in cultured human skeletal muscle cells during differentiation: assessment of cell surface GLUT4 and GLUT1 content.

Al-Khalili L, Chibalin AV, Kannisto K, Zhang BB, Permert J, Holman GD, Ehrenborg E, Ding VD, Zierath JR, Krook A.

Cell Mol Life Sci. 2003 May;60(5):991-8.PMID: 12827286 [PubMed - indexed for MEDLINE]Related articles

5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes.

Koistinen HA, Galuska D, Chibalin AV, Yang J, Zierath JR, Holman GD, Wallberg-Henriksson H.

Diabetes. 2003 May;52(5):1066-72.PMID: 12716734 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of the D-fructose transporter protein GLUT5 by fused-ring glyco-1,3-oxazolidin-2-thiones and -oxazolidin-2-ones.

Girniene J, Tatibouët A, Sackus A, Yang J, Holman GD, Rollin P.

Carbohydr Res. 2003 Apr 4;338(8):711-9.PMID: 12668090 [PubMed - indexed for MEDLINE]Related articles

Insulin-stimulated cytosol alkalinization facilitates optimal activation of glucose transport in cardiomyocytes.

Yang J, Gillingham AK, Hodel A, Koumanov F, Woodward B, Holman GD.

Am J Physiol Endocrinol Metab. 2002 Dec;283(6):E1299-307. Epub 2002 Aug 13.PMID: 12388133 [PubMed - indexed for MEDLINE]Related articlesFree article

Improvement in the properties of 3-phenyl-3-trifluoromethyldiazirine based photoreactive bis-glucose probes for GLUT4 following substitution on the phenyl ring.

Hashimoto M, Yang J, Hatanaka Y, Sadakane Y, Nakagomi K, Holman GD.

Chem Pharm Bull (Tokyo). 2002 Jul;50(7):1004-6.PMID: 12130867 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of high-affinity ligands and photoaffinity labels for the D-fructose transporter GLUT5.

Yang J, Dowden J, Tatibouët A, Hatanaka Y, Holman GD.

Biochem J. 2002 Oct 15;367(Pt 2):533-9.PMID: 12119043 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of centaurin-alpha2: a phosphatidylinositide-binding protein present in fat, heart and skeletal muscle.

Whitley P, Gibbard AM, Koumanov F, Oldfield S, Kilgour EE, Prestwich GD, Holman GD.

Eur J Cell Biol. 2002 Apr;81(4):222-30.PMID: 12018390 [PubMed - indexed for MEDLINE]Related articles

Cell-surface recognition of biotinylated membrane proteins requires very long spacer arms: an example from glucose-transporter probes.

Hashimoto M, Yang J, Holman GD.

Chembiochem. 2001 Jan 8;2(1):52-9.PMID: 11828427 [PubMed - indexed for MEDLINE]Related articles

Insulin and isoproterenol have opposing roles in the maintenance of cytosol pH and optimal fusion of GLUT4 vesicles with the plasma membrane.

Yang J, Hodel A, Holman GD.

J Biol Chem. 2002 Feb 22;277(8):6559-66. Epub 2002 Jan 7.PMID: 11751852 [PubMed - indexed for MEDLINE]Related articlesFree article

D-Fructose-L-sorbose interconversions. Access to 5-thio-D-fructose and interaction with the D-fructose transporter, GLUT5.

Tatibouët A, Lefoix M, Nadolny J, Martin OR, Rollin P, Yang J, Holman GD.

Carbohydr Res. 2001 Jul 19;333(4):327-34.PMID: 11454339 [PubMed - indexed for MEDLINE]Related articles

Synthesis of biotinylated bis(D-glucose) derivatives for glucose transporter photoaffinity labelling.

Hashimoto M, Hatanaka Y, Yang J, Dhesi J, Holman GD.

Carbohydr Res. 2001 Mar 22;331(2):119-27.PMID: 11322726 [PubMed - indexed for MEDLINE]Related articles

Moving the insulin-regulated glucose transporter GLUT4 into and out of storage.

Holman GD, Sandoval IV.

Trends Cell Biol. 2001 Apr;11(4):173-9. Review.PMID: 11306298 [PubMed - indexed for MEDLINE]Related articles

Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner.

Buhl ES, Jessen N, Schmitz O, Pedersen SB, Pedersen O, Holman GD, Lund S.

Diabetes. 2001 Jan;50(1):12-7.PMID: 11147776 [PubMed - indexed for MEDLINE]Related articlesFree article

Synthesis and evaluation of fructose analogues as inhibitors of the D-fructose transporter GLUT5.

Tatibouët A, Yang J, Morin C, Holman GD.

Bioorg Med Chem. 2000 Jul;8(7):1825-33.PMID: 10976531 [PubMed - indexed for MEDLINE]Related articles

Distinct reading of different structural determinants modulates the dileucine-mediated transport steps of the lysosomal membrane protein LIMPII and the insulin-sensitive glucose transporter GLUT4.

Sandoval IV, Martinez-Arca S, Valdueza J, Palacios S, Holman GD.

J Biol Chem. 2000 Dec 22;275(51):39874-85.PMID: 10973972 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of a novel impermeable biotinylated photolabeling reagent to assess insulin- and hypoxia-stimulated cell surface GLUT4 content in skeletal muscle from type 2 diabetic patients.

Ryder JW, Yang J, Galuska D, Rincón J, Björnholm M, Krook A, Lund S, Pedersen O, Wallberg-Henriksson H, Zierath JR, Holman GD.

Diabetes. 2000 Apr;49(4):647-54.PMID: 10871204 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic insulin effects on insulin signalling and GLUT4 endocytosis are reversed by metformin.

Pryor PR, Liu SC, Clark AE, Yang J, Holman GD, Tosh D.

Biochem J. 2000 May 15;348 Pt 1:83-91.PMID: 10794717 [PubMed - indexed for MEDLINE]Related articlesFree article

Contraction-stimulated muscle glucose transport and GLUT-4 surface content are dependent on glycogen content.

Derave W, Lund S, Holman GD, Wojtaszewski J, Pedersen O, Richter EA.

Am J Physiol. 1999 Dec;277(6 Pt 1):E1103-10.PMID: 10600801 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of AP1 adaptor complexes with GLUT4 vesicles.

Gillingham AK, Koumanov F, Pryor PR, Reaves BJ, Holman GD.

J Cell Sci. 1999 Dec;112 ( Pt 24):4793-800.PMID: 10574726 [PubMed - indexed for MEDLINE]Related articlesFree article

A new deadly Syn?

Holman GD.

Curr Biol. 1999 Oct 7;9(19):R735-7. Review.PMID: 10530997 [PubMed - indexed for MEDLINE]Related articles

In vitro analysis of the glucose-transport system in GLUT4-null skeletal muscle.

Ryder JW, Kawano Y, Chibalin AV, Rincón J, Tsao TS, Stenbit AE, Combatsiaris T, Yang J, Holman GD, Charron MJ, Zierath JR.

Biochem J. 1999 Sep 1;342 ( Pt 2):321-8.PMID: 10455018 [PubMed - indexed for MEDLINE]Related articlesFree article

Blood-brain barrier glucose transporter: effects of hypo- and hyperglycemia revisited.

Simpson IA, Appel NM, Hokari M, Oki J, Holman GD, Maher F, Koehler-Stec EM, Vannucci SJ, Smith QR.

J Neurochem. 1999 Jan;72(1):238-47.PMID: 9886075 [PubMed - indexed for MEDLINE]Related articles

Insulin-sensitive regulation of glucose transport and GLUT4 translocation in skeletal muscle of GLUT1 transgenic mice.

Etgen GJ Jr, Zavadoski WJ, Holman GD, Gibbs EM.

Biochem J. 1999 Jan 1;337 ( Pt 1):51-7.PMID: 9854024 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell-surface biotinylation of GLUT4 using bis-mannose photolabels.

Koumanov F, Yang J, Jones AE, Hatanaka Y, Holman GD.

Biochem J. 1998 Mar 15;330 ( Pt 3):1209-15.PMID: 9494087 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence against protein kinase B as a mediator of contraction-induced glucose transport and GLUT4 translocation in rat skeletal muscle.

Lund S, Pryor PR, Ostergaard S, Schmitz O, Pedersen O, Holman GD.

FEBS Lett. 1998 Apr 3;425(3):472-4.PMID: 9563515 [PubMed - indexed for MEDLINE]Related articles

Serine-294 and threonine-295 in the exofacial loop domain between helices 7 and 8 of glucose transporters (GLUT) are involved in the conformational alterations during the transport process.

Doege H, Schürmann A, Ohnimus H, Monser V, Holman GD, Joost HG.

Biochem J. 1998 Jan 15;329 ( Pt 2):289-93.PMID: 9425111 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of insulin on GLUT4 cell surface content and turnover rate in human skeletal muscle as measured by the exofacial bis-mannose photolabeling technique.

Lund S, Holman GD, Zierath JR, Rincon J, Nolte LA, Clark AE, Schmitz O, Pedersen O, Wallberg-Henriksson H.

Diabetes. 1997 Dec;46(12):1965-9.PMID: 9392481 [PubMed - indexed for MEDLINE]Related articles

From receptor to transporter: insulin signalling to glucose transport.

Holman GD, Kasuga M.

Diabetologia. 1997 Sep;40(9):991-1003. Review. No abstract available. PMID: 9300235 [PubMed - indexed for MEDLINE]Related articles

In situ labelling of insulin stimulated GTP-binding proteins in adipocytes.

Pryor PR, Young PW, Holman GD.

Biochem Soc Trans. 1997 Aug;25(3):475S. No abstract available. PMID: 9388696 [PubMed - indexed for MEDLINE]Related articles

Cell surface biotinylation of GLUT4.

Koumanov F, Yang J, Jones A, Hatanaka Y, Holman GD.

Biochem Soc Trans. 1997 Aug;25(3):470S. No abstract available. PMID: 9388691 [PubMed - indexed for MEDLINE]Related articles

Alterted GLUT4 subcellular trafficking in primary cultures of rat adipocytes.

Tosh D, Clark AE, Pryor PR, Yang J, Holman GD.

Biochem Soc Trans. 1997 Aug;25(3):469S. No abstract available. PMID: 9388690 [PubMed - indexed for MEDLINE]Related articles

GLUT4 translocation in human muscle strips.

Lund S, Pedersen O, Holman GD, Clark AE, Zierath JR, Wallberg-Henriksson H.

Biochem Soc Trans. 1997 Aug;25(3):466S. No abstract available. PMID: 9388687 [PubMed - indexed for MEDLINE]Related articles

Cell biology of insulin action on glucose transport.

Cushman W, Satoh S, Timmers KI, Malide D, Holman GD.

Jpn J Physiol. 1997;47 Suppl 1:S39. No abstract available. PMID: 9266324 [PubMed - indexed for MEDLINE]Related articles