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Effects of long-term calorie restriction and endurance exercise on glucose tolerance, insulin action, and adipokine production.

Fontana L, Klein S, Holloszy JO.

Age (Dordr). 2009 Nov 11. [Epub ahead of print]PMID: 19904628 [PubMed - as supplied by publisher]Related articles

Is "fat-induced" muscle insulin resistance rapidly reversible?

Han DH, Hancock C, Jung SR, Holloszy JO.

Am J Physiol Endocrinol Metab. 2009 Jul;297(1):E236-41. Epub 2009 May 12.PMID: 19435855 [PubMed - indexed for MEDLINE]Related articles

Effects of 7 days of exercise training on insulin sensitivity and responsiveness in type 2 diabetes mellitus.

Kirwan JP, Solomon TP, Wojta DM, Staten MA, Holloszy JO.

Am J Physiol Endocrinol Metab. 2009 Jul;297(1):E151-6. Epub 2009 Apr 21.PMID: 19383872 [PubMed - indexed for MEDLINE]Related articles

Dehydroepiandrosterone replacement therapy in older adults: 1- and 2-y effects on bone.

Weiss EP, Shah K, Fontana L, Lambert CP, Holloszy JO, Villareal DT.

Am J Clin Nutr. 2009 May;89(5):1459-67. Epub 2009 Mar 25.PMID: 19321570 [PubMed - indexed for MEDLINE]Related articles

IGF-1, nutrition and aging: the big picture.

Fontana L, Weiss EP, Villareal DT, Klein S, Holloszy JO.

Aging Cell. 2009 Mar 5. [Epub ahead of print] No abstract available. PMID: 19281497 [PubMed - as supplied by publisher]Related articles

Regulation by exercise of skeletal muscle content of mitochondria and GLUT4.

Holloszy JO.

J Physiol Pharmacol. 2008 Dec;59 Suppl 7:5-18. Review.PMID: 19258654 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise: it's the real thing!

Hawley JA, Holloszy JO.

Nutr Rev. 2009 Mar;67(3):172-8. Review.PMID: 19239632 [PubMed - indexed for MEDLINE]Related articles

Skeletal muscle "mitochondrial deficiency" does not mediate insulin resistance.

Holloszy JO.

Am J Clin Nutr. 2009 Jan;89(1):463S-6S. Epub 2008 Dec 3. Review.PMID: 19056574 [PubMed - indexed for MEDLINE]Related articles

Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans.

Fontana L, Weiss EP, Villareal DT, Klein S, Holloszy JO.

Aging Cell. 2008 Oct;7(5):681-7.PMID: 18843793 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial function after high-sugar-food ingestion improves with endurance exercise performed on the previous day.

Weiss EP, Arif H, Villareal DT, Marzetti E, Holloszy JO.

Am J Clin Nutr. 2008 Jul;88(1):51-7.PMID: 18614723 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of weekend lifestyle patterns on body weight.

Racette SB, Weiss EP, Schechtman KB, Steger-May K, Villareal DT, Obert KA, Holloszy JO.

Obesity (Silver Spring). 2008 Aug;16(8):1826-30. Epub 2008 Jun 12.PMID: 18551108 [PubMed - indexed for MEDLINE]Related articles

High-fat diets cause insulin resistance despite an increase in muscle mitochondria.

Hancock CR, Han DH, Chen M, Terada S, Yasuda T, Wright DC, Holloszy JO.

Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7815-20. Epub 2008 May 28.PMID: 18509063 [PubMed - indexed for MEDLINE]Related articlesFree article

The effects of caloric restriction- and exercise-induced weight loss on left ventricular diastolic function.

Riordan MM, Weiss EP, Meyer TE, Ehsani AA, Racette SB, Villareal DT, Fontana L, Holloszy JO, Kovács SJ.

Am J Physiol Heart Circ Physiol. 2008 Mar;294(3):H1174-82. Epub 2007 Dec 27.PMID: 18162561 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for the transcriptional coactivator PGC-1alpha in muscle refueling.

Wende AR, Schaeffer PJ, Parker GJ, Zechner C, Han DH, Chen MM, Hancock CR, Lehman JJ, Huss JM, McClain DA, Holloszy JO, Kelly DP.

J Biol Chem. 2007 Dec 14;282(50):36642-51. Epub 2007 Oct 11.PMID: 17932032 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of methods for assessing abdominal adipose tissue from magnetic resonance images.

Arif H, Racette SB, Villareal DT, Holloszy JO, Weiss EP.

Obesity (Silver Spring). 2007 Sep;15(9):2240-4.PMID: 17890492 [PubMed - indexed for MEDLINE]Related articles

Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle.

Garcia-Roves P, Huss JM, Han DH, Hancock CR, Iglesias-Gutierrez E, Chen M, Holloszy JO.

Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10709-13. Epub 2007 Jun 4.PMID: 17548828 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term low-calorie low-protein vegan diet and endurance exercise are associated with low cardiometabolic risk.

Fontana L, Meyer TE, Klein S, Holloszy JO.

Rejuvenation Res. 2007 Jun;10(2):225-34.PMID: 17518696 [PubMed - indexed for MEDLINE]Related articles

Calcium induces increases in peroxisome proliferator-activated receptor gamma coactivator-1alpha and mitochondrial biogenesis by a pathway leading to p38 mitogen-activated protein kinase activation.

Wright DC, Geiger PC, Han DH, Jones TE, Holloszy JO.

J Biol Chem. 2007 Jun 29;282(26):18793-9. Epub 2007 May 7.PMID: 17488713 [PubMed - indexed for MEDLINE]Related articlesFree article

Caloric restriction in humans.

Holloszy JO, Fontana L.

Exp Gerontol. 2007 Aug;42(8):709-12. Epub 2007 Mar 31. Review.PMID: 17482403 [PubMed - indexed for MEDLINE]Related articlesFree article

Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial.

Fontana L, Villareal DT, Weiss EP, Racette SB, Steger-May K, Klein S, Holloszy JO; and the Washington University School of Medicine CALERIE Group.

Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E197-202. Epub 2007 Mar 27.PMID: 17389710 [PubMed - indexed for MEDLINE]Related articlesFree article

Improvements in body composition, glucose tolerance, and insulin action induced by increasing energy expenditure or decreasing energy intake.

Weiss EP, Holloszy JO.

J Nutr. 2007 Apr;137(4):1087-90.PMID: 17374683 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-6 increases muscle insulin sensitivity only at superphysiological levels.

Geiger PC, Hancock C, Wright DC, Han DH, Holloszy JO.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1842-6. Epub 2007 Feb 27.PMID: 17327367 [PubMed - indexed for MEDLINE]Related articlesFree article

Bone mineral density response to caloric restriction-induced weight loss or exercise-induced weight loss: a randomized controlled trial.

Villareal DT, Fontana L, Weiss EP, Racette SB, Steger-May K, Schechtman KB, Klein S, Holloszy JO.

Arch Intern Med. 2006 Dec 11-25;166(22):2502-10. Erratum in: Arch Intern Med. 2007 Mar 12;167(5):452. PMID: 17159017 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term low-protein, low-calorie diet and endurance exercise modulate metabolic factors associated with cancer risk.

Fontana L, Klein S, Holloszy JO.

Am J Clin Nutr. 2006 Dec;84(6):1456-62.PMID: 17158430 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise-induced mitochondrial biogenesis begins before the increase in muscle PGC-1alpha expression.

Wright DC, Han DH, Garcia-Roves PM, Geiger PC, Jones TE, Holloszy JO.

J Biol Chem. 2007 Jan 5;282(1):194-9. Epub 2006 Nov 12.PMID: 17099248 [PubMed - indexed for MEDLINE]Related articlesFree article

Lower extremity muscle size and strength and aerobic capacity decrease with caloric restriction but not with exercise-induced weight loss.

Weiss EP, Racette SB, Villareal DT, Fontana L, Steger-May K, Schechtman KB, Klein S, Ehsani AA, Holloszy JO; Washington University School of Medicine CALERIE Group.

J Appl Physiol. 2007 Feb;102(2):634-40. Epub 2006 Nov 9.PMID: 17095635 [PubMed - indexed for MEDLINE]Related articlesFree article

Improvements in glucose tolerance and insulin action induced by increasing energy expenditure or decreasing energy intake: a randomized controlled trial.

Weiss EP, Racette SB, Villareal DT, Fontana L, Steger-May K, Schechtman KB, Klein S, Holloszy JO; Washington University School of Medicine CALERIE Group.

Am J Clin Nutr. 2006 Nov;84(5):1033-42.PMID: 17093155 [PubMed - indexed for MEDLINE]Related articlesFree article

One year of caloric restriction in humans: feasibility and effects on body composition and abdominal adipose tissue.

Racette SB, Weiss EP, Villareal DT, Arif H, Steger-May K, Schechtman KB, Fontana L, Klein S, Holloszy JO; Washington University School of Medicine CALERIE Group.

J Gerontol A Biol Sci Med Sci. 2006 Sep;61(9):943-50.PMID: 16960025 [PubMed - indexed for MEDLINE]Related articles

How muscle insulin sensitivity is regulated: testing of a hypothesis.

Geiger PC, Han DH, Wright DC, Holloszy JO.

Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1258-63. Epub 2006 Jul 11.PMID: 16835397 [PubMed - indexed for MEDLINE]Related articlesFree article

DHEA enhances effects of weight training on muscle mass and strength in elderly women and men.

Villareal DT, Holloszy JO.

Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E1003-8. Epub 2006 Jun 20.PMID: 16787962 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of long-term calorie restriction with adequate protein and micronutrients on thyroid hormones.

Fontana L, Klein S, Holloszy JO, Premachandra BN.

J Clin Endocrinol Metab. 2006 Aug;91(8):3232-5. Epub 2006 May 23.PMID: 16720655 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of calpain results in impaired contraction-stimulated GLUT4 translocation in skeletal muscle.

Otani K, Polonsky KS, Holloszy JO, Han DH.

Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E544-8. Epub 2006 May 16.PMID: 16705056 [PubMed - indexed for MEDLINE]Related articlesFree article

Abdominal adiposity is a stronger predictor of insulin resistance than fitness among 50-95 year olds.

Racette SB, Evans EM, Weiss EP, Hagberg JM, Holloszy JO.

Diabetes Care. 2006 Mar;29(3):673-8.PMID: 16505525 [PubMed - indexed for MEDLINE]Related articlesFree article

Gender differences in the decline in aerobic capacity and its physiological determinants during the later decades of life.

Weiss EP, Spina RJ, Holloszy JO, Ehsani AA.

J Appl Physiol. 2006 Sep;101(3):938-44. Epub 2006 Feb 23.PMID: 16497840 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term caloric restriction ameliorates the decline in diastolic function in humans.

Meyer TE, Kovács SJ, Ehsani AA, Klein S, Holloszy JO, Fontana L.

J Am Coll Cardiol. 2006 Jan 17;47(2):398-402.PMID: 16412867 [PubMed - indexed for MEDLINE]Related articles

Role of calcineurin in exercise-induced mitochondrial biogenesis.

Garcia-Roves PM, Huss J, Holloszy JO.

Am J Physiol Endocrinol Metab. 2006 Jun;290(6):E1172-9. Epub 2006 Jan 10.PMID: 16403773 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of progressive resistance training on body composition in frail older adults: results of a randomized, controlled trial.

Binder EF, Yarasheski KE, Steger-May K, Sinacore DR, Brown M, Schechtman KB, Holloszy JO.

J Gerontol A Biol Sci Med Sci. 2005 Nov;60(11):1425-31.PMID: 16339329 [PubMed - indexed for MEDLINE]Related articles

PPARdelta activator GW-501516 has no acute effect on glucose transport in skeletal muscle.

Terada S, Wicke S, Holloszy JO, Han DH.

Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E607-11. Epub 2005 Nov 8.PMID: 16278250 [PubMed - indexed for MEDLINE]Related articlesFree article

Are tyrosine kinases involved in mediating contraction-stimulated muscle glucose transport?

Wright DC, Geiger PC, Han DH, Holloszy JO.

Am J Physiol Endocrinol Metab. 2006 Jan;290(1):E123-E128. Epub 2005 Sep 13.PMID: 16159907 [PubMed - indexed for MEDLINE]Related articlesFree article

A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes.

Finck BN, Bernal-Mizrachi C, Han DH, Coleman T, Sambandam N, LaRiviere LL, Holloszy JO, Semenkovich CF, Kelly DP.

Cell Metab. 2005 Feb;1(2):133-44.PMID: 16054054 [PubMed - indexed for MEDLINE]Related articles

Exercise-induced increase in muscle insulin sensitivity.

Holloszy JO.

J Appl Physiol. 2005 Jul;99(1):338-43. Review.PMID: 16036907 [PubMed - indexed for MEDLINE]Related articlesFree article

Modest weight loss improves insulin action in obese African Americans.

Racette SB, Weiss EP, Hickner RC, Holloszy JO.

Metabolism. 2005 Jul;54(7):960-5.PMID: 15988708 [PubMed - indexed for MEDLINE]Related articlesFree article

Low bone mass in subjects on a long-term raw vegetarian diet.

Fontana L, Shew JL, Holloszy JO, Villareal DT.

Arch Intern Med. 2005 Mar 28;165(6):684-9.PMID: 15795346 [PubMed - indexed for MEDLINE]Related articlesFree article

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.

Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, Abel ED, Semenkovich CF, Kelly DP.

PLoS Biol. 2005 Apr;3(4):e101. Epub 2005 Mar 15.PMID: 15760270 [PubMed - indexed for MEDLINE]Related articlesFree article

Calcineurin does not mediate exercise-induced increase in muscle GLUT4.

Garcia-Roves PM, Jones TE, Otani K, Han DH, Holloszy JO.

Diabetes. 2005 Mar;54(3):624-8.PMID: 15734836 [PubMed - indexed for MEDLINE]Related articlesFree article

Contraction- and hypoxia-stimulated glucose transport is mediated by a Ca2+-dependent mechanism in slow-twitch rat soleus muscle.

Wright DC, Geiger PC, Holloszy JO, Han DH.

Am J Physiol Endocrinol Metab. 2005 Jun;288(6):E1062-6. Epub 2005 Jan 18.PMID: 15657088 [PubMed - indexed for MEDLINE]Related articlesFree article

Aerobic power and insulin action improve in response to endurance exercise training in healthy 77-87 yr olds.

Evans EM, Racette SB, Peterson LR, Villareal DT, Greiwe JS, Holloszy JO.

J Appl Physiol. 2005 Jan;98(1):40-5.PMID: 15591302 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of p38 MAP kinase enhances sensitivity of muscle glucose transport to insulin.

Geiger PC, Wright DC, Han DH, Holloszy JO.

Am J Physiol Endocrinol Metab. 2005 Apr;288(4):E782-8. Epub 2004 Dec 7.PMID: 15585585 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial.

Villareal DT, Holloszy JO.

JAMA. 2004 Nov 10;292(18):2243-8.PMID: 15536111 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans.

Fontana L, Meyer TE, Klein S, Holloszy JO.

Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6659-63. Epub 2004 Apr 19.PMID: 15096581 [PubMed - indexed for MEDLINE]Related articlesFree article