PubMed

Stop and go: yes or no?

Hochster HS.

J Clin Oncol. 2009 Dec 1;27(34):5677-9. Epub 2009 Sep 28. No abstract available. PMID: 19786651 [PubMed - in process]Related articles

Phase II Study of Paclitaxel Plus the Protein Kinase C Inhibitor Bryostatin-1 in Advanced Pancreatic Carcinoma.

Lam AP, Sparano JA, Vinciguerra V, Ocean AJ, Christos P, Hochster H, Camacho F, Goel S, Mani S, Kaubisch A.

Am J Clin Oncol. 2009 Sep 4. [Epub ahead of print]PMID: 19738452 [PubMed - as supplied by publisher]Related articles

Phase III, randomized study of gemcitabine and oxaliplatin versus gemcitabine (fixed-dose rate infusion) compared with gemcitabine (30-minute infusion) in patients with pancreatic carcinoma E6201: a trial of the Eastern Cooperative Oncology Group.

Poplin E, Feng Y, Berlin J, Rothenberg ML, Hochster H, Mitchell E, Alberts S, O'Dwyer P, Haller D, Catalano P, Cella D, Benson AB 3rd.

J Clin Oncol. 2009 Aug 10;27(23):3778-85. Epub 2009 Jul 6.PMID: 19581537 [PubMed - indexed for MEDLINE]Related articles

Phase II study of darinaparsin in patients with advanced hepatocellular carcinoma.

Wu J, Henderson C, Feun L, Van Veldhuizen P, Gold P, Zheng H, Ryan T, Blaszkowsky LS, Chen H, Costa M, Rosenzweig B, Nierodzik M, Hochster H, Muggia F, Abbadessa G, Lewis J, Zhu AX.

Invest New Drugs. 2009 Jun 30. [Epub ahead of print]PMID: 19565187 [PubMed - as supplied by publisher]Related articles

The power of "p": on overpowered clinical trials and "positive" results.

Hochster HS.

Gastrointest Cancer Res. 2008 Mar;2(2):108-9. No abstract available. PMID: 19259305 [PubMed - in process]Related articlesFree article

Rationale for combining biotherapy in the treatment of advanced colon cancer.

Cohen DJ, Hochster HS.

Gastrointest Cancer Res. 2008 May;2(3):145-51.PMID: 19259292 [PubMed - in process]Related articlesFree article

Maintenance rituximab after cyclophosphamide, vincristine, and prednisone prolongs progression-free survival in advanced indolent lymphoma: results of the randomized phase III ECOG1496 Study.

Hochster H, Weller E, Gascoyne RD, Habermann TM, Gordon LI, Ryan T, Zhang L, Colocci N, Frankel S, Horning SJ.

J Clin Oncol. 2009 Apr 1;27(10):1607-14. Epub 2009 Mar 2.PMID: 19255334 [PubMed - indexed for MEDLINE]Related articles

Phase I study of bryostatin 1, a protein kinase C modulator, preceding cisplatin in patients with refractory non-hematologic tumors.

Pavlick AC, Wu J, Roberts J, Rosenthal MA, Hamilton A, Wadler S, Farrell K, Carr M, Fry D, Murgo AJ, Oratz R, Hochster H, Liebes L, Muggia F.

Cancer Chemother Pharmacol. 2009 Sep;64(4):803-10. Epub 2009 Feb 17.PMID: 19221754 [PubMed - indexed for MEDLINE]Related articles

Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: a pooled analysis of randomized trials.

Arkenau HT, Arnold D, Cassidy J, Diaz-Rubio E, Douillard JY, Hochster H, Martoni A, Grothey A, Hinke A, Schmiegel W, Schmoll HJ, Porschen R.

J Clin Oncol. 2008 Dec 20;26(36):5910-7. Epub 2008 Nov 17.PMID: 19018087 [PubMed - indexed for MEDLINE]Related articles

Phase I/II trial of induction chemotherapy followed by concurrent chemoradiotherapy and surgery for locoregionally advanced pancreatic cancer.

Marti JL, Hochster HS, Hiotis SP, Donahue B, Ryan T, Newman E.

Ann Surg Oncol. 2008 Dec;15(12):3521-31. Epub 2008 Oct 2.PMID: 18830756 [PubMed - indexed for MEDLINE]Related articles

Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer: results of the TREE Study.

Hochster HS, Hart LL, Ramanathan RK, Childs BH, Hainsworth JD, Cohn AL, Wong L, Fehrenbacher L, Abubakr Y, Saif MW, Schwartzberg L, Hedrick E.

J Clin Oncol. 2008 Jul 20;26(21):3523-9. Erratum in: J Clin Oncol. 2008 Oct 1;26(28): 4697. PMID: 18640933 [PubMed - indexed for MEDLINE]Related articles

Bortezomib with or without irinotecan in relapsed or refractory colorectal cancer: results from a randomized phase II study.

Kozuch PS, Rocha-Lima CM, Dragovich T, Hochster H, O'Neil BH, Atiq OT, Pipas JM, Ryan DP, Lenz HJ.

J Clin Oncol. 2008 May 10;26(14):2320-6.PMID: 18467723 [PubMed - indexed for MEDLINE]Related articles

Update on clinical data with regimens inhibiting angiogenesis and epidermal growth factor receptor for patients with newly diagnosed metastatic colorectal cancer.

Cohen DJ, Hochster HS.

Clin Colorectal Cancer. 2007 Dec;7 Suppl 1:S21-7. Review.PMID: 18361803 [PubMed - indexed for MEDLINE]Related articles

VEGF inhibition and renal thrombotic microangiopathy.

Eremina V, Jefferson JA, Kowalewska J, Hochster H, Haas M, Weisstuch J, Richardson C, Kopp JB, Kabir MG, Backx PH, Gerber HP, Ferrara N, Barisoni L, Alpers CE, Quaggin SE.

N Engl J Med. 2008 Mar 13;358(11):1129-36.PMID: 18337603 [PubMed - indexed for MEDLINE]Related articles

Tolerance and activity of oxaliplatin with protracted topotecan infusion in patients with previously treated ovarian cancer. A phase I study.

Hochster H, Chen TT, Lu JM, Hills D, Sorich J, Escalon J, Ivy P, Liebes L, Muggia F.

Gynecol Oncol. 2008 Mar;108(3):500-4. Epub 2008 Jan 11.PMID: 18191187 [PubMed - indexed for MEDLINE]Related articles

Phase II study of uracil-tegafur with leucovorin in elderly (> or = 75 years old) patients with colorectal cancer: ECOG 1299.

Hochster HS, Luo W, Popa EC, Lyman BT, Mulcahy M, Beatty PA, Benson AB.

J Clin Oncol. 2007 Dec 1;25(34):5397-402.PMID: 18048821 [PubMed - indexed for MEDLINE]Related articles

Section III: Treatment of Advanced Gastrointestinal Cancers.

Hochster HS, O'Reilly EM, Ajani JA, Venook AP.

Gastrointest Cancer Res. 2007 Nov;1(6 Suppl):S8-S12. No abstract available. PMID: 19330060 [PubMed - in process]Related articlesFree article

Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in irinotecan-refractory colorectal cancer: the BOND-2 study.

Saltz LB, Lenz HJ, Kindler HL, Hochster HS, Wadler S, Hoff PM, Kemeny NE, Hollywood EM, Gonen M, Quinones M, Morse M, Chen HX.

J Clin Oncol. 2007 Oct 10;25(29):4557-61. Epub 2007 Sep 17.PMID: 17876013 [PubMed - indexed for MEDLINE]Related articles

Use of calcium and magnesium salts to reduce oxaliplatin-related neurotoxicity.

Hochster HS, Grothey A, Childs BH.

J Clin Oncol. 2007 Sep 1;25(25):4028-9. Epub 2007 Jul 30. No abstract available. PMID: 17664456 [PubMed - indexed for MEDLINE]Related articles

Adjuvant Therapy for Stage II and III Colon Cancer: Consensus Report of the International Society of Gastrointestinal Oncology.

Marshall JL, Haller DG, de Gramont A, Hochster HS, Lenz HJ, Ajani JA, Goldberg RM.

Gastrointest Cancer Res. 2007 Jul;1(4):146-54.PMID: 19262703 [PubMed - in process]Related articlesFree article

A phase II study of milataxel: a novel taxane analogue in previously treated patients with advanced colorectal cancer.

Ramanathan RK, Picus J, Raftopoulos H, Bernard S, Lockhart AC, Frenette G, Macdonald J, Melin S, Berg D, Brescia F, Hochster H, Cohn A.

Cancer Chemother Pharmacol. 2008 Mar;61(3):453-8. Epub 2007 May 22.PMID: 17516069 [PubMed - indexed for MEDLINE]Related articles

When is a line not a line?

Hochster HS.

Gastrointest Cancer Res. 2007 Mar;1(2):68-9. No abstract available. PMID: 19262723 [PubMed - in process]Related articlesFree article

Bevacizumab in combination with chemotherapy: first-line treatment of patients with metastatic colorectal cancer.

Hochster HS.

Semin Oncol. 2006 Oct;33(5 Suppl 10):S8-14. Review.PMID: 17145525 [PubMed - indexed for MEDLINE]Related articles

Phase II trial of nolatrexed dihydrochloride [Thymitaq, AG 337] in patients with advanced hepatocellular carcinoma.

Jhawer M, Rosen L, Dancey J, Hochster H, Hamburg S, Tempero M, Clendeninn N, Mani S.

Invest New Drugs. 2007 Feb;25(1):85-94. Epub 2006 Sep 7.PMID: 16957834 [PubMed - indexed for MEDLINE]Related articles

Consensus report of the international society of gastrointestinal oncology on therapeutic progress in advanced pancreatic cancer.

Hochster HS, Haller DG, de Gramont A, Berlin JD, Philip PA, Moore MJ, Ajani JA.

Cancer. 2006 Aug 15;107(4):676-85.PMID: 16847885 [PubMed - indexed for MEDLINE]Related articlesFree article

Topotecan continuous infusion: CA-125 responses including patients pretreated with other schedules of topotecan.

Muggia F, Kosloff R, Liebes L, Hochster H.

Oncologist. 2006 May;11(5):529-31; author reply 531-2. No abstract available. PMID: 16720854 [PubMed - indexed for MEDLINE]Related articlesFree article

Neoadjuvant chemotherapy, surgery, and adjuvant intraperitoneal chemotherapy in patients with locally advanced gastric or gastroesophageal junction carcinoma: a phase II study.

Newman E, Potmesil M, Ryan T, Marcus S, Hiotis S, Yee H, Norwood B, Wendell M, Muggia F, Hochster H.

Semin Oncol. 2005 Dec;32(6 Suppl 9):S97-100.PMID: 16399443 [PubMed - indexed for MEDLINE]Related articles

Phase I/II dose-escalation study of pemetrexed plus irinotecan in patients with advanced colorectal cancer.

Hochster H, Kettner E, Kroning H, Becker K, Lordick F, Ramanathan RK, Macdonald J, Hong S, John W, Schmoll HJ.

Clin Colorectal Cancer. 2005 Nov;5(4):257-62.PMID: 16356302 [PubMed - indexed for MEDLINE]Related articles

Prolonged topotecan infusion with cisplatin in the first-line treatment of ovarian cancer: an NYGOG and ECOG study.

Hochster HS, Plimack ER, Mandeli J, Wadler S, Runowicz C, Goldberg G, Speyer J, Wallach R, Muggia F; New York Gynecologic Oncology Group (and phase II consortium) and the Eastern Cooperative Oncology.

Gynecol Oncol. 2006 Feb;100(2):324-9. Epub 2005 Oct 25.PMID: 16253316 [PubMed - indexed for MEDLINE]Related articles

Capecitabine plus oxaliplatin vs infusional 5-fluorouracil plus oxaliplatin in the treatment of colorectal cancer. Con: Pumpin' FU (or, avoiding that oral fixation).

Hochster HS.

Clin Adv Hematol Oncol. 2005 May;3(5):405-6. No abstract available. PMID: 16167014 [PubMed - indexed for MEDLINE]Related articles

Phase I study of combined pegylated liposomal doxorubicin with protracted daily topotecan for ovarian cancer.

Mirchandani D, Hochster H, Hamilton A, Liebes L, Yee H, Curtin JP, Lee S, Sorich J, Dellenbaugh C, Muggia FM.

Clin Cancer Res. 2005 Aug 15;11(16):5912-9.PMID: 16115933 [PubMed - indexed for MEDLINE]Related articlesFree article

Recent developments in the clinical activity of topoisomerase-1 inhibitors.

Kreditor M, Fink M, Hochster HS.

Cancer Chemother Biol Response Modif. 2005;22:61-100. Review. No abstract available. PMID: 16110608 [PubMed - indexed for MEDLINE]Related articles

Assessment of infusional 5-fluorouracil schedule and dose intensity: a Southwest Oncology Group and Eastern Cooperative Oncology Group study.

Leichman CG, Benedetti JK, Zalupski MM, Hochster H, Shields AF, Lenz HJ, Wade Iii JL, Bearden Iii JD, Macdonald JS.

Clin Colorectal Cancer. 2005 Jul;5(2):119-23.PMID: 16098253 [PubMed - indexed for MEDLINE]Related articles

Randomized multicenter phase II trial of bolus plus infusional fluorouracil/leucovorin compared with fluorouracil/leucovorin plus oxaliplatin as third-line treatment of patients with advanced colorectal cancer.

Kemeny N, Garay CA, Gurtler J, Hochster H, Kennedy P, Benson A, Brandt DS, Polikoff J, Wertheim M, Shumaker G, Hallman D, Burger B, Gupta S.

J Clin Oncol. 2004 Dec 1;22(23):4753-61. Erratum in: J Clin Oncol. 2005 Jan 1;23(1):248. PMID: 15570076 [PubMed - indexed for MEDLINE]Related articles

The role of pemetrexed in the treatment of gastrointestinal malignancy.

Hochster HS.

Clin Colorectal Cancer. 2004 Sep;4(3):190-5. Review.PMID: 15377402 [PubMed - indexed for MEDLINE]Related articles

Oxaliplatin: practical guidelines for administration.

Sorich J, Taubes B, Wagner A, Hochster H.

Clin J Oncol Nurs. 2004 Jun;8(3):251-6. Review.PMID: 15208819 [PubMed - indexed for MEDLINE]Related articles

A phase I and pharmacokinetic study of docetaxel combined with Doxil (pegylated liposomal doxorubicin) without and with granulocyte colony stimulating factor.

Pavlick AC, Chodkiewicz C, Liebes L, Hamilton A, Wasserheit C, Hochster H, Speyer J, Phillips Z, Downey A, Sorich J, Muggia F.

Anticancer Drugs. 2004 Feb;15(2):119-25.PMID: 15075667 [PubMed - indexed for MEDLINE]Related articles

Phase I clinical and pharmacokinetic study of BMS-247550, a novel derivative of epothilone B, in solid tumors.

Mani S, McDaid H, Hamilton A, Hochster H, Cohen MB, Khabelle D, Griffin T, Lebwohl DE, Liebes L, Muggia F, Horwitz SB.

Clin Cancer Res. 2004 Feb 15;10(4):1289-98.PMID: 14977827 [PubMed - indexed for MEDLINE]Related articlesFree article

Biweekly 72-hour 9-aminocamptothecin infusion as second-line therapy for ovarian carcinoma: phase II study of the New York Gynecologic Oncology Group and the Eastern Cooperative Oncology Group.

Hochster H, Plimack ER, Runowicz CD, Speyer J, Wallach RC, Sorich J, Mandeli J, Wadler S, Wright J, Muggia FM.

J Clin Oncol. 2004 Jan 1;22(1):120-6.PMID: 14701774 [PubMed - indexed for MEDLINE]Related articles

Phase I clinical study of infusional 5-fluorouracil with oxaliplatin and gemcitabine (FOG regimen) in patients with solid tumors.

Goel S, Bulgaru A, Hochster H, Wadler S, Zamboni W, Egorin M, Ivy P, Leibes L, Muggia F, Lockwood G, Harvey E, Renshaw G, Mani S.

Ann Oncol. 2003 Nov;14(11):1682-7.PMID: 14581279 [PubMed - indexed for MEDLINE]Related articlesFree article

Opportunities for newer agents in combination with oxaliplatin.

Hochster HS.

Semin Oncol. 2003 Aug;30(4 Suppl 15):62-7. Review.PMID: 14523797 [PubMed - indexed for MEDLINE]Related articles

Randomized phase II comparison of dose-intense gemcitabine: thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma.

Tempero M, Plunkett W, Ruiz Van Haperen V, Hainsworth J, Hochster H, Lenzi R, Abbruzzese J.

J Clin Oncol. 2003 Sep 15;21(18):3402-8. Epub 2003 Jul 28.PMID: 12885837 [PubMed - indexed for MEDLINE]Related articles

Oxaliplatin with weekly bolus fluorouracil and low-dose leucovorin as first-line therapy for patients with colorectal cancer.

Hochster H, Chachoua A, Speyer J, Escalon J, Zeleniuch-Jacquotte A, Muggia F.

J Clin Oncol. 2003 Jul 15;21(14):2703-7.PMID: 12860947 [PubMed - indexed for MEDLINE]Related articles

Newer approaches to gemcitabine-based therapy of pancreatic cancer: fixed-dose-rate infusion and novel agents.

Hochster HS.

Int J Radiat Oncol Biol Phys. 2003;56(4 Suppl):24-30. Review.PMID: 12826248 [PubMed - indexed for MEDLINE]Related articles

Phase I study of amifostine as a cytoprotector of the gemcitabine/cisplatin combination in patients with advanced solid malignancies.

Haigentz M Jr, Kim M, Sorich J, Lee J, Hochster H, Macapinlac M, Mirchandani D, Sewak S, Pavlick A, Volm M, Hamilton A, Muggia FM.

Anticancer Drugs. 2003 Apr;14(4):321-6.PMID: 12679737 [PubMed - indexed for MEDLINE]Related articles

The role of pemetrexed in the treatment of colorectal cancer.

Hochster H.

Semin Oncol. 2002 Dec;29(6 Suppl 18):54-6. Review.PMID: 12571812 [PubMed - indexed for MEDLINE]Related articles

Phase I and pharmacologic study of i.p. 9-aminocamptothecin given as six fractions over 14 days.

Muggia FM, Liebes L, Hazarika M, Wadler S, Hamilton A, Hornreich G, Sorich J, Chiang C, Newman E, Potmesil M, Hochster H.

Anticancer Drugs. 2002 Sep;13(8):819-25.PMID: 12394266 [PubMed - indexed for MEDLINE]Related articles

Neoadjuvant chemotherapy with CPT-11 and cisplatin downstages locally advanced gastric cancer.

Newman E, Marcus SG, Potmesil M, Sewak S, Yee H, Sorich J, Hayek M, Muggia F, Hochster H.

J Gastrointest Surg. 2002 Mar-Apr;6(2):212-23; discussion 223.PMID: 11992807 [PubMed - indexed for MEDLINE]Related articles

Activity and safety of vinorelbine combined with doxorubicin or fluorouracil as first-line therapy in advanced breast cancer: a stratified phase II study.

Hochster HS, Vogel CL, Burman SL, White R.

Oncologist. 2001;6(3):269-77.PMID: 11423674 [PubMed - indexed for MEDLINE]Related articlesFree article

High-performance liquid chromatography-based determination of total isothiocyanate levels in human plasma: application to studies with 2-phenethyl isothiocyanate.

Liebes L, Conaway CC, Hochster H, Mendoza S, Hecht SS, Crowell J, Chung FL.

Anal Biochem. 2001 Apr 15;291(2):279-89.PMID: 11401302 [PubMed - indexed for MEDLINE]Related articles