PubMed

Pharmacological targeting of native CatSper channels reveals a required role in maintenance of sperm hyperactivation.

Carlson AE, Burnett LA, del Camino D, Quill TA, Hille B, Chong JA, Moran MM, Babcock DF.

PLoS One. 2009 Aug 31;4(8):e6844.PMID: 19718436 [PubMed - in process]Related articlesFree article

Fluorescence changes reveal kinetic steps of muscarinic receptor-mediated modulation of phosphoinositides and Kv7.2/7.3 K+ channels.

Jensen JB, Lyssand JS, Hague C, Hille B.

J Gen Physiol. 2009 Apr;133(4):347-59.PMID: 19332618 [PubMed - in process]Related articlesFree article

Control of granule mobility and exocytosis by Ca2+ -dependent formation of F-actin in pancreatic duct epithelial cells.

Jung SR, Kim MH, Hille B, Koh DS.

Traffic. 2009 Apr;10(4):392-410. Epub 2009 Jan 24.PMID: 19192247 [PubMed - indexed for MEDLINE]Related articles

Tissue-specific PKA inhibition using a chemical genetic approach and its application to studies on sperm capacitation.

Morgan DJ, Weisenhaus M, Shum S, Su T, Zheng R, Zhang C, Shokat KM, Hille B, Babcock DF, McKnight GS.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20740-5. Epub 2008 Dec 12.PMID: 19074277 [PubMed - indexed for MEDLINE]Related articlesFree article

Glutamate transporter-mediated glutamate secretion in the mammalian pineal gland.

Kim MH, Uehara S, Muroyama A, Hille B, Moriyama Y, Koh DS.

J Neurosci. 2008 Oct 22;28(43):10852-63.PMID: 18945893 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional stoichiometry of the unitary calcium-release-activated calcium channel.

Ji W, Xu P, Li Z, Lu J, Liu L, Zhan Y, Chen Y, Hille B, Xu T, Chen L.

Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13668-73. Epub 2008 Aug 29.PMID: 18757751 [PubMed - indexed for MEDLINE]Related articlesFree article

PIP2 is a necessary cofactor for ion channel function: how and why?

Suh BC, Hille B.

Annu Rev Biophys. 2008;37:175-95. Review.PMID: 18573078 [PubMed - indexed for MEDLINE]Related articlesFree article

Protease-activated receptor-2 increases exocytosis via multiple signal transduction pathways in pancreatic duct epithelial cells.

Kim MH, Choi BH, Jung SR, Sernka TJ, Kim S, Kim KT, Hille B, Nguyen TD, Koh DS.

J Biol Chem. 2008 Jul 4;283(27):18711-20. Epub 2008 Apr 30.PMID: 18448425 [PubMed - indexed for MEDLINE]Related articlesFree article

Calcium transport mechanisms of PC12 cells.

Duman JG, Chen L, Hille B.

J Gen Physiol. 2008 Apr;131(4):307-23. Epub 2008 Mar 17.PMID: 18347082 [PubMed - indexed for MEDLINE]Related articlesFree article

GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current.

Lauckner JE, Jensen JB, Chen HY, Lu HC, Hille B, Mackie K.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2699-704. Epub 2008 Feb 8.PMID: 18263732 [PubMed - indexed for MEDLINE]Related articlesFree article

External Ca2+ acts upstream of adenylyl cyclase SACY in the bicarbonate signaled activation of sperm motility.

Carlson AE, Hille B, Babcock DF.

Dev Biol. 2007 Dec 1;312(1):183-92. Epub 2007 Sep 20.PMID: 17950270 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenosine and catecholamine agonists speed the flagellar beat of mammalian sperm by a non-receptor-mediated mechanism.

Schuh SM, Hille B, Babcock DF.

Biol Reprod. 2007 Dec;77(6):960-9. Epub 2007 Aug 29.PMID: 17761644 [PubMed - indexed for MEDLINE]Related articlesFree article

Electrostatic interaction of internal Mg2+ with membrane PIP2 Seen with KCNQ K+ channels.

Suh BC, Hille B.

J Gen Physiol. 2007 Sep;130(3):241-56.PMID: 17724161 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of KCNQ channels by manipulation of phosphoinositides.

Suh BC, Hille B.

J Physiol. 2007 Aug 1;582(Pt 3):911-6. Epub 2007 Apr 5.PMID: 17412763 [PubMed - indexed for MEDLINE]Related articlesFree article

Rapid chemically induced changes of PtdIns(4,5)P2 gate KCNQ ion channels.

Suh BC, Inoue T, Meyer T, Hille B.

Science. 2006 Dec 1;314(5804):1454-7. Epub 2006 Sep 21.PMID: 16990515 [PubMed - indexed for MEDLINE]Related articlesFree article

Pattern of Ca2+ increase determines the type of secretory mechanism activated in dog pancreatic duct epithelial cells.

Jung SR, Kim K, Hille B, Nguyen TD, Koh DS.

J Physiol. 2006 Oct 1;576(Pt 1):163-78. Epub 2006 Jul 20.PMID: 16857709 [PubMed - indexed for MEDLINE]Related articlesFree article

Contributions of intracellular compartments to calcium dynamics: implicating an acidic store.

Duman JG, Chen L, Palmer AE, Hille B.

Traffic. 2006 Jul;7(7):859-72.PMID: 16787398 [PubMed - indexed for MEDLINE]Related articles

Does diacylglycerol regulate KCNQ channels?

Suh BC, Hille B.

Pflugers Arch. 2006 Dec;453(3):293-301. Epub 2006 May 24.PMID: 16721610 [PubMed - indexed for MEDLINE]Related articles

The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins.

Lauckner JE, Hille B, Mackie K.

Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):19144-9. Epub 2005 Dec 19.PMID: 16365309 [PubMed - indexed for MEDLINE]Related articlesFree article

Signaling pathways for modulation of mouse sperm motility by adenosine and catecholamine agonists.

Schuh SM, Carlson AE, McKnight GS, Conti M, Hille B, Babcock DF.

Biol Reprod. 2006 Mar;74(3):492-500. Epub 2005 Nov 16.PMID: 16291925 [PubMed - in process]Related articlesFree article

Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current.

Horowitz LF, Hirdes W, Suh BC, Hilgemann DW, Mackie K, Hille B.

J Gen Physiol. 2005 Sep;126(3):243-62.PMID: 16129772 [PubMed - indexed for MEDLINE]Related articlesFree article

Identical phenotypes of CatSper1 and CatSper2 null sperm.

Carlson AE, Quill TA, Westenbroek RE, Schuh SM, Hille B, Babcock DF.

J Biol Chem. 2005 Sep 16;280(37):32238-44. Epub 2005 Jul 21.PMID: 16036917 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of ion channels by phosphatidylinositol 4,5-bisphosphate.

Suh BC, Hille B.

Curr Opin Neurobiol. 2005 Jun;15(3):370-8. Review.PMID: 15922587 [PubMed - indexed for MEDLINE]Related articles

Muscarinic modulation of erg potassium current.

Hirdes W, Horowitz LF, Hille B.

J Physiol. 2004 Aug 15;559(Pt 1):67-84. Epub 2004 Jul 2.PMID: 15235086 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of KCNQ2/KCNQ3 current by G protein cycling: the kinetics of receptor-mediated signaling by Gq.

Suh BC, Horowitz LF, Hirdes W, Mackie K, Hille B.

J Gen Physiol. 2004 Jun;123(6):663-83.PMID: 15173220 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased nucleotide excision repair activity and alterations of topoisomerase IIalpha are associated with the in vivo resistance of a P388 leukemia subline to F11782, a novel catalytic inhibitor of topoisomerases I and II.

Kruczynski A, Barret JM, Van Hille B, Chansard N, Astruc J, Menon Y, Duchier C, Créancier L, Hill BT.

Clin Cancer Res. 2004 May 1;10(9):3156-68.PMID: 15131057 [PubMed - indexed for MEDLINE]Related articlesFree article

Simplification of rat intubation on inclined metal plate.

Kastl S, Kotschenreuther U, Hille B, Schmidt J, Gepp H, Hohenberger W.

Adv Physiol Educ. 2004 Dec;28(1-4):29-32.PMID: 14973009 [PubMed - indexed for MEDLINE]Related articlesFree article

CatSper1 required for evoked Ca2+ entry and control of flagellar function in sperm.

Carlson AE, Westenbroek RE, Quill T, Ren D, Clapham DE, Hille B, Garbers DL, Babcock DF.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14864-8. Epub 2003 Dec 1.PMID: 14657352 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of exocytosis by purinergic receptors in pancreatic duct epithelial cells.

Jung SR, Kim MH, Hille B, Nguyen TD, Koh DS.

Am J Physiol Cell Physiol. 2004 Mar;286(3):C573-9. Epub 2003 Nov 5.PMID: 14602582 [PubMed - indexed for MEDLINE]Related articlesFree article

Calcium clearance mechanisms of mouse sperm.

Wennemuth G, Babcock DF, Hille B.

J Gen Physiol. 2003 Jul;122(1):115-28. Erratum in: J Gen Physiol. 2003 Sep;122(3):375. PMID: 12835474 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynamics of calcium clearance in mouse pancreatic beta-cells.

Chen L, Koh DS, Hille B.

Diabetes. 2003 Jul;52(7):1723-31.PMID: 12829639 [PubMed - indexed for MEDLINE]Related articlesFree article

Sensitization of regulated exocytosis by protein kinase C.

Zhu H, Hille B, Xu T.

Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):17055-9. Epub 2002 Dec 16.PMID: 12486252 [PubMed - indexed for MEDLINE]Related articlesFree article

Antibodies and a cysteine-modifying reagent show correspondence of M current in neurons to KCNQ2 and KCNQ3 K+ channels.

Roche JP, Westenbroek R, Sorom AJ, Hille B, Mackie K, Shapiro MS.

Br J Pharmacol. 2002 Dec;137(8):1173-86.PMID: 12466226 [PubMed - indexed for MEDLINE]Related articlesFree article

Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis.

Suh BC, Hille B.

Neuron. 2002 Aug 1;35(3):507-20.PMID: 12165472 [PubMed - indexed for MEDLINE]Related articles

Identification of subtypes of muscarinic receptors that regulate Ca2+ and K+ channel activity in sympathetic neurons.

Shapiro MS, Gomeza J, Hamilton SE, Hille B, Loose MD, Nathanson NM, Roche JP, Wess J.

Life Sci. 2001 Apr 27;68(22-23):2481-7.PMID: 11392616 [PubMed - indexed for MEDLINE]Related articles

Characterization of the biological and biochemical activities of F 11782 and the bisdioxopiperazines, ICRF-187 and ICRF-193, two types of topoisomerase II catalytic inhibitors with distinctive mechanisms of action.

van Hille B, Etiévant C, Barret JM, Kruczynski A, Hill BT.

Anticancer Drugs. 2000 Nov;11(10):829-41.PMID: 11142691 [PubMed - indexed for MEDLINE]Related articles

Expression in yeast and purification of functional recombinant human poly(ADP-ribose)polymerase (PARP). Comparative pharmacological profile with that of the rat enzyme.

Perrin D, Gras S, van Hille B, Hill BT.

J Enzyme Inhib. 2000;15(5):461-9.PMID: 11030086 [PubMed - indexed for MEDLINE]Related articles

Loading of oxidizable transmitters into secretory vesicles permits carbon-fiber amperometry.

Kim KT, Koh DS, Hille B.

J Neurosci. 2000 Oct 15;20(20):RC101.PMID: 11027252 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of exocytosis by protein kinases and Ca(2+) in pancreatic duct epithelial cells.

Koh DS, Moody MW, Nguyen TD, Hille B.

J Gen Physiol. 2000 Oct;116(4):507-20.PMID: 11004201 [PubMed - indexed for MEDLINE]Related articlesFree article

F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103.

Etiévant C, Kruczynski A, Barret JM, Perrin D, van Hille B, Guminski Y, Hill BT.

Cancer Chemother Pharmacol. 2000;46(2):101-13.PMID: 10972479 [PubMed - indexed for MEDLINE]Related articles

Differential in vitro interactions of a series of clinically useful topoisomerase-interacting compounds with the cleavage/religation activity of the human topoisomerase IIalpha and IIbeta isoforms.

van Hille B, Perrin D, Hill BT.

Anticancer Drugs. 1999 Jul;10(6):551-60.PMID: 10885903 [PubMed - indexed for MEDLINE]Related articles

Mitochondria shape hormonally induced cytoplasmic calcium oscillations and modulate exocytosis.

Kaftan EJ, Xu T, Abercrombie RF, Hille B.

J Biol Chem. 2000 Aug 18;275(33):25465-70.PMID: 10835418 [PubMed - indexed for MEDLINE]Related articlesFree article

CaV2.2 and CaV2.3 (N- and R-type) Ca2+ channels in depolarization-evoked entry of Ca2+ into mouse sperm.

Wennemuth G, Westenbroek RE, Xu T, Hille B, Babcock DF.

J Biol Chem. 2000 Jul 14;275(28):21210-7.PMID: 10791962 [PubMed - indexed for MEDLINE]Related articlesFree article

F 11782, a novel epipodophylloid non-intercalating dual catalytic inhibitor of topoisomerases I and II with an original mechanism of action.

Perrin D, van Hille B, Barret JM, Kruczynski A, Etiévant C, Imbert T, Hill BT.

Biochem Pharmacol. 2000 Apr 1;59(7):807-19.PMID: 10718339 [PubMed - indexed for MEDLINE]Related articles

Reconstitution of muscarinic modulation of the KCNQ2/KCNQ3 K(+) channels that underlie the neuronal M current.

Shapiro MS, Roche JP, Kaftan EJ, Cruzblanca H, Mackie K, Hille B.

J Neurosci. 2000 Mar 1;20(5):1710-21.PMID: 10684873 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential expression of topoisomerase I and RAD52 protein in yeast reveals new facets of the mechanism of action of bisdioxopiperazine compounds.

van Hille B, Clerc X, Creighton AM, Hill BT.

Br J Cancer. 1999 Nov;81(5):800-7.PMID: 10555749 [PubMed - indexed for MEDLINE]Related articlesFree article

Distribution and function of angiotensin II receptors in mouse spermatozoa.

Wennemuth G, Babcock DF, Hille B.

Andrologia. 1999 Sep;31(5):323-5.PMID: 10526652 [PubMed - indexed for MEDLINE]Related articles

Stimulation of exocytosis without a calcium signal.

Hille B, Billiard J, Babcock DF, Nguyen T, Koh DS.

J Physiol. 1999 Oct 1;520 Pt 1:23-31. Review.PMID: 10517797 [PubMed - indexed for MEDLINE]Related articlesFree article

Ion channels: from idea to reality.

Hille B, Armstrong CM, MacKinnon R.

Nat Med. 1999 Oct;5(10):1105-9. No abstract available. PMID: 10502800 [PubMed - indexed for MEDLINE]Related articles

Assignment of muscarinic receptor subtypes mediating G-protein modulation of Ca(2+) channels by using knockout mice.

Shapiro MS, Loose MD, Hamilton SE, Nathanson NM, Gomeza J, Wess J, Hille B.

Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10899-904.PMID: 10485923 [PubMed - indexed for MEDLINE]Related articlesFree article