PubMed

Weight loss with liraglutide, a once-daily human glucagon-like peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue.

Jendle J, Nauck MA, Matthews DR, Frid A, Hermansen K, Düring M, Zdravkovic M, Strauss BJ, Garber AJ; LEAD-2 and LEAD-3 Study Groups.

Diabetes Obes Metab. 2009 Dec;11(12):1163-72.PMID: 19930006 [PubMed - in process]

Observational, open-label study of type 1 and type 2 diabetes patients switching from human insulin to insulin analogue basal-bolus regimens: insights from the PREDICTIVE study.

Hermansen K, Dornhorst A, Sreenan S.

Curr Med Res Opin. 2009 Nov;25(11):2601-8.PMID: 19739940 [PubMed - in process]Related articles

An NMR-based metabonomic investigation on effects of supplementation with isosteviol or soy protein to diabetic KKAy mice.

Bertram HC, Jeppesen PB, Hermansen K.

Diabetes Obes Metab. 2009 Oct;11(10):992-5. Epub 2009 Jun 25. No abstract available. PMID: 19558611 [PubMed - in process]Related articles

Acute effects of casein on postprandial lipemia and incretin responses in type 2 diabetic subjects.

Brader L, Holm L, Mortensen L, Thomsen C, Astrup A, Holst JJ, de Vrese M, Schrezenmeir J, Hermansen K.

Nutr Metab Cardiovasc Dis. 2009 May 25. [Epub ahead of print]PMID: 19473824 [PubMed - as supplied by publisher]Related articles

Differential effects of protein quality on postprandial lipemia in response to a fat-rich meal in type 2 diabetes: comparison of whey, casein, gluten, and cod protein.

Mortensen LS, Hartvigsen ML, Brader LJ, Astrup A, Schrezenmeir J, Holst JJ, Thomsen C, Hermansen K.

Am J Clin Nutr. 2009 Jul;90(1):41-8. Epub 2009 May 20.PMID: 19458012 [PubMed - indexed for MEDLINE]Related articles

Dose- and Glucose-Dependent Effects of Amino Acids on Insulin Secretion from Isolated Mouse Islets and Clonal INS-1E Beta-Cells.

Liu Z, Jeppesen PB, Gregersen S, Chen X, Hermansen K.

Rev Diabet Stud. 2008 Winter;5(4):232-44. Epub 2009 Feb 10.PMID: 19290384 [PubMed - in process]Related articles

Effects of elevated fatty acid and glucose concentrations on pancreatic islet function in vitro.

Hong J, Jeppesen PB, Hermansen K.

Diabetes Obes Metab. 2009 Apr;11(4):397-404.PMID: 19267716 [PubMed - in process]Related articles

Comparison of 3 ad libitum diets for weight-loss maintenance, risk of cardiovascular disease, and diabetes: a 6-mo randomized, controlled trial.

Due A, Larsen TM, Mu H, Hermansen K, Stender S, Astrup A.

Am J Clin Nutr. 2008 Nov;88(5):1232-41.PMID: 18996857 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 study.

Nauck M, Frid A, Hermansen K, Shah NS, Tankova T, Mitha IH, Zdravkovic M, Düring M, Matthews DR; LEAD-2 Study Group.

Diabetes Care. 2009 Jan;32(1):84-90. Epub 2008 Oct 17.PMID: 18931095 [PubMed - in process]Related articlesFree article

Combining insulins with oral antidiabetic agents: effect on hyperglycemic control, markers of cardiovascular risk and disease.

Hermansen K, Mortensen LS, Hermansen ML.

Vasc Health Risk Manag. 2008;4(3):561-74. Review.PMID: 18827907 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased insulin sensitivity and changes in the expression profile of key insulin regulatory genes and beta cell transcription factors in diabetic KKAy-mice after feeding with a soy bean protein rich diet high in isoflavone content.

Nordentoft I, Jeppesen PB, Hong J, Abudula R, Hermansen K.

J Agric Food Chem. 2008 Jun 25;56(12):4377-85. Epub 2008 Jun 4.PMID: 18522411 [PubMed - indexed for MEDLINE]Related articles

Rebaudioside A directly stimulates insulin secretion from pancreatic beta cells: a glucose-dependent action via inhibition of ATP-sensitive K-channels.

Abudula R, Matchkov VV, Jeppesen PB, Nilsson H, Aalkjaer C, Hermansen K.

Diabetes Obes Metab. 2008 Nov;10(11):1074-85. Epub 2008 Apr 22.PMID: 18435771 [PubMed - indexed for MEDLINE]Related articles

[Health economic consequences of insulin analogues in the treatment of type 1 diabetes in Denmark]

Palmer AJ, Lammert M, Hermansen K.

Ugeskr Laeger. 2008 Apr 7;170(15):1250-4. Danish. PMID: 18433583 [PubMed - indexed for MEDLINE]Related articles

Comparison of the effects on insulin resistance and glucose tolerance of 6-mo high-monounsaturated-fat, low-fat, and control diets.

Due A, Larsen TM, Hermansen K, Stender S, Holst JJ, Toubro S, Martinussen T, Astrup A.

Am J Clin Nutr. 2008 Apr;87(4):855-62.PMID: 18400707 [PubMed - indexed for MEDLINE]Related articlesFree article

Isosteviol increases insulin sensitivity and changes gene expression of key insulin regulatory genes and transcription factors in islets of the diabetic KKAy mouse.

Nordentoft I, Jeppesen PB, Hong J, Abudula R, Hermansen K.

Diabetes Obes Metab. 2008 Sep;10(10):939-49. Epub 2008 Jan 14.PMID: 18201205 [PubMed - indexed for MEDLINE]Related articles

Expression Analysis of cPLA2 Alpha Interacting TIP60 in Diabetic KKAy and Non-Diabetic C57BL Wild-Type Mice: No Impact of Transient and Stable TIP60 Overexpression on Glucose-Stimulated Insulin Secretion in Pancreatic Beta-Cells.

Nordentoft I, Jeppesen PB, Nielsen AL, Jorgensen P, Hermansen K.

Rev Diabet Stud. 2007 Fall;4(3):147-58. Epub 2007 Nov 10.PMID: 18084672 [PubMed - in process]Related articlesFree article

Bodyweight changes associated with antihyperglycaemic agents in type 2 diabetes mellitus.

Hermansen K, Mortensen LS.

Drug Saf. 2007;30(12):1127-42. Review.PMID: 18035865 [PubMed - indexed for MEDLINE]Related articles

[Alcohol and lifestyle diseases]

Hermansen K, Jørgensen K, Schmidt EB, Tjønneland A, Tolstrup JS, Grønbaek MN.

Ugeskr Laeger. 2007 Oct 1;169(40):3404-6. Danish. PMID: 17953867 [PubMed - indexed for MEDLINE]Related articles

3-Month Results from Denmark within the Globally Prospective and Observational Study to Evaluate Insulin Detemir Treatment in Type 1 and Type 2 Diabetes: The PREDICTIVE Study.

Hermansen K, Lund P, Clemmensen K, Breum L, Kleis Moller M, Mette Rosenfalck A, Christiansen E; on behalf of the Danish PREDICTIVE study group.

Rev Diabet Stud. 2007 Summer;4(2):89-97. Epub 2007 Aug 10.PMID: 17823693 [PubMed - in process]Related articlesFree article

Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, in patients with type 2 diabetes mellitus inadequately controlled on glimepiride alone or on glimepiride and metformin.

Hermansen K, Kipnes M, Luo E, Fanurik D, Khatami H, Stein P; Sitagliptin Study 035 Group.

Diabetes Obes Metab. 2007 Sep;9(5):733-45. Epub 2007 Jun 26.PMID: 17593236 [PubMed - indexed for MEDLINE]Related articles

Differential postprandial lipoprotein responses in type 2 diabetic men with and without clinical evidence of a former myocardial infarction.

Carstensen M, Thomsen C, Gotzsche O, Holst JJ, Schrezenmeir J, Hermansen K.

Rev Diabet Stud. 2004 Winter;1(4):175-84. Epub 2005 Feb 10.PMID: 17491702 [PubMed]Related articlesFree article

High-fat feeding during gestation and nursing period have differential effects on the insulin secretory capacity in offspring from normal Wistar rats.

Dyrskog SE, Gregersen S, Hermansen K.

Rev Diabet Stud. 2005 Fall;2(3):136-45. Epub 2005 Nov 10.PMID: 17491688 [PubMed]Related articlesFree article

The diterpene glycoside, rebaudioside A, does not improve glycemic control or affect blood pressure after eight weeks treatment in the Goto-Kakizaki rat.

Dyrskog SE, Jeppesen PB, Chen J, Christensen LP, Hermansen K.

Rev Diabet Stud. 2005 Summer;2(2):84-91. Epub 2005 Aug 10.PMID: 17491683 [PubMed]Related articlesFree article

Can stevioside in combination with a soy-based dietary supplement be a new useful treatment of type 2 diabetes? An in vivo study in the diabetic goto-kakizaki rat.

Jeppesen PB, Dyrskog SE, Agger A, Gregersen S, Colombo M, Xiao J, Hermansen K.

Rev Diabet Stud. 2006 Winter;3(4):189-99. Epub 2007 Feb 10.PMID: 17487343 [PubMed - in process]Related articlesFree article

Stevioside Counteracts Beta-Cell Lipotoxicity without Affecting Acetyl CoA Carboxylase.

Chen J, Jeppesen PB, Nordentoft I, Hermansen K.

Rev Diabet Stud. 2006 Winter;3(4):178-88. Epub 2007 Feb 10.PMID: 17487342 [PubMed - in process]Related articlesFree article

Can the Glycemic Index (GI) be used as a tool in the prevention and management of Type 2 diabetes?

Hermansen ML, Eriksen NM, Mortensen LS, Holm L, Hermansen K.

Rev Diabet Stud. 2006 Summer;3(2):61-71. Epub 2006 Aug 10.PMID: 17487328 [PubMed]Related articlesFree article

Does insulin detemir have a role in reducing risk of insulin-associated weight gain?

Hermansen K, Davies M.

Diabetes Obes Metab. 2007 May;9(3):209-17. Review.PMID: 17391147 [PubMed - indexed for MEDLINE]Related articles

Low-intensity training dissociates metabolic from aerobic fitness.

Helge JW, Damsgaard R, Overgaard K, Andersen JL, Donsmark M, Dyrskog SE, Hermansen K, Saltin B, Daugaard JR.

Scand J Med Sci Sports. 2008 Feb;18(1):86-94. Epub 2007 Mar 12.PMID: 17355324 [PubMed - indexed for MEDLINE]Related articles

Stevioside improves pancreatic beta-cell function during glucotoxicity via regulation of acetyl-CoA carboxylase.

Chen J, Jeppesen PB, Nordentoft I, Hermansen K.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1906-16. Epub 2007 Mar 6.PMID: 17341549 [PubMed - indexed for MEDLINE]Related articlesFree article

The G-250A polymorphism in the hepatic lipase gene promoter is associated with changes in hepatic lipase activity and LDL cholesterol: The KANWU Study.

Lindi V, Schwab U, Louheranta A, Vessby B, Hermansen K, Tapsell L, Riccardi G, Rivellese AA, Laakso M, Uusitupa MI; KANWU Study Group.

Nutr Metab Cardiovasc Dis. 2008 Feb;18(2):88-95. Epub 2007 Feb 26.PMID: 17327141 [PubMed - indexed for MEDLINE]Related articles

Comparison of insulin responses in experiments using pooled mice islets versus islets from individual animals in the study of diabetes.

Dyrskog SE, Erlandsen M, Chen J, Hong J, Abudula R, Hermansen K.

Metabolism. 2007 Mar;56(3):304-7.PMID: 17292716 [PubMed - indexed for MEDLINE]Related articles

Efficacy of indapamide SR compared with enalapril in elderly hypertensive patients with type 2 diabetes.

Puig JG, Marre M, Kokot F, Fernandez M, Jermendy G, Opie L, Moyseev V, Scheen A, Ionescu-Tirgoviste C, Saldanha MH, Halabe A, Williams B, Mion D Jr, Ruiz M, Hermansen K, Tuomilehto J, Finizola B, Gallois Y, Amouyel P, Ollivier JP, Asmar R.

Am J Hypertens. 2007 Jan;20(1):90-7.PMID: 17198918 [PubMed - indexed for MEDLINE]Related articles

Stevioside counteracts the glyburide-induced desensitization of the pancreatic beta-cell function in mice: studies in vitro.

Chen J, Jeppesen PB, Nordentoft I, Hermansen K.

Metabolism. 2006 Dec;55(12):1674-80.PMID: 17142143 [PubMed - indexed for MEDLINE]Related articles

Fish oil, insulin sensitivity, insulin secretion and glucose tolerance in healthy people: is there any effect of fish oil supplementation in relation to the type of background diet and habitual dietary intake of n-6 and n-3 fatty acids?

Giacco R, Cuomo V, Vessby B, Uusitupa M, Hermansen K, Meyer BJ, Riccardi G, Rivellese AA; KANWU Study Group.

Nutr Metab Cardiovasc Dis. 2007 Oct;17(8):572-80. Epub 2006 Nov 28.PMID: 17127043 [PubMed - indexed for MEDLINE]Related articles

Fatty acid-induced effect on glucagon secretion is mediated via fatty acid oxidation.

Hong J, Jeppesen PB, Nordentoft I, Hermansen K.

Diabetes Metab Res Rev. 2007 Mar;23(3):202-10.PMID: 16802400 [PubMed - indexed for MEDLINE]Related articles

A 26-week, randomized, parallel, treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucose-lowering drugs in insulin-naive people with type 2 diabetes.

Hermansen K, Davies M, Derezinski T, Martinez Ravn G, Clauson P, Home P.

Diabetes Care. 2006 Jun;29(6):1269-74. Erratum in: Diabetes Care. 2007 Apr;30(4):1035. PMID: 16732007 [PubMed - indexed for MEDLINE]Related articlesFree article

Dietary (n-3) fatty acids reduce plasma F2-isoprostanes but not prostaglandin F2alpha in healthy humans.

Nälsén C, Vessby B, Berglund L, Uusitupa M, Hermansen K, Riccardi G, Rivellese A, Storlien L, Erkkilä A, Ylä-Herttuala S, Tapsell L, Basu S.

J Nutr. 2006 May;136(5):1222-8.PMID: 16614408 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of dietary saturated, monounsaturated, and n-3 fatty acids on blood pressure in healthy subjects.

Rasmussen BM, Vessby B, Uusitupa M, Berglund L, Pedersen E, Riccardi G, Rivellese AA, Tapsell L, Hermansen K; KANWU Study Group.

Am J Clin Nutr. 2006 Feb;83(2):221-6.PMID: 16469978 [PubMed - indexed for MEDLINE]Related articlesFree article

Repeated prolonged whole-body low-intensity exercise: effects on insulin sensitivity and limb muscle adaptations.

Helge JW, Overgaard K, Damsgaard R, Sørensen K, Andersen JL, Dyrskog SE, Hermansen K, Saltin B, Wojtaszewski JF.

Metabolism. 2006 Feb;55(2):217-23.PMID: 16423629 [PubMed - indexed for MEDLINE]Related articles

Energy restriction prevents the development of type 2 diabetes in Zucker diabetic fatty rats: coordinated patterns of gene expression for energy metabolism in insulin-sensitive tissues and pancreatic islets determined by oligonucleotide microarray analysis.

Colombo M, Kruhoeffer M, Gregersen S, Agger A, Jeppesen P, Oerntoft T, Hermansen K.

Metabolism. 2006 Jan;55(1):43-52.PMID: 16324918 [PubMed - indexed for MEDLINE]Related articles

Prevention of hyperglycemia in Zucker diabetic fatty rats by exercise training: effects on gene expression in insulin-sensitive tissues determined by high-density oligonucleotide microarray analysis.

Colombo M, Gregersen S, Kruhoeffer M, Agger A, Xiao J, Jeppesen PB, Orntoft T, Ploug T, Galbo H, Hermansen K.

Metabolism. 2005 Dec;54(12):1571-81.PMID: 16311088 [PubMed - indexed for MEDLINE]Related articles

Stevioside does not cause increased basal insulin secretion or beta-cell desensitization as does the sulphonylurea, glibenclamide: studies in vitro.

Chen J, Jeppesen PB, Abudula R, Dyrskog SE, Colombo M, Hermansen K.

Life Sci. 2006 Mar 6;78(15):1748-53. Epub 2005 Nov 2.PMID: 16260001 [PubMed - indexed for MEDLINE]Related articles

Stevioside counteracts the alpha-cell hypersecretion caused by long-term palmitate exposure.

Hong J, Chen L, Jeppesen PB, Nordentoft I, Hermansen K.

Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E416-22. Epub 2005 Oct 4.PMID: 16204336 [PubMed - indexed for MEDLINE]Related articlesFree article

The short-term effect of fatty acids on glucagon secretion is influenced by their chain length, spatial configuration, and degree of unsaturation: studies in vitro.

Hong J, Abudula R, Chen J, Jeppesen PB, Dyrskog SE, Xiao J, Colombo M, Hermansen K.

Metabolism. 2005 Oct;54(10):1329-36.PMID: 16154432 [PubMed - indexed for MEDLINE]Related articles

Comparison of a high saturated fat diet with a high carbohydrate diet during pregnancy and lactation: effects on insulin sensitivity in offspring of rats.

Gregersen S, Dyrskog SE, Storlien LH, Hermansen K.

Metabolism. 2005 Oct;54(10):1316-22.PMID: 16154430 [PubMed - indexed for MEDLINE]Related articles

Preventive effects of a soy-based diet supplemented with stevioside on the development of the metabolic syndrome and type 2 diabetes in Zucker diabetic fatty rats.

Dyrskog SE, Jeppesen PB, Colombo M, Abudula R, Hermansen K.

Metabolism. 2005 Sep;54(9):1181-8.PMID: 16125530 [PubMed - indexed for MEDLINE]Related articles

Effects of soy supplementation on blood lipids and arterial function in hypercholesterolaemic subjects.

Hermansen K, Hansen B, Jacobsen R, Clausen P, Dalgaard M, Dinesen B, Holst JJ, Pedersen E, Astrup A.

Eur J Clin Nutr. 2005 Jul;59(7):843-50.PMID: 15900307 [PubMed - indexed for MEDLINE]Related articles

Evidence-based nutritional approaches to the treatment and prevention of diabetes mellitus.

Mann JI, De Leeuw I, Hermansen K, Karamanos B, Karlström B, Katsilambros N, Riccardi G, Rivellese AA, Rizkalla S, Slama G, Toeller M, Uusitupa M, Vessby B; Diabetes and Nutrition Study Group (DNSG) of the European Association.

Nutr Metab Cardiovasc Dis. 2004 Dec;14(6):373-94. No abstract available. PMID: 15853122 [PubMed - indexed for MEDLINE]Related articles

[A scientific evaluation of the "alternative" food pyramid]

Richelsen B, Andersen NL, Flint A, Hermansen K, Marckmann P, Nielsen MJ, Osler M, Pedersen BK.

Ugeskr Laeger. 2005 Feb 21;167(8):927-31. Review. Danish. No abstract available. PMID: 15789852 [PubMed - indexed for MEDLINE]Related articles

Comparative evaluation of simple indices of insulin resistance.

Vaccaro O, Masulli M, Cuomo V, Rivellese AA, Uusitupa M, Vessby B, Hermansen K, Tapsell L, Riccardi G.

Metabolism. 2004 Dec;53(12):1522-6.PMID: 15562393 [PubMed - indexed for MEDLINE]Related articles