PubMed

Fluorescence in situ hybridization in the definitive diagnosis of malignant mesothelioma in effusion cytology.

Savic S, Franco N, Grilli B, de Vito Barascud A, Herzog M, Bode B, Loosli H, Spieler P, Schönegg R, Zlobec I, Clark DP, Herman JG, Bubendorf L.

Chest. 2010 Feb 5. [Epub ahead of print]PMID: 20139227 [PubMed - as supplied by publisher]Related articles

Prognostic significance of Gremlin1 (GREM1) promoter CpG island hypermethylation in clear cell renal cell carcinoma.

van Vlodrop IJ, Baldewijns MM, Smits KM, Schouten LJ, van Neste L, van Criekinge W, van Poppel H, Lerut E, Schuebel KE, Ahuja N, Herman JG, de Bruïne AP, van Engeland M.

Am J Pathol. 2010 Feb;176(2):575-84. Epub 2009 Dec 30.PMID: 20042676 [PubMed - in process]Related articles

Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanisms.

Hughes LA, van den Brandt PA, de Bruïne AP, Wouters KA, Hulsmans S, Spiertz A, Goldbohm RA, de Goeij AF, Herman JG, Weijenberg MP, van Engeland M.

PLoS One. 2009 Nov 23;4(11):e7951.PMID: 19956740 [PubMed - in process]Related articlesFree article

Enzymatic incorporation of multiple dyes for increased sensitivity in QD-FRET sensing for DNA methylation detection.

Bailey VJ, Keeley BP, Zhang Y, Ho YP, Easwaran H, Brock MV, Pelosky KL, Carraway HE, Baylin SB, Herman JG, Wang TH.

Chembiochem. 2010 Jan 4;11(1):71-4. No abstract available. PMID: 19904794 [PubMed - in process]Related articles

Progressive chromatin repression and promoter methylation of CTNNA1 associated with advanced myeloid malignancies.

Ye Y, McDevitt MA, Guo M, Zhang W, Galm O, Gore SD, Karp JE, Maciejewski JP, Kowalski J, Tsai HL, Gondek LP, Tsai HC, Wang X, Hooker C, Smith BD, Carraway HE, Herman JG.

Cancer Res. 2009 Nov 1;69(21):8482-90. Epub 2009 Oct 13.PMID: 19826047 [PubMed - indexed for MEDLINE]Related articles

A phase I dose-finding study of 5-azacytidine in combination with sodium phenylbutyrate in patients with refractory solid tumors.

Lin J, Gilbert J, Rudek MA, Zwiebel JA, Gore S, Jiemjit A, Zhao M, Baker SD, Ambinder RF, Herman JG, Donehower RC, Carducci MA.

Clin Cancer Res. 2009 Oct 1;15(19):6241-9. Epub 2009 Sep 29.PMID: 19789320 [PubMed - indexed for MEDLINE]Related articles

Lung cancer in never smokers: molecular profiles and therapeutic implications.

Rudin CM, Avila-Tang E, Harris CC, Herman JG, Hirsch FR, Pao W, Schwartz AG, Vahakangas KH, Samet JM.

Clin Cancer Res. 2009 Sep 15;15(18):5646-61.PMID: 19755392 [PubMed - in process]Related articles

DNA promoter hypermethylation of p16 and APC predicts neoplastic progression in Barrett's esophagus.

Wang JS, Guo M, Montgomery EA, Thompson RE, Cosby H, Hicks L, Wang S, Herman JG, Canto MI.

Am J Gastroenterol. 2009 Sep;104(9):2153-60. Epub 2009 Jul 7.PMID: 19584833 [PubMed - indexed for MEDLINE]Related articles

Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.

Fandy TE, Herman JG, Kerns P, Jiemjit A, Sugar EA, Choi SH, Yang AS, Aucott T, Dauses T, Odchimar-Reissig R, Licht J, McConnell MJ, Nasrallah C, Kim MK, Zhang W, Sun Y, Murgo A, Espinoza-Delgado I, Oteiza K, Owoeye I, Silverman LR, Gore SD, Carraway HE.

Blood. 2009 Sep 24;114(13):2764-73. Epub 2009 Jun 22.PMID: 19546476 [PubMed - indexed for MEDLINE]Related articles

N-Myc downstream-regulated gene 4 (NDRG4): a candidate tumor suppressor gene and potential biomarker for colorectal cancer.

Melotte V, Lentjes MH, van den Bosch SM, Hellebrekers DM, de Hoon JP, Wouters KA, Daenen KL, Partouns-Hendriks IE, Stessels F, Louwagie J, Smits KM, Weijenberg MP, Sanduleanu S, Khalid-de Bakker CA, Oort FA, Meijer GA, Jonkers DM, Herman JG, de Bruïne AP, van Engeland M.

J Natl Cancer Inst. 2009 Jul 1;101(13):916-27. Epub 2009 Jun 17.PMID: 19535783 [PubMed - indexed for MEDLINE]Related articles

GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer.

Hellebrekers DM, Lentjes MH, van den Bosch SM, Melotte V, Wouters KA, Daenen KL, Smits KM, Akiyama Y, Yuasa Y, Sanduleanu S, Khalid-de Bakker CA, Jonkers D, Weijenberg MP, Louwagie J, van Criekinge W, Carvalho B, Meijer GA, Baylin SB, Herman JG, de Bruïne AP, van Engeland M.

Clin Cancer Res. 2009 Jun 15;15(12):3990-7. Epub 2009 Jun 9.PMID: 19509152 [PubMed - indexed for MEDLINE]Related articles

MS-qFRET: a quantum dot-based method for analysis of DNA methylation.

Bailey VJ, Easwaran H, Zhang Y, Griffiths E, Belinsky SA, Herman JG, Baylin SB, Carraway HE, Wang TH.

Genome Res. 2009 Aug;19(8):1455-61. Epub 2009 May 14.PMID: 19443857 [PubMed - indexed for MEDLINE]Related articlesFree article

Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer.

Glöckner SC, Dhir M, Yi JM, McGarvey KE, Van Neste L, Louwagie J, Chan TA, Kleeberger W, de Bruïne AP, Smits KM, Khalid-de Bakker CA, Jonkers DM, Stockbrügger RW, Meijer GA, Oort FA, Iacobuzio-Donahue C, Bierau K, Herman JG, Baylin SB, Van Engeland M, Schuebel KE, Ahuja N.

Cancer Res. 2009 Jun 1;69(11):4691-9. Epub 2009 May 12.PMID: 19435926 [PubMed - indexed for MEDLINE]Related articles

Curcumin blocks CCL2-induced adhesion, motility and invasion, in part, through down-regulation of CCL2 expression and proteolytic activity.

Herman JG, Stadelman HL, Roselli CE.

Int J Oncol. 2009 May;34(5):1319-27.PMID: 19360344 [PubMed - indexed for MEDLINE]Related articles

DNA methylation analysis on a droplet-in-oil PCR array.

Zhang Y, Bailey V, Puleo CM, Easwaran H, Griffiths E, Herman JG, Baylin SB, Wang TH.

Lab Chip. 2009 Apr 21;9(8):1059-64. Epub 2009 Mar 6.PMID: 19350087 [PubMed - indexed for MEDLINE]Related articles

Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21.

Derks S, Bosch LJ, Niessen HE, Moerkerk PT, van den Bosch SM, Carvalho B, Mongera S, Voncken JW, Meijer GA, de Bruïne AP, Herman JG, van Engeland M.

Carcinogenesis. 2009 Jun;30(6):1041-8. Epub 2009 Mar 27.PMID: 19329758 [PubMed - indexed for MEDLINE]Related articles

Epigenetic dysregulation of secreted Frizzled-related proteins in multiple myeloma.

Jost E, Gezer D, Wilop S, Suzuki H, Herman JG, Osieka R, Galm O.

Cancer Lett. 2009 Aug 18;281(1):24-31. Epub 2009 Mar 18.PMID: 19299079 [PubMed - indexed for MEDLINE]Related articles

Decreased expression and promoter methylation of the menin tumor suppressor in pancreatic ductal adenocarcinoma.

Cavallari I, Silic-Benussi M, Rende F, Martines A, Fogar P, Basso D, Vella MD, Pedrazzoli S, Herman JG, Chieco-Bianchi L, Esposito G, Ciminale V, D'Agostino DM.

Genes Chromosomes Cancer. 2009 May;48(5):383-96.PMID: 19170121 [PubMed - indexed for MEDLINE]Related articles

MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events.

de Vogel S, Weijenberg MP, Herman JG, Wouters KA, de Goeij AF, van den Brandt PA, de Bruïne AP, van Engeland M.

Ann Oncol. 2009 Jul;20(7):1216-22. Epub 2009 Jan 22.PMID: 19164452 [PubMed - indexed for MEDLINE]Related articles

Cruciferous vegetable consumption and lung cancer risk: a systematic review.

Lam TK, Gallicchio L, Lindsley K, Shiels M, Hammond E, Tao XG, Chen L, Robinson KA, Caulfield LE, Herman JG, Guallar E, Alberg AJ.

Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):184-95. Review.PMID: 19124497 [PubMed - indexed for MEDLINE]Related articlesFree article

Alcohol consumption and the risk of nasopharyngeal carcinoma: a systematic review.

Chen L, Gallicchio L, Boyd-Lindsley K, Tao XG, Robinson KA, Lam TK, Herman JG, Caulfield LE, Guallar E, Alberg AJ.

Nutr Cancer. 2009;61(1):1-15. Review.PMID: 19116871 [PubMed - indexed for MEDLINE]Related articles

Promoter methylation of HIN-1 in the progression to esophageal squamous cancer.

Guo M, Ren J, Brock MV, Herman JG, Carraway HE.

Epigenetics. 2008 Nov;3(6):336-41. Epub 2008 Nov 8.PMID: 19098448 [PubMed - indexed for MEDLINE]Related articles

Pharmacoepigenomics in colorectal cancer: a step forward in predicting prognosis and treatment response.

Smits KM, Cleven AH, Weijenberg MP, Hughes LA, Herman JG, de Bruïne AP, van Engeland M.

Pharmacogenomics. 2008 Dec;9(12):1903-16. Review.PMID: 19072647 [PubMed - indexed for MEDLINE]Related articles

PcG proteins, DNA methylation, and gene repression by chromatin looping.

Tiwari VK, McGarvey KM, Licchesi JD, Ohm JE, Herman JG, Schübeler D, Baylin SB.

PLoS Biol. 2008 Dec 2;6(12):2911-27.PMID: 19053175 [PubMed - indexed for MEDLINE]Related articlesFree article

Epigenetic inactivation of galanin receptor 1 in head and neck cancer.

Misawa K, Ueda Y, Kanazawa T, Misawa Y, Jang I, Brenner JC, Ogawa T, Takebayashi S, Grenman RA, Herman JG, Mineta H, Carey TE.

Clin Cancer Res. 2008 Dec 1;14(23):7604-13.PMID: 19047085 [PubMed - indexed for MEDLINE]Related articlesFree article

Methylation-specific PCR.

Licchesi JD, Herman JG.

Methods Mol Biol. 2009;507:305-23.PMID: 18987823 [PubMed - indexed for MEDLINE]Related articles

An inactivating mutation in HDAC2 leads to dysregulation of apoptosis mediated by APAF1.

Hanigan CL, Van Engeland M, De Bruine AP, Wouters KA, Weijenberg MP, Eshleman JR, Herman JG.

Gastroenterology. 2008 Nov;135(5):1654-1664.e2. Epub 2008 Aug 7.PMID: 18834886 [PubMed - indexed for MEDLINE]Related articles

Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.

Yi JM, Tsai HC, Glöckner SC, Lin S, Ohm JE, Easwaran H, James CD, Costello JF, Riggins G, Eberhart CG, Laterra J, Vescovi AL, Ahuja N, Herman JG, Schuebel KE, Baylin SB.

Cancer Res. 2008 Oct 1;68(19):8094-103.PMID: 18829568 [PubMed - indexed for MEDLINE]Related articlesFree article

Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity.

Hegi ME, Liu L, Herman JG, Stupp R, Wick W, Weller M, Mehta MP, Gilbert MR.

J Clin Oncol. 2008 Sep 1;26(25):4189-99. Review.PMID: 18757334 [PubMed - indexed for MEDLINE]Related articles

Aberrant DNA methylation of the transcription factor C/EBPalpha in acute myelogenous leukemia.

Jost E, do O N, Wilop S, Herman JG, Osieka R, Galm O.

Leuk Res. 2009 Mar;33(3):443-9. Epub 2008 Aug 30.PMID: 18757096 [PubMed - indexed for MEDLINE]Related articles

Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia.

Dhir M, Montgomery EA, Glöckner SC, Schuebel KE, Hooker CM, Herman JG, Baylin SB, Gearhart SL, Ahuja N.

J Gastrointest Surg. 2008 Oct;12(10):1745-53. Epub 2008 Aug 21.PMID: 18716850 [PubMed - indexed for MEDLINE]Related articles

Carotenoids and the risk of developing lung cancer: a systematic review.

Gallicchio L, Boyd K, Matanoski G, Tao XG, Chen L, Lam TK, Shiels M, Hammond E, Robinson KA, Caulfield LE, Herman JG, Guallar E, Alberg AJ.

Am J Clin Nutr. 2008 Aug;88(2):372-83. Review.PMID: 18689373 [PubMed - indexed for MEDLINE]Related articlesFree article

Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells.

McGarvey KM, Van Neste L, Cope L, Ohm JE, Herman JG, Van Criekinge W, Schuebel KE, Baylin SB.

Cancer Res. 2008 Jul 15;68(14):5753-9.PMID: 18632628 [PubMed - indexed for MEDLINE]Related articlesFree article

Epigenetic inactivation of secreted Frizzled-related proteins in acute myeloid leukaemia.

Jost E, Schmid J, Wilop S, Schubert C, Suzuki H, Herman JG, Osieka R, Galm O.

Br J Haematol. 2008 Sep;142(5):745-53. Epub 2008 Jun 3.PMID: 18537968 [PubMed - indexed for MEDLINE]Related articles

Arsenic in drinking water and lung cancer: a systematic review.

Celik I, Gallicchio L, Boyd K, Lam TK, Matanoski G, Tao X, Shiels M, Hammond E, Chen L, Robinson KA, Caulfield LE, Herman JG, Guallar E, Alberg AJ.

Environ Res. 2008 Sep;108(1):48-55. Epub 2008 May 29. Review.PMID: 18511031 [PubMed - indexed for MEDLINE]Related articles

Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis.

Chan TA, Glockner S, Yi JM, Chen W, Van Neste L, Cope L, Herman JG, Velculescu V, Schuebel KE, Ahuja N, Baylin SB.

PLoS Med. 2008 May 27;5(5):e114.PMID: 18507500 [PubMed - indexed for MEDLINE]Related articlesFree article

Promoter hypermethylation of hallmark cancer genes in atypical adenomatous hyperplasia of the lung.

Licchesi JD, Westra WH, Hooker CM, Herman JG.

Clin Cancer Res. 2008 May 1;14(9):2570-8.PMID: 18451218 [PubMed - indexed for MEDLINE]Related articlesFree article

Methylation-specific PCR.

Herman JG, Baylin SB.

Curr Protoc Hum Genet. 2001 May;Chapter 10:Unit 10.6.PMID: 18428243 [PubMed - indexed for MEDLINE]Related articles

Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer.

Zhang W, Glöckner SC, Guo M, Machida EO, Wang DH, Easwaran H, Van Neste L, Herman JG, Schuebel KE, Watkins DN, Ahuja N, Baylin SB.

Cancer Res. 2008 Apr 15;68(8):2764-72. Erratum in: Cancer Res. 2008 Jul 15;68(14):6030. PMID: 18413743 [PubMed - indexed for MEDLINE]Related articlesFree article

Promoter hypermethylation in sentinel lymph nodes as a marker for breast cancer recurrence.

Carraway HE, Wang S, Blackford A, Guo M, Powers P, Jeter S, Davidson NE, Argani P, Terrell K, Herman JG, Lange JR.

Breast Cancer Res Treat. 2009 Mar;114(2):315-25. Epub 2008 Apr 11.PMID: 18404369 [PubMed - indexed for MEDLINE]Related articles

Effect of DNA methylation on identification of aggressive prostate cancer.

Alumkal JJ, Zhang Z, Humphreys EB, Bennett C, Mangold LA, Carducci MA, Partin AW, Garrett-Mayer E, DeMarzo AM, Herman JG.

Urology. 2008 Dec;72(6):1234-9. Epub 2008 Apr 2.PMID: 18387661 [PubMed - indexed for MEDLINE]Related articles

DNA methylation markers and early recurrence in stage I lung cancer.

Brock MV, Hooker CM, Ota-Machida E, Han Y, Guo M, Ames S, Glöckner S, Piantadosi S, Gabrielson E, Pridham G, Pelosky K, Belinsky SA, Yang SC, Baylin SB, Herman JG.

N Engl J Med. 2008 Mar 13;358(11):1118-28.PMID: 18337602 [PubMed - indexed for MEDLINE]Related articles

Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung.

Licchesi JD, Westra WH, Hooker CM, Machida EO, Baylin SB, Herman JG.

Carcinogenesis. 2008 May;29(5):895-904. Epub 2008 Feb 28.PMID: 18308762 [PubMed - indexed for MEDLINE]Related articlesFree article

p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage.

Jiemjit A, Fandy TE, Carraway H, Bailey KA, Baylin S, Herman JG, Gore SD.

Oncogene. 2008 Jun 5;27(25):3615-23. Epub 2008 Jan 28.PMID: 18223691 [PubMed - indexed for MEDLINE]Related articles

Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations.

Derks S, Postma C, Carvalho B, van den Bosch SM, Moerkerk PT, Herman JG, Weijenberg MP, de Bruïne AP, Meijer GA, van Engeland M.

Carcinogenesis. 2008 Feb;29(2):434-9. Epub 2007 Nov 28.PMID: 18048385 [PubMed - indexed for MEDLINE]Related articlesFree article

Transferrin reverses the anti-invasive activity of human prostate cancer cells that overexpress sema3E.

Herman JG, Meadows GG.

Int J Oncol. 2007 Nov;31(5):1267-72.PMID: 17912456 [PubMed - indexed for MEDLINE]Related articles

Evaluation of GATA-4 and GATA-5 methylation profiles in human pancreatic cancers indicate promoter methylation patterns distinct from other human tumor types.

Fu B, Guo M, Wang S, Campagna D, Luo M, Herman JG, Iacobuzio-Donahue CA.

Cancer Biol Ther. 2007 Oct;6(10):1546-52. Epub 2007 Jul 7.PMID: 17912029 [PubMed - indexed for MEDLINE]Related articles

Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.

Schuebel KE, Chen W, Cope L, Glöckner SC, Suzuki H, Yi JM, Chan TA, Van Neste L, Van Criekinge W, van den Bosch S, van Engeland M, Ting AH, Jair K, Yu W, Toyota M, Imai K, Ahuja N, Herman JG, Baylin SB.

PLoS Genet. 2007 Sep;3(9):1709-23. Epub 2007 Jul 31.PMID: 17892325 [PubMed - indexed for MEDLINE]Related articlesFree article

WNT10B functional dualism: beta-catenin/Tcf-dependent growth promotion or independent suppression with deregulated expression in cancer.

Yoshikawa H, Matsubara K, Zhou X, Okamura S, Kubo T, Murase Y, Shikauchi Y, Esteller M, Herman JG, Wei Wang X, Harris CC.

Mol Biol Cell. 2007 Nov;18(11):4292-303. Epub 2007 Aug 29.PMID: 17761539 [PubMed - indexed for MEDLINE]Related articlesFree article

Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer.

Guo M, House MG, Suzuki H, Ye Y, Brock MV, Lu F, Liu Z, Rustgi AK, Herman JG.

Int J Cancer. 2007 Sep 15;121(6):1219-26.PMID: 17534889 [PubMed - indexed for MEDLINE]Related articles