PubMed

Embryonic stem cells as a model for studying melanocyte development.

Zabierowski SE, Herlyn M.

Methods Mol Biol. 2010;584:301-16.PMID: 19907984 [PubMed - in process]Related articles

Distinct MHC gene expression patterns during progression of melanoma.

Degenhardt Y, Huang J, Greshock J, Horiates G, Nathanson K, Yang X, Herlyn M, Weber B.

Genes Chromosomes Cancer. 2009 Oct 27. [Epub ahead of print]PMID: 19862823 [PubMed - as supplied by publisher]Related articles

Placental gene transfer: transgene screening in mice for trophic effects on the placenta.

Katz AB, Keswani SG, Habli M, Lim FY, Zoltick PW, Midrio P, Kozin ED, Herlyn M, Crombleholme TM.

Am J Obstet Gynecol. 2009 Nov;201(5):499.e1-8. Epub 2009 Aug 28.PMID: 19716119 [PubMed - in process]Related articles

Active Notch1 confers a transformed phenotype to primary human melanocytes.

Pinnix CC, Lee JT, Liu ZJ, McDaid R, Balint K, Beverly LJ, Brafford PA, Xiao M, Himes B, Zabierowski SE, Yashiro-Ohtani Y, Nathanson KL, Bengston A, Pollock PM, Weeraratna AT, Nickoloff BJ, Pear WS, Capobianco AJ, Herlyn M.

Cancer Res. 2009 Jul 1;69(13):5312-20. Epub 2009 Jun 23.PMID: 19549918 [PubMed - indexed for MEDLINE]Related articles

The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes.

Yu H, McDaid R, Lee J, Possik P, Li L, Kumar SM, Elder DE, Van Belle P, Gimotty P, Guerra M, Hammond R, Nathanson KL, Dalla Palma M, Herlyn M, Xu X.

Am J Pathol. 2009 Jun;174(6):2367-77. Epub 2009 Apr 23.PMID: 19389934 [PubMed - indexed for MEDLINE]Related articles

Driving in the melanoma landscape.

Herlyn M.

Exp Dermatol. 2009 Jun;18(6):506-8. Epub 2009 Mar 29.PMID: 19366372 [PubMed - indexed for MEDLINE]Related articles

Matricellular proteins produced by melanocytes and melanomas: in search for functions.

Fukunaga-Kalabis M, Santiago-Walker A, Herlyn M.

Cancer Microenviron. 2008 Dec;1(1):93-102. Epub 2008 Mar 26.PMID: 19308688 [PubMed - in process]Related articlesFree article

Distinct patterns of DNA copy number alterations associate with BRAF mutations in melanomas and melanoma-derived cell lines.

Greshock J, Nathanson K, Medina A, Ward MR, Herlyn M, Weber BL, Zaks TZ.

Genes Chromosomes Cancer. 2009 May;48(5):419-28.PMID: 19226609 [PubMed - indexed for MEDLINE]Related articles

Melanocytes: from morphology to application.

Santiago-Walker A, Li L, Haass NK, Herlyn M.

Skin Pharmacol Physiol. 2009;22(2):114-21. Epub 2009 Feb 4.PMID: 19188759 [PubMed - indexed for MEDLINE]Related articles

Defining microenvironments within mouse models that enhance tumor aggressiveness.

Basu D, Herlyn M.

Cancer Biol Ther. 2009 Feb;8(4):380-1. Epub 2009 Mar 2. No abstract available. PMID: 19182538 [PubMed - indexed for MEDLINE]Related articles

Cancer stem cells are everywhere.

Passegué E, Rafii S, Herlyn M.

Nat Med. 2009 Jan;15(1):23. No abstract available. PMID: 19129778 [PubMed - indexed for MEDLINE]Related articles

Integrating tumor-initiating cells into the paradigm for melanoma targeted therapy.

Smalley KS, Herlyn M.

Int J Cancer. 2009 Mar 15;124(6):1245-50. Review.PMID: 19089923 [PubMed - indexed for MEDLINE]Related articles

Cracking the system: melanoma complexity demands new therapeutic approaches.

Vultur A, Herlyn M.

Pigment Cell Melanoma Res. 2009 Feb;22(1):4-5. Epub 2008 Dec 1. No abstract available. PMID: 19054340 [PubMed - indexed for MEDLINE]Related articles

A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification.

Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK.

J Clin Invest. 2008 Dec;118(12):3860-9. doi: 10.1172/JCI35012. Epub 2008 Nov 6.PMID: 19033657 [PubMed - indexed for MEDLINE]Related articlesFree article

Cleavage of MCM2 licensing protein fosters senescence in human keratinocytes.

Harada H, Nakagawa H, Takaoka M, Lee J, Herlyn M, Diehl JA, Rustgi AK.

Cell Cycle. 2008 Nov 15;7(22):3534-8. Epub 2008 Nov 18.PMID: 19001876 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelin-3 stimulates survival of goblet cells in organotypic cultures of fetal human colonic epithelium.

Kalabis J, Li G, Fukunaga-Kalabis M, Rustgi AK, Herlyn M.

Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295(6):G1182-9. Epub 2008 Oct 2.PMID: 18832450 [PubMed - indexed for MEDLINE]Related articles

CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations.

Smalley KS, Xiao M, Villanueva J, Nguyen TK, Flaherty KT, Letrero R, Van Belle P, Elder DE, Wang Y, Nathanson KL, Herlyn M.

Oncogene. 2009 Jan 8;28(1):85-94. Epub 2008 Sep 15.PMID: 18794803 [PubMed - indexed for MEDLINE]Related articles

Increased cyclin D1 expression can mediate BRAF inhibitor resistance in BRAF V600E-mutated melanomas.

Smalley KS, Lioni M, Dalla Palma M, Xiao M, Desai B, Egyhazi S, Hansson J, Wu H, King AJ, Van Belle P, Elder DE, Flaherty KT, Herlyn M, Nathanson KL.

Mol Cancer Ther. 2008 Sep;7(9):2876-83.PMID: 18790768 [PubMed - indexed for MEDLINE]Related articlesFree article

Bortezomib induces apoptosis in esophageal squamous cell carcinoma cells through activation of the p38 mitogen-activated protein kinase pathway.

Lioni M, Noma K, Snyder A, Klein-Szanto A, Diehl JA, Rustgi AK, Herlyn M, Smalley KS.

Mol Cancer Ther. 2008 Sep;7(9):2866-75.PMID: 18790767 [PubMed - indexed for MEDLINE]Related articlesFree article

Melanoma and the tumor microenvironment.

Villanueva J, Herlyn M.

Curr Oncol Rep. 2008 Sep;10(5):439-46. Review.PMID: 18706274 [PubMed - indexed for MEDLINE]Related articles

Pathology and mass mortality of Pacific oysters, Crassostrea gigas (Thunberg), in 2005 at the East Frisian coast, Germany.

Watermann BT, Herlyn M, Daehne B, Bergmann S, Meemken M, Kolodzey H.

J Fish Dis. 2008 Aug;31(8):621-30.PMID: 18700939 [PubMed - indexed for MEDLINE]Related articles

Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.

Smalley KS, Contractor R, Nguyen TK, Xiao M, Edwards R, Muthusamy V, King AJ, Flaherty KT, Bosenberg M, Herlyn M, Nathanson KL.

Cancer Res. 2008 Jul 15;68(14):5743-52.PMID: 18632627 [PubMed - indexed for MEDLINE]Related articlesFree article

Melanoma stem cells: the dark seed of melanoma.

Zabierowski SE, Herlyn M.

J Clin Oncol. 2008 Jun 10;26(17):2890-4. Review.PMID: 18539969 [PubMed - indexed for MEDLINE]Related articles

Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity.

Xie P, Williams DS, Atilla-Gokcumen GE, Milk L, Xiao M, Smalley KS, Herlyn M, Meggers E, Marmorstein R.

ACS Chem Biol. 2008 May 16;3(5):305-16.PMID: 18484710 [PubMed - indexed for MEDLINE]Related articles

Cytotoxicity of the matrix metalloproteinase-activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells.

Alfano RW, Leppla SH, Liu S, Bugge TH, Herlyn M, Smalley KS, Bromberg-White JL, Duesbery NS, Frankel AE.

Mol Cancer Ther. 2008 May;7(5):1218-26.PMID: 18483309 [PubMed - indexed for MEDLINE]Related articlesFree article

Unraveling the mysteries of IGF-1 signaling in melanoma.

Lee JT, Brafford P, Herlyn M.

J Invest Dermatol. 2008 Jun;128(6):1358-60.PMID: 18478012 [PubMed - indexed for MEDLINE]Related articlesFree article

The essential role of fibroblasts in esophageal squamous cell carcinoma-induced angiogenesis.

Noma K, Smalley KS, Lioni M, Naomoto Y, Tanaka N, El-Deiry W, King AJ, Nakagawa H, Herlyn M.

Gastroenterology. 2008 Jun;134(7):1981-93. Epub 2008 Mar 4.PMID: 18439605 [PubMed - indexed for MEDLINE]Related articlesFree article

Similar biological activities of two isostructural ruthenium and osmium complexes.

Maksimoska J, Williams DS, Atilla-Gokcumen GE, Smalley KS, Carroll PJ, Webster RD, Filippakopoulos P, Knapp S, Herlyn M, Meggers E.

Chemistry. 2008;14(16):4816-22.PMID: 18425743 [PubMed - indexed for MEDLINE]Related articlesFree article

Salmonella typhimurium as a novel RNA interference vector for cancer gene therapy.

Basu D, Herlyn M.

Cancer Biol Ther. 2008 Jan;7(1):151-2. Epub 2008 Feb 11. No abstract available. PMID: 18347415 [PubMed - indexed for MEDLINE]Related articles

Learning the ABCs of melanoma-initiating cells.

Zabierowski SE, Herlyn M.

Cancer Cell. 2008 Mar;13(3):185-7.PMID: 18328422 [PubMed - indexed for MEDLINE]Related articles

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity.

Tsai J, Lee JT, Wang W, Zhang J, Cho H, Mamo S, Bremer R, Gillette S, Kong J, Haass NK, Sproesser K, Li L, Smalley KS, Fong D, Zhu YL, Marimuthu A, Nguyen H, Lam B, Liu J, Cheung I, Rice J, Suzuki Y, Luu C, Settachatgul C, Shellooe R, Cantwell J, Kim SH, Schlessinger J, Zhang KY, West BL, Powell B, Habets G, Zhang C, Ibrahim PN, Hirth P, Artis DR, Herlyn M, Bollag G.

Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3041-6. Epub 2008 Feb 19.PMID: 18287029 [PubMed - indexed for MEDLINE]Related articlesFree article

The differential role of L1 in ovarian carcinoma and normal ovarian surface epithelium.

Zecchini S, Bianchi M, Colombo N, Fasani R, Goisis G, Casadio C, Viale G, Liu J, Herlyn M, Godwin AK, Nuciforo PG, Cavallaro U.

Cancer Res. 2008 Feb 15;68(4):1110-8.PMID: 18281486 [PubMed - indexed for MEDLINE]Related articlesFree article

Modeling genomic diversity and tumor dependency in malignant melanoma.

Lin WM, Baker AC, Beroukhim R, Winckler W, Feng W, Marmion JM, Laine E, Greulich H, Tseng H, Gates C, Hodi FS, Dranoff G, Sellers WR, Thomas RK, Meyerson M, Golub TR, Dummer R, Herlyn M, Getz G, Garraway LA.

Cancer Res. 2008 Feb 1;68(3):664-73.PMID: 18245465 [PubMed - indexed for MEDLINE]Related articlesFree article

Cancer testis antigens in human melanoma stem cells: expression, distribution, and methylation status.

Sigalotti L, Covre A, Zabierowski S, Himes B, Colizzi F, Natali PG, Herlyn M, Maio M.

J Cell Physiol. 2008 May;215(2):287-91.PMID: 18205182 [PubMed - indexed for MEDLINE]Related articles

Microscale solution IEF combined with 2-D DIGE substantially enhances analysis depth of complex proteomes such as mammalian cell and tissue extracts.

Han MJ, Herlyn M, Fisher AB, Speicher DW.

Electrophoresis. 2008 Feb;29(3):695-705.PMID: 18186533 [PubMed - indexed for MEDLINE]Related articles

The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel.

Haass NK, Sproesser K, Nguyen TK, Contractor R, Medina CA, Nathanson KL, Herlyn M, Smalley KS.

Clin Cancer Res. 2008 Jan 1;14(1):230-9.PMID: 18172275 [PubMed - indexed for MEDLINE]Related articlesFree article

Permissive environment in postnatal wounds induced by adenoviral-mediated overexpression of the anti-inflammatory cytokine interleukin-10 prevents scar formation.

Gordon A, Kozin ED, Keswani SG, Vaikunth SS, Katz AB, Zoltick PW, Favata M, Radu AP, Soslowsky LJ, Herlyn M, Crombleholme TM.

Wound Repair Regen. 2008 Jan-Feb;16(1):70-9. Epub 2007 Dec 13.PMID: 18086289 [PubMed - indexed for MEDLINE]Related articles

Roadmap for new opportunities in melanoma research.

Herlyn M, Halaban R, Ronai Z, Schuchter L, Berwick M, Pinkel D.

Semin Oncol. 2007 Dec;34(6):566-76.PMID: 18083380 [PubMed - indexed for MEDLINE]Related articles

The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation.

Okawa T, Michaylira CZ, Kalabis J, Stairs DB, Nakagawa H, Andl CD, Johnstone CN, Klein-Szanto AJ, El-Deiry WS, Cukierman E, Herlyn M, Rustgi AK.

Genes Dev. 2007 Nov 1;21(21):2788-803.PMID: 17974918 [PubMed - indexed for MEDLINE]Related articlesFree article

Downregulation of CCN3 expression as a potential mechanism for melanoma progression.

Fukunaga-Kalabis M, Martinez G, Telson SM, Liu ZJ, Balint K, Juhasz I, Elder DE, Perbal B, Herlyn M.

Oncogene. 2008 Apr 17;27(18):2552-60. Epub 2007 Oct 29.PMID: 17968313 [PubMed - indexed for MEDLINE]Related articles

The many faces of Notch signaling in skin-derived cells.

Pinnix CC, Herlyn M.

Pigment Cell Res. 2007 Dec;20(6):458-65. Review.PMID: 17935489 [PubMed - indexed for MEDLINE]Related articles

Unraveling mysteries of the multifunctional protein SPARC.

Fukunaga-Kalabis M, Herlyn M.

J Invest Dermatol. 2007 Nov;127(11):2497-8.PMID: 17934501 [PubMed - indexed for MEDLINE]Related articlesFree article

Raf inhibitor stabilizes receptor for the type I interferon but inhibits its anti-proliferative effects in human malignant melanoma cells.

Kumar KG, Liu J, Li Y, Yu D, Thomas-Tikhonenko A, Herlyn M, Fuchs SY.

Cancer Biol Ther. 2007 Sep;6(9):1437-41. Epub 2007 Jun 13.PMID: 17873516 [PubMed - indexed for MEDLINE]Related articlesFree article

Old disease, new culprit: tumor stem cells in cancer.

Lee JT, Herlyn M.

J Cell Physiol. 2007 Dec;213(3):603-9. Review.PMID: 17786956 [PubMed - indexed for MEDLINE]Related articles

Association of polymorphisms of FAS-1377, FAS-670, and FASL-844 genes with risk factors for cutaneous malignant melanoma.

Gaddipati H, Herlyn M.

Cancer J. 2007 Jul-Aug;13(4):226-8. No abstract available. PMID: 17762755 [PubMed - indexed for MEDLINE]Related articles

Expression of integrin alpha10 is induced in malignant melanoma.

Wenke AK, Kjellman C, Lundgren-Akerlund E, Uhlmann C, Haass NK, Herlyn M, Bosserhoff AK.

Cell Oncol. 2007;29(5):373-86.PMID: 17726260 [PubMed - indexed for MEDLINE]Related articles

Application of a BRAF pyrosequencing assay for mutation detection and copy number analysis in malignant melanoma.

Spittle C, Ward MR, Nathanson KL, Gimotty PA, Rappaport E, Brose MS, Medina A, Letrero R, Herlyn M, Edwards RH.

J Mol Diagn. 2007 Sep;9(4):464-71. Epub 2007 Aug 9.PMID: 17690212 [PubMed - indexed for MEDLINE]Related articlesFree article

Rewired ERK-JNK signaling pathways in melanoma.

Lopez-Bergami P, Huang C, Goydos JS, Yip D, Bar-Eli M, Herlyn M, Smalley KS, Mahale A, Eroshkin A, Aaronson S, Ronai Z.

Cancer Cell. 2007 May;11(5):447-60.PMID: 17482134 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutant V600E BRAF increases hypoxia inducible factor-1alpha expression in melanoma.

Kumar SM, Yu H, Edwards R, Chen L, Kazianis S, Brafford P, Acs G, Herlyn M, Xu X.

Cancer Res. 2007 Apr 1;67(7):3177-84.PMID: 17409425 [PubMed - indexed for MEDLINE]Related articlesFree article

Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment.

Meier F, Busch S, Lasithiotakis K, Kulms D, Garbe C, Maczey E, Herlyn M, Schittek B.

Br J Dermatol. 2007 Jun;156(6):1204-13. Epub 2007 Mar 28.PMID: 17388918 [PubMed - indexed for MEDLINE]Related articles