PubMed

Effects of AVE2268, a substituted glycopyranoside, on urinary glucose excretion and blood glucose in mice and rats.

Bickel M, Brummerhop H, Frick W, Glombik H, Herling AW, Heuer HO, Plettenburg O, Theis S, Werner U, Kramer W.

Arzneimittelforschung. 2008;58(11):574-80.PMID: 19137908 [PubMed - indexed for MEDLINE]Related articles

Adenosine A1 receptors regulate lipolysis and lipogenesis in mouse adipose tissue-interactions with insulin.

Johansson SM, Lindgren E, Yang JN, Herling AW, Fredholm BB.

Eur J Pharmacol. 2008 Nov 12;597(1-3):92-101. Epub 2008 Aug 31.PMID: 18789919 [PubMed - indexed for MEDLINE]Related articles

Reversal of visceral adiposity in candy-diet fed female Wistar rats by the CB1 receptor antagonist rimonabant.

Herling AW, Kilp S, Juretschke HP, Neumann-Haefelin C, Gerl M, Kramer W.

Int J Obes (Lond). 2008 Sep;32(9):1363-72. Epub 2008 Jul 15.PMID: 18626484 [PubMed - indexed for MEDLINE]Related articles

Increased energy expenditure contributes more to the body weight-reducing effect of rimonabant than reduced food intake in candy-fed wistar rats.

Herling AW, Kilp S, Elvert R, Haschke G, Kramer W.

Endocrinology. 2008 May;149(5):2557-66. Epub 2008 Feb 14.PMID: 18276749 [PubMed - indexed for MEDLINE]Related articlesFree article

Dysregulated pyruvate dehydrogenase complex in Zucker diabetic fatty rats.

Schummer CM, Werner U, Tennagels N, Schmoll D, Haschke G, Juretschke HP, Patel MS, Gerl M, Kramer W, Herling AW.

Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E88-96. Epub 2007 Oct 23.PMID: 17957038 [PubMed - indexed for MEDLINE]Related articlesFree article

CB1 receptor antagonist AVE1625 affects primarily metabolic parameters independently of reduced food intake in Wistar rats.

Herling AW, Gossel M, Haschke G, Stengelin S, Kuhlmann J, Müller G, Schmoll D, Kramer W.

Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E826-32. Epub 2007 Jun 26.PMID: 17595216 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of glucose 6-phosphate in mediating the effects of glucokinase overexpression on hepatic glucose metabolism.

Härndahl L, Schmoll D, Herling AW, Agius L.

FEBS J. 2006 Jan;273(2):336-46.PMID: 16403021 [PubMed - indexed for MEDLINE]Related articles

Muscle type-specific fatty acid metabolism in insulin resistance: an integrated in vivo study in Zucker diabetic fatty rats.

Beha A, Juretschke HP, Kuhlmann J, Neumann-Haefelin C, Belz U, Gerl M, Kramer W, Roden M, Herling AW.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E989-97. Epub 2005 Dec 27.PMID: 16380389 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression profiling in skeletal muscle of Zucker diabetic fatty rats: implications for a role of stearoyl-CoA desaturase 1 in insulin resistance.

Voss MD, Beha A, Tennagels N, Tschank G, Herling AW, Quint M, Gerl M, Metz-Weidmann C, Haun G, Korn M.

Diabetologia. 2005 Dec;48(12):2622-30. Epub 2005 Nov 12.PMID: 16284748 [PubMed - indexed for MEDLINE]Related articles

Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes.

Klabunde T, Wendt KU, Kadereit D, Brachvogel V, Burger HJ, Herling AW, Oikonomakos NG, Kosmopoulou MN, Schmoll D, Sarubbi E, von Roedern E, Schönafinger K, Defossa E.

J Med Chem. 2005 Oct 6;48(20):6178-93.PMID: 16190745 [PubMed - indexed for MEDLINE]Related articles

Correlation between insulin resistance and intramyocellular lipid levels in rats.

Kuhlmann J, Neumann-Haefelin C, Belz U, Kramer W, Juretschke HP, Herling AW.

Magn Reson Med. 2005 Jun;53(6):1275-82.PMID: 15906287 [PubMed - indexed for MEDLINE]Related articles

Characterization of adenosine-A1 receptor-mediated antilipolysis in rats by tissue microdialysis, 1H-spectroscopy, and glucose clamp studies.

Schoelch C, Kuhlmann J, Gossel M, Mueller G, Neumann-Haefelin C, Belz U, Kalisch J, Biemer-Daub G, Kramer W, Juretschke HP, Herling AW.

Diabetes. 2004 Jul;53(7):1920-6.PMID: 15220221 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle-type specific intramyocellular and hepatic lipid metabolism during starvation in wistar rats.

Neumann-Haefelin C, Beha A, Kuhlmann J, Belz U, Gerl M, Quint M, Biemer-Daub G, Broenstrup M, Stein M, Kleinschmidt E, Schaefer HL, Schmoll D, Kramer W, Juretschke HP, Herling AW.

Diabetes. 2004 Mar;53(3):528-34.PMID: 14988234 [PubMed - indexed for MEDLINE]Related articlesFree article

Determinants of intramyocellular lipid concentrations in rat hindleg muscle.

Neumann-Haefelin C, Kuhlmann J, Belz U, Kalisch J, Quint M, Gerl M, Juretschke HP, Herling AW.

Magn Reson Med. 2003 Aug;50(2):242-8.PMID: 12876699 [PubMed - indexed for MEDLINE]Related articles

Intramyocellular lipid and insulin resistance: a longitudinal in vivo 1H-spectroscopic study in Zucker diabetic fatty rats.

Kuhlmann J, Neumann-Haefelin C, Belz U, Kalisch J, Juretschke HP, Stein M, Kleinschmidt E, Kramer W, Herling AW.

Diabetes. 2003 Jan;52(1):138-44.PMID: 12502504 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of autophagic proteolysis by inhibitors of phosphoinositide 3-kinase can interfere with the regulation of glycogen synthesis in isolated hepatocytes.

Dubbelhuis PF, Van Sluijters DA, Blommaart EF, Gustafson LA, Van Woerkom GM, Herling AW, Burger HJ, Meijer AJ.

Biochem J. 2002 Dec 15;368(Pt 3):827-33.PMID: 12371905 [PubMed - indexed for MEDLINE]Related articlesFree article

Prolonged blood glucose reduction in mrp-2 deficient rats (GY/TR(-)) by the glucose-6-phosphate translocase inhibitor S 3025.

Herling AW, Schwab D, Burger HJ, Maas J, Hammerl R, Schmidt D, Strohschein S, Hemmerle H, Schubert G, Petry S, Kramer W.

Biochim Biophys Acta. 2002 Jan 15;1569(1-3):105-10.PMID: 11853963 [PubMed - indexed for MEDLINE]Related articles

Acute inhibition of glucose-6-phosphate translocator activity leads to increased de novo lipogenesis and development of hepatic steatosis without affecting VLDL production in rats.

Bandsma RH, Wiegman CH, Herling AW, Burger HJ, ter Harmsel A, Meijer AJ, Romijn JA, Reijngoud DJ, Kuipers F.

Diabetes. 2001 Nov;50(11):2591-7.PMID: 11679439 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid and amino acid modulation of glucose cycling in isolated rat hepatocytes.

Gustafson LA, Neeft M, Reijngoud DJ, Kuipers F, Sauerwein HP, Romijn JA, Herling AW, Burger HJ, Meijer AJ.

Biochem J. 2001 Sep 15;358(Pt 3):665-71.PMID: 11535127 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute inhibition of hepatic glucose-6-phosphatase does not affect gluconeogenesis but directs gluconeogenic flux toward glycogen in fasted rats. A pharmacological study with the chlorogenic acid derivative S4048.

van Dijk TH, van der Sluijs FH, Wiegman CH, Baller JF, Gustafson LA, Burger HJ, Herling AW, Kuipers F, Meijer AJ, Reijngoud DJ.

J Biol Chem. 2001 Jul 13;276(28):25727-35. Epub 2001 May 9.PMID: 11346646 [PubMed - indexed for MEDLINE]Related articlesFree article

The cardiac K+ channel KCNQ1 is essential for gastric acid secretion.

Grahammer F, Herling AW, Lang HJ, Schmitt-Gräff A, Wittekindt OH, Nitschke R, Bleich M, Barhanin J, Warth R.

Gastroenterology. 2001 May;120(6):1363-71.PMID: 11313306 [PubMed - indexed for MEDLINE]Related articles

Hepatic uptake of synthetic chlorogenic acid derivatives by the organic anion transport proteins.

Schwab D, Herling AW, Hemmerle H, Schubert G, Hagenbuch B, Burger HJ.

J Pharmacol Exp Ther. 2001 Jan;296(1):91-8.PMID: 11123367 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacological interference with hepatic glucose production.

Burger HJ, Schubert G, Hemmerle H, Kramer W, Herling AW.

Ann N Y Acad Sci. 1999 Nov 18;892:312-4. No abstract available. PMID: 10842672 [PubMed - indexed for MEDLINE]Related articles

Leptin effect in ob/ob mice under thermoneutral conditions depends not necessarily on central satiation.

Rafael J, Herling AW.

Am J Physiol Regul Integr Comp Physiol. 2000 Mar;278(3):R790-5.PMID: 10712302 [PubMed - indexed for MEDLINE]Related articles

Upregulation of hepatic glucose 6-phosphatase gene expression in rats treated with an inhibitor of glucose-6-phosphate translocase.

Simon C, Herling AW, Preibisch G, Burger HJ.

Arch Biochem Biophys. 2000 Jan 15;373(2):418-28.PMID: 10620367 [PubMed - indexed for MEDLINE]Related articles

Alterations of carbohydrate and lipid intermediary metabolism during inhibition of glucose-6-phosphatase in rats.

Herling AW, Burger H, Schubert G, Hemmerle H, Schaefer H, Kramer W.

Eur J Pharmacol. 1999 Dec 10;386(1):75-82.PMID: 10611466 [PubMed - indexed for MEDLINE]Related articles

Pharmacodynamic profile of a novel inhibitor of the hepatic glucose-6-phosphatase system.

Herling AW, Burger HJ, Schwab D, Hemmerle H, Below P, Schubert G.

Am J Physiol. 1998 Jun;274(6 Pt 1):G1087-93.PMID: 9696709 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of 3-mercaptopicolinic acid and a derivative of chlorogenic acid (S-3483) on hepatic and islet glucose-6-phosphatase activity.

Khan A, Ling ZC, Pukk K, Herling AW, Landau BR, Efendic S.

Eur J Pharmacol. 1998 May 22;349(2-3):325-31.PMID: 9671114 [PubMed - indexed for MEDLINE]Related articles

Chlorogenic acid analogue S 3483: a potent competitive inhibitor of the hepatic and renal glucose-6-phosphatase systems.

Arion WJ, Canfield WK, Ramos FC, Su ML, Burger HJ, Hemmerle H, Schubert G, Below P, Herling AW.

Arch Biochem Biophys. 1998 Mar 15;351(2):279-85.PMID: 9514661 [PubMed - indexed for MEDLINE]Related articles

Direct evidence for the involvement of two glucose 6-phosphate-binding sites in the glucose-6-phosphatase activity of intact liver microsomes. Characterization of T1, the microsomal glucose 6-phosphate transport protein by a direct binding assay.

Arion WJ, Canfield WK, Callaway ES, Burger HJ, Hemmerle H, Schubert G, Herling AW, Oekonomopulos R.

J Biol Chem. 1998 Mar 13;273(11):6223-7.PMID: 9497346 [PubMed - indexed for MEDLINE]Related articlesFree article

Chlorogenic acid and hydroxynitrobenzaldehyde: new inhibitors of hepatic glucose 6-phosphatase.

Arion WJ, Canfield WK, Ramos FC, Schindler PW, Burger HJ, Hemmerle H, Schubert G, Below P, Herling AW.

Arch Biochem Biophys. 1997 Mar 15;339(2):315-22.PMID: 9056264 [PubMed - indexed for MEDLINE]Related articles

Chlorogenic acid and synthetic chlorogenic acid derivatives: novel inhibitors of hepatic glucose-6-phosphate translocase.

Hemmerle H, Burger HJ, Below P, Schubert G, Rippel R, Schindler PW, Paulus E, Herling AW.

J Med Chem. 1997 Jan 17;40(2):137-45.PMID: 9003513 [PubMed - indexed for MEDLINE]Related articles

Gastric H+/K(+)-ATPase inhibitors.

Herling AW, Weidmann K.

Prog Med Chem. 1994;31:233-64. Review. No abstract available. PMID: 8029475 [PubMed - indexed for MEDLINE]Related articles

[Divided animal protection: study of a natural science and human science evaluation of the federal German animal welfare law]

Herling AW.

Dtsch Tierarztl Wochenschr. 1993 Sep;100(9):359-61. German. PMID: 8223237 [PubMed - indexed for MEDLINE]Related articles

[Hunting and animal protection]

Herling AW.

Dtsch Tierarztl Wochenschr. 1993 Apr;100(4):156-9. Review. German. PMID: 8486093 [PubMed - indexed for MEDLINE]Related articles

2-[(2-pyridylmethyl)sulfinyl]-1H-thieno[3,4-d]imidazoles. A novel class of gastric H+/K(+)-ATPase inhibitors.

Weidmann K, Herling AW, Lang HJ, Scheunemann KH, Rippel R, Nimmesgern H, Scholl T, Bickel M, Metzger H.

J Med Chem. 1992 Feb 7;35(3):438-50.PMID: 1310742 [PubMed - indexed for MEDLINE]Related articles

Gastric acid inhibitory profile of saviprazole (HOE 731) compared to omeprazole.

Herling AW, Scholl T, Bickel M, Lang HJ, Scheunemann KH, Weidmann K, Rippel R.

Pharmacology. 1991;43(6):293-303.PMID: 1664524 [PubMed - indexed for MEDLINE]Related articles

The inhibitory effect of HOE 731 in isolated rabbit gastric glands.

Herling AW, Becht M, Lang HJ, Scheunemann KH, Weidmann K, Scholl T, Rippel R.

Biochem Pharmacol. 1990 Oct 15;40(8):1809-14.PMID: 2173590 [PubMed - indexed for MEDLINE]Related articles

Effects of the novel anti-ulcer agent 1-(5'-oxohexyl)-3-methyl-7-propyl xanthine on experimental ulcers and gastric secretion in rats.

Tanaka T, Bickel M, Herling AW, Sakurai M, Goto M, Hayashi S.

Arzneimittelforschung. 1989 Jun;39(6):689-94.PMID: 2775336 [PubMed - indexed for MEDLINE]Related articles

Effects of verapamil on gastric acid secretion in vitro and in vivo.

Herling AW, Ljungström M.

Eur J Pharmacol. 1988 Nov 8;156(3):341-50.PMID: 2850932 [PubMed - indexed for MEDLINE]Related articles

Chemical and biologic characteristics of roxatidine acetate.

Bickel M, Herling AW, Schoelkens B, Scholtholt J.

Scand J Gastroenterol Suppl. 1988;146:78-88.PMID: 2906471 [PubMed - indexed for MEDLINE]Related articles

A review of the animal pharmacology of roxatidine acetate.

Scholtholt J, Bickel M, Herling AW.

Drugs. 1988;35 Suppl 3:30-40. Review.PMID: 2905247 [PubMed - indexed for MEDLINE]Related articles

A substituted thieno[3.4-d]imidazole versus substituted benzimidazoles as H+, K+-ATPase inhibitors.

Herling AW, Bickel M, Lang HJ, Weidmann K, Rösner M, Metzger H, Rippel R, Nimmesgern H, Scheunemann KH.

Pharmacology. 1988;36(5):289-97.PMID: 2841691 [PubMed - indexed for MEDLINE]Related articles

Inhibition of 14C-aminopyrine accumulation in isolated rabbit gastric glands by the H2-receptor antagonist HOE 760 (TZU-0460).

Herling AW, Becht M, Kelker W, Ljungström M, Bickel M.

Agents Actions. 1987 Feb;20(1-2):35-9.PMID: 2883849 [PubMed - indexed for MEDLINE]Related articles

Improved enrichment of functionally intact anterior pituitary cells by sequential centrifugal elutriation and density gradient sedimentation.

Scheikl-Lenz B, Sandow J, Herling AW, Träger L, Kuhl H.

Acta Endocrinol (Copenh). 1986 Oct;113(2):211-8.PMID: 3535325 [PubMed - indexed for MEDLINE]Related articles

Antisecretory effects of two new histamine H2-receptor antagonists.

Bickel M, Herling AW, Rising TJ, Wirth K.

Arzneimittelforschung. 1986 Sep;36(9):1358-63.PMID: 2878669 [PubMed - indexed for MEDLINE]Related articles

The stimulatory effect of forskolin on gastric acid secretion in rats.

Herling AW, Bickel M.

Eur J Pharmacol. 1986 Jun 17;125(2):233-9.PMID: 2427345 [PubMed - indexed for MEDLINE]Related articles