PubMed

Effects of plasma membrane Ca(2+)-ATPase overexpression upon D-glucose metabolism in insulin-producing BRIN-BD11 cells.

Kamagate A, Sener A, Courtois P, Malaisse WJ, Herchuelz A.

Biosci Rep. 2008 Oct;28(5):251-8.PMID: 18643776 [PubMed - indexed for MEDLINE]Related articles

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.

Cunha DA, Hekerman P, Ladrière L, Bazarra-Castro A, Ortis F, Wakeham MC, Moore F, Rasschaert J, Cardozo AK, Bellomo E, Overbergh L, Mathieu C, Lupi R, Hai T, Herchuelz A, Marchetti P, Rutter GA, Eizirik DL, Cnop M.

J Cell Sci. 2008 Jul 15;121(Pt 14):2308-18. Epub 2008 Jun 17.PMID: 18559892 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage.

Molinaro P, Cuomo O, Pignataro G, Boscia F, Sirabella R, Pannaccione A, Secondo A, Scorziello A, Adornetto A, Gala R, Viggiano D, Sokolow S, Herchuelz A, Schurmans S, Di Renzo G, Annunziato L.

J Neurosci. 2008 Jan 30;28(5):1179-84.PMID: 18234895 [PubMed - indexed for MEDLINE]Related articlesFree article

NCX3 knockout mice exhibit increased hippocampal CA1 and CA2 neuronal damage compared to wild-type mice following global cerebral ischemia.

Jeffs GJ, Meloni BP, Sokolow S, Herchuelz A, Schurmans S, Knuckey NW.

Exp Neurol. 2008 Mar;210(1):268-73. Epub 2007 Nov 1.PMID: 18054916 [PubMed - indexed for MEDLINE]Related articles

Carbamylcholine and ouabain effects on Ca2+ handling and insulin release in islets from rats depleted in long-chain polyunsaturated omega 3 fatty acids.

Louchami K, Zhang Y, Carpentier YA, Chardigny JM, Malaisse WJ, Herchuelz A, Sener A.

Endocrine. 2007 Oct;32(2):148-54. Epub 2007 Nov 27.PMID: 18040892 [PubMed - indexed for MEDLINE]Related articles

Overexpression of Na/Ca exchanger reduces viability and proliferation of gliosarcoma cells.

Nguidjoe E, Herchuelz A.

Ann N Y Acad Sci. 2007 Mar;1099:468. No abstract available. PMID: 17446487 [PubMed - indexed for MEDLINE]Related articles

Role of Na/Ca exchange and the plasma membrane Ca2+-ATPase in beta cell function and death.

Herchuelz A, Kamagate A, Ximenes H, Van Eylen F.

Ann N Y Acad Sci. 2007 Mar;1099:456-67. Review.PMID: 17446486 [PubMed - indexed for MEDLINE]Related articles

Historical note regarding the discovery of the Na/Ca exchanger and the PMCA.

Herchuelz A.

Ann N Y Acad Sci. 2007 Mar;1099:xvii-xviii. No abstract available. PMID: 17446444 [PubMed - indexed for MEDLINE]Related articles

Role of Na/Ca exchange and the plasma membrane Ca2+-ATPase in cell function. Conference on Na/Ca exchange.

Noble D, Herchuelz A.

EMBO Rep. 2007 Mar;8(3):228-32. Epub 2007 Feb 9. No abstract available. PMID: 17290287 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic islet function in omega-3 fatty acid-depleted rats: alteration of calcium fluxes and calcium-dependent insulin release.

Zhang Y, Oguzhan B, Louchami K, Chardigny JM, Portois L, Carpentier YA, Malaisse WJ, Herchuelz A, Sener A.

Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E441-8.PMID: 16912059 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells.

Cardozo AK, Ortis F, Storling J, Feng YM, Rasschaert J, Tonnesen M, Van Eylen F, Mandrup-Poulsen T, Herchuelz A, Eizirik DL.

Diabetes. 2005 Feb;54(2):452-61.PMID: 15677503 [PubMed - indexed for MEDLINE]Related articlesFree article

Na/Ca exchanger overexpression induces endoplasmic reticulum stress, caspase-12 release, and apoptosis.

Díaz-Horta O, Van Eylen F, Herchuelz A.

Ann N Y Acad Sci. 2003 Dec;1010:430-2.PMID: 15033764 [PubMed - indexed for MEDLINE]Related articles

Impaired neuromuscular transmission and skeletal muscle fiber necrosis in mice lacking Na/Ca exchanger 3.

Sokolow S, Manto M, Gailly P, Molgó J, Vandebrouck C, Vanderwinden JM, Herchuelz A, Schurmans S.

J Clin Invest. 2004 Jan;113(2):265-73.PMID: 14722618 [PubMed - indexed for MEDLINE]Related articlesFree article

Opposite effects of glucose on plasma membrane Ca2+-ATPase and Na/Ca exchanger transcription, expression, and activity in rat pancreatic beta-cells.

Ximenes HM, Kamagate A, Van Eylen F, Carpinelli A, Herchuelz A.

J Biol Chem. 2003 Jun 20;278(25):22956-63. Epub 2003 Apr 7.PMID: 12682074 [PubMed - indexed for MEDLINE]Related articlesFree article

Na/Ca exchange and Ca2+ homeostasis in the pancreatic beta-cell.

Herchuelz A, Diaz-Horta O, van Eylen F.

Diabetes Metab. 2002 Dec;28(6 Pt 2):3S54-60; discussion 3S108-12. Review.PMID: 12688634 [PubMed - indexed for MEDLINE]Related articles

Effect of glucose on the expression level of the plasma membrane Ca2+-ATPase and the Na+/Ca2+ exchanger in pancreatic islet cells.

Ximenes HM, Kamagate A, Van Eylen F, Herchuelz A.

Ann N Y Acad Sci. 2002 Nov;976:354-5. No abstract available. PMID: 12502581 [PubMed - indexed for MEDLINE]Related articles

Na/Ca exchange in function, growth, and demise of beta-cells.

Herchuelz A, Diaz-Horta O, Van Eylen F.

Ann N Y Acad Sci. 2002 Nov;976:315-24. Review.PMID: 12502574 [PubMed - indexed for MEDLINE]Related articles

Conformational changes of the 120-kDa Na+/Ca2+ exchanger protein upon ligand binding: a Fourier transform infrared spectroscopy study.

Saba RI, Goormaghtigh E, Ruysschaert JM, Herchuelz A.

Ann N Y Acad Sci. 2002 Nov;976:97-9. No abstract available. PMID: 12502544 [PubMed - indexed for MEDLINE]Related articles

Characterization and functional activity of a truncated Na/Ca exchange isoform resulting from a new splicing pattern of NCX1.

Van Eylen F, Kamagate A, Herchuelz A.

Ann N Y Acad Sci. 2002 Nov;976:81-4. No abstract available. PMID: 12502539 [PubMed - indexed for MEDLINE]Related articles

Plasma membrane Ca(2+)-ATPase overexpression reduces Ca(2+) oscillations and increases insulin release induced by glucose in insulin-secreting BRIN-BD11 cells.

Kamagate A, Herchuelz A, Van Eylen F.

Diabetes. 2002 Sep;51(9):2773-88.PMID: 12196471 [PubMed - indexed for MEDLINE]Related articlesFree article

Na/Ca exchanger overexpression induces endoplasmic reticulum-related apoptosis and caspase-12 activation in insulin-releasing BRIN-BD11 cells.

Diaz-Horta O, Kamagate A, Herchuelz A, Van Eylen F.

Diabetes. 2002 Jun;51(6):1815-24.PMID: 12031969 [PubMed - indexed for MEDLINE]Related articlesFree article

The SleepStrip: an apnoea screener for the early detection of sleep apnoea syndrome.

Shochat T, Hadas N, Kerkhofs M, Herchuelz A, Penzel T, Peter JH, Lavie P.

Eur Respir J. 2002 Jan;19(1):121-6.PMID: 11843310 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of the Na/Ca exchanger shapes stimulus-induced cytosolic Ca(2+) oscillations in insulin-producing BRIN-BD11 cells.

Van Eylen F, Horta OD, Barez A, Kamagate A, Flatt PR, Macianskiene R, Mubagwa K, Herchuelz A.

Diabetes. 2002 Feb;51(2):366-75.PMID: 11812743 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel inhibitors of the sodium-calcium exchanger: benzene ring analogues of N-guanidino substituted amiloride derivatives.

Rogister F, Laeckmann D, Plasman P, Van Eylen F, Ghyoot M, Maggetto C, Liégeois J, Géczy J, Herchuelz A, Delarge J, Masereel B.

Eur J Med Chem. 2001 Jul-Aug;36(7-8):597-614.PMID: 11600230 [PubMed - indexed for MEDLINE]Related articles

A new Na/Ca exchanger splicing pattern identified in situ leads to a functionally active 70kDa NH(2)-terminal protein.

Van Eylen F, Kamagate A, Herchuelz A.

Cell Calcium. 2001 Sep;30(3):191-8.PMID: 11508998 [PubMed - indexed for MEDLINE]Related articles

Conformational changes of the 120-kDa Na+/Ca2+ exchanger protein upon ligand binding: a Fourier transform infrared spectroscopy study.

Saba RI, Goormaghtigh E, Ruysschaert JM, Herchuelz A.

Biochemistry. 2001 Mar 20;40(11):3324-32.PMID: 11258952 [PubMed - indexed for MEDLINE]Related articles

NCX1 Na/Ca exchanger splice variants in pancreatic islet cells.

Van Eylen F, Bollen A, Herchuelz A.

J Endocrinol. 2001 Mar;168(3):517-26.PMID: 11241183 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of multiple plasma membrane Ca(2+)-ATPases in rat pancreatic islet cells.

Kamagate A, Herchuelz A, Bollen A, Van Eylen F.

Cell Calcium. 2000 Apr;27(4):231-46.PMID: 10858669 [PubMed - indexed for MEDLINE]Related articles

Fourier transform infrared spectroscopy study of the secondary and tertiary structure of the reconstituted Na+/Ca2+ exchanger 70-kDa polypeptide.

Saba RI, Ruysschaert JM, Herchuelz A, Goormaghtigh E.

J Biol Chem. 1999 May 28;274(22):15510-8.PMID: 10336444 [PubMed - indexed for MEDLINE]Related articlesFree article

Significance of Na/Ca exchange for Ca2+ buffering and electrical activity in mouse pancreatic beta-cells.

Gall D, Gromada J, Susa I, Rorsman P, Herchuelz A, Bokvist K.

Biophys J. 1999 Apr;76(4):2018-28.PMID: 10096898 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the 70 kDa polypeptide of the Na/Ca exchanger.

Saba RI, Bollen A, Herchuelz A.

Biochem J. 1999 Feb 15;338 ( Pt 1):139-45.PMID: 9931309 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulinotropic action of beta-L-glucose pentaacetate.

Malaisse WJ, Best LC, Herchuelz A, Hiriart M, Jijakli H, Kadiata MM, Larrieta-Carasco E, Laghmich A, Louchami K, Mercan D, Olivares E, Sánchez-Soto C, Scruel O, Sener A, Valverde I, Villanueva-Peñacarrillo ML, Viñambres C, Zawalich WS.

Am J Physiol. 1998 Dec;275(6 Pt 1):E993-E1006.PMID: 9843742 [PubMed - indexed for MEDLINE]Related articlesFree article

Contribution of Na/Ca exchange to Ca2+ outflow and entry in the rat pancreatic beta-cell: studies with antisense oligonucleotides.

Van Eylen F, Lebeau C, Albuquerque-Silva J, Herchuelz A.

Diabetes. 1998 Dec;47(12):1873-80.PMID: 9836518 [PubMed - indexed for MEDLINE]Related articlesFree article

Verapamil, a phenylalkylamine Ca2+ channel blocker, inhibits ATP-sensitive K+ channels in insulin-secreting cells from rats.

Lebrun P, Antoine MH, Ouedraogo R, Pirotte B, Herchuelz A, Cosgrove KE, Kane C, Dunne MJ.

Diabetologia. 1997 Dec;40(12):1403-10.PMID: 9447947 [PubMed - indexed for MEDLINE]Related articles

3-Morpholinosydnonimine as instigator of a glibenclamide-sensitive reduction in the insulin secretory rate.

Antoine MH, Ouedraogo R, Hermann M, Segooris J, Herchuelz A, Lebrun P.

Biochem Pharmacol. 1997 Apr 25;53(8):1211-3. Erratum in: Biochem Pharmacol 1997 Jun 15;53(12):1946. PMID: 9175727 [PubMed - indexed for MEDLINE]Related articles

Identification, expression pattern and potential activity of Na/Ca exchanger isoforms in rat pancreatic B-cells.

Van Eylen F, Svoboda M, Herchuelz A.

Cell Calcium. 1997 Mar;21(3):185-93.PMID: 9105728 [PubMed - indexed for MEDLINE]Related articles

Cell culture conditions influence glucose-induced [Ca2+]i responses in isolated rat pancreatic B cells.

Antoine MH, Lebrun P, Herchuelz A.

Adv Exp Med Biol. 1997;426:227-30. No abstract available. PMID: 9544279 [PubMed - indexed for MEDLINE]Related articles

Phe-Met-Arg-Phe-NH2 (FMRFa)-related peptides inhibit Na/Ca exchange in pancreatic B cells.

Van Eylen F, Gourlet P, Vandermeers A, Lebrun P, Herchuelz A.

Adv Exp Med Biol. 1997;426:223-5. No abstract available. PMID: 9544278 [PubMed - indexed for MEDLINE]Related articles

Pyridothiadiazines as potent inhibitors of glucose-induced insulin release.

Lebrun P, Antoine MH, Ouedraogo R, Herchuelz A, de Tullio P, Delarge J, Pirotte B.

Adv Exp Med Biol. 1997;426:145-8. No abstract available. PMID: 9544267 [PubMed - indexed for MEDLINE]Related articles

Hydroxylamine, a nitric oxide donor, inhibits insulin release and activates K+ATP channels.

Antoine MH, Ouedraogo R, Sergooris J, Hermann M, Herchuelz A, Lebrun P.

Eur J Pharmacol. 1996 Oct 17;313(3):229-35.PMID: 8911919 [PubMed - indexed for MEDLINE]Related articles

Effects of Phe-Met-Arg-Phe-NH2 (FMRFa)-related peptides on Na-Ca exchange and ionic fluxes in rat pancreatic B cells.

Van Eylen F, Gourlet P, Vandermeers A, Lebrun P, Herchuelz A.

Ann N Y Acad Sci. 1996 Apr 15;779:288-9. No abstract available. PMID: 8659839 [PubMed - indexed for MEDLINE]Related articles

Presence of NACA3 and NACA7 exchanger isoforms in insulin-producing cells.

Van Eylen F, Svoboda M, Bollen A, Herchuelz A.

Ann N Y Acad Sci. 1996 Apr 15;779:132-3. No abstract available. PMID: 8659822 [PubMed - indexed for MEDLINE]Related articles

Bioequivalence assessment and the conduct of bioequivalence trials: a European point of view.

Herchuelz A.

Eur J Drug Metab Pharmacokinet. 1996 Apr-Jun;21(2):149-52. No abstract available. PMID: 8839688 [PubMed - indexed for MEDLINE]Related articles

Activation of ATP-dependent K+ channels and inhibition of insulin release: effect of BPDZ 62.

Lebrun P, Antoine MH, Ouedraogo R, Kane C, Dunne M, Hermann M, Herchuelz A, Masereel B, Delarge J, de Tullio P, Pirotte B.

J Pharmacol Exp Ther. 1996 Apr;277(1):156-62.PMID: 8613913 [PubMed - indexed for MEDLINE]Related articles

[Na/Ca exchange]

Herchuelz A.

Bull Mem Acad R Med Belg. 1996;151(1):125-31; discussion 131-4. French. PMID: 8963256 [PubMed - indexed for MEDLINE]Related articles

Thyroid function parameters during a selenium repletion/depletion study in phenylketonuric subjects.

Calomme MR, Vanderpas JB, François B, Van Caillie-Bertrand M, Herchuelz A, Vanovervelt N, Van Hoorebeke C, Vanden Berghe DA.

Experientia. 1995 Dec 18;51(12):1208-15.PMID: 8536808 [PubMed - indexed for MEDLINE]Related articles

Pituitary adenylate cyclase activating polypeptide (PACAP) and vasoactive intestinal peptide stimulate two signaling pathways in CHO cells stably transfected with the selective type I PACAP receptor.

Delporte C, Poloczek P, de Neef P, Vertongen P, Ciccarelli E, Svoboda M, Herchuelz A, Winand J, Robberecht P.

Mol Cell Endocrinol. 1995 Jan;107(1):71-6.PMID: 7796937 [PubMed - indexed for MEDLINE]Related articles

Inhibition of Na/Ca exchange by Phe-Met-Arg-Phe-NH2 (FMRFa)-related peptides in intact rat pancreatic B-cells.

Van Eylen F, Gourlet P, Vandermeers A, Lebrun P, Herchuelz A.

Mol Cell Endocrinol. 1994 Dec;106(1-2):R1-5.PMID: 7534729 [PubMed - indexed for MEDLINE]Related articles

Cationic and secretory effects of BPDZ 44 and diazoxide in rat pancreatic islets.

Antoine MH, Pirotte B, Hermann M, de Tullio P, Delarge J, Herchuelz A, Lebrun P.

Experientia. 1994 Sep 15;50(9):830-2.PMID: 7925849 [PubMed - indexed for MEDLINE]Related articles

A pyridothiadiazine (BPDZ 44) as a new and potent activator of ATP-sensitive K+ channels.

Pirotte B, Antoine MH, de Tullio P, Hermann M, Herchuelz A, Delarge J, Lebrun P.

Biochem Pharmacol. 1994 Apr 20;47(8):1381-6.PMID: 8185645 [PubMed - indexed for MEDLINE]Related articles