PubMed

Leptin receptor 170 KDa (OB-R170) protein expression is reduced in obese human skeletal muscle: a potential mechanism of leptin resistance.

Fuentes T, Ara I, Guadalupe-Grau A, Larsen S, Stallknecht B, Olmedillas H, Santana A, Helge JW, Calbet JA, Guerra B.

Exp Physiol. 2009 Aug 28. [Epub ahead of print]PMID: 19717488 [PubMed - as supplied by publisher]Related articles

Hypoadiponectinemia in overweight children contributes to a negative metabolic risk profile 6 years later.

Kynde I, Heitmann BL, Bygbjerg IC, Andersen LB, Helge JW.

Metabolism. 2009 Dec;58(12):1817-24. Epub 2009 Aug 27.PMID: 19716142 [PubMed - in process]Related articles

Childhood hypo-adiponectinaemia but not hyper-leptinaemia is associated with insulin insensitivity 6 years later.

Kynde I, Heitmann BL, Bygbjerg IC, Andersen LB, Helge JW.

Pediatr Diabetes. 2009 Aug 4. [Epub ahead of print]PMID: 19671091 [PubMed - as supplied by publisher]Related articles

Impact of the growth hormone receptor exon 3 deletion gene polymorphism on glucose metabolism, lipids, and insulin-like growth factor-I levels during puberty.

Sørensen K, Aksglaede L, Munch-Andersen T, Aachmann-Andersen NJ, Leffers H, Helge JW, Hilsted L, Juul A.

J Clin Endocrinol Metab. 2009 Aug;94(8):2966-9. Epub 2009 May 5.PMID: 19417039 [PubMed - indexed for MEDLINE]Related articles

Are substrate use during exercise and mitochondrial respiratory capacity decreased in arm and leg muscle in type 2 diabetes?

Larsen S, Ara I, Rabøl R, Andersen JL, Boushel R, Dela F, Helge JW.

Diabetologia. 2009 Jul;52(7):1400-8. Epub 2009 Apr 25.PMID: 19396425 [PubMed - indexed for MEDLINE]Related articles

Dual regulation of muscle glycogen synthase during exercise by activation and compartmentalization.

Prats C, Helge JW, Nordby P, Qvortrup K, Ploug T, Dela F, Wojtaszewski JF.

J Biol Chem. 2009 Jun 5;284(23):15692-700. Epub 2009 Apr 1.PMID: 19339242 [PubMed - indexed for MEDLINE]Related articles

Sex hormone-binding globulin levels predict insulin sensitivity, disposition index, and cardiovascular risk during puberty.

Sørensen K, Aksglaede L, Munch-Andersen T, Aachmann-Andersen NJ, Petersen JH, Hilsted L, Helge JW, Juul A.

Diabetes Care. 2009 May;32(5):909-14. Epub 2009 Feb 5.PMID: 19196890 [PubMed - indexed for MEDLINE]Related articlesFree article

Human skeletal muscle ceramide content is not a major factor in muscle insulin sensitivity.

Skovbro M, Baranowski M, Skov-Jensen C, Flint A, Dela F, Gorski J, Helge JW.

Diabetologia. 2008 Jul;51(7):1253-60. Epub 2008 May 6.PMID: 18458871 [PubMed - indexed for MEDLINE]Related articles

Effect of gender on lipid-induced insulin resistance in obese subjects.

Vistisen B, Hellgren LI, Vadset T, Scheede-Bergdahl C, Helge JW, Dela F, Stallknecht B.

Eur J Endocrinol. 2008 Jan;158(1):61-8.PMID: 18166818 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of physical training on endothelial function and limb blood flow in type 2 diabetes.

Sonne MP, Scheede-Bergdahl C, Olsen DB, Højbjerre L, Alibegovic A, Nielsen NB, Stallknecht B, Helge JW, Vaag A, Dela F.

Appl Physiol Nutr Metab. 2007 Oct;32(5):936-41. Review.PMID: 18059619 [PubMed - indexed for MEDLINE]Related articles

Interleukin-18 in plasma and adipose tissue: effects of obesity, insulin resistance, and weight loss.

Bruun JM, Stallknecht B, Helge JW, Richelsen B.

Eur J Endocrinol. 2007 Oct;157(4):465-71.PMID: 17893261 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac output and leg and arm blood flow during incremental exercise to exhaustion on the cycle ergometer.

Calbet JA, Gonzalez-Alonso J, Helge JW, Søndergaard H, Munch-Andersen T, Boushel R, Saltin B.

J Appl Physiol. 2007 Sep;103(3):969-78. Epub 2007 Jun 28.PMID: 17600155 [PubMed - indexed for MEDLINE]Related articlesFree article

Four weeks one-leg training and high fat diet does not alter PPARalpha protein or mRNA expression in human skeletal muscle.

Helge JW, Bentley D, Schjerling P, Willer M, Gibala MJ, Franch J, Tapia-Laliena MA, Daugaard JR, Andersen JL.

Eur J Appl Physiol. 2007 Sep;101(1):105-14. Epub 2007 May 26.PMID: 17530276 [PubMed - indexed for MEDLINE]Related articles

Increased fat oxidation and regulation of metabolic genes with ultraendurance exercise.

Helge JW, Rehrer NJ, Pilegaard H, Manning P, Lucas SJ, Gerrard DF, Cotter JD.

Acta Physiol (Oxf). 2007 Sep;191(1):77-86. Epub 2007 May 3.PMID: 17488246 [PubMed - indexed for MEDLINE]Related articles

Muscle metabolism during graded quadriceps exercise in man.

Helge JW, Stallknecht B, Richter EA, Galbo H, Kiens B.

J Physiol. 2007 Jun 15;581(Pt 3):1247-58. Epub 2007 Mar 22.PMID: 17379639 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-intensity training dissociates metabolic from aerobic fitness.

Helge JW, Damsgaard R, Overgaard K, Andersen JL, Donsmark M, Dyrskog SE, Hermansen K, Saltin B, Daugaard JR.

Scand J Med Sci Sports. 2008 Feb;18(1):86-94. Epub 2007 Mar 12.PMID: 17355324 [PubMed - indexed for MEDLINE]Related articles

Contraction-mediated glucose uptake is increased in men with impaired glucose tolerance.

Skov-Jensen C, Skovbro M, Flint A, Helge JW, Dela F.

Appl Physiol Nutr Metab. 2007 Feb;32(1):115-24.PMID: 17332788 [PubMed - indexed for MEDLINE]Related articles

[Eating for top performance in sports?]

Helge JW, Dela F.

Ugeskr Laeger. 2006 Dec 18;168(51):4510. Danish. No abstract available. PMID: 17228408 [PubMed - indexed for MEDLINE]Related articles

Maximal fat oxidation rates in endurance trained and untrained women.

Stisen AB, Stougaard O, Langfort J, Helge JW, Sahlin K, Madsen K.

Eur J Appl Physiol. 2006 Nov;98(5):497-506. Epub 2006 Sep 28.PMID: 17006714 [PubMed - indexed for MEDLINE]Related articles

Are blood flow and lipolysis in subcutaneous adipose tissue influenced by contractions in adjacent muscles in humans?

Stallknecht B, Dela F, Helge JW.

Am J Physiol Endocrinol Metab. 2007 Feb;292(2):E394-9. Epub 2006 Sep 19.PMID: 16985258 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle triacylglycerol and hormone-sensitive lipase activity in untrained and trained human muscles.

Helge JW, Biba TO, Galbo H, Gaster M, Donsmark M.

Eur J Appl Physiol. 2006 Jul;97(5):566-72. Epub 2006 Jun 10.PMID: 16767439 [PubMed - indexed for MEDLINE]Related articles

Whole-body fat oxidation determined by graded exercise and indirect calorimetry: a role for muscle oxidative capacity?

Nordby P, Saltin B, Helge JW.

Scand J Med Sci Sports. 2006 Jun;16(3):209-14.PMID: 16643200 [PubMed - indexed for MEDLINE]Related articles

Do energy density and dietary fiber influence subsequent 5-year weight changes in adult men and women?

Iqbal SI, Helge JW, Heitmann BL.

Obesity (Silver Spring). 2006 Jan;14(1):106-14.PMID: 16493128 [PubMed - indexed for MEDLINE]Related articles

Repeated prolonged whole-body low-intensity exercise: effects on insulin sensitivity and limb muscle adaptations.

Helge JW, Overgaard K, Damsgaard R, Sørensen K, Andersen JL, Dyrskog SE, Hermansen K, Saltin B, Wojtaszewski JF.

Metabolism. 2006 Feb;55(2):217-23.PMID: 16423629 [PubMed - indexed for MEDLINE]Related articles

[Lifestyle intervention in the treatment of severe obesity]

Pedersen JØ, Zimmermann E, Stallknecht BM, Bruun JM, Kroustrup JP, Larsen JF, Helge JW.

Ugeskr Laeger. 2006 Jan 9;168(2):167-72. Danish. PMID: 16403343 [PubMed - indexed for MEDLINE]Related articles

Diet and exercise reduce low-grade inflammation and macrophage infiltration in adipose tissue but not in skeletal muscle in severely obese subjects.

Bruun JM, Helge JW, Richelsen B, Stallknecht B.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E961-7. Epub 2005 Dec 13.PMID: 16352667 [PubMed - indexed for MEDLINE]Related articlesFree article

Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise.

Pilegaard H, Osada T, Andersen LT, Helge JW, Saltin B, Neufer PD.

Metabolism. 2005 Aug;54(8):1048-55.PMID: 16092055 [PubMed - indexed for MEDLINE]Related articles

Studies of plasma membrane fatty acid-binding protein and other lipid-binding proteins in human skeletal muscle.

Roepstorff C, Helge JW, Vistisen B, Kiens B.

Proc Nutr Soc. 2004 May;63(2):239-44. Review.PMID: 15294037 [PubMed - indexed for MEDLINE]Related articles

Muscle dysfunction during exercise of a single skeletal muscle in rats with congestive heart failure is not associated with reduced muscle blood supply.

Schiøtz Thorud HM, Lunde PK, Nicolaysen G, Nicolaysen A, Helge JW, Nilsson GE, Sejersted OM.

Acta Physiol Scand. 2004 Jun;181(2):173-81.PMID: 15180789 [PubMed - indexed for MEDLINE]Related articles

Exercise and training effects on ceramide metabolism in human skeletal muscle.

Helge JW, Dobrzyn A, Saltin B, Gorski J.

Exp Physiol. 2004 Jan;89(1):119-27.PMID: 15109217 [PubMed - indexed for MEDLINE]Related articlesFree article

Interstitial glycerol concentrations in human skeletal muscle and adipose tissue during graded exercise.

Stallknecht B, Kiens B, Helge JW, Richter EA, Galbo H.

Acta Physiol Scand. 2004 Apr;180(4):367-77.PMID: 15030378 [PubMed - indexed for MEDLINE]Related articles

Effect of training on muscle triacylglycerol and structural lipids: a relation to insulin sensitivity?

Helge JW, Dela F.

Diabetes. 2003 Aug;52(8):1881-7.PMID: 12882901 [PubMed - indexed for MEDLINE]Related articlesFree article

Skiing across the Greenland icecap: divergent effects on limb muscle adaptations and substrate oxidation.

Helge JW, Lundby C, Christensen DL, Langfort J, Messonnier L, Zacho M, Andersen JL, Saltin B.

J Exp Biol. 2003 Mar;206(Pt 6):1075-83.PMID: 12582149 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of graded exercise on IL-6 release and glucose uptake in human skeletal muscle.

Helge JW, Stallknecht B, Pedersen BK, Galbo H, Kiens B, Richter EA.

J Physiol. 2003 Jan 1;546(Pt 1):299-305.PMID: 12509497 [PubMed - indexed for MEDLINE]Related articlesFree article

Partial restoration of dietary fat induced metabolic adaptations to training by 7 days of carbohydrate diet.

Helge JW, Watt PW, Richter EA, Rennie MJ, Kiens B.

J Appl Physiol. 2002 Nov;93(5):1797-805.PMID: 12381768 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term fat diet adaptation effects on performance, training capacity, and fat utilization.

Helge JW.

Med Sci Sports Exerc. 2002 Sep;34(9):1499-504. Review.PMID: 12218745 [PubMed - indexed for MEDLINE]Related articles

Prolonged adaptation to fat-rich diet and training; effects on body fat stores and insulin resistance in man.

Helge JW.

Int J Obes Relat Metab Disord. 2002 Aug;26(8):1118-24.PMID: 12119578 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of pre-exercise muscle glycogen content on exercise-induced transcriptional regulation of metabolic genes.

Pilegaard H, Keller C, Steensberg A, Helge JW, Pedersen BK, Saltin B, Neufer PD.

J Physiol. 2002 May 15;541(Pt 1):261-71.PMID: 12015434 [PubMed - indexed for MEDLINE]Related articlesFree article

Fat utilization during exercise: adaptation to a fat-rich diet increases utilization of plasma fatty acids and very low density lipoprotein-triacylglycerol in humans.

Helge JW, Watt PW, Richter EA, Rennie MJ, Kiens B.

J Physiol. 2001 Dec 15;537(Pt 3):1009-20.PMID: 11744773 [PubMed - indexed for MEDLINE]Related articlesFree article

Eccentric contractions affect muscle membrane phospholipid fatty acid composition in rats.

Helge JW, Therkildsen KJ, Jørgensen TB, Wu BJ, Storlien LH, Asp S.

Exp Physiol. 2001 Sep;86(5):599-604.PMID: 11571487 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance. Influence of diet and physical activity.

Storlien LH, Tapsell LC, Fraser A, Leslie E, Ball K, Higgins JA, Helge JW, Owen N.

World Rev Nutr Diet. 2001;90:26-43. Review. No abstract available. PMID: 11545043 [PubMed - indexed for MEDLINE]Related articles

Training affects muscle phospholipid fatty acid composition in humans.

Helge JW, Wu BJ, Willer M, Daugaard JR, Storlien LH, Kiens B.

J Appl Physiol. 2001 Feb;90(2):670-7.PMID: 11160068 [PubMed - indexed for MEDLINE]Related articlesFree article

[Skeletal muscles, physical activity and health]

Saltin B, Helge JW.

Orthopade. 2000 Nov;29(11):941-7. Review. German. PMID: 11149279 [PubMed - indexed for MEDLINE]Related articles

Caffeine ingestion does not alter carbohydrate or fat metabolism in human skeletal muscle during exercise.

Graham TE, Helge JW, MacLean DA, Kiens B, Richter EA.

J Physiol. 2000 Dec 15;529 Pt 3:837-47.PMID: 11118510 [PubMed - indexed for MEDLINE]Related articlesFree article

Adaptation to a fat-rich diet: effects on endurance performance in humans.

Helge JW.

Sports Med. 2000 Nov;30(5):347-57. Review.PMID: 11103848 [PubMed - indexed for MEDLINE]Related articles

Training and natural immunity: effects of diets rich in fat or carbohydrate.

Pedersen BK, Helge JW, Richter EA, Rohde T, Kiens B.

Eur J Appl Physiol. 2000 May;82(1-2):98-102.PMID: 10879449 [PubMed - indexed for MEDLINE]Related articles

[Metabolic capacity of skeletal muscles and health]

Saltin B, Helge JW.

Ugeskr Laeger. 2000 Apr 10;162(15):2159-64. Review. Danish. PMID: 10776058 [PubMed - indexed for MEDLINE]Related articles

Interrelationships between muscle fibre type, substrate oxidation and body fat.

Helge JW, Fraser AM, Kriketos AD, Jenkins AB, Calvert GD, Ayre KJ, Storlien LH.

Int J Obes Relat Metab Disord. 1999 Sep;23(9):986-91.PMID: 10490806 [PubMed - indexed for MEDLINE]Related articles

Regular exercise modulates muscle membrane phospholipid profile in rats.

Helge JW, Ayre KJ, Hulbert AJ, Kiens B, Storlien LH.

J Nutr. 1999 Sep;129(9):1636-42.PMID: 10460197 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin sensitivity, muscle fibre types, and membrane lipids.

Helge JW, Kriketos AD, Storlien LH.

Adv Exp Med Biol. 1998;441:129-38. Review.PMID: 9781320 [PubMed - indexed for MEDLINE]Related articles