PubMed

Nephron-deficient Fvb mice develop rapidly progressive renal failure and heavy albuminuria involving excess glomerular GLUT1 and VEGF.

Wang Y, Heilig KO, Minto AW, Chen S, Xiang M, Dean DA, Geiger RC, Chang A, Pravtcheva DD, Schlimme M, Deb DK, Wang Y, Heilig CW.

Lab Invest. 2009 Nov 16. [Epub ahead of print]PMID: 19918242 [PubMed - as supplied by publisher]Related articles

GLUT1-induced cFLIP expression promotes proliferation and prevents apoptosis in vascular smooth muscle cells.

Vesely ED, Heilig CW, Brosius FC 3rd.

Am J Physiol Cell Physiol. 2009 Sep;297(3):C759-65. Epub 2009 Jul 8.PMID: 19587217 [PubMed - indexed for MEDLINE]Related articles

Increased glucose uptake and metabolism in mesangial cells overexpressing glucose transporter 1 increases interleukin-6 and vascular endothelial growth factor production: role of AP-1 and HIF-1alpha.

Pfäfflin A, Brodbeck K, Heilig CW, Häring HU, Schleicher ED, Weigert C.

Cell Physiol Biochem. 2006;18(4-5):199-210.PMID: 17167225 [PubMed - indexed for MEDLINE]Related articles

Altered vitamin D metabolism in type II diabetic mouse glomeruli may provide protection from diabetic nephropathy.

Wang Y, Zhou J, Minto AW, Hack BK, Alexander JJ, Haas M, Li YC, Heilig CW, Quigg RJ.

Kidney Int. 2006 Sep;70(5):882-91. Epub 2006 Jul 5.PMID: 16820793 [PubMed - indexed for MEDLINE]Related articles

Role for GLUT1 in diabetic glomerulosclerosis.

Heilig CW, Brosius FC 3rd, Cunningham C.

Expert Rev Mol Med. 2006 Feb 6;8(4):1-18. Review.PMID: 16515729 [PubMed - indexed for MEDLINE]Related articles

Diabetic nephropathy: of mice and men.

Breyer MD, Böttinger E, Brosius FC, Coffman TM, Fogo A, Harris RC, Heilig CW, Sharma K.

Adv Chronic Kidney Dis. 2005 Apr;12(2):128-45. Review.PMID: 15822049 [PubMed - indexed for MEDLINE]Related articles

Glucose transporters in diabetic nephropathy.

Brosius FC, Heilig CW.

Pediatr Nephrol. 2005 Apr;20(4):447-51. Epub 2005 Feb 17. Review.PMID: 15717166 [PubMed - indexed for MEDLINE]Related articles

Mouse models of diabetic nephropathy.

Breyer MD, Böttinger E, Brosius FC 3rd, Coffman TM, Harris RC, Heilig CW, Sharma K; AMDCC.

J Am Soc Nephrol. 2005 Jan;16(1):27-45. Epub 2004 Nov 24. Review.PMID: 15563560 [PubMed - indexed for MEDLINE]Related articlesFree article

GLUT1-deficient mice exhibit impaired endothelium-dependent vascular relaxation.

Park JL, Heilig CW, Brosius FC 3rd.

Eur J Pharmacol. 2004 Aug 2;496(1-3):213-4.PMID: 15288593 [PubMed - indexed for MEDLINE]Related articles

Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy.

Heilig CW, Saunders T, Brosius FC 3rd, Moley K, Heilig K, Baggs R, Guo L, Conner D.

Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15613-8. Epub 2003 Dec 12.PMID: 14673082 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of cytosolic pH and lactic acid release in mesangial cells overexpressing GLUT1.

Lang KS, Mueller MM, Tanneur V, Wallisch S, Fedorenko O, Palmada M, Lang F, Bröer S, Heilig CW, Schleicher E, Weigert C.

Kidney Int. 2003 Oct;64(4):1338-47.PMID: 12969152 [PubMed - indexed for MEDLINE]Related articles

Evidence for a novel TGF-beta1-independent mechanism of fibronectin production in mesangial cells overexpressing glucose transporters.

Weigert C, Brodbeck K, Brosius FC 3rd, Huber M, Lehmann R, Friess U, Facchin S, Aulwurm S, Häring HU, Schleicher ED, Heilig CW.

Diabetes. 2003 Feb;52(2):527-35.PMID: 12540631 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a novel form of renal glucosuria with overexcretion of arginine, carnosine, and taurine.

Sankarasubbaiyan S, Cooper C, Heilig CW.

Am J Kidney Dis. 2001 May;37(5):1039-43.PMID: 11325687 [PubMed - indexed for MEDLINE]Related articles

Antisense GLUT-1 protects mesangial cells from glucose induction of GLUT-1 and fibronectin expression.

Heilig CW, Kreisberg JI, Freytag S, Murakami T, Ebina Y, Guo L, Heilig K, Loberg R, Qu X, Jin Y, Henry D, Brosius FC 3rd.

Am J Physiol Renal Physiol. 2001 Apr;280(4):F657-66.PMID: 11249857 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-specific regulation of aldose reductase in human retinal pigment epithelial cells in vitro.

Henry DN, Frank RN, Hootman SR, Rood SE, Heilig CW, Busik JV.

Invest Ophthalmol Vis Sci. 2000 May;41(6):1554-60.PMID: 10798676 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose transporters control gene expression of aldose reductase, PKCalpha, and GLUT1 in mesangial cells in vitro.

Henry DN, Busik JV, Brosius FC 3rd, Heilig CW.

Am J Physiol. 1999 Jul;277(1 Pt 2):F97-104.PMID: 10409302 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose transporters of the glomerulus and the implications for diabetic nephropathy.

Heilig CW, Brosius FC 3rd, Henry DN.

Kidney Int Suppl. 1997 Sep;60:S91-9. Review.PMID: 9285909 [PubMed - indexed for MEDLINE]Related articles

D-glucose stimulates mesangial cell GLUT1 expression and basal and IGF-I-sensitive glucose uptake in rat mesangial cells: implications for diabetic nephropathy.

Heilig CW, Liu Y, England RL, Freytag SO, Gilbert JD, Heilig KO, Zhu M, Concepcion LA, Brosius FC 3rd.

Diabetes. 1997 Jun;46(6):1030-9.PMID: 9166676 [PubMed - indexed for MEDLINE]Related articles

Overexpression of glucose transporters in rat mesangial cells cultured in a normal glucose milieu mimics the diabetic phenotype.

Heilig CW, Concepcion LA, Riser BL, Freytag SO, Zhu M, Cortes P.

J Clin Invest. 1995 Oct;96(4):1802-14.PMID: 7560072 [PubMed - indexed for MEDLINE]Related articlesFree article

Common fluid-electrolyte and acid-base problems in the intensive care unit: selected issues.

Faber MD, Kupin WL, Heilig CW, Narins RG.

Semin Nephrol. 1994 Jan;14(1):8-22. Review. No abstract available. PMID: 8140344 [PubMed - indexed for MEDLINE]Related articles

Upregulation of inositol transport mediates inositol accumulation in hyperosmolar brain cells.

Strange K, Morrison R, Heilig CW, DiPietro S, Gullans SR.

Am J Physiol. 1991 Apr;260(4 Pt 1):C784-90.PMID: 2018110 [PubMed - indexed for MEDLINE]Related articles

Modulation of osmolytes in MDCK cells by solutes, inhibitors, and vasopressin.

Heilig CW, Brenner RM, Yu AS, Kone BC, Gullans SR.

Am J Physiol. 1990 Oct;259(4 Pt 2):F653-9.PMID: 2221103 [PubMed - indexed for MEDLINE]Related articles

Methylamine and polyol responses to salt loading in renal inner medulla.

Heilig CW, Stromski ME, Gullans SR.

Am J Physiol. 1989 Dec;257(6 Pt 2):F1117-23.PMID: 2603958 [PubMed - indexed for MEDLINE]Related articles

Characterization of the major brain osmolytes that accumulate in salt-loaded rats.

Heilig CW, Stromski ME, Blumenfeld JD, Lee JP, Gullans SR.

Am J Physiol. 1989 Dec;257(6 Pt 2):F1108-16.PMID: 2603957 [PubMed - indexed for MEDLINE]Related articles

Organic osmolytes in inner medulla of Brattleboro rat: effects of ADH and dehydration.

Blumenfeld JD, Hebert SC, Heilig CW, Balschi JA, Stromski ME, Gullans SR.

Am J Physiol. 1989 May;256(5 Pt 2):F916-22.PMID: 2719121 [PubMed - indexed for MEDLINE]Related articles

Methylamines and polyols in kidney, urinary bladder, urine, liver, brain, and plasma. An analysis using 1H nuclear magnetic resonance spectroscopy.

Gullans SR, Heilig CW, Stromski ME, Blumenfeld JD.

Ren Physiol Biochem. 1989 May-Jun;12(3):191-201.PMID: 2623345 [PubMed - indexed for MEDLINE]Related articles

Accumulation of major organic osmolytes in rat renal inner medulla in dehydration.

Gullans SR, Blumenfeld JD, Balschi JA, Kaleta M, Brenner RM, Heilig CW, Hebert SC.

Am J Physiol. 1988 Oct;255(4 Pt 2):F626-34.PMID: 3177652 [PubMed - indexed for MEDLINE]Related articles

Dementia without Alzheimer pathology.

Heilig CW, Knopman DS, Mastri AR, Frey W 2nd.

Neurology. 1985 May;35(5):762-5.PMID: 2986048 [PubMed - indexed for MEDLINE]Related articles