PubMed

ATP-Binding Cassette Transporter G1 Negatively Regulates Thymocyte and Peripheral Lymphocyte Proliferation.

Armstrong AJ, Gebre AK, Parks JS, Hedrick CC.

J Immunol. 2009 Nov 30. [Epub ahead of print]PMID: 19949102 [PubMed - as supplied by publisher]

Murine 12/15-lipoxygenase regulates ATP-binding cassette transporter G1 protein degradation through p38- and JNK2-dependent pathways.

Nagelin MH, Srinivasan S, Nadler JL, Hedrick CC.

J Biol Chem. 2009 Nov 6;284(45):31303-14. Epub 2009 Aug 27.PMID: 19713213 [PubMed - in process]Related articles

G2A deficiency in mice promotes macrophage activation and atherosclerosis.

Bolick DT, Skaflen MD, Johnson LE, Kwon SC, Howatt D, Daugherty A, Ravichandran KS, Hedrick CC.

Circ Res. 2009 Feb 13;104(3):318-27. Epub 2008 Dec 23.PMID: 19106413 [PubMed - indexed for MEDLINE]Related articles

Sphingosine-1-phosphate inhibits high glucose-mediated ERK1/2 action in endothelium through induction of MAP kinase phosphatase-3.

Whetzel AM, Bolick DT, Hedrick CC.

Am J Physiol Cell Physiol. 2009 Feb;296(2):C339-45. Epub 2008 Dec 17.PMID: 19091959 [PubMed - indexed for MEDLINE]Related articles

The G protein-coupled receptor G2A: involvement in hepatic lipid metabolism and gallstone formation in mice.

Johnson LE, Elias MS, Bolick DT, Skaflen MD, Green RM, Hedrick CC.

Hepatology. 2008 Oct;48(4):1138-48.PMID: 18821587 [PubMed - indexed for MEDLINE]Related articles

Association of arachidonate 12-lipoxygenase genotype variation and glycemic control with albuminuria in type 2 diabetes.

Liu Y, Freedman BI, Burdon KP, Langefeld CD, Howard T, Herrington D, Goff DC Jr, Bowden DW, Wagenknecht LE, Hedrick CC, Rich SS.

Am J Kidney Dis. 2008 Aug;52(2):242-50. Epub 2008 Mar 25.PMID: 18640486 [PubMed - indexed for MEDLINE]Related articlesFree article

12/15-Lipoxygenase activity increases the degradation of macrophage ATP-binding cassette transporter G1.

Nagelin MH, Srinivasan S, Lee J, Nadler JL, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2008 Oct;28(10):1811-9. Epub 2008 Jul 17.PMID: 18635820 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced expression of ATP-binding cassette transporter G1 increases cholesterol accumulation in macrophages of patients with type 2 diabetes mellitus.

Mauldin JP, Nagelin MH, Wojcik AJ, Srinivasan S, Skaflen MD, Ayers CR, McNamara CA, Hedrick CC.

Circulation. 2008 May 27;117(21):2785-92. Epub 2008 May 19.PMID: 18490524 [PubMed - indexed for MEDLINE]Related articlesFree article

Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.

Hughes JE, Srinivasan S, Lynch KR, Proia RL, Ferdek P, Hedrick CC.

Circ Res. 2008 Apr 25;102(8):950-8. Epub 2008 Mar 6.PMID: 18323526 [PubMed - indexed for MEDLINE]Related articlesFree article

A critical role for ABCG1 in macrophage inflammation and lung homeostasis.

Wojcik AJ, Skaflen MD, Srinivasan S, Hedrick CC.

J Immunol. 2008 Mar 15;180(6):4273-82.PMID: 18322240 [PubMed - indexed for MEDLINE]Related articlesFree article

Sphingosine-1-phosphate reduces CD4+ T-cell activation in type 1 diabetes through regulation of hypoxia-inducible factor short isoform I.1 and CD69.

Srinivasan S, Bolick DT, Lukashev D, Lappas C, Sitkovsky M, Lynch KR, Hedrick CC.

Diabetes. 2008 Feb;57(2):484-93. Epub 2007 Nov 14.PMID: 18003758 [PubMed - indexed for MEDLINE]Related articlesFree article

Absence of the G protein-coupled receptor G2A in mice promotes monocyte/endothelial interactions in aorta.

Bolick DT, Whetzel AM, Skaflen M, Deem TL, Lee J, Hedrick CC.

Circ Res. 2007 Mar 2;100(4):572-80. Epub 2007 Jan 25.PMID: 17255525 [PubMed - indexed for MEDLINE]Related articlesFree article

Sphingosine-1 phosphate prevents monocyte/endothelial interactions in type 1 diabetic NOD mice through activation of the S1P1 receptor.

Whetzel AM, Bolick DT, Srinivasan S, Macdonald TL, Morris MA, Ley K, Hedrick CC.

Circ Res. 2006 Sep 29;99(7):731-9. Epub 2006 Sep 7.PMID: 16960101 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction in ABCG1 in Type 2 diabetic mice increases macrophage foam cell formation.

Mauldin JP, Srinivasan S, Mulya A, Gebre A, Parks JS, Daugherty A, Hedrick CC.

J Biol Chem. 2006 Jul 28;281(30):21216-24. Epub 2006 May 24.PMID: 16723355 [PubMed - indexed for MEDLINE]Related articlesFree article

12/15 lipoxygenase mediates monocyte adhesion to aortic endothelium in apolipoprotein E-deficient mice through activation of RhoA and NF-kappaB.

Bolick DT, Srinivasan S, Whetzel A, Fuller LC, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2006 Jun;26(6):1260-6. Epub 2006 Mar 16.PMID: 16543492 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific monocyte adhesion to endothelial cells induced by oxidized phospholipids involves activation of cPLA2 and lipoxygenase.

Huber J, Fürnkranz A, Bochkov VN, Patricia MK, Lee H, Hedrick CC, Berliner JA, Binder BR, Leitinger N.

J Lipid Res. 2006 May;47(5):1054-62. Epub 2006 Feb 5.PMID: 16461778 [PubMed - indexed for MEDLINE]Related articlesFree article

12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB.

Bolick DT, Orr AW, Whetzel A, Srinivasan S, Hatley ME, Schwartz MA, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2005 Nov;25(11):2301-7. Epub 2005 Sep 15.PMID: 16166569 [PubMed - indexed for MEDLINE]Related articlesFree article

The effects of leukocyte-type 12/15-lipoxygenase on Id3-mediated vascular smooth muscle cell growth.

Taylor AM, Hanchett R, Natarajan R, Hedrick CC, Forrest S, Nadler JL, McNamara CA.

Arterioscler Thromb Vasc Biol. 2005 Oct;25(10):2069-74. Epub 2005 Jul 21.PMID: 16037566 [PubMed - indexed for MEDLINE]Related articlesFree article

Sphingosine-1-phosphate prevents tumor necrosis factor-{alpha}-mediated monocyte adhesion to aortic endothelium in mice.

Bolick DT, Srinivasan S, Kim KW, Hatley ME, Clemens JJ, Whetzel A, Ferger N, Macdonald TL, Davis MD, Tsao PS, Lynch KR, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2005 May;25(5):976-81. Epub 2005 Mar 10.PMID: 15761190 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome scan for fasting insulin and fasting glucose identifies a quantitative trait locus on chromosome 17p: the insulin resistance atherosclerosis study (IRAS) family study.

Rich SS, Bowden DW, Haffner SM, Norris JM, Saad MF, Mitchell BD, Rotter JI, Langefeld CD, Hedrick CC, Wagenknecht LE, Bergman RN; Insulin Resistance Atherosclerosis Study (IRAS) Family Study.

Diabetes. 2005 Jan;54(1):290-5.PMID: 15616041 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperglycaemia-induced superoxide production decreases eNOS expression via AP-1 activation in aortic endothelial cells.

Srinivasan S, Hatley ME, Bolick DT, Palmer LA, Edelstein D, Brownlee M, Hedrick CC.

Diabetologia. 2004 Oct;47(10):1727-34. Epub 2004 Oct 13.PMID: 15490108 [PubMed - indexed for MEDLINE]Related articles

Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice.

Huo Y, Zhao L, Hyman MC, Shashkin P, Harry BL, Burcin T, Forlow SB, Stark MA, Smith DF, Clarke S, Srinivasan S, Hedrick CC, Praticò D, Witztum JL, Nadler JL, Funk CD, Ley K.

Circulation. 2004 Oct 5;110(14):2024-31. Epub 2004 Sep 27. Erratum in: Circulation. 2004 Nov 9;110(19):3156. PMID: 15451785 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose regulates interleukin-8 production in aortic endothelial cells through activation of the p38 mitogen-activated protein kinase pathway in diabetes.

Srinivasan S, Bolick DT, Hatley ME, Natarajan R, Reilly KB, Yeh M, Chrestensen C, Sturgill TW, Hedrick CC.

J Biol Chem. 2004 Jul 23;279(30):31930-6. Epub 2004 May 15.PMID: 15145956 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of macrophage-derived apolipoprotein E on hyperlipidemia and atherosclerosis of LDLR-deficient mice.

Shi W, Wang X, Wong J, Hedrick CC, Wong H, Castellani LW, Lusis AJ.

Biochem Biophys Res Commun. 2004 Apr 23;317(1):223-9.PMID: 15047172 [PubMed - indexed for MEDLINE]Related articles

Modulation of PPARalpha expression and inflammatory interleukin-6 production by chronic glucose increases monocyte/endothelial adhesion.

Srinivasan S, Hatley ME, Reilly KB, Danziger EC, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2004 May;24(5):851-7. Epub 2004 Mar 4.PMID: 15001458 [PubMed - indexed for MEDLINE]Related articlesFree article

12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo.

Reilly KB, Srinivasan S, Hatley ME, Patricia MK, Lannigan J, Bolick DT, Vandenhoff G, Pei H, Natarajan R, Nadler JL, Hedrick CC.

J Biol Chem. 2004 Mar 5;279(10):9440-50. Epub 2003 Dec 15.PMID: 14676201 [PubMed - indexed for MEDLINE]Related articlesFree article

Lisofylline, a novel antiinflammatory compound, protects mesangial cells from hyperglycemia- and angiotensin II-mediated extracellular matrix deposition.

Bolick DT, Hatley ME, Srinivasan S, Hedrick CC, Nadler JL.

Endocrinology. 2003 Dec;144(12):5227-31. Epub 2003 Aug 28.PMID: 12960000 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased production of 12/15 lipoxygenase eicosanoids accelerates monocyte/endothelial interactions in diabetic db/db mice.

Hatley ME, Srinivasan S, Reilly KB, Bolick DT, Hedrick CC.

J Biol Chem. 2003 Jul 11;278(28):25369-75. Epub 2003 May 6. Erratum in: J Biol Chem. 2003 Dec 12;278(50):50818. PMID: 12734208 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose regulates monocyte adhesion through endothelial production of interleukin-8.

Srinivasan S, Yeh M, Danziger EC, Hatley ME, Riggan AE, Leitinger N, Berliner JA, Hedrick CC.

Circ Res. 2003 Mar 7;92(4):371-7. Epub 2003 Feb 13.PMID: 12600878 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenoviral-mediated transfer of tissue plasminogen activator gene into brain capillary endothelial cells in vitro.

Kim JA, Hedrick CC, Xie D, Fisher MJ.

Angiology. 2001 Sep;52(9):627-34.PMID: 11570662 [PubMed - indexed for MEDLINE]Related articles

Adenoviral delivery of a leukocyte-type 12 lipoxygenase ribozyme inhibits effects of glucose and platelet-derived growth factor in vascular endothelial and smooth muscle cells.

Patricia MK, Natarajan R, Dooley AN, Hernandez F, Gu JL, Berliner JA, Rossi JJ, Nadler JL, Meidell RS, Hedrick CC.

Circ Res. 2001 Apr 13;88(7):659-65.PMID: 11304487 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo interactions of apoA-II, apoA-I, and hepatic lipase contributing to HDL structure and antiatherogenic functions.

Hedrick CC, Castellani LW, Wong H, Lusis AJ.

J Lipid Res. 2001 Apr;42(4):563-70.PMID: 11290828 [PubMed - indexed for MEDLINE]Related articlesFree article

Role for peroxisome proliferator-activated receptor alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells.

Lee H, Shi W, Tontonoz P, Wang S, Subbanagounder G, Hedrick CC, Hama S, Borromeo C, Evans RM, Berliner JA, Nagy L.

Circ Res. 2000 Sep 15;87(6):516-21.PMID: 10988245 [PubMed - indexed for MEDLINE]Related articlesFree article

Short-term feeding of atherogenic diet to mice results in reduction of HDL and paraoxonase that may be mediated by an immune mechanism.

Hedrick CC, Hassan K, Hough GP, Yoo JH, Simzar S, Quinto CR, Kim SM, Dooley A, Langi S, Hama SY, Navab M, Witztum JL, Fogelman AM.

Arterioscler Thromb Vasc Biol. 2000 Aug;20(8):1946-52.PMID: 10938016 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycation impairs high-density lipoprotein function.

Hedrick CC, Thorpe SR, Fu MX, Harper CM, Yoo J, Kim SM, Wong H, Peters AL.

Diabetologia. 2000 Mar;43(3):312-20.PMID: 10768092 [PubMed - indexed for MEDLINE]Related articles

12-Lipoxygenase products increase monocyte:endothelial interactions.

Hedrick CC, Kim MD, Natarajan RD, Nadler JL.

Adv Exp Med Biol. 1999;469:455-60.PMID: 10667368 [PubMed - indexed for MEDLINE]Related articles

Interleukin-10 blocks atherosclerotic events in vitro and in vivo.

Pinderski Oslund LJ, Hedrick CC, Olvera T, Hagenbaugh A, Territo M, Berliner JA, Fyfe AI.

Arterioscler Thromb Vasc Biol. 1999 Dec;19(12):2847-53.PMID: 10591660 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipoxygenase products increase monocyte adhesion to human aortic endothelial cells.

Patricia MK, Kim JA, Harper CM, Shih PT, Berliner JA, Natarajan R, Nadler JL, Hedrick CC.

Arterioscler Thromb Vasc Biol. 1999 Nov;19(11):2615-22.PMID: 10559003 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipoprotein and cholesterol metabolism in diet-induced coronary artery atherosclerosis in primates. Role of cholesterol and fatty acids.

Rudel LL, Parks JS, Hedrick CC, Thomas M, Williford K.

Prog Lipid Res. 1998 Dec;37(6):353-70. Review. No abstract available. PMID: 10209653 [PubMed - indexed for MEDLINE]Related articles

High density associated enzymes: their role in vascular biology.

Navab M, Hama SY, Hough GP, Hedrick CC, Sorenson R, La Du BN, Kobashigawa JA, Fonarow GC, Berliner JA, Laks H, Fogelman AM.

Curr Opin Lipidol. 1998 Oct;9(5):449-56. Review.PMID: 9812199 [PubMed - indexed for MEDLINE]Related articles

Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles.

Castellani LW, Navab M, Van Lenten BJ, Hedrick CC, Hama SY, Goto AM, Fogelman AM, Lusis AJ.

J Clin Invest. 1997 Jul 15;100(2):464-74.PMID: 9218525 [PubMed - indexed for MEDLINE]Related articlesFree article

Endogenous natural killer enhancing factor-B increases cellular resistance to oxidative stresses.

Shau H, Kim AT, Hedrick CC, Lusis AJ, Tompkins C, Finney R, Leung DW, Paglia DE.

Free Radic Biol Med. 1997;22(3):497-507.PMID: 8981042 [PubMed - indexed for MEDLINE]Related articles

Apolipoprotein A-II: a protein in search of a function.

Hedrick CC, Lusis AJ.

Can J Cardiol. 1994 May;10(4):453-9. Review.PMID: 8193990 [PubMed - indexed for MEDLINE]Related articles

Influence of mouse apolipoprotein A-II on plasma lipoproteins in transgenic mice.

Hedrick CC, Castellani LW, Warden CH, Puppione DL, Lusis AJ.

J Biol Chem. 1993 Sep 25;268(27):20676-82.PMID: 8376417 [PubMed - indexed for MEDLINE]Related articlesFree article

Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II.

Warden CH, Hedrick CC, Qiao JH, Castellani LW, Lusis AJ.

Science. 1993 Jul 23;261(5120):469-72. Erratum in: Science 1993 Oct 8;262(5131):164. PMID: 8332912 [PubMed - indexed for MEDLINE]Related articles

Superoxide generation by the human polymorphonuclear leukocyte in response to latex beads.

Thomas MJ, Hedrick CC, Smith S, Pang J, Jerome WG, Willard AS, Shirley PS.

J Leukoc Biol. 1992 Jun;51(6):591-6.PMID: 1319445 [PubMed - indexed for MEDLINE]Related articlesFree article

Latex beads as vehicles for the study of free radical processes in phagocytic cells.

Thomas MJ, Hedrick CC.

Basic Life Sci. 1988;49:853-6. No abstract available. PMID: 2855008 [PubMed - indexed for MEDLINE]Related articles

Role of free radical processes in stimulated human polymorphonuclear leukocytes.

Thomas MJ, Shirley PS, Hedrick CC, DeChatelet LR.

Biochemistry. 1986 Dec 2;25(24):8042-8.PMID: 3026467 [PubMed - indexed for MEDLINE]Related articles