PubMed

Immune Escape Mutations Detected Within HIV-1 Epitopes Associated With Viral Control During Treatment Interruption.

Schweighardt B, Wrin T, Meiklejohn DA, Spotts G, Petropoulos CJ, Nixon DF, Hecht FM.

J Acquir Immune Defic Syndr. 2009 Nov 12. [Epub ahead of print]PMID: 19910798 [PubMed - as supplied by publisher]Related articles

HIV-SELECTEST EIA AND RAPID TEST: ABILITY TO DETECT SEROCONVERSION FOLLOWING HIV-1 INFECTION.

Khurana S, Norris PJ, Busch MP, Haynes BF, Park S, Sasono P, Mlisana K, Salim AK, Hecht FM, Mulenga J, Chomba E, Hunter E, Allen S, Nemo G, Rodriguez-Chavez IR; Women's Interagency HIV Study; Joseph B. Margolick on behalf of Multicenter AIDS Cohort Study (MACS), Golding H.

J Clin Microbiol. 2009 Nov 11. [Epub ahead of print]PMID: 19906903 [PubMed - as supplied by publisher]Related articles

Characterization of human immunodeficiency virus type 1 populations containing CXCR4-using variants from recently infected individuals.

Huang W, Toma J, Stawiski E, Fransen S, Wrin T, Parkin N, Whitcomb JM, Coakley E, Hecht FM, Deeks SG, Gandhi RT, Eshleman SH, Petropoulos CJ.

AIDS Res Hum Retroviruses. 2009 Aug;25(8):795-802.PMID: 19678765 [PubMed - indexed for MEDLINE]Related articles

Lower cytokine secretion ex vivo by natural killer T cells in HIV-infected individuals is associated with higher CD161 expression.

Snyder-Cappione JE, Loo CP, Carvalho KI, Kuylenstierna C, Deeks SG, Hecht FM, Rosenberg MG, Sandberg JK, Kallas EG, Nixon DF.

AIDS. 2009 Sep 24;23(15):1965-70.PMID: 19590406 [PubMed - in process]Related articles

Transcriptional errors in human immunodeficiency virus type 1 generate targets for T-cell responses.

Garrison KE, Champiat S, York VA, Agrawal AT, Kallas EG, Martin JN, Hecht FM, Deeks SG, Nixon DF.

Clin Vaccine Immunol. 2009 Sep;16(9):1369-71. Epub 2009 Jul 1.PMID: 19571107 [PubMed - indexed for MEDLINE]Related articles

HIV-1-specific T Cell-dependent natural killer (NK) cell activation: major contribution by NK cells to interferon-gamma production in response to HIV-1 antigens.

Loo CP, Long BR, Hecht FM, Nixon DF, Michaëlsson J.

AIDS Res Hum Retroviruses. 2009 Jun;25(6):603-5.PMID: 19500013 [PubMed - indexed for MEDLINE]Related articles

Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells.

Streeck H, Jolin JS, Qi Y, Yassine-Diab B, Johnson RC, Kwon DS, Addo MM, Brumme C, Routy JP, Little S, Jessen HK, Kelleher AD, Hecht FM, Sekaly RP, Rosenberg ES, Walker BD, Carrington M, Altfeld M.

J Virol. 2009 Aug;83(15):7641-8. Epub 2009 May 20.PMID: 19458000 [PubMed - indexed for MEDLINE]Related articles

Body awareness: construct and self-report measures.

Mehling WE, Gopisetty V, Daubenmier J, Price CJ, Hecht FM, Stewart A.

PLoS One. 2009;4(5):e5614. Epub 2009 May 19. Review.PMID: 19440300 [PubMed - indexed for MEDLINE]Related articlesFree article

High CD8+ T cell activation marks a less differentiated HIV-1 specific CD8+ T cell response that is not altered by suppression of viral replication.

Barbour JD, Ndhlovu LC, Xuan Tan Q, Ho T, Epling L, Bredt BM, Levy JA, Hecht FM, Sinclair E.

PLoS One. 2009;4(2):e4408. Epub 2009 Feb 9.PMID: 19198651 [PubMed - indexed for MEDLINE]Related articlesFree article

Tolerability and efficacy of PI versus NNRTI-based regimens in subjects receiving HAART during acute or early HIV infection.

Apuzzo LG, Vaida F, Gallant JE, Ernstrom KB, Little SJ, Routy JP, Collier AC, Conway B, Markowitz MH, Hecht FM, Walker BD, Connick E, Margolick JB.

J Acquir Immune Defic Syndr. 2009 Mar 1;50(3):267-75.PMID: 19194317 [PubMed - indexed for MEDLINE]Related articles

Incomplete peripheral CD4+ cell count restoration in HIV-infected patients receiving long-term antiretroviral treatment.

Kelley CF, Kitchen CM, Hunt PW, Rodriguez B, Hecht FM, Kitahata M, Crane HM, Willig J, Mugavero M, Saag M, Martin JN, Deeks SG.

Clin Infect Dis. 2009 Mar 15;48(6):787-94.PMID: 19193107 [PubMed - indexed for MEDLINE]Related articlesFree article

CD8+ cell anti-HIV activity rapidly increases upon discontinuation of early antiretroviral therapy.

Killian MS, Roop J, Ng S, Hecht FM, Levy JA.

J Clin Immunol. 2009 May;29(3):311-8. Epub 2009 Feb 3.PMID: 19189205 [PubMed - indexed for MEDLINE]Related articles

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection.

Jones RB, Ndhlovu LC, Barbour JD, Sheth PM, Jha AR, Long BR, Wong JC, Satkunarajah M, Schweneker M, Chapman JM, Gyenes G, Vali B, Hyrcza MD, Yue FY, Kovacs C, Sassi A, Loutfy M, Halpenny R, Persad D, Spotts G, Hecht FM, Chun TW, McCune JM, Kaul R, Rini JM, Nixon DF, Ostrowski MA.

J Exp Med. 2008 Nov 24;205(12):2763-79. Epub 2008 Nov 10.PMID: 19001139 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunity to HIV-1 is influenced by continued natural exposure to exogenous virus.

Willberg CB, McConnell JJ, Eriksson EM, Bragg LA, York VA, Liegler TJ, Hecht FM, Grant RM, Nixon DF.

PLoS Pathog. 2008 Oct;4(10):e1000185. Epub 2008 Oct 24.PMID: 18949024 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence of oral disease among adults with primary HIV infection.

Owotade FJ, Shiboski CH, Poole L, Ramstead CA, Malvin K, Hecht FM, Greenspan JS.

Oral Dis. 2008 Sep;14(6):497-9.PMID: 18826380 [PubMed - indexed for MEDLINE]Related articles

Stimulant use is associated with immune activation and depleted tryptophan among HIV-positive persons on anti-retroviral therapy.

Carrico AW, Johnson MO, Morin SF, Remien RH, Riley ED, Hecht FM, Fuchs D.

Brain Behav Immun. 2008 Nov;22(8):1257-62. Epub 2008 Aug 3.PMID: 18703133 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance.

Liu L, May S, Richman DD, Hecht FM, Markowitz M, Daar ES, Routy JP, Margolick JB, Collier AC, Woelk CH, Little SJ, Smith DM.

AIDS. 2008 Apr 23;22(7):835-9.PMID: 18427201 [PubMed - indexed for MEDLINE]Related articlesFree article

CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1-infected individuals.

Ahuja SK, Kulkarni H, Catano G, Agan BK, Camargo JF, He W, O'Connell RJ, Marconi VC, Delmar J, Eron J, Clark RA, Frost S, Martin J, Ahuja SS, Deeks SG, Little S, Richman D, Hecht FM, Dolan MJ.

Nat Med. 2008 Apr;14(4):413-20. Epub 2008 Mar 30.PMID: 18376407 [PubMed - indexed for MEDLINE]Related articlesFree article

Conferral of enhanced natural killer cell function by KIR3DS1 in early human immunodeficiency virus type 1 infection.

Long BR, Ndhlovu LC, Oksenberg JR, Lanier LL, Hecht FM, Nixon DF, Barbour JD.

J Virol. 2008 May;82(10):4785-92. Epub 2008 Feb 27.PMID: 18305035 [PubMed - indexed for MEDLINE]Related articlesFree article

Immune reconstitution of CD56(dim) NK cells in individuals with primary HIV-1 infection treated with interleukin-2.

Michaëlsson J, Long BR, Loo CP, Lanier LL, Spotts G, Hecht FM, Nixon DF.

J Infect Dis. 2008 Jan 1;197(1):117-25.PMID: 18171294 [PubMed - indexed for MEDLINE]Related articles

Clinical presentation and diagnosis of primary HIV-1 infection.

Daar ES, Pilcher CD, Hecht FM.

Curr Opin HIV AIDS. 2008 Jan;3(1):10-15.PMID: 19372938 [PubMed - as supplied by publisher]Related articles

Elevated frequency of gamma interferon-producing NK cells in healthy adults vaccinated against influenza virus.

Long BR, Michaelsson J, Loo CP, Ballan WM, Vu BA, Hecht FM, Lanier LL, Chapman JM, Nixon DF.

Clin Vaccine Immunol. 2008 Jan;15(1):120-30. Epub 2007 Nov 14.PMID: 18003818 [PubMed - indexed for MEDLINE]Related articlesFree article

T cell responses to human endogenous retroviruses in HIV-1 infection.

Garrison KE, Jones RB, Meiklejohn DA, Anwar N, Ndhlovu LC, Chapman JM, Erickson AL, Agrawal A, Spotts G, Hecht FM, Rakoff-Nahoum S, Lenz J, Ostrowski MA, Nixon DF.

PLoS Pathog. 2007 Nov;3(11):e165.PMID: 17997601 [PubMed - indexed for MEDLINE]Related articlesFree article

FOXP3 expressing CD127lo CD4+ T cells inversely correlate with CD38+ CD8+ T cell activation levels in primary HIV-1 infection.

Ndhlovu LC, Loo CP, Spotts G, Nixon DF, Hecht FM.

J Leukoc Biol. 2008 Feb;83(2):254-62. Epub 2007 Nov 2.PMID: 17982112 [PubMed - indexed for MEDLINE]Related articlesFree article

CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms.

Dolan MJ, Kulkarni H, Camargo JF, He W, Smith A, Anaya JM, Miura T, Hecht FM, Mamtani M, Pereyra F, Marconi V, Mangano A, Sen L, Bologna R, Clark RA, Anderson SA, Delmar J, O'Connell RJ, Lloyd A, Martin J, Ahuja SS, Agan BK, Walker BD, Deeks SG, Ahuja SK.

Nat Immunol. 2007 Dec;8(12):1324-36. Epub 2007 Oct 21.PMID: 17952079 [PubMed - indexed for MEDLINE]Related articles

Loss of T cell responses following long-term cryopreservation.

Owen RE, Sinclair E, Emu B, Heitman JW, Hirschkorn DF, Epling CL, Tan QX, Custer B, Harris JM, Jacobson MA, McCune JM, Martin JN, Hecht FM, Deeks SG, Norris PJ.

J Immunol Methods. 2007 Sep 30;326(1-2):93-115. Epub 2007 Aug 8.PMID: 17707394 [PubMed - indexed for MEDLINE]Related articlesFree article

Antiretroviral drug therapy alters the profile of human immunodeficiency virus type 1-specific T-cell responses and shifts the immunodominant cytotoxic T-lymphocyte response from Gag to Pol.

Karlsson AC, Chapman JM, Heiken BD, Hoh R, Kallas EG, Martin JN, Hecht FM, Deeks SG, Nixon DF.

J Virol. 2007 Oct;81(20):11543-8. Epub 2007 Aug 1.PMID: 17670829 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative longitudinal analysis of T cell receptor repertoire expression in HIV-infected patients on antiretroviral and interleukin-2 therapy.

Sriram U, Wong M, Caillier SJ, Hecht FM, Elkins MK, Levy JA, Oksenberg JR, Baranzini SE.

AIDS Res Hum Retroviruses. 2007 May;23(5):741-7.PMID: 17531001 [PubMed - indexed for MEDLINE]Related articles

Frequent detection of the parvoviruses, PARV4 and PARV5, in plasma from blood donors and symptomatic individuals.

Fryer JF, Delwart E, Hecht FM, Bernardin F, Jones MS, Shah N, Baylis SA.

Transfusion. 2007 Jun;47(6):1054-61. Erratum in: Transfusion. 2007 Aug;47(8):1559. PMID: 17524097 [PubMed - indexed for MEDLINE]Related articles

The relation between symptoms, viral load, and viral load set point in primary HIV infection.

Kelley CF, Barbour JD, Hecht FM.

J Acquir Immune Defic Syndr. 2007 Aug 1;45(4):445-8.PMID: 17514014 [PubMed - indexed for MEDLINE]Related articles

Synergy or independence? Deciphering the interaction of HLA Class I and NK cell KIR alleles in early HIV-1 disease progression.

Barbour JD, Sriram U, Caillier SJ, Levy JA, Hecht FM, Oksenberg JR.

PLoS Pathog. 2007 Apr;3(4):e43. Review. No abstract available. Erratum in: PLoS Pathog. 2007 Oct 12;3(10):1540. PLoS Pathog. 2007 Oct;3(10):e154. PMID: 17447840 [PubMed - indexed for MEDLINE]Related articlesFree article

Lessons from an HIV transmission pair.

Hecht FM, Wolf LE, Lo B.

J Infect Dis. 2007 May 1;195(9):1239-41. Epub 2007 Mar 21. No abstract available. PMID: 17396989 [PubMed - indexed for MEDLINE]Related articles

Human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T(EMRA) cells in early infection are linked to control of HIV-1 viremia and predict the subsequent viral load set point.

Northfield JW, Loo CP, Barbour JD, Spotts G, Hecht FM, Klenerman P, Nixon DF, Michaëlsson J.

J Virol. 2007 Jun;81(11):5759-65. Epub 2007 Mar 21.PMID: 17376902 [PubMed - indexed for MEDLINE]Related articlesFree article

Symptom management with massage and acupuncture in postoperative cancer patients: a randomized controlled trial.

Mehling WE, Jacobs B, Acree M, Wilson L, Bostrom A, West J, Acquah J, Burns B, Chapman J, Hecht FM.

J Pain Symptom Manage. 2007 Mar;33(3):258-66.PMID: 17349495 [PubMed - indexed for MEDLINE]Related articles

Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape.

Karlsson AC, Iversen AK, Chapman JM, de Oliviera T, Spotts G, McMichael AJ, Davenport MP, Hecht FM, Nixon DF.

PLoS One. 2007 Feb 21;2(2):e225.PMID: 17311088 [PubMed]Related articlesFree article

Frequent methamphetamine use is associated with primary non-nucleoside reverse transcriptase inhibitor resistance.

Colfax GN, Vittinghoff E, Grant R, Lum P, Spotts G, Hecht FM.

AIDS. 2007 Jan 11;21(2):239-41.PMID: 17197817 [PubMed - indexed for MEDLINE]Related articles

Physicians' communication with patients about adherence to HIV medication in San Francisco and Copenhagen: a qualitative study using Grounded Theory.

Barfod TS, Hecht FM, Rubow C, Gerstoft J.

BMC Health Serv Res. 2006 Dec 4;6:154.PMID: 17144910 [PubMed - indexed for MEDLINE]Related articlesFree article

Microbial translocation is a cause of systemic immune activation in chronic HIV infection.

Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC.

Nat Med. 2006 Dec;12(12):1365-71. Epub 2006 Nov 19.PMID: 17115046 [PubMed - indexed for MEDLINE]Related articles

Greater CD4 T-cell gains after one year of antiretroviral therapy are associated with lower HIV-1 pol replication capacity.

Barbour JD, Hecht FM, Little SJ, Markowitz M, Daar ES, Kelleher AD, Routy JP, Campbell TB, Rosenberg ES, Segal MR, Weidler J, Grant RM.

AIDS. 2006 Oct 24;20(16):2123-5.PMID: 17053362 [PubMed - indexed for MEDLINE]Related articles

Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo.

Zimmerman ES, Sherman MP, Blackett JL, Neidleman JA, Kreis C, Mundt P, Williams SA, Warmerdam M, Kahn J, Hecht FM, Grant RM, de Noronha CM, Weyrich AS, Greene WC, Planelles V.

J Virol. 2006 Nov;80(21):10407-18. Epub 2006 Sep 6.PMID: 16956949 [PubMed - indexed for MEDLINE]Related articlesFree article

A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection.

Hecht FM, Wang L, Collier A, Little S, Markowitz M, Margolick J, Kilby JM, Daar E, Conway B, Holte S; AIEDRP Network.

J Infect Dis. 2006 Sep 15;194(6):725-33. Epub 2006 Aug 15.PMID: 16941337 [PubMed - indexed for MEDLINE]Related articles

Elevations in IL-10, TNF-alpha, and IFN-gamma from the earliest point of HIV Type 1 infection.

Norris PJ, Pappalardo BL, Custer B, Spotts G, Hecht FM, Busch MP.

AIDS Res Hum Retroviruses. 2006 Aug;22(8):757-62.PMID: 16910831 [PubMed - indexed for MEDLINE]Related articlesFree article

A piece of my mind. The CBC.

Hecht FM.

JAMA. 2006 Jul 12;296(2):149-50. No abstract available. PMID: 16835410 [PubMed - indexed for MEDLINE]Related articles

The effects of early antiretroviral therapy and its discontinuation on the HIV-specific antibody response.

Killian MS, Norris PJ, Rawal BD, Lebedeva M, Hecht FM, Levy JA, Busch MP.

AIDS Res Hum Retroviruses. 2006 Jul;22(7):640-7.PMID: 16831088 [PubMed - indexed for MEDLINE]Related articles

Similar changes in plasmacytoid dendritic cell and CD4 T-cell counts during primary HIV-1 infection and treatment.

Killian MS, Fujimura SH, Hecht FM, Levy JA.

AIDS. 2006 Jun 12;20(9):1247-52.PMID: 16816552 [PubMed - indexed for MEDLINE]Related articles

Neutralizing antibody responses against autologous and heterologous viruses in acute versus chronic human immunodeficiency virus (HIV) infection: evidence for a constraint on the ability of HIV to completely evade neutralizing antibody responses.

Deeks SG, Schweighardt B, Wrin T, Galovich J, Hoh R, Sinclair E, Hunt P, McCune JM, Martin JN, Petropoulos CJ, Hecht FM.

J Virol. 2006 Jun;80(12):6155-64.PMID: 16731954 [PubMed - indexed for MEDLINE]Related articlesFree article

Newly diagnosed HIV infection.

Chin-Hong PV, Hecht FM, Klausner JD.

N Engl J Med. 2006 Feb 16;354(7):771-2; author reply 771-2. No abstract available. PMID: 16481652 [PubMed - indexed for MEDLINE]Related articles

Seroreversion in subjects receiving antiretroviral therapy during acute/early HIV infection.

Hare CB, Pappalardo BL, Busch MP, Karlsson AC, Phelps BH, Alexander SS, Bentsen C, Ramstead CA, Nixon DF, Levy JA, Hecht FM.

Clin Infect Dis. 2006 Mar 1;42(5):700-8. Epub 2006 Jan 23.PMID: 16447118 [PubMed - indexed for MEDLINE]Related articles

Expansion of CD1d-restricted NKT cells in patients with primary HIV-1 infection treated with interleukin-2.

Moll M, Snyder-Cappione J, Spotts G, Hecht FM, Sandberg JK, Nixon DF.

Blood. 2006 Apr 15;107(8):3081-3. Epub 2005 Dec 20.PMID: 16368878 [PubMed - indexed for MEDLINE]Related articlesFree article

Seroconversion following nonoccupational postexposure prophylaxis against HIV.

Roland ME, Neilands TB, Krone MR, Katz MH, Franses K, Grant RM, Busch MP, Hecht FM, Shacklett BL, Kahn JO, Bamberger JD, Coates TJ, Chesney MA, Martin JN.

Clin Infect Dis. 2005 Nov 15;41(10):1507-13. Epub 2005 Oct 13.PMID: 16231265 [PubMed - indexed for MEDLINE]Related articles