PubMed

It's a free for all--insulin-positive cells join the group of potential progenitors for pancreatic ductal adenocarcinoma.

Morris JP 4th, Hebrok M.

Cancer Cell. 2009 Nov 6;16(5):359-61.PMID: 19878864 [PubMed - in process]Related articles

Dicer is required for proper liver zonation.

Sekine S, Ogawa R, Mcmanus MT, Kanai Y, Hebrok M.

J Pathol. 2009 Nov;219(3):365-72.PMID: 19718708 [PubMed - in process]Related articles

Stem cells to pancreatic beta-cells: new sources for diabetes cell therapy.

Guo T, Hebrok M.

Endocr Rev. 2009 May;30(3):214-27. Epub 2009 Apr 23. Review.PMID: 19389995 [PubMed - indexed for MEDLINE]Related articles

Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis.

Sekine S, Ogawa R, Ito R, Hiraoka N, McManus MT, Kanai Y, Hebrok M.

Gastroenterology. 2009 Jun;136(7):2304-2315.e1-4. Epub 2009 Mar 6.PMID: 19272382 [PubMed - indexed for MEDLINE]Related articles

GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation.

Nolan-Stevaux O, Lau J, Truitt ML, Chu GC, Hebrok M, Fernández-Zapico ME, Hanahan D.

Genes Dev. 2009 Jan 1;23(1):24-36.PMID: 19136624 [PubMed - indexed for MEDLINE]Related articlesFree article

Wnt5a is essential for intestinal elongation in mice.

Cervantes S, Yamaguchi TP, Hebrok M.

Dev Biol. 2009 Feb 15;326(2):285-94. Epub 2008 Dec 7.PMID: 19100728 [PubMed - indexed for MEDLINE]Related articles

A role for von Hippel-Lindau protein in pancreatic beta-cell function.

Puri S, Cano DA, Hebrok M.

Diabetes. 2009 Feb;58(2):433-41. Epub 2008 Nov 25.PMID: 19033400 [PubMed - indexed for MEDLINE]Related articlesFree article

Stabilization of beta-catenin induces pancreas tumor formation.

Heiser PW, Cano DA, Landsman L, Kim GE, Kench JG, Klimstra DS, Taketo MM, Biankin AV, Hebrok M.

Gastroenterology. 2008 Oct;135(4):1288-300. Epub 2008 Jul 9.PMID: 18725219 [PubMed - indexed for MEDLINE]Related articlesFree article

Hedgehog spikes pancreas regeneration.

Cano DA, Hebrok M.

Gastroenterology. 2008 Aug;135(2):347-51. Epub 2008 Jul 11. No abstract available. PMID: 18619970 [PubMed - indexed for MEDLINE]Related articles

Safer, longer-lasting regulatory T cells with beta-catenin.

Bluestone JA, Hebrok M.

Nat Med. 2008 Feb;14(2):118-9. No abstract available. PMID: 18256611 [PubMed - indexed for MEDLINE]Related articles

Regulated beta-cell regeneration in the adult mouse pancreas.

Cano DA, Rulifson IC, Heiser PW, Swigart LB, Pelengaris S, German M, Evan GI, Bluestone JA, Hebrok M.

Diabetes. 2008 Apr;57(4):958-66. Epub 2007 Dec 14.PMID: 18083786 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic innervation in mouse development and beta-cell regeneration.

Burris RE, Hebrok M.

Neuroscience. 2007 Dec 12;150(3):592-602. Epub 2007 Oct 11.PMID: 18006238 [PubMed - indexed for MEDLINE]Related articlesFree article

Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.

Regard JB, Kataoka H, Cano DA, Camerer E, Yin L, Zheng YW, Scanlan TS, Hebrok M, Coughlin SR.

J Clin Invest. 2007 Dec;117(12):4034-43.PMID: 17992256 [PubMed - indexed for MEDLINE]Related articlesFree article

Common activation of canonical Wnt signaling in pancreatic adenocarcinoma.

Pasca di Magliano M, Biankin AV, Heiser PW, Cano DA, Gutierrez PJ, Deramaudt T, Segara D, Dawson AC, Kench JG, Henshall SM, Sutherland RL, Dlugosz A, Rustgi AK, Hebrok M.

PLoS One. 2007 Nov 7;2(11):e1155.PMID: 17982507 [PubMed - indexed for MEDLINE]Related articlesFree article

A small-molecule antagonist of the hedgehog signaling pathway.

Lee J, Wu X, Pasca di Magliano M, Peters EC, Wang Y, Hong J, Hebrok M, Ding S, Cho CY, Schultz PG.

Chembiochem. 2007 Nov 5;8(16):1916-9. No abstract available. PMID: 17886323 [PubMed - indexed for MEDLINE]Related articles

Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells.

Nawroth R, van Zante A, Cervantes S, McManus M, Hebrok M, Rosen SD.

PLoS One. 2007 Apr 25;2(4):e392.PMID: 17460759 [PubMed]Related articlesFree article

Dynamics of embryonic pancreas development using real-time imaging.

Puri S, Hebrok M.

Dev Biol. 2007 Jun 1;306(1):82-93. Epub 2007 Mar 12.PMID: 17448459 [PubMed - indexed for MEDLINE]Related articlesFree article

Hedgehogs: la dolce vita. Workshop on Hedgehog-Gli Signaling in Cancer and Stem Cells.

Robbins DJ, Hebrok M.

EMBO Rep. 2007 May;8(5):451-5. Epub 2007 Apr 13. No abstract available. PMID: 17431408 [PubMed - indexed for MEDLINE]Related articlesFree article

Wnt signaling regulates pancreatic beta cell proliferation.

Rulifson IC, Karnik SK, Heiser PW, ten Berge D, Chen H, Gu X, Taketo MM, Nusse R, Hebrok M, Kim SK.

Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6247-52. Epub 2007 Apr 2.PMID: 17404238 [PubMed - indexed for MEDLINE]Related articlesFree article

Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis.

Morton JP, Mongeau ME, Klimstra DS, Morris JP, Lee YC, Kawaguchi Y, Wright CV, Hebrok M, Lewis BC.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5103-8. Epub 2007 Mar 19.PMID: 17372229 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic development and disease.

Cano DA, Hebrok M, Zenker M.

Gastroenterology. 2007 Feb;132(2):745-62. Review. No abstract available. PMID: 17258745 [PubMed - indexed for MEDLINE]Related articles

Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy.

Sekine S, Gutiérrez PJ, Lan BY, Feng S, Hebrok M.

Hepatology. 2007 Feb;45(2):361-8.PMID: 17256747 [PubMed - indexed for MEDLINE]Related articles

Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis.

Cano DA, Sekine S, Hebrok M.

Gastroenterology. 2006 Dec;131(6):1856-69. Epub 2006 Oct 26.PMID: 17123526 [PubMed - indexed for MEDLINE]Related articles

Hedgehog/Ras interactions regulate early stages of pancreatic cancer.

Pasca di Magliano M, Sekine S, Ermilov A, Ferris J, Dlugosz AA, Hebrok M.

Genes Dev. 2006 Nov 15;20(22):3161-73.PMID: 17114586 [PubMed - indexed for MEDLINE]Related articlesFree article

Stabilization of beta-catenin impacts pancreas growth.

Heiser PW, Lau J, Taketo MM, Herrera PL, Hebrok M.

Development. 2006 May;133(10):2023-32. Epub 2006 Apr 12.PMID: 16611688 [PubMed - indexed for MEDLINE]Related articlesFree article

Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice.

Sekine S, Lan BY, Bedolli M, Feng S, Hebrok M.

Hepatology. 2006 Apr;43(4):817-25.PMID: 16557553 [PubMed - indexed for MEDLINE]Related articles

Hedgehog signaling in pancreas development and disease.

Lau J, Kawahira H, Hebrok M.

Cell Mol Life Sci. 2006 Mar;63(6):642-52. Review.PMID: 16465449 [PubMed - indexed for MEDLINE]Related articles

Hedgehog signaling regulates expansion of pancreatic epithelial cells.

Kawahira H, Scheel DW, Smith SB, German MS, Hebrok M.

Dev Biol. 2005 Apr 1;280(1):111-21.PMID: 15766752 [PubMed - indexed for MEDLINE]Related articles

Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo.

Perez SE, Cano DA, Dao-Pick T, Rougier JP, Werb Z, Hebrok M.

Diabetes. 2005 Mar;54(3):694-701.PMID: 15734845 [PubMed - indexed for MEDLINE]Related articlesFree article

Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization.

Cano DA, Murcia NS, Pazour GJ, Hebrok M.

Development. 2004 Jul;131(14):3457-67.PMID: 15226261 [PubMed - indexed for MEDLINE]Related articlesFree article

Brain meets pancreas: netrin, an axon guidance molecule, controls epithelial cell migration.

Hebrok M, Reichardt LF.

Trends Cell Biol. 2004 Apr;14(4):153-5. Review.PMID: 15134068 [PubMed - indexed for MEDLINE]Related articlesFree article

Hedgehog signalling in cancer formation and maintenance.

Pasca di Magliano M, Hebrok M.

Nat Rev Cancer. 2003 Dec;3(12):903-11. Review. No abstract available. PMID: 14737121 [PubMed - indexed for MEDLINE]Related articles

Development and cancer: lessons learned in the pancreas.

Heiser PW, Hebrok M.

Cell Cycle. 2004 Mar;3(3):270-2. Epub 2004 Mar 1.PMID: 14726662 [PubMed - indexed for MEDLINE]Related articlesFree article

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis.

Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernández-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL, Hebrok M.

Nature. 2003 Oct 23;425(6960):851-6. Epub 2003 Sep 14.PMID: 14520413 [PubMed - indexed for MEDLINE]Related articles

Combined activities of hedgehog signaling inhibitors regulate pancreas development.

Kawahira H, Ma NH, Tzanakakis ES, McMahon AP, Chuang PT, Hebrok M.

Development. 2003 Oct;130(20):4871-9. Epub 2003 Aug 13.PMID: 12917290 [PubMed - indexed for MEDLINE]Related articlesFree article

Hedgehog signaling in pancreas development.

Hebrok M.

Mech Dev. 2003 Jan;120(1):45-57. Review.PMID: 12490295 [PubMed - indexed for MEDLINE]Related articles

Intercellular signals regulating pancreas development and function.

Kim SK, Hebrok M.

Genes Dev. 2001 Jan 15;15(2):111-27. Review. No abstract available. PMID: 11157769 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of pancreas development by hedgehog signaling.

Hebrok M, Kim SK, St Jacques B, McMahon AP, Melton DA.

Development. 2000 Nov;127(22):4905-13.PMID: 11044404 [PubMed - indexed for MEDLINE]Related articlesFree article

Activin receptor patterning of foregut organogenesis.

Kim SK, Hebrok M, Li E, Oh SP, Schrewe H, Harmon EB, Lee JS, Melton DA.

Genes Dev. 2000 Aug 1;14(15):1866-71.PMID: 10921901 [PubMed - indexed for MEDLINE]Related articlesFree article

Screening for novel pancreatic genes expressed during embryogenesis.

Hebrok M, Kim SK, Melton DA.

Diabetes. 1999 Aug;48(8):1550-6.PMID: 10426372 [PubMed - indexed for MEDLINE]Related articlesFree article

Notochord repression of endodermal Sonic hedgehog permits pancreas development.

Hebrok M, Kim SK, Melton DA.

Genes Dev. 1998 Jun 1;12(11):1705-13.PMID: 9620856 [PubMed - indexed for MEDLINE]Related articlesFree article

Notochord to endoderm signaling is required for pancreas development.

Kim SK, Hebrok M, Melton DA.

Development. 1997 Nov;124(21):4243-52.PMID: 9334273 [PubMed - indexed for MEDLINE]Related articlesFree article

Repression of muscle-specific gene activation by the murine Twist protein.

Hebrok M, Füchtbauer A, Füchtbauer EM.

Exp Cell Res. 1997 May 1;232(2):295-303.PMID: 9168805 [PubMed - indexed for MEDLINE]Related articles

Pancreas development in the chick embryo.

Kim SK, Hebrok M, Melton DA.

Cold Spring Harb Symp Quant Biol. 1997;62:377-83. No abstract available. PMID: 9598372 [PubMed - indexed for MEDLINE]Related articles

M-twist expression inhibits mouse embryonic stem cell-derived myogenic differentiation in vitro.

Rohwedel J, Horák V, Hebrok M, Füchtbauer EM, Wobus AM.

Exp Cell Res. 1995 Sep;220(1):92-100.PMID: 7664846 [PubMed - indexed for MEDLINE]Related articles

M-twist is an inhibitor of muscle differentiation.

Hebrok M, Wertz K, Füchtbauer EM.

Dev Biol. 1994 Oct;165(2):537-44.PMID: 7958419 [PubMed - indexed for MEDLINE]Related articles