PubMed

Differential protein profiling as a potential multi -marker approach for TSE diagnosis.

Barr JB, Watson M, Head MW, Ironside JW, Harris N, Hogarth C, Fraser JR, Barron R.

BMC Infect Dis. 2009 Nov 27;9(1):188. [Epub ahead of print]PMID: 19943924 [PubMed - as supplied by publisher]

Sporadic Creutzfeldt-Jakob disease: discrete subtypes or a spectrum of disease?

Head MW, Ironside JW.

Brain. 2009 Oct;132(Pt 10):2627-9. Epub 2009 Sep 16. No abstract available. PMID: 19759201 [PubMed - in process]Related articles

A case of protease sensitive prionopathy in a patient in the UK.

Head MW, Knight R, Zeidler M, Yull H, Barlow A, Ironside JW.

Neuropathol Appl Neurobiol. 2009 Dec;35(6):628-32. Epub 2009 Aug 7. No abstract available. PMID: 19671081 [PubMed - in process]Related articles

Transmissions of variant Creutzfeldt-Jakob disease from brain and lymphoreticular tissue show uniform and conserved bovine spongiform encephalopathy-related phenotypic properties on primary and secondary passage in wild-type mice.

Ritchie DL, Boyle A, McConnell I, Head MW, Ironside JW, Bruce ME.

J Gen Virol. 2009 Dec;90(Pt 12):3075-82. Epub 2009 Aug 5.PMID: 19656962 [PubMed - in process]Related articles

Pathological investigation of the first blood donor and recipient pair linked by transfusion-associated variant Creutzfeldt-Jakob disease transmission.

Head MW, Yull HM, Ritchie DL, Bishop MT, Ironside JW.

Neuropathol Appl Neurobiol. 2009 Aug;35(4):433-6. Epub 2009 Apr 7. No abstract available. PMID: 19490428 [PubMed - indexed for MEDLINE]Related articles

Panencephalopathic Creutzfeldt-Jakob disease in the Netherlands and the UK: clinical and pathological characteristics of nine patients.

Jansen C, Head MW, Rozemuller AJ, Ironside JW.

Neuropathol Appl Neurobiol. 2009 Jun;35(3):272-82.PMID: 19473294 [PubMed - indexed for MEDLINE]Related articles

Variant Creutzfeldt-Jakob disease in France and the United Kingdom: Evidence for the same agent strain.

Brandel JP, Heath CA, Head MW, Levavasseur E, Knight R, Laplanche JL, Langeveld JP, Ironside JW, Hauw JJ, Mackenzie J, Alpérovitch A, Will RG, Haïk S.

Ann Neurol. 2009 Mar;65(3):249-56.PMID: 19334063 [PubMed - indexed for MEDLINE]Related articles

Further characterisation of the prion protein molecular types detectable in the NIBSC Creutzfeldt-Jakob disease brain reference materials.

Yull HM, Ironside JW, Head MW.

Biologicals. 2009 Aug;37(4):210-5. Epub 2009 Mar 4.PMID: 19264507 [PubMed - in process]Related articles

Familial prion disease with a novel serine to isoleucine mutation at codon 132 of prion protein gene (PRNP).

Hilton DA, Head MW, Singh VK, Bishop M, Ironside JW.

Neuropathol Appl Neurobiol. 2009 Feb;35(1):111-5. No abstract available. PMID: 19187063 [PubMed - indexed for MEDLINE]Related articles

Production and characterization of a panel of monoclonal antibodies against native human cellular prion protein.

Jones M, McLoughlin V, Connolly JG, Farquhar CF, Macgregor IR, Head MW.

Hybridoma (Larchmt). 2009 Feb;28(1):13-20.PMID: 19132894 [PubMed - in process]Related articles

Panencephalopathic Creutzfeldt-Jakob disease in the Netherlands and UK: clinical and pathological characteristics of nine patients.

Jansen C, Head MW, Rozemuller AJ, Ironside JW.

Neuropathol Appl Neurobiol. 2008 Dec 1. [Epub ahead of print]PMID: 19055524 [PubMed - as supplied by publisher]Related articles

Human platelets as a substrate source for the in vitro amplification of the abnormal prion protein (PrP) associated with variant Creutzfeldt-Jakob disease.

Jones M, Peden AH, Yull H, Wight D, Bishop MT, Prowse CV, Turner ML, Ironside JW, MacGregor IR, Head MW.

Transfusion. 2009 Feb;49(2):376-84. Epub 2008 Oct 29.PMID: 18980616 [PubMed - indexed for MEDLINE]Related articles

Effects of human PrPSc type and PRNP genotype in an in-vitro conversion assay.

Jones M, Peden AH, Wight D, Prowse C, Macgregor I, Manson J, Turner M, Ironside JW, Head MW.

Neuroreport. 2008 Dec 3;19(18):1783-6.PMID: 18955905 [PubMed - indexed for MEDLINE]Related articles

No major change in vCJD agent strain after secondary transmission via blood transfusion.

Bishop MT, Ritchie DL, Will RG, Ironside JW, Head MW, Thomson V, Bruce M, Manson JC.

PLoS One. 2008 Aug 6;3(8):e2878.PMID: 18682737 [PubMed - indexed for MEDLINE]Related articlesFree article

Biology and neuropathology of prion diseases.

Ironside JW, Head MW.

Handb Clin Neurol. 2008;89:779-97. No abstract available. PMID: 18631794 [PubMed - in process]Related articles

Inter-laboratory assessment of PrPSc typing in creutzfeldt-jakob disease: a Western blot study within the NeuroPrion Consortium.

Parchi P, Notari S, Weber P, Schimmel H, Budka H, Ferrer I, Haik S, Hauw JJ, Head MW, Ironside JW, Limido L, Rodriguez A, Ströbel T, Tagliavini F, Kretzschmar HA.

Brain Pathol. 2009 Jul;19(3):384-91. Epub 2008 Jul 2.PMID: 18624793 [PubMed - indexed for MEDLINE]Related articles

An antibody to the aggregated synthetic prion protein peptide (PrP106-126) selectively recognizes disease-associated prion protein (PrP) from human brain specimens.

Jones M, Wight D, McLoughlin V, Norrby K, Ironside JW, Connolly JG, Farquhar CF, MacGregor IR, Head MW.

Brain Pathol. 2009 Apr;19(2):293-302. Epub 2008 May 26.PMID: 18507665 [PubMed - indexed for MEDLINE]Related articles

Beyond PrP9res) type 1/type 2 dichotomy in Creutzfeldt-Jakob disease.

Uro-Coste E, Cassard H, Simon S, Lugan S, Bilheude JM, Perret-Liaudet A, Ironside JW, Haik S, Basset-Leobon C, Lacroux C, Peoch' K, Streichenberger N, Langeveld J, Head MW, Grassi J, Hauw JJ, Schelcher F, Delisle MB, Andréoletti O.

PLoS Pathog. 2008 Mar 14;4(3):e1000029.PMID: 18389084 [PubMed - indexed for MEDLINE]Related articlesFree article

Beyond PrP res type 1/type 2 dichotomy in Creutzfeldt-Jakob disease.

Uro-Coste E, Cassard H, Simon S, Lugan S, Bilheude JM, Perret-Liaudet A, Ironside JW, Haik S, Basset-Leobon C, Lacroux C, Peoch K, Streichenberger N, Langeveld J, Head MW, Grassi J, Hauw JJ, Schelcher F, Delisle MB, Andréoletti O.

PLoS Pathog. 2008 Mar;4(3):e1000029.PMID: 18383623 [PubMed - indexed for MEDLINE]Related articles

Disease-associated prion protein is not detectable in human systemic amyloid deposits.

Tennent GA, Head MW, Bishop M, Hawkins PN, Will RG, Knight R, Peden AH, McCardle LM, Ironside JW, Pepys MB.

J Pathol. 2007 Dec;213(4):376-83.PMID: 17955450 [PubMed - indexed for MEDLINE]Related articles

Application of Atomic Dielectric Resonance Spectroscopy for the screening of blood samples from patients with clinical variant and sporadic CJD.

Fagge TJ, Barclay GR, Stove GC, Stove G, Robinson MJ, Head MW, Ironside JW, Turner ML.

J Transl Med. 2007 Aug 30;5:41.PMID: 17760958 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro amplification and detection of variant Creutzfeldt-Jakob disease PrPSc.

Jones M, Peden AH, Prowse CV, Gröner A, Manson JC, Turner ML, Ironside JW, MacGregor IR, Head MW.

J Pathol. 2007 Sep;213(1):21-6.PMID: 17614097 [PubMed - indexed for MEDLINE]Related articles

Abnormal prion protein in the pituitary in sporadic and variant Creutzfeldt-Jakob disease.

Peden AH, Ritchie DL, Uddin HP, Dean AF, Schiller KA, Head MW, Ironside JW.

J Gen Virol. 2007 Mar;88(Pt 3):1068-72.PMID: 17325383 [PubMed - indexed for MEDLINE]Related articlesFree article

vCJD and the gut: implications for endoscopy.

Head MW, Ironside JW.

Gut. 2007 Jan;56(1):9-11. Review. No abstract available. PMID: 17172584 [PubMed - indexed for MEDLINE]Related articles

Transplantation of ocular tissue from a donor with sporadic Creutzfeldt-Jakob disease.

Tullo AB, Buckley RJ, Kelly T, Head MW, Bennett P, Armitage WJ, Ironside JW.

Clin Experiment Ophthalmol. 2006 Sep-Oct;34(7):645-9.PMID: 16970756 [PubMed - indexed for MEDLINE]Related articles

Application of an immunocapillary electrophoresis assay to the detection of abnormal prion protein in brain, spleen and blood specimens from patients with variant Creutzfeldt-Jakob disease.

Lourenco PC, Schmerr MJ, MacGregor I, Will RG, Ironside JW, Head MW.

J Gen Virol. 2006 Oct;87(Pt 10):3119-24.PMID: 16963772 [PubMed - indexed for MEDLINE]Related articlesFree article

Sporadic Creutzfeldt-Jakob disease: further twists and turns in a convoluted protein.

Head MW, Ironside JW.

Brain. 2006 Sep;129(Pt 9):2238-40. No abstract available. PMID: 16923953 [PubMed - indexed for MEDLINE]Related articlesFree article

Predicting susceptibility and incubation time of human-to-human transmission of vCJD.

Bishop MT, Hart P, Aitchison L, Baybutt HN, Plinston C, Thomson V, Tuzi NL, Head MW, Ironside JW, Will RG, Manson JC.

Lancet Neurol. 2006 May;5(5):393-8.PMID: 16632309 [PubMed - indexed for MEDLINE]Related articles

Dura mater-associated Creutzfeldt-Jakob disease: experience from surveillance in the UK.

Heath CA, Barker RA, Esmonde TF, Harvey P, Roberts R, Trend P, Head MW, Smith C, Bell JE, Ironside JW, Will RG, Knight RS.

J Neurol Neurosurg Psychiatry. 2006 Jul;77(7):880-2. Epub 2006 Apr 20.PMID: 16627534 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection and localization of PrPSc in the skeletal muscle of patients with variant, iatrogenic, and sporadic forms of Creutzfeldt-Jakob disease.

Peden AH, Ritchie DL, Head MW, Ironside JW.

Am J Pathol. 2006 Mar;168(3):927-35.PMID: 16507908 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection of type 1 prion protein in variant Creutzfeldt-Jakob disease.

Yull HM, Ritchie DL, Langeveld JP, van Zijderveld FG, Bruce ME, Ironside JW, Head MW.

Am J Pathol. 2006 Jan;168(1):151-7.PMID: 16400018 [PubMed - indexed for MEDLINE]Related articlesFree article

Raised CSF phospho-tau concentrations in variant Creutzfeldt-Jakob disease: diagnostic and pathological implications.

Goodall CA, Head MW, Everington D, Ironside JW, Knight RS, Green AJ.

J Neurol Neurosurg Psychiatry. 2006 Jan;77(1):89-91.PMID: 16361602 [PubMed - indexed for MEDLINE]Related articlesFree article

Phenotypic variability in human prion diseases.

Ironside JW, Ritchie DL, Head MW.

Neuropathol Appl Neurobiol. 2005 Dec;31(6):565-79. Review.PMID: 16281905 [PubMed - indexed for MEDLINE]Related articles

Abnormal prion protein in the retina of the most commonly occurring subtype of sporadic Creutzfeldt-Jakob disease.

Head MW, Peden AH, Yull HM, Ritchie DL, Bonshek RE, Tullo AB, Ironside JW.

Br J Ophthalmol. 2005 Sep;89(9):1131-3.PMID: 16113366 [PubMed - indexed for MEDLINE]Related articlesFree article

Purification of normal cellular prion protein from human platelets and the formation of a high molecular weight prion protein complex following platelet activation.

Jones M, Head MW, Connolly JG, Farquhar CF, Hornsey VS, Pepper DS, MacGregor IR.

Biochem Biophys Res Commun. 2005 Sep 16;335(1):48-56.PMID: 16051190 [PubMed - indexed for MEDLINE]Related articles

Evaluation of urinary PrPSc as a diagnostic test for sporadic, variant, and familial CJD.

Head MW, Kouverianou E, Taylor L, Green A, Knight R.

Neurology. 2005 May 24;64(10):1794-6.PMID: 15911815 [PubMed - indexed for MEDLINE]Related articles

Mad cows and monkey business: the end of vCJD?

Head MW, Ironside JW.

Lancet. 2005 Feb 26-Mar 4;365(9461):730-1. No abstract available. PMID: 15733699 [PubMed - indexed for MEDLINE]Related articles

Variant Creutzfeldt-Jakob disease: risk of transmission by blood and blood products.

Ironside JW, Head MW.

Haemophilia. 2004 Oct;10 Suppl 4:64-9. Review.PMID: 15479374 [PubMed - indexed for MEDLINE]Related articles

Advances in the detection of prion protein in peripheral tissues of variant Creutzfeldt-Jakob disease patients using paraffin-embedded tissue blotting.

Ritchie DL, Head MW, Ironside JW.

Neuropathol Appl Neurobiol. 2004 Aug;30(4):360-8.PMID: 15305981 [PubMed - indexed for MEDLINE]Related articles

Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient.

Peden AH, Head MW, Ritchie DL, Bell JE, Ironside JW.

Lancet. 2004 Aug 7-13;364(9433):527-9.PMID: 15302196 [PubMed - indexed for MEDLINE]Related articles

Prion protein accumulation and neuroprotection in hypoxic brain damage.

McLennan NF, Brennan PM, McNeill A, Davies I, Fotheringham A, Rennison KA, Ritchie D, Brannan F, Head MW, Ironside JW, Williams A, Bell JE.

Am J Pathol. 2004 Jul;165(1):227-35.PMID: 15215178 [PubMed - indexed for MEDLINE]Related articlesFree article

Prion protein heterogeneity in sporadic but not variant Creutzfeldt-Jakob disease: UK cases 1991-2002.

Head MW, Bunn TJ, Bishop MT, McLoughlin V, Lowrie S, McKimmie CS, Williams MC, McCardle L, MacKenzie J, Knight R, Will RG, Ironside JW.

Ann Neurol. 2004 Jun;55(6):851-9.PMID: 15174020 [PubMed - indexed for MEDLINE]Related articles

Neuropathology and molecular biology of variant Creutzfeldt-Jakob disease.

Ironside JW, Head MW.

Curr Top Microbiol Immunol. 2004;284:133-59. Review.PMID: 15148991 [PubMed - indexed for MEDLINE]Related articles

Specificity of lymphoreticular accumulation of prion protein for variant Creutzfeldt-Jakob disease.

Hilton DA, Sutak J, Smith ME, Penney M, Conyers L, Edwards P, McCardle L, Ritchie D, Head MW, Wiley CA, Ironside JW.

J Clin Pathol. 2004 Mar;57(3):300-2.PMID: 14990604 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral tissue involvement in sporadic, iatrogenic, and variant Creutzfeldt-Jakob disease: an immunohistochemical, quantitative, and biochemical study.

Head MW, Ritchie D, Smith N, McLoughlin V, Nailon W, Samad S, Masson S, Bishop M, McCardle L, Ironside JW.

Am J Pathol. 2004 Jan;164(1):143-53.PMID: 14695328 [PubMed - indexed for MEDLINE]Related articlesFree article

Investigation of PrPres in dental tissues in variant CJD.

Head MW, Ritchie D, McLoughlin V, Ironside JW.

Br Dent J. 2003 Sep 27;195(6):339-43; discussion 331.PMID: 14513001 [PubMed - indexed for MEDLINE]Related articles

Variant Creutzfeldt-Jakob disease and its transmission by blood.

Ironside JW, Head MW.

J Thromb Haemost. 2003 Jul;1(7):1479-86. Review.PMID: 12871283 [PubMed - indexed for MEDLINE]Related articles

Variant Creutzfeldt-Jakob disease.

Ward HJ, Head MW, Will RG, Ironside JW.

Clin Lab Med. 2003 Mar;23(1):87-108. Review.PMID: 12733426 [PubMed - indexed for MEDLINE]Related articles

The transmissible spongiform encephalopathies: pathogenic mechanisms and strategies for therapeutic intervention.

Head MW, Farquhar CF, Mabbott NA, Fraser JR.

Expert Opin Ther Targets. 2001 Oct;5(5):569-585.PMID: 12540284 [PubMed - as supplied by publisher]Related articles

Prion protein accumulation in eyes of patients with sporadic and variant Creutzfeldt-Jakob disease.

Head MW, Northcott V, Rennison K, Ritchie D, McCardle L, Bunn TJ, McLennan NF, Ironside JW, Tullo AB, Bonshek RE.

Invest Ophthalmol Vis Sci. 2003 Jan;44(1):342-6.PMID: 12506094 [PubMed - indexed for MEDLINE]Related articlesFree article