PubMed

Role of seminiferous tubular development in determining the FSH versus LH responsiveness to GnRH in early sexual maturation.

Pitteloud N, Thambundit A, Dwyer AA, Falardeau JL, Plummer L, Caronia LM, Hayes FJ, Lee H, Boepple PA, Crowley WF Jr.

Neuroendocrinology. 2009;90(3):260-8. Epub 2009 Oct 15.PMID: 19829004 [PubMed - in process]Related articles

Impaired fibroblast growth factor receptor 1 signaling as a cause of normosmic idiopathic hypogonadotropic hypogonadism.

Raivio T, Sidis Y, Plummer L, Chen H, Ma J, Mukherjee A, Jacobson-Dickman E, Quinton R, Van Vliet G, Lavoie H, Hughes VA, Dwyer A, Hayes FJ, Xu S, Sparks S, Kaiser UB, Mohammadi M, Pitteloud N.

J Clin Endocrinol Metab. 2009 Nov;94(11):4380-90. Epub 2009 Oct 9.PMID: 19820032 [PubMed - in process]Related articles

Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine.

Morrell MJ, Hayes FJ, Sluss PM, Adams JM, Bhatt M, Ozkara C, Warnock CR, Isojärvi J.

Ann Neurol. 2008 Aug;64(2):200-11.PMID: 18756476 [PubMed - indexed for MEDLINE]Related articles

Menstrual cycle dysfunction associated with neurologic and psychiatric disorders: their treatment in adolescents.

Joffe H, Hayes FJ.

Ann N Y Acad Sci. 2008;1135:219-29. Review.PMID: 18574228 [PubMed - indexed for MEDLINE]Related articles

Mutations in prokineticin 2 and prokineticin receptor 2 genes in human gonadotrophin-releasing hormone deficiency: molecular genetics and clinical spectrum.

Cole LW, Sidis Y, Zhang C, Quinton R, Plummer L, Pignatelli D, Hughes VA, Dwyer AA, Raivio T, Hayes FJ, Seminara SB, Huot C, Alos N, Speiser P, Takeshita A, Van Vliet G, Pearce S, Crowley WF Jr, Zhou QY, Pitteloud N.

J Clin Endocrinol Metab. 2008 Sep;93(9):3551-9. Epub 2008 Jun 17.PMID: 18559922 [PubMed - indexed for MEDLINE]Related articlesFree article

Inverse association of testosterone and the metabolic syndrome in men is consistent across race and ethnic groups.

Kupelian V, Hayes FJ, Link CL, Rosen R, McKinlay JB.

J Clin Endocrinol Metab. 2008 Sep;93(9):3403-10. Epub 2008 Jun 17.PMID: 18559915 [PubMed - indexed for MEDLINE]Related articlesFree article

The relative role of gonadal sex steroids and gonadotropin-releasing hormone pulse frequency in the regulation of follicle-stimulating hormone secretion in men.

Pitteloud N, Dwyer AA, DeCruz S, Lee H, Boepple PA, Crowley WF Jr, Hayes FJ.

J Clin Endocrinol Metab. 2008 Jul;93(7):2686-92. Epub 2008 Apr 29.PMID: 18445673 [PubMed - indexed for MEDLINE]Related articlesFree article

Relative roles of inhibin B and sex steroids in the negative feedback regulation of follicle-stimulating hormone in men across the full spectrum of seminiferous epithelium function.

Boepple PA, Hayes FJ, Dwyer AA, Raivio T, Lee H, Crowley WF Jr, Pitteloud N.

J Clin Endocrinol Metab. 2008 May;93(5):1809-14. Epub 2008 Feb 12.PMID: 18270253 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of luteinizing hormone secretion by testosterone in men requires aromatization for its pituitary but not its hypothalamic effects: evidence from the tandem study of normal and gonadotropin-releasing hormone-deficient men.

Pitteloud N, Dwyer AA, DeCruz S, Lee H, Boepple PA, Crowley WF Jr, Hayes FJ.

J Clin Endocrinol Metab. 2008 Mar;93(3):784-91. Epub 2007 Dec 11.PMID: 18073301 [PubMed - indexed for MEDLINE]Related articlesFree article

Mass spectrometric and physiological validation of a sensitive, automated, direct immunoassay for serum estradiol using the Architect.

Sluss PM, Hayes FJ, Adams JM, Barnes W, Williams G, Frost S, Ramp J, Pacenti D, Lehotay DC, George S, Ramsay C, Doss RC, Crowley WF Jr.

Clin Chim Acta. 2008 Feb;388(1-2):99-105. Epub 2007 Nov 26.PMID: 18023274 [PubMed - indexed for MEDLINE]Related articles

Reversal of idiopathic hypogonadotropic hypogonadism.

Raivio T, Falardeau J, Dwyer A, Quinton R, Hayes FJ, Hughes VA, Cole LW, Pearce SH, Lee H, Boepple P, Crowley WF Jr, Pitteloud N.

N Engl J Med. 2007 Aug 30;357(9):863-73.PMID: 17761590 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism.

Yialamas MA, Dwyer AA, Hanley E, Lee H, Pitteloud N, Hayes FJ.

J Clin Endocrinol Metab. 2007 Nov;92(11):4254-9. Epub 2007 Aug 28.PMID: 17726076 [PubMed - indexed for MEDLINE]Related articlesFree article

Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism.

Pitteloud N, Quinton R, Pearce S, Raivio T, Acierno J, Dwyer A, Plummer L, Hughes V, Seminara S, Cheng YZ, Li WP, Maccoll G, Eliseenkova AV, Olsen SK, Ibrahimi OA, Hayes FJ, Boepple P, Hall JE, Bouloux P, Mohammadi M, Crowley W.

J Clin Invest. 2007 Feb;117(2):457-63. Epub 2007 Jan 18.PMID: 17235395 [PubMed - indexed for MEDLINE]Related articlesFree article

Coding sequence analysis of GNRHR and GPR54 in patients with congenital and adult-onset forms of hypogonadotropic hypogonadism.

Cerrato F, Shagoury J, Kralickova M, Dwyer A, Falardeau J, Ozata M, Van Vliet G, Bouloux P, Hall JE, Hayes FJ, Pitteloud N, Martin KA, Welt C, Seminara SB.

Eur J Endocrinol. 2006 Nov;155 Suppl 1:S3-S10.PMID: 17074994 [PubMed - indexed for MEDLINE]Related articlesFree article

Testosterone therapy in adult men with androgen deficiency syndromes: an endocrine society clinical practice guideline.

Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, Swerdloff RS, Montori VM.

J Clin Endocrinol Metab. 2006 Jun;91(6):1995-2010. Epub 2006 May 23. Erratum in: J Clin Endocrinol Metab. 2006 Jul;91(7):2688. PMID: 16720669 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism.

Pitteloud N, Acierno JS Jr, Meysing A, Eliseenkova AV, Ma J, Ibrahimi OA, Metzger DL, Hayes FJ, Dwyer AA, Hughes VA, Yialamas M, Hall JE, Grant E, Mohammadi M, Crowley WF Jr.

Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6281-6. Epub 2006 Apr 10.PMID: 16606836 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men.

Pitteloud N, Mootha VK, Dwyer AA, Hardin M, Lee H, Eriksson KF, Tripathy D, Yialamas M, Groop L, Elahi D, Hayes FJ.

Diabetes Care. 2005 Jul;28(7):1636-42.PMID: 15983313 [PubMed - indexed for MEDLINE]Related articlesFree article

Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men.

Pitteloud N, Hardin M, Dwyer AA, Valassi E, Yialamas M, Elahi D, Hayes FJ.

J Clin Endocrinol Metab. 2005 May;90(5):2636-41. Epub 2005 Feb 15.PMID: 15713702 [PubMed - indexed for MEDLINE]Related articlesFree article

High-resolution reference ranges for estradiol, luteinizing hormone, and follicle-stimulating hormone in men and women using the AxSYM assay system.

Dighe AS, Moy JM, Hayes FJ, Sluss PM.

Clin Biochem. 2005 Feb;38(2):175-9.PMID: 15642281 [PubMed - indexed for MEDLINE]Related articles

Reversible kallmann syndrome, delayed puberty, and isolated anosmia occurring in a single family with a mutation in the fibroblast growth factor receptor 1 gene.

Pitteloud N, Acierno JS Jr, Meysing AU, Dwyer AA, Hayes FJ, Crowley WF Jr.

J Clin Endocrinol Metab. 2005 Mar;90(3):1317-22. Epub 2004 Dec 21.PMID: 15613419 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of inhibin A immunoassays: recommendation for adoption of standardized reporting.

Dighe AS, Hayes FJ, Khosravi J, Bodani U, Sluss PM.

Clin Chem. 2004 Apr;50(4):767-9. No abstract available. PMID: 15044338 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute stress masking the biochemical phenotype of partial androgen insensitivity syndrome in a patient with a novel mutation in the androgen receptor.

Pitteloud N, Villegas J, Dwyer AA, Crowley WF Jr, McPhaul MJ, Hayes FJ.

J Clin Endocrinol Metab. 2004 Mar;89(3):1053-8.PMID: 15001585 [PubMed - indexed for MEDLINE]Related articlesFree article

Androgens and the ageing male and female.

Yialamas MA, Hayes FJ.

Best Pract Res Clin Endocrinol Metab. 2003 Jun;17(2):223-36. Review.PMID: 12787549 [PubMed - indexed for MEDLINE]Related articles

Predictors of outcome of long-term GnRH therapy in men with idiopathic hypogonadotropic hypogonadism.

Pitteloud N, Hayes FJ, Dwyer A, Boepple PA, Lee H, Crowley WF Jr.

J Clin Endocrinol Metab. 2002 Sep;87(9):4128-36.PMID: 12213860 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of prior pubertal development, biochemical markers of testicular maturation, and genetics in elucidating the phenotypic heterogeneity of idiopathic hypogonadotropic hypogonadism.

Pitteloud N, Hayes FJ, Boepple PA, DeCruz S, Seminara SB, MacLaughlin DT, Crowley WF Jr.

J Clin Endocrinol Metab. 2002 Jan;87(1):152-60.PMID: 11788640 [PubMed - indexed for MEDLINE]Related articlesFree article

Importance of inhibin B in the regulation of FSH secretion in the human male.

Hayes FJ, Pitteloud N, DeCruz S, Crowley WF Jr, Boepple PA.

J Clin Endocrinol Metab. 2001 Nov;86(11):5541-6.PMID: 11701733 [PubMed - indexed for MEDLINE]Related articlesFree article

The fertile eunuch variant of idiopathic hypogonadotropic hypogonadism: spontaneous reversal associated with a homozygous mutation in the gonadotropin-releasing hormone receptor.

Pitteloud N, Boepple PA, DeCruz S, Valkenburgh SB, Crowley WF Jr, Hayes FJ.

J Clin Endocrinol Metab. 2001 Jun;86(6):2470-5.PMID: 11397842 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence, phenotypic spectrum, and modes of inheritance of gonadotropin-releasing hormone receptor mutations in idiopathic hypogonadotropic hypogonadism.

Beranova M, Oliveira LM, Bédécarrats GY, Schipani E, Vallejo M, Ammini AC, Quintos JB, Hall JE, Martin KA, Hayes FJ, Pitteloud N, Kaiser UB, Crowley WF Jr, Seminara SB.

J Clin Endocrinol Metab. 2001 Apr;86(4):1580-8.PMID: 11297587 [PubMed - indexed for MEDLINE]Related articlesFree article

The importance of autosomal genes in Kallmann syndrome: genotype-phenotype correlations and neuroendocrine characteristics.

Oliveira LM, Seminara SB, Beranova M, Hayes FJ, Valkenburgh SB, Schipani E, Costa EM, Latronico AC, Crowley WF Jr, Vallejo M.

J Clin Endocrinol Metab. 2001 Apr;86(4):1532-8.PMID: 11297579 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential regulation of gonadotropin secretion by testosterone in the human male: absence of a negative feedback effect of testosterone on follicle-stimulating hormone secretion.

Hayes FJ, DeCruz S, Seminara SB, Boepple PA, Crowley WF Jr.

J Clin Endocrinol Metab. 2001 Jan;86(1):53-8.PMID: 11231978 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetics of hypogonadotropic hypogonadism.

Seminara SB, Oliveira LM, Beranova M, Hayes FJ, Crowley WF Jr.

J Endocrinol Invest. 2000 Oct;23(9):560-5. Review.PMID: 11079449 [PubMed - indexed for MEDLINE]Related articles

Aromatase inhibition in the human male reveals a hypothalamic site of estrogen feedback.

Hayes FJ, Seminara SB, Decruz S, Boepple PA, Crowley WF Jr.

J Clin Endocrinol Metab. 2000 Sep;85(9):3027-35.PMID: 10999781 [PubMed - indexed for MEDLINE]Related articlesFree article

Testosterone--fountain of youth or drug of abuse?

Hayes FJ.

J Clin Endocrinol Metab. 2000 Sep;85(9):3020-3. No abstract available. PMID: 10999779 [PubMed - indexed for MEDLINE]Related articlesFree article

Gender difference in the response of growth hormone (GH)-deficient adults to GH therapy.

Hayes FJ, Fiad TM, McKenna TJ.

Metabolism. 1999 Mar;48(3):308-13.PMID: 10094105 [PubMed - indexed for MEDLINE]Related articles

Free alpha-subunit is superior to luteinizing hormone as a marker of gonadotropin-releasing hormone despite desensitization at fast pulse frequencies.

Hayes FJ, McNicholl DJ, Schoenfeld D, Marsh EE, Hall JE.

J Clin Endocrinol Metab. 1999 Mar;84(3):1028-36.PMID: 10084591 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypogonadotropic hypogonadism.

Hayes FJ, Seminara SB, Crowley WF Jr.

Endocrinol Metab Clin North Am. 1998 Dec;27(4):739-63, vii. Review.PMID: 9922906 [PubMed - indexed for MEDLINE]Related articles

Insights into hypothalamic-pituitary dysfunction in polycystic ovary syndrome.

Hall JE, Taylor AE, Hayes FJ, Crowley WF Jr.

J Endocrinol Invest. 1998 Oct;21(9):602-11. Review.PMID: 9856414 [PubMed - indexed for MEDLINE]Related articles

Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): pathophysiological and genetic considerations.

Seminara SB, Hayes FJ, Crowley WF Jr.

Endocr Rev. 1998 Oct;19(5):521-39. Review. No abstract available. PMID: 9793755 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of a gonadotropin-releasing hormone antagonist as a physiologic probe in polycystic ovary syndrome: assessment of neuroendocrine and androgen dynamics.

Hayes FJ, Taylor AE, Martin KA, Hall JE.

J Clin Endocrinol Metab. 1998 Jul;83(7):2343-9.PMID: 9661606 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical review 96: Differential control of gonadotropin secretion in the human: endocrine role of inhibin.

Hayes FJ, Hall JE, Boepple PA, Crowley WF Jr.

J Clin Endocrinol Metab. 1998 Jun;83(6):1835-41. Review.PMID: 9626105 [PubMed - indexed for MEDLINE]Related articlesFree article

Gonadotropin pulsations across development.

Hayes FJ, Crowley WF Jr.

Horm Res. 1998;49(3-4):163-8. Review.PMID: 9550119 [PubMed - indexed for MEDLINE]Related articles

Virilization in a postmenopausal woman as a result of hilus cell hyperplasia associated with a simple ovarian cyst.

Hayes FJ, Sheahan K, Rajendiran S, McKenna TJ.

Am J Obstet Gynecol. 1997 Mar;176(3):719-20.PMID: 9077639 [PubMed - indexed for MEDLINE]Related articles

Effects of nifedipine treatment on the renin-angiotensin-aldosterone axis.

Fiad TM, Cunningham SK, Hayes FJ, McKenna TJ.

J Clin Endocrinol Metab. 1997 Feb;82(2):457-60.PMID: 9024236 [PubMed - indexed for MEDLINE]Related articlesFree article

Activity of the renin-angiotensin-aldosterone axis is dependent on the occurrence of edema in growth hormone (GH)-deficient adults treated with GH.

Hayes FJ, Fiad TM, McKenna TJ.

J Clin Endocrinol Metab. 1997 Jan;82(1):322-3. No abstract available. PMID: 8989283 [PubMed - indexed for MEDLINE]Related articles

The occurrence of lymphocytic hypophysitis in a first but not subsequent pregnancy.

Hayes FJ, McKenna TJ.

J Clin Endocrinol Metab. 1996 Aug;81(8):3131-2. No abstract available. PMID: 8768889 [PubMed - indexed for MEDLINE]Related articles

Aggressive thyroid cancer associated with toxic nodular goitre.

Hayes FJ, Sheahan K, Heffernan A, McKenna TJ.

Eur J Endocrinol. 1996 Mar;134(3):366-70.PMID: 8616537 [PubMed - indexed for MEDLINE]Related articles

Diabetes mellitus in an adult cystic fibrosis population.

Hayes FJ, O'Brien A, O'Brien C, Fitzgerald MX, McKenna MJ.

Ir Med J. 1995 May-Jun;88(3):102-4.PMID: 7635678 [PubMed - indexed for MEDLINE]Related articles

Rapid liquid chromatographic-mass spectrometric assay for oxymetazoline in whole rat blood.

Hayes FJ, Baker TR, Dobson RL, Tsueda MS.

J Chromatogr A. 1995 Feb 10;692(1-2):73-81.PMID: 7719462 [PubMed - indexed for MEDLINE]Related articles

Thoracic polyradiculopathy--abdominal wall swelling and sensory symptoms in diabetes mellitus.

Hayes FJ, Redmond JM, McKenna MJ.

Ir Med J. 1994 Sep-Oct;87(5):150-1.PMID: 7960657 [PubMed - indexed for MEDLINE]Related articles

Simultaneous immunoassay using electrochemical detection of metal ion labels.

Hayes FJ, Halsall HB, Heineman WR.

Anal Chem. 1994 Jun 1;66(11):1860-5.PMID: 8030790 [PubMed - indexed for MEDLINE]Related articles