PubMed

Cardiac transplantation should be considered in selected patients with either AL or hereditary forms of amyloidosis: the UK National Amyloidosis Centre experience.

Gibbs SD, Sattianayagam PT, Hawkins PN, Gillmore JD.

Intern Med J. 2009 Nov;39(11):786-7; author reply 787-8. No abstract available. PMID: 19912412 [PubMed - in process]Related articles

Systemic amyloidosis and the gastrointestinal tract.

Sattianayagam PT, Hawkins PN, Gillmore JD.

Nat Rev Gastroenterol Hepatol. 2009 Oct;6(10):608-17. Epub 2009 Sep 1.PMID: 19724253 [PubMed - in process]Related articles

Outcomes of heart transplantation for cardiac amyloidosis: subanalysis of the Spanish registry for heart transplantation.

Sattianayagam PT, Gibbs SD, Wechalekar AD, Lachmann HJ, Hawkins PN, Gillmore JD.

Am J Transplant. 2009 Oct;9(10):2443. Epub 2009 Aug 14. No abstract available. PMID: 19681817 [PubMed - in process]Related articles

Use of canakinumab in the cryopyrin-associated periodic syndrome.

Lachmann HJ, Kone-Paut I, Kuemmerle-Deschner JB, Leslie KS, Hachulla E, Quartier P, Gitton X, Widmer A, Patel N, Hawkins PN; Canakinumab in CAPS Study Group.

N Engl J Med. 2009 Jun 4;360(23):2416-25.PMID: 19494217 [PubMed - indexed for MEDLINE]Related articles

Molecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P component.

Kolstoe SE, Ridha BH, Bellotti V, Wang N, Robinson CV, Crutch SJ, Keir G, Kukkastenvehmas R, Gallimore JR, Hutchinson WL, Hawkins PN, Wood SP, Rossor MN, Pepys MB.

Proc Natl Acad Sci U S A. 2009 May 5;106(18):7619-23. Epub 2009 Apr 16.PMID: 19372378 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes.

Lachmann HJ, Lowe P, Felix SD, Rordorf C, Leslie K, Madhoo S, Wittkowski H, Bek S, Hartmann N, Bosset S, Hawkins PN, Jung T.

J Exp Med. 2009 May 11;206(5):1029-36. Epub 2009 Apr 13.PMID: 19364880 [PubMed - indexed for MEDLINE]Related articlesFree article

Laryngeal presentation of systemic apolipoprotein A-I-derived amyloidosis.

Hazenberg AJ, Dikkers FG, Hawkins PN, Bijzet J, Rowczenio D, Gilbertson J, Posthumus MD, Leijsma MK, Hazenberg BP.

Laryngoscope. 2009 Mar;119(3):608-15.PMID: 19235761 [PubMed - indexed for MEDLINE]Related articles

Developments in the scientific and clinical understanding of autoinflammatory disorders.

Lachmann HJ, Hawkins PN.

Arthritis Res Ther. 2009;11(1):212. Epub 2009 Jan 30.PMID: 19232070 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac amyloidosis, a monoclonal gammopathy and a potentially misleading mutation.

Wechalekar AD, Offer M, Gillmore JD, Hawkins PN, Lachmann HJ.

Nat Clin Pract Cardiovasc Med. 2009 Feb;6(2):128-33. Epub 2008 Dec 17.PMID: 19079367 [PubMed - indexed for MEDLINE]Related articles

Diagnosis, pathogenesis, treatment, and prognosis of hereditary fibrinogen A alpha-chain amyloidosis.

Gillmore JD, Lachmann HJ, Rowczenio D, Gilbertson JA, Zeng CH, Liu ZH, Li LS, Wechalekar A, Hawkins PN.

J Am Soc Nephrol. 2009 Feb;20(2):444-51. Epub 2008 Dec 10.PMID: 19073821 [PubMed - indexed for MEDLINE]Related articles

Cardiovascular magnetic resonance and prognosis in cardiac amyloidosis.

Maceira AM, Prasad SK, Hawkins PN, Roughton M, Pennell DJ.

J Cardiovasc Magn Reson. 2008 Nov 25;10(1):54.PMID: 19032744 [PubMed - indexed for MEDLINE]Related articlesFree article

AL amyloidosis associated with IgM paraproteinemia: clinical profile and treatment outcome.

Wechalekar AD, Lachmann HJ, Goodman HJ, Bradwell A, Hawkins PN, Gillmore JD.

Blood. 2008 Nov 15;112(10):4009-16. Epub 2008 Aug 15.PMID: 18708629 [PubMed - indexed for MEDLINE]Related articlesFree article

Heart transplantation for homozygous familial transthyretin (TTR) V122I cardiac amyloidosis.

Hamour IM, Lachmann HJ, Goodman HJ, Petrou M, Burke MM, Hawkins PN, Banner NR.

Am J Transplant. 2008 May;8(5):1056-9. Epub 2008 Mar 2.PMID: 18318779 [PubMed - indexed for MEDLINE]Related articles

Use of anakinra (Kineret) in the treatment of familial cold autoinflammatory syndrome with a 16-month follow-up.

Ross JB, Finlayson LA, Klotz PJ, Langley RG, Gaudet R, Thompson K, Churchman SM, McDermott MF, Hawkins PN.

J Cutan Med Surg. 2008 Jan-Feb;12(1):8-16.PMID: 18258152 [PubMed - indexed for MEDLINE]Related articles

Efficacy of bortezomib in systemic AL amyloidosis with relapsed/refractory clonal disease.

Wechalekar AD, Lachmann HJ, Offer M, Hawkins PN, Gillmore JD.

Haematologica. 2008 Feb;93(2):295-8.PMID: 18245653 [PubMed - indexed for MEDLINE]Related articlesFree article

Abnormal tumor necrosis factor receptor I cell surface expression and NF-kappaB activation in tumor necrosis factor receptor-associated periodic syndrome.

Nedjai B, Hitman GA, Yousaf N, Chernajovsky Y, Stjernberg-Salmela S, Pettersson T, Ranki A, Hawkins PN, Arkwright PD, McDermott MF, Turner MD.

Arthritis Rheum. 2008 Jan;58(1):273-83.PMID: 18163488 [PubMed - indexed for MEDLINE]Related articlesFree article

Perspectives in treatment of AL amyloidosis.

Wechalekar AD, Hawkins PN, Gillmore JD.

Br J Haematol. 2008 Feb;140(4):365-77. Epub 2007 Dec 19. Review.PMID: 18162121 [PubMed - indexed for MEDLINE]Related articles

Characterisation and management of vitreous and nerve amyloid in familial amyloid polyneuropathy due to variant transthyretin, Phe33Val.

Gregory ME, Carey M, Hawkins PN, Banerjee S, Gillmore JD.

Br J Ophthalmol. 2008 Jan;92(1):34-5, 142. No abstract available. PMID: 18156374 [PubMed - indexed for MEDLINE]Related articles

Evaluation and management of the cardiac amyloidosis.

Selvanayagam JB, Hawkins PN, Paul B, Myerson SG, Neubauer S.

J Am Coll Cardiol. 2007 Nov 27;50(22):2101-10. Epub 2007 Nov 13. Review.PMID: 18036445 [PubMed - indexed for MEDLINE]Related articles

Disease-associated prion protein is not detectable in human systemic amyloid deposits.

Tennent GA, Head MW, Bishop M, Hawkins PN, Will RG, Knight R, Peden AH, McCardle LM, Ironside JW, Pepys MB.

J Pathol. 2007 Dec;213(4):376-83.PMID: 17955450 [PubMed - indexed for MEDLINE]Related articles

Hereditary amyloidosis with progressive peripheral neuropathy associated with apolipoprotein AI Gly26Arg: outcome of hepatorenal transplantation.

Testro AG, Brennan SO, Macdonell RA, Hawkins PN, Angus PW.

Liver Transpl. 2007 Jul;13(7):1028-31.PMID: 17600344 [PubMed - indexed for MEDLINE]Related articlesFree article

Diagnostic performance of amyloid A protein quantification in fat tissue of patients with clinical AA amyloidosis.

Hazenberg BP, Bijzet J, Limburg PC, Skinner M, Hawkins PN, Butrimiene I, Livneh A, Lesnyak O, Nasonov EL, Filipowicz-Sosnowska A, Gül A, Merlini G, Wiland P, Ozdogan H, Gorevic PD, Maïz HB, Benson MD, Direskeneli H, Kaarela K, Garceau D, Hauck W, Van Rijswijk MH.

Amyloid. 2007 Jun;14(2):133-40. Erratum in: Amyloid. 2007 Dec;14(4):325. PMID: 17577686 [PubMed - indexed for MEDLINE]Related articles

Natural history and outcome in systemic AA amyloidosis.

Lachmann HJ, Goodman HJ, Gilbertson JA, Gallimore JR, Sabin CA, Gillmore JD, Hawkins PN.

N Engl J Med. 2007 Jun 7;356(23):2361-71.PMID: 17554117 [PubMed - indexed for MEDLINE]Related articlesFree article

Eprodisate for the treatment of renal disease in AA amyloidosis.

Dember LM, Hawkins PN, Hazenberg BP, Gorevic PD, Merlini G, Butrimiene I, Livneh A, Lesnyak O, Puéchal X, Lachmann HJ, Obici L, Balshaw R, Garceau D, Hauck W, Skinner M; Eprodisate for AA Amyloidosis Trial Group.

N Engl J Med. 2007 Jun 7;356(23):2349-60.PMID: 17554116 [PubMed - indexed for MEDLINE]Related articlesFree article

Bone marrow findings correlate with clinical outcome in systemic AL amyloidosis patients.

Hasserjian RP, Goodman HJ, Lachmann HJ, Muzikansky A, Hawkins PN.

Histopathology. 2007 Apr;50(5):567-73.PMID: 17394492 [PubMed - indexed for MEDLINE]Related articles

Amyloidosis and the lung.

Lachmann HJ, Hawkins PN.

Chron Respir Dis. 2006;3(4):203-14. Review.PMID: 17190124 [PubMed - indexed for MEDLINE]Related articles

Phenotype, genotype, and sustained response to anakinra in 22 patients with autoinflammatory disease associated with CIAS-1/NALP3 mutations.

Leslie KS, Lachmann HJ, Bruning E, McGrath JA, Bybee A, Gallimore JR, Roberts PF, Woo P, Grattan CE, Hawkins PN.

Arch Dermatol. 2006 Dec;142(12):1591-7.PMID: 17178985 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute renal failure and nephrotic range proteinuria due to amyloidosis in an HIV-infected patient.

Chan-Tack KM, Ahuja N, Weinman EJ, Wali RK, Uche A, Greisman LA, Drachenberg C, Hawkins PN, Redfield RR.

Am J Med Sci. 2006 Dec;332(6):364-7.PMID: 17170630 [PubMed - indexed for MEDLINE]Related articles

Images in cardiovascular medicine. Intermittent loss of second heart sound.

Joshi J, Wechalekar AD, Bourdillon PJ, Joshi RP, Rahemtulla A, Hawkins PN.

Circulation. 2006 Nov 28;114(22):e612-3. No abstract available. PMID: 17130350 [PubMed - indexed for MEDLINE]Related articlesFree article

Human plasma fibrinogen is synthesized in the liver.

Tennent GA, Brennan SO, Stangou AJ, O'Grady J, Hawkins PN, Pepys MB.

Blood. 2007 Mar 1;109(5):1971-4. Epub 2006 Nov 2.PMID: 17082318 [PubMed - indexed for MEDLINE]Related articlesFree article

Safety and efficacy of risk-adapted cyclophosphamide, thalidomide, and dexamethasone in systemic AL amyloidosis.

Wechalekar AD, Goodman HJ, Lachmann HJ, Offer M, Hawkins PN, Gillmore JD.

Blood. 2007 Jan 15;109(2):457-64. Epub 2006 Sep 21.PMID: 16990593 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel amyloidogenic transthyretin variant, Gly53Ala, associated with intermittent headaches and ataxia.

Douglass C, Suvarna K, Reilly MM, Hawkins PN, Hadjivassiliou M.

J Neurol Neurosurg Psychiatry. 2007 Feb;78(2):193-5. Epub 2006 Sep 13.PMID: 16971399 [PubMed - indexed for MEDLINE]Related articles

Renal amyloidosis in intravenous drug users.

Connolly JO, Gillmore JD, Lachmann HJ, Davenport A, Hawkins PN, Woolfson RG.

QJM. 2006 Nov;99(11):737-42. Epub 2006 Sep 6.PMID: 16956922 [PubMed - indexed for MEDLINE]Related articlesFree article

Drug Insight: emerging therapies for amyloidosis.

Gillmore JD, Hawkins PN.

Nat Clin Pract Nephrol. 2006 May;2(5):263-70. Review.PMID: 16932439 [PubMed - indexed for MEDLINE]Related articles

Organ transplantation in hereditary apolipoprotein AI amyloidosis.

Gillmore JD, Stangou AJ, Lachmann HJ, Goodman HJ, Wechalekar AD, Acheson J, Tennent GA, Bybee A, Gilbertson J, Rowczenio D, O'Grady J, Heaton ND, Pepys MB, Hawkins PN.

Am J Transplant. 2006 Oct;6(10):2342-7. Epub 2006 Aug 21.PMID: 16925563 [PubMed - indexed for MEDLINE]Related articles

Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition.

Goldbach-Mansky R, Dailey NJ, Canna SW, Gelabert A, Jones J, Rubin BI, Kim HJ, Brewer C, Zalewski C, Wiggs E, Hill S, Turner ML, Karp BI, Aksentijevich I, Pucino F, Penzak SR, Haverkamp MH, Stein L, Adams BS, Moore TL, Fuhlbrigge RC, Shaham B, Jarvis JN, O'Neil K, Vehe RK, Beitz LO, Gardner G, Hannan WP, Warren RW, Horn W, Cole JL, Paul SM, Hawkins PN, Pham TH, Snyder C, Wesley RA, Hoffmann SC, Holland SM, Butman JA, Kastner DL.

N Engl J Med. 2006 Aug 10;355(6):581-92.PMID: 16899778 [PubMed - indexed for MEDLINE]Related articlesFree article

Amyloidosis and primary biliary cirrhosis, Rodriguez-Luna et al.

Goodman HJ, Hawkins PN.

Dig Dis Sci. 2006 Jun;51(6):1133. No abstract available. PMID: 16865582 [PubMed - indexed for MEDLINE]Related articles

Outcome of autologous stem cell transplantation for AL amyloidosis in the UK.

Goodman HJ, Gillmore JD, Lachmann HJ, Wechalekar AD, Bradwell AR, Hawkins PN.

Br J Haematol. 2006 Aug;134(4):417-25. Epub 2006 Jul 5.PMID: 16822290 [PubMed - indexed for MEDLINE]Related articles

Hereditary auto-inflammatory disorders and biologics.

Church LD, Churchman SM, Hawkins PN, McDermott MF.

Springer Semin Immunopathol. 2006 Jun;27(4):494-508. Epub 2006 May 4. Review.PMID: 16738958 [PubMed - indexed for MEDLINE]Related articles

AA amyloidosis complicating hyperimmunoglobulinemia D with periodic fever syndrome: a report of two cases.

Lachmann HJ, Goodman HJ, Andrews PA, Gallagher H, Marsh J, Breuer S, Rowczenio DM, Bybee A, Hawkins PN.

Arthritis Rheum. 2006 Jun;54(6):2010-4.PMID: 16732551 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeting C-reactive protein for the treatment of cardiovascular disease.

Pepys MB, Hirschfield GM, Tennent GA, Gallimore JR, Kahan MC, Bellotti V, Hawkins PN, Myers RM, Smith MD, Polara A, Cobb AJ, Ley SV, Aquilina JA, Robinson CV, Sharif I, Gray GA, Sabin CA, Jenvey MC, Kolstoe SE, Thompson D, Wood SP.

Nature. 2006 Apr 27;440(7088):1217-21.PMID: 16642000 [PubMed - indexed for MEDLINE]Related articles

Long-term outcome of high-dose melphalan and autologous stem cell transplantation for AL amyloidosis.

Perz JB, Rahemtulla A, Giles C, Szydlo RM, Davis J, Gopaul D, Gillmore J, Mathias CJ, Hawkins PN, Apperley JF.

Bone Marrow Transplant. 2006 May;37(10):937-43.PMID: 16565738 [PubMed - indexed for MEDLINE]Related articles

Diagnostic performance of 123I-labeled serum amyloid P component scintigraphy in patients with amyloidosis.

Hazenberg BP, van Rijswijk MH, Piers DA, Lub-de Hooge MN, Vellenga E, Haagsma EB, Hawkins PN, Jager PL.

Am J Med. 2006 Apr;119(4):355.e15-24.PMID: 16564782 [PubMed - indexed for MEDLINE]Related articles

Systemic amyloidosis.

Lachmann HJ, Hawkins PN.

Curr Opin Pharmacol. 2006 Apr;6(2):214-20. Epub 2006 Feb 17. Review.PMID: 16483845 [PubMed - indexed for MEDLINE]Related articles

Clinical and subclinical inflammation in patients with familial Mediterranean fever and in heterozygous carriers of MEFV mutations.

Lachmann HJ, Sengül B, Yavuzşen TU, Booth DR, Booth SE, Bybee A, Gallimore JR, Soytürk M, Akar S, Tunca M, Hawkins PN.

Rheumatology (Oxford). 2006 Jun;45(6):746-50. Epub 2006 Jan 10.PMID: 16403826 [PubMed - indexed for MEDLINE]Related articlesFree article

Proinflammatory effects of bacterial recombinant human C-reactive protein are caused by contamination with bacterial products, not by C-reactive protein itself.

Pepys MB, Hawkins PN, Kahan MC, Tennent GA, Gallimore JR, Graham D, Sabin CA, Zychlinsky A, de Diego J.

Circ Res. 2005 Nov 25;97(11):e97-103. Epub 2005 Oct 27.PMID: 16254214 [PubMed - indexed for MEDLINE]Related articlesFree article

Hereditary amyloidosis in early childhood associated with a novel insertion-deletion (indel) in the fibrinogen Aalpha chain gene.

Kang HG, Bybee A, Ha IS, Park MS, Gilbertson JA, Cheong HI, Choi Y, Hawkins PN.

Kidney Int. 2005 Nov;68(5):1994-8.PMID: 16221199 [PubMed - indexed for MEDLINE]Related articles

Sequential heart and autologous stem cell transplantation for systemic AL amyloidosis.

Gillmore JD, Goodman HJ, Lachmann HJ, Offer M, Wechalekar AD, Joshi J, Pepys MB, Hawkins PN.

Blood. 2006 Feb 1;107(3):1227-9. Epub 2005 Oct 6.PMID: 16210334 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative high-resolution microradiographic imaging of amyloid deposits in a novel murine model of AA amyloidosis.

Wall JS, Kennel SJ, Paulus MJ, Gleason S, Gregor J, Baba J, Schell M, Richey T, O'Nuallain B, Donnell R, Hawkins PN, Weiss DT, Solomon A.

Amyloid. 2005 Sep;12(3):149-56.PMID: 16194869 [PubMed - indexed for MEDLINE]Related articles

Colchicine responsive periodic fever syndrome associated with pyrin I591T.

Fisher BA, Lachmann HJ, Rowczenio D, Goodman HJ, Bhalara S, Hawkins PN.

Ann Rheum Dis. 2005 Sep;64(9):1384-5. No abstract available. PMID: 16100353 [PubMed - indexed for MEDLINE]Related articlesFree article