PubMed

Hypothalamic leptin signaling regulates hepatic insulin sensitivity via a neurocircuit involving the vagus nerve.

German J, Kim F, Schwartz GJ, Havel PJ, Rhodes CJ, Schwartz MW, Morton GJ.

Endocrinology. 2009 Oct;150(10):4502-11. Epub 2009 Jul 2.PMID: 19574396 [PubMed - indexed for MEDLINE]Related articles

Maternal influence of prolyl endopeptidase on fat mass of adult progeny.

Warden CH, Fisler JS, Espinal G, Graham J, Havel PJ, Perroud B.

Int J Obes (Lond). 2009 Sep;33(9):1013-22. Epub 2009 Jun 30.PMID: 19564876 [PubMed - in process]Related articles

Effects of weight loss, induced by gastric bypass surgery, on HDL remodeling in obese women.

Asztalos BF, Swarbrick MM, Schaefer EJ, Dallal GE, Horvath KV, Ai M, Stanhope KL, Austrheim-Smith I, Wolfe BM, Ali M, Havel PJ.

J Lipid Res. 2009 May 14. [Epub ahead of print]PMID: 19443861 [PubMed - as supplied by publisher]Related articlesFree article

Fructose consumption: considerations for future research on its effects on adipose distribution, lipid metabolism, and insulin sensitivity in humans.

Stanhope KL, Havel PJ.

J Nutr. 2009 Jun;139(6):1236S-1241S. Epub 2009 Apr 29.PMID: 19403712 [PubMed - indexed for MEDLINE]Related articles

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans.

Stanhope KL, Schwarz JM, Keim NL, Griffen SC, Bremer AA, Graham JL, Hatcher B, Cox CL, Dyachenko A, Zhang W, McGahan JP, Seibert A, Krauss RM, Chiu S, Schaefer EJ, Ai M, Otokozawa S, Nakajima K, Nakano T, Beysen C, Hellerstein MK, Berglund L, Havel PJ.

J Clin Invest. 2009 May;119(5):1322-34. doi: 10.1172/JCI37385. Epub 2009 Apr 20.PMID: 19381015 [PubMed - indexed for MEDLINE]Related articlesFree article

The correlation between TG vs remnant lipoproteins in the fasting and postprandial plasma of 23 volunteers.

Nakajima K, Nakano T, Moon HD, Nagamine T, Stanhope KL, Havel PJ, Warnick GR.

Clin Chim Acta. 2009 Jun 27;404(2):124-7. Epub 2009 Apr 1.PMID: 19345200 [PubMed - indexed for MEDLINE]Related articles

Endocrine and metabolic effects of consuming fructose- and glucose-sweetened beverages with meals in obese men and women: influence of insulin resistance on plasma triglyceride responses.

Teff KL, Grudziak J, Townsend RR, Dunn TN, Grant RW, Adams SH, Keim NL, Cummings BP, Stanhope KL, Havel PJ.

J Clin Endocrinol Metab. 2009 May;94(5):1562-9. Epub 2009 Feb 10.PMID: 19208729 [PubMed - indexed for MEDLINE]Related articles

Inhibition of protein tyrosine phosphatase-1B with antisense oligonucleotides improves insulin sensitivity and increases adiponectin concentrations in monkeys.

Swarbrick MM, Havel PJ, Levin AA, Bremer AA, Stanhope KL, Butler M, Booten SL, Graham JL, McKay RA, Murray SF, Watts LM, Monia BP, Bhanot S.

Endocrinology. 2009 Apr;150(4):1670-9. Epub 2009 Jan 22.PMID: 19164474 [PubMed - indexed for MEDLINE]Related articles

Association of adiponectin with mortality in older adults: the Health, Aging, and Body Composition Study.

Poehls J, Wassel CL, Harris TB, Havel PJ, Swarbrick MM, Cummings SR, Newman AB, Satterfield S, Kanaya AM; Health ABC Study.

Diabetologia. 2009 Apr;52(4):591-5. Epub 2009 Jan 22.PMID: 19159917 [PubMed - indexed for MEDLINE]Related articlesFree article

Endocrine and metabolic effects of consuming beverages sweetened with fructose, glucose, sucrose, or high-fructose corn syrup.

Stanhope KL, Havel PJ.

Am J Clin Nutr. 2008 Dec;88(6):1733S-1737S. Review.PMID: 19064538 [PubMed - indexed for MEDLINE]Related articles

Relationships between plasma adiponectin and body fat distribution, insulin sensitivity, and plasma lipoproteins in Alaskan Yup'ik Eskimos: the Center for Alaska Native Health Research study.

Goropashnaya AV, Herron J, Sexton M, Havel PJ, Stanhope KL, Plaetke R, Mohatt GV, Boyer BB.

Metabolism. 2009 Jan;58(1):22-9.PMID: 19059527 [PubMed - indexed for MEDLINE]Related articles

Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat.

Cummings BP, Digitale EK, Stanhope KL, Graham JL, Baskin DG, Reed BJ, Sweet IR, Griffen SC, Havel PJ.

Am J Physiol Regul Integr Comp Physiol. 2008 Dec;295(6):R1782-93. Epub 2008 Oct 1.PMID: 18832086 [PubMed - indexed for MEDLINE]Related articles

Calcium supplementation does not alter lipid oxidation or lipolysis in overweight/obese women.

Sampath V, Havel PJ, King JC.

Obesity (Silver Spring). 2008 Nov;16(11):2400-4. Epub 2008 Aug 14.PMID: 18719672 [PubMed - indexed for MEDLINE]Related articles

Longitudinal changes in pancreatic and adipocyte hormones following Roux-en-Y gastric bypass surgery.

Swarbrick MM, Stanhope KL, Austrheim-Smith IT, Van Loan MD, Ali MR, Wolfe BM, Havel PJ.

Diabetologia. 2008 Oct;51(10):1901-11. Epub 2008 Aug 15.PMID: 18704364 [PubMed - indexed for MEDLINE]Related articles

Physiological, pharmacological, and nutritional regulation of circulating adiponectin concentrations in humans.

Swarbrick MM, Havel PJ.

Metab Syndr Relat Disord. 2008 Summer;6(2):87-102. Review.PMID: 18510434 [PubMed - indexed for MEDLINE]Related articles

Twenty-four-hour endocrine and metabolic profiles following consumption of high-fructose corn syrup-, sucrose-, fructose-, and glucose-sweetened beverages with meals.

Stanhope KL, Griffen SC, Bair BR, Swarbrick MM, Keim NL, Havel PJ.

Am J Clin Nutr. 2008 May;87(5):1194-203.PMID: 18469239 [PubMed - indexed for MEDLINE]Related articlesFree article

CRP and adiponectin and its oligomers in the metabolic syndrome: evaluation of new laboratory-based biomarkers.

Devaraj S, Swarbrick MM, Singh U, Adams-Huet B, Havel PJ, Jialal I.

Am J Clin Pathol. 2008 May;129(5):815-22.PMID: 18426744 [PubMed - indexed for MEDLINE]Related articlesFree article

Correlation of circulating full-length visfatin (PBEF/NAMPT) with metabolic parameters in subjects with and without diabetes: a cross-sectional study.

Retnakaran R, Youn BS, Liu Y, Hanley AJ, Lee NS, Park JW, Song ES, Vu V, Kim W, Tungtrongchitr R, Havel PJ, Swarbrick MM, Shaw C, Sweeney G.

Clin Endocrinol (Oxf). 2008 Dec;69(6):885-93. Epub 2008 Apr 10.PMID: 18410550 [PubMed - indexed for MEDLINE]Related articles

Consumption of fructose-sweetened beverages for 10 weeks increases postprandial triacylglycerol and apolipoprotein-B concentrations in overweight and obese women.

Swarbrick MM, Stanhope KL, Elliott SS, Graham JL, Krauss RM, Christiansen MP, Griffen SC, Keim NL, Havel PJ.

Br J Nutr. 2008 Nov;100(5):947-52.PMID: 18384705 [PubMed - indexed for MEDLINE]Related articles

Metabolic and endocrine profiles in response to systemic infusion of fructose and glucose in rhesus macaques.

Adams SH, Stanhope KL, Grant RW, Cummings BP, Havel PJ.

Endocrinology. 2008 Jun;149(6):3002-8. Epub 2008 Feb 28.PMID: 18308841 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of dietary n-3 polyunsaturated fatty acids on plasma total and high-molecular-weight adiponectin concentrations in overweight to moderately obese men and women.

Kratz M, Swarbrick MM, Callahan HS, Matthys CC, Havel PJ, Weigle DS.

Am J Clin Nutr. 2008 Feb;87(2):347-53.PMID: 18258624 [PubMed - indexed for MEDLINE]Related articlesFree article

Fructose consumption: potential mechanisms for its effects to increase visceral adiposity and induce dyslipidemia and insulin resistance.

Stanhope KL, Havel PJ.

Curr Opin Lipidol. 2008 Feb;19(1):16-24. Review.PMID: 18196982 [PubMed - indexed for MEDLINE]Related articles

Metabolic syndrome in Yup'ik Eskimos: the Center for Alaska Native Health Research (CANHR) Study.

Boyer BB, Mohatt GV, Plaetke R, Herron J, Stanhope KL, Stephensen C, Havel PJ; CANHR Project Team.

Obesity (Silver Spring). 2007 Nov;15(11):2535-40.PMID: 18070741 [PubMed - indexed for MEDLINE]Related articles

Synergistic impairment of glucose homeostasis in ob/ob mice lacking functional serotonin 2C receptors.

Wade JM, Juneja P, MacKay AW, Graham J, Havel PJ, Tecott LH, Goulding EH.

Endocrinology. 2008 Mar;149(3):955-61. Epub 2007 Nov 26.PMID: 18039786 [PubMed - indexed for MEDLINE]Related articlesFree article

Analytical validation and biological evaluation of a high molecular-weight adiponectin ELISA.

Sinha MK, Songer T, Xiao Q, Sloan JH, Wang J, Ji S, Alborn WE, Davis RA, Swarbrick MM, Stanhope KL, Wolfe BM, Havel PJ, Schraw T, Konrad RJ, Scherer PE, Mistry JS.

Clin Chem. 2007 Dec;53(12):2144-51. Epub 2007 Oct 19.PMID: 17951289 [PubMed - indexed for MEDLINE]Related articlesFree article

Longitudinal measures of circulating leptin and ghrelin concentrations are associated with the growth of young Peruvian children but are not affected by zinc supplementation.

Arsenault JE, Havel PJ, López de Romaña D, Penny ME, Van Loan MD, Brown KH.

Am J Clin Nutr. 2007 Oct;86(4):1111-9.PMID: 17921390 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic syndrome in adolescents with spinal cord dysfunction.

Nelson MD, Widman LM, Abresch RT, Stanhope K, Havel PJ, Styne DM, McDonald CM.

J Spinal Cord Med. 2007;30 Suppl 1:S127-39.PMID: 17874698 [PubMed - indexed for MEDLINE]Related articlesFree article

Fructose consumption and moderate zinc deficiency influence growth and adipocyte metabolism in young rats prone to adult-onset obesity.

Streiff EL, Stanhope KL, Graham J, Havel PJ, King JC.

Biol Trace Elem Res. 2007 Jul;118(1):53-64.PMID: 17848731 [PubMed - indexed for MEDLINE]Related articles

Adiponectin levels are associated with coronary artery disease across Caucasian and African-American ethnicity.

Lu G, Chiem A, Anuurad E, Havel PJ, Pearson TA, Ormsby B, Berglund L.

Transl Res. 2007 Jun;149(6):317-23.PMID: 17543850 [PubMed - indexed for MEDLINE]Related articles

Sp1-mediated transcription is involved in the induction of leptin by insulin-stimulated glucose metabolism.

Moreno-Aliaga MJ, Swarbrick MM, Lorente-Cebrián S, Stanhope KL, Havel PJ, Martínez JA.

J Mol Endocrinol. 2007 May;38(5):537-46.PMID: 17496155 [PubMed - indexed for MEDLINE]Related articlesFree article

Conjugated linoleic acid inhibits glucose metabolism, leptin and adiponectin secretion in primary cultured rat adipocytes.

Pérez-Matute P, Marti A, Martínez JA, Fernández-Otero MP, Stanhope KL, Havel PJ, Moreno-Aliaga MJ.

Mol Cell Endocrinol. 2007 Mar 30;268(1-2):50-8. Epub 2007 Jan 25.PMID: 17321040 [PubMed - indexed for MEDLINE]Related articles

48-h glucose infusion in humans: effect on hormonal responses, hunger and food intake.

Teff KL, Petrova M, Havel PJ, Townsend RR.

Physiol Behav. 2007 Apr 23;90(5):733-43. Epub 2007 Jan 4.PMID: 17275862 [PubMed - indexed for MEDLINE]Related articles

Synergistic effects of conjugated linoleic acid and chromium picolinate improve vascular function and renal pathophysiology in the insulin-resistant JCR:LA-cp rat.

Proctor SD, Kelly SE, Stanhope KL, Havel PJ, Russell JC.

Diabetes Obes Metab. 2007 Jan;9(1):87-95.PMID: 17199723 [PubMed - indexed for MEDLINE]Related articles

Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases.

Beeton C, Wulff H, Standifer NE, Azam P, Mullen KM, Pennington MW, Kolski-Andreaco A, Wei E, Grino A, Counts DR, Wang PH, LeeHealey CJ, S Andrews B, Sankaranarayanan A, Homerick D, Roeck WW, Tehranzadeh J, Stanhope KL, Zimin P, Havel PJ, Griffey S, Knaus HG, Nepom GT, Gutman GA, Calabresi PA, Chandy KG.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17414-9. Epub 2006 Nov 6.PMID: 17088564 [PubMed - indexed for MEDLINE]Related articlesFree article

Circulating concentrations of high-molecular-weight adiponectin are increased following Roux-en-Y gastric bypass surgery.

Swarbrick MM, Austrheim-Smith IT, Stanhope KL, Van Loan MD, Ali MR, Wolfe BM, Havel PJ.

Diabetologia. 2006 Nov;49(11):2552-8. Epub 2006 Sep 21.PMID: 17019599 [PubMed - indexed for MEDLINE]Related articles

Serum adiponectin and coronary heart disease risk in older Black and White Americans.

Kanaya AM, Wassel Fyr C, Vittinghoff E, Havel PJ, Cesari M, Nicklas B, Harris T, Newman AB, Satterfield S, Cummings SR; Health ABC Study.

J Clin Endocrinol Metab. 2006 Dec;91(12):5044-50. Epub 2006 Sep 19.PMID: 16984981 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipogenic human adenovirus-36 reduces leptin expression and secretion and increases glucose uptake by fat cells.

Vangipuram SD, Yu M, Tian J, Stanhope KL, Pasarica M, Havel PJ, Heydari AR, Dhurandhar NV.

Int J Obes (Lond). 2007 Jan;31(1):87-96. Epub 2006 May 16.PMID: 16703005 [PubMed - indexed for MEDLINE]Related articles

Resting energy expenditure and body composition of Labrador Retrievers fed high fat and low fat diets.

Yoo S, Ramsey JJ, Havel PJ, Jones PG, Fascetti AJ.

J Anim Physiol Anim Nutr (Berl). 2006 Jun;90(5-6):185-91.PMID: 16684138 [PubMed - indexed for MEDLINE]Related articles

Multinutrient supplement containing ephedra and caffeine causes weight loss and improves metabolic risk factors in obese women: a randomized controlled trial.

Hackman RM, Havel PJ, Schwartz HJ, Rutledge JC, Watnik MR, Noceti EM, Stohs SJ, Stern JS, Keen CL.

Int J Obes (Lond). 2006 Oct;30(10):1545-56. Epub 2006 Mar 21.PMID: 16552410 [PubMed - indexed for MEDLINE]Related articles

The decrease in C-reactive protein concentration after diet and physical activity induced weight reduction is associated with changes in plasma lipids, but not interleukin-6 or adiponectin.

Dvoráková-Lorenzová A, Suchánek P, Havel PJ, Stávek P, Karasová L, Valenta Z, Tintĕra J, Poledne R.

Metabolism. 2006 Mar;55(3):359-65.PMID: 16483880 [PubMed - indexed for MEDLINE]Related articles

Administration of Lispro insulin with meals improves glycemic control, increases circulating leptin, and suppresses ghrelin, compared with regular/NPH insulin in female patients with type 1 diabetes.

Griffen SC, Oostema K, Stanhope KL, Graham J, Styne DM, Glaser N, Cummings DE, Connors MH, Havel PJ.

J Clin Endocrinol Metab. 2006 Feb;91(2):485-91. Epub 2005 Nov 29.PMID: 16317063 [PubMed - indexed for MEDLINE]Related articlesFree article

Consuming fructose-sweetened beverages increases body adiposity in mice.

Jürgens H, Haass W, Castañeda TR, Schürmann A, Koebnick C, Dombrowski F, Otto B, Nawrocki AR, Scherer PE, Spranger J, Ristow M, Joost HG, Havel PJ, Tschöp MH.

Obes Res. 2005 Jul;13(7):1146-56.PMID: 16076983 [PubMed - indexed for MEDLINE]Related articles

Dietary fructose: implications for dysregulation of energy homeostasis and lipid/carbohydrate metabolism.

Havel PJ.

Nutr Rev. 2005 May;63(5):133-57. Review.PMID: 15971409 [PubMed - indexed for MEDLINE]Related articles

Interleukin-15 stimulates adiponectin secretion by 3T3-L1 adipocytes: evidence for a skeletal muscle-to-fat signaling pathway.

Quinn LS, Strait-Bodey L, Anderson BG, Argilés JM, Havel PJ.

Cell Biol Int. 2005 Jun;29(6):449-57.PMID: 15951205 [PubMed - indexed for MEDLINE]Related articles

Eicosapentaenoic fatty acid increases leptin secretion from primary cultured rat adipocytes: role of glucose metabolism.

Pérez-Matute P, Marti A, Martínez JA, Fernández-Otero MP, Stanhope KL, Havel PJ, Moreno-Aliaga MJ.

Am J Physiol Regul Integr Comp Physiol. 2005 Jun;288(6):R1682-8. Epub 2005 Jan 13.PMID: 15650121 [PubMed - indexed for MEDLINE]Related articles

Circulating leptin and cortisol after burn injury: loss of diurnal pattern.

Hobson KG, Havel PJ, McMurtry AL, Lawless MB, Palmieri TL, Greenhalgh DD.

J Burn Care Rehabil. 2004 Nov-Dec;25(6):491-9.PMID: 15534457 [PubMed - indexed for MEDLINE]Related articles

The yellow agouti mutation alters some but not all responses to diet and exercise.

Chiu S, Fisler JS, Espinal GM, Havel PJ, Stern JS, Warden CH.

Obes Res. 2004 Aug;12(8):1243-55.PMID: 15340107 [PubMed - indexed for MEDLINE]Related articles

Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women.

Teff KL, Elliott SS, Tschöp M, Kieffer TJ, Rader D, Heiman M, Townsend RR, Keim NL, D'Alessio D, Havel PJ.

J Clin Endocrinol Metab. 2004 Jun;89(6):2963-72.PMID: 15181085 [PubMed - indexed for MEDLINE]Related articlesFree article

Update on adipocyte hormones: regulation of energy balance and carbohydrate/lipid metabolism.

Havel PJ.

Diabetes. 2004 Feb;53 Suppl 1:S143-51. Review.PMID: 14749280 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle insulin receptor concentrations in obese patients post bariatric surgery: relationship to hyperinsulinemia.

Pender C, Goldfine ID, Tanner CJ, Pories WJ, MacDonald KG, Havel PJ, Houmard JA, Youngren JF.

Int J Obes Relat Metab Disord. 2004 Mar;28(3):363-9.PMID: 14724657 [PubMed - indexed for MEDLINE]Related articles