PubMed

Symbol nomenclature for glycan representation.

Varki A, Cummings RD, Esko JD, Freeze HH, Stanley P, Marth JD, Bertozzi CR, Hart GW, Etzler ME.

Proteomics. 2009 Nov 9. [Epub ahead of print]PMID: 19902428 [PubMed - as supplied by publisher]Related articles

Enrichment and site-mapping of O-Linked N-Acetylglucosamine by a combination of chemical/enzymatic tagging, photochemical cleavage, and electron transfer dissociation (ETD) mass spectrometry.

Wang Z, Udeshi ND, O'Malley M, Shabanowitz J, Hunt DF, Hart GW.

Mol Cell Proteomics. 2009 Aug 19. [Epub ahead of print]PMID: 19692427 [PubMed - as supplied by publisher]Related articlesFree article

O-linked beta-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress.

Butkinaree C, Park K, Hart GW.

Biochim Biophys Acta. 2009 Aug 6. [Epub ahead of print]PMID: 19647786 [PubMed - as supplied by publisher]Related articles

Regulation of calcium/calmodulin-dependent kinase IV by O-GlcNAc modification.

Dias WB, Cheung WD, Wang Z, Hart GW.

J Biol Chem. 2009 Aug 7;284(32):21327-37. Epub 2009 Jun 8.PMID: 19506079 [PubMed - indexed for MEDLINE]Related articles

O-linked N-acetylglucosamine modification on CCAAT enhancer-binding protein beta: role during adipocyte differentiation.

Li X, Molina H, Huang H, Zhang YY, Liu M, Qian SW, Slawson C, Dias WB, Pandey A, Hart GW, Lane MD, Tang QQ.

J Biol Chem. 2009 Jul 17;284(29):19248-54. Epub 2009 May 28.PMID: 19478079 [PubMed - indexed for MEDLINE]Related articles

A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose.

Housley MP, Udeshi ND, Rodgers JT, Shabanowitz J, Puigserver P, Hunt DF, Hart GW.

J Biol Chem. 2009 Feb 20;284(8):5148-57. Epub 2008 Dec 22.PMID: 19103600 [PubMed - indexed for MEDLINE]Related articles

Two-dimensional gel-based approaches for the assessment of N-Linked and O-GlcNAc glycosylation in human and simian immunodeficiency viruses.

Graham DR, Mitsak MJ, Elliott ST, Chen D, Whelan SA, Hart GW, Van Eyk JE.

Proteomics. 2008 Dec;8(23-24):4919-30.PMID: 19072736 [PubMed - indexed for MEDLINE]Related articles

O-linked GlcNAc modification of cardiac myofilament proteins: a novel regulator of myocardial contractile function.

Ramirez-Correa GA, Jin W, Wang Z, Zhong X, Gao WD, Dias WB, Vecoli C, Hart GW, Murphy AM.

Circ Res. 2008 Dec 5;103(12):1354-8. Epub 2008 Nov 6.PMID: 18988896 [PubMed - indexed for MEDLINE]Related articlesFree article

Site-specific GlcNAcylation of human erythrocyte proteins: potential biomarker(s) for diabetes.

Wang Z, Park K, Comer F, Hsieh-Wilson LC, Saudek CD, Hart GW.

Diabetes. 2009 Feb;58(2):309-17. Epub 2008 Nov 4.PMID: 18984734 [PubMed - indexed for MEDLINE]Related articlesFree article

O-linked beta-N-acetylglucosaminyltransferase substrate specificity is regulated by myosin phosphatase targeting and other interacting proteins.

Cheung WD, Sakabe K, Housley MP, Dias WB, Hart GW.

J Biol Chem. 2008 Dec 5;283(49):33935-41. Epub 2008 Oct 7.PMID: 18840611 [PubMed - indexed for MEDLINE]Related articles

Cross-talk between GlcNAcylation and phosphorylation: site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc.

Wang Z, Gucek M, Hart GW.

Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13793-8. Epub 2008 Sep 8.PMID: 18779572 [PubMed - indexed for MEDLINE]Related articlesFree article

A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin.

Slawson C, Lakshmanan T, Knapp S, Hart GW.

Mol Biol Cell. 2008 Oct;19(10):4130-40. Epub 2008 Jul 23.PMID: 18653473 [PubMed - indexed for MEDLINE]Related articlesFree article

Working group report: the roles of glycans in hemostasis, inflammation and vascular biology.

Varki AP, Baum LG, Bellis SL, Cummings RD, Esko JD, Hart GW, Linhardt RJ, Lowe JB, McEver RP, Srivastava A, Sarkar R.

Glycobiology. 2008 Oct;18(10):747-9. Epub 2008 Jul 11. No abstract available. PMID: 18621991 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of beta-N-acetylglucosaminidase cleavage by caspase-3 during apoptosis.

Butkinaree C, Cheung WD, Park S, Park K, Barber M, Hart GW.

J Biol Chem. 2008 Aug 29;283(35):23557-66. Epub 2008 Jun 27.PMID: 18586680 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of the O-linked beta-N-acetylglucosamine transferase by insulin signaling.

Whelan SA, Lane MD, Hart GW.

J Biol Chem. 2008 Aug 1;283(31):21411-7. Epub 2008 Jun 2.PMID: 18519567 [PubMed - indexed for MEDLINE]Related articlesFree article

Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity.

Copeland RJ, Bullen JW, Hart GW.

Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E17-28. Epub 2008 Apr 29. Review.PMID: 18445751 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection and analysis of proteins modified by O-linked N-acetylglucosamine.

Zachara NE, Cole RN, Hart GW, Gao Y.

Curr Protoc Protein Sci. 2001 Nov;Chapter 12:Unit 12.8.PMID: 18429112 [PubMed - indexed for MEDLINE]Related articles

Detection of glycophospholipid anchors on proteins.

Doering TL, Englund PT, Hart GW.

Curr Protoc Protein Sci. 2001 May;Chapter 12:Unit 12.5.PMID: 18429111 [PubMed - indexed for MEDLINE]Related articles

O-GlcNAc regulates FoxO activation in response to glucose.

Housley MP, Rodgers JT, Udeshi ND, Kelly TJ, Shabanowitz J, Hunt DF, Puigserver P, Hart GW.

J Biol Chem. 2008 Jun 13;283(24):16283-92. Epub 2008 Apr 17.PMID: 18420577 [PubMed - indexed for MEDLINE]Related articlesFree article

Murine platelets are not regulated by O-linked beta-N-acetylglucosamine.

Crawford GL, Hart GW, Whiteheart SW.

Arch Biochem Biophys. 2008 Jun 1;474(1):220-4. Epub 2008 Mar 21.PMID: 18387355 [PubMed - indexed for MEDLINE]Related articlesFree article

AMP-activated protein kinase and p38 MAPK activate O-GlcNAcylation of neuronal proteins during glucose deprivation.

Cheung WD, Hart GW.

J Biol Chem. 2008 May 9;283(19):13009-20. Epub 2008 Mar 19.PMID: 18353774 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardioprotection by N-acetylglucosamine linkage to cellular proteins.

Jones SP, Zachara NE, Ngoh GA, Hill BG, Teshima Y, Bhatnagar A, Hart GW, Marbán E.

Circulation. 2008 Mar 4;117(9):1172-82. Epub 2008 Feb 19.PMID: 18285568 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection and analysis of proteins modified by O-linked N-acetylglucosamine.

Zachara NE, Hart GW, Cole RN, Gao Y.

Curr Protoc Mol Biol. 2002 Feb;Chapter 17:Unit 17.6.PMID: 18265305 [PubMed - indexed for MEDLINE]Related articles

Detection of glycophospholipid anchors on proteins.

Doering TL, Englund PT, Hart GW.

Curr Protoc Mol Biol. 2001 May;Chapter 17:Unit17.8.PMID: 18265164 [PubMed - indexed for MEDLINE]Related articles

O-GlcNAc modification in diabetes and Alzheimer's disease.

Dias WB, Hart GW.

Mol Biosyst. 2007 Nov;3(11):766-72. Epub 2007 Aug 29. Review.PMID: 17940659 [PubMed - indexed for MEDLINE]Related articles

N-propanoylmannosamine interferes with O-GlcNAc modification of the tyrosine 3-monooxygenase and stimulates dopamine secretion.

Bork K, Kannicht C, Nöhring S, Reutter W, Weidemann W, Hart GW, Horstkorte R.

J Neurosci Res. 2008 Feb 15;86(3):647-52.PMID: 17896794 [PubMed - indexed for MEDLINE]Related articles

Dynamic interplay between O-linked N-acetylglucosaminylation and glycogen synthase kinase-3-dependent phosphorylation.

Wang Z, Pandey A, Hart GW.

Mol Cell Proteomics. 2007 Aug;6(8):1365-79. Epub 2007 May 16.PMID: 17507370 [PubMed - indexed for MEDLINE]Related articlesFree article

Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins.

Hart GW, Housley MP, Slawson C.

Nature. 2007 Apr 26;446(7139):1017-22. Review.PMID: 17460662 [PubMed - indexed for MEDLINE]Related articles

Identification of O-GlcNAc sites on proteins.

Whelan SA, Hart GW.

Methods Enzymol. 2006;415:113-33.PMID: 17116471 [PubMed - indexed for MEDLINE]Related articles

Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats.

Akimoto Y, Hart GW, Wells L, Vosseller K, Yamamoto K, Munetomo E, Ohara-Imaizumi M, Nishiwaki C, Nagamatsu S, Hirano H, Kawakami H.

Glycobiology. 2007 Feb;17(2):127-40. Epub 2006 Nov 9.PMID: 17095531 [PubMed - indexed for MEDLINE]Related articlesFree article

Reciprocal keratin 18 Ser48 O-GlcNAcylation and Ser52 phosphorylation using peptide analysis.

Tao GZ, Kirby C, Whelan SA, Rossi F, Bi X, MacLaren M, Gentalen E, O'Neill RA, Hart GW, Omary MB.

Biochem Biophys Res Commun. 2006 Dec 22;351(3):708-12. Epub 2006 Oct 27.PMID: 17084817 [PubMed - indexed for MEDLINE]Related articlesFree article

Fine-tuning ER-beta structure with PTMs.

Hart GW, Sakabe K.

Chem Biol. 2006 Sep;13(9):923-4.PMID: 16984879 [PubMed - indexed for MEDLINE]Related articles

Cell signaling, the essential role of O-GlcNAc!

Zachara NE, Hart GW.

Biochim Biophys Acta. 2006 May-Jun;1761(5-6):599-617. Epub 2006 May 6. Review.PMID: 16781888 [PubMed - indexed for MEDLINE]Related articles

Sweet insights into learning and memory.

Hart GW.

Nat Chem Biol. 2006 Feb;2(2):67-8. No abstract available. PMID: 16421584 [PubMed - indexed for MEDLINE]Related articles

Posttranslational, reversible O-glycosylation is stimulated by high glucose and mediates plasminogen activator inhibitor-1 gene expression and Sp1 transcriptional activity in glomerular mesangial cells.

Goldberg HJ, Whiteside CI, Hart GW, Fantus IG.

Endocrinology. 2006 Jan;147(1):222-31. Erratum in: Endocrinology. 2006 Nov;147(11):5490. PMID: 16365142 [PubMed - indexed for MEDLINE]Related articlesFree article

O-GlcNAc cycling: how a single sugar post-translational modification is changing the way we think about signaling networks.

Slawson C, Housley MP, Hart GW.

J Cell Biochem. 2006 Jan 1;97(1):71-83. Review.PMID: 16237703 [PubMed - indexed for MEDLINE]Related articles

Perturbations in O-linked beta-N-acetylglucosamine protein modification cause severe defects in mitotic progression and cytokinesis.

Slawson C, Zachara NE, Vosseller K, Cheung WD, Lane MD, Hart GW.

J Biol Chem. 2005 Sep 23;280(38):32944-56. Epub 2005 Jul 18.PMID: 16027160 [PubMed - indexed for MEDLINE]Related articlesFree article

O-GlcNAc modification of nucleocytoplasmic proteins and diabetes.

Akimoto Y, Hart GW, Hirano H, Kawakami H.

Med Mol Morphol. 2005 Jun;38(2):84-91. Review.PMID: 15944815 [PubMed - indexed for MEDLINE]Related articles

Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol.

Vosseller K, Hansen KC, Chalkley RJ, Trinidad JC, Wells L, Hart GW, Burlingame AL.

Proteomics. 2005 Feb;5(2):388-98.PMID: 15648052 [PubMed - indexed for MEDLINE]Related articles

O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease.

Liu F, Iqbal K, Grundke-Iqbal I, Hart GW, Gong CX.

Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10804-9. Epub 2004 Jul 12.PMID: 15249677 [PubMed - indexed for MEDLINE]Related articlesFree article

O-GlcNAc transferase is in a functional complex with protein phosphatase 1 catalytic subunits.

Wells L, Kreppel LK, Comer FI, Wadzinski BE, Hart GW.

J Biol Chem. 2004 Sep 10;279(37):38466-70. Epub 2004 Jul 7.PMID: 15247246 [PubMed - indexed for MEDLINE]Related articlesFree article

O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress.

Zachara NE, Hart GW.

Biochim Biophys Acta. 2004 Jul 6;1673(1-2):13-28. Review.PMID: 15238246 [PubMed - indexed for MEDLINE]Related articles

Nucleocytoplasmic glycosylation, O-GlcNAc: identification and site mapping.

Zachara NE, Cheung WD, Hart GW.

Methods Mol Biol. 2004;284:175-94.PMID: 15173616 [PubMed - indexed for MEDLINE]Related articles

Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells.

Zachara NE, O'Donnell N, Cheung WD, Mercer JJ, Marth JD, Hart GW.

J Biol Chem. 2004 Jul 16;279(29):30133-42. Epub 2004 May 11.PMID: 15138254 [PubMed - indexed for MEDLINE]Related articlesFree article

O-GlcNAc modification: a nutritional sensor that modulates proteasome function.

Zachara NE, Hart GW.

Trends Cell Biol. 2004 May;14(5):218-21.PMID: 15130576 [PubMed - indexed for MEDLINE]Related articles

Glycobiology and cancer: meeting summary and future diections.

Hart GW, Lowe JB, Sathyamoorthy N.

Cancer Biol Ther. 2004 Feb;3(2):233-7. Epub 2004 Feb 1. No abstract available. PMID: 14764992 [PubMed - indexed for MEDLINE]Related articlesFree article

Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability.

O'Donnell N, Zachara NE, Hart GW, Marth JD.

Mol Cell Biol. 2004 Feb;24(4):1680-90.PMID: 14749383 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteomic approaches to analyze the dynamic relationships between nucleocytoplasmic protein glycosylation and phosphorylation.

Whelan SA, Hart GW.

Circ Res. 2003 Nov 28;93(11):1047-58. Review.PMID: 14645135 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynamic interplay between O-GlcNAc and O-phosphate: the sweet side of protein regulation.

Slawson C, Hart GW.

Curr Opin Struct Biol. 2003 Oct;13(5):631-6. Review.PMID: 14568619 [PubMed - indexed for MEDLINE]Related articles

O-linked N-acetylglucosamine and cancer: messages from the glycosylation of c-Myc.

Chou TY, Hart GW.

Adv Exp Med Biol. 2001;491:413-8. Review.PMID: 14533811 [PubMed - indexed for MEDLINE]Related articles