PubMed

Reappraising the stereotypes of diabetes in the modern diabetogenic environment.

Wentworth JM, Fourlanos S, Harrison LC.

Nat Rev Endocrinol. 2009 Sep;5(9):483-9. Epub 2009 Jul 28. Review.PMID: 19636326 [PubMed - indexed for MEDLINE]Related articles

Non-Hodgkin lymphoma response evaluation with MRI texture classification.

Harrison LC, Luukkaala T, Pertovaara H, Saarinen TO, Heinonen TT, Järvenpää R, Soimakallio S, Kellokumpu-Lehtinen PL, Eskola HJ, Dastidar P.

J Exp Clin Cancer Res. 2009 Jun 22;28:87.PMID: 19545438 [PubMed - indexed for MEDLINE]Related articlesFree article

The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes.

Mannering SI, Pang SH, Williamson NA, Naselli G, Reynolds EC, O'Brien-Simpson NM, Purcell AW, Harrison LC.

Clin Exp Immunol. 2009 May;156(2):226-31. Epub 2009 Mar 9.PMID: 19292763 [PubMed - indexed for MEDLINE]Related articles

Immune characterization of an individual with an exceptionally high natural killer T cell frequency and her immediate family.

Chan AC, Serwecinska L, Cochrane A, Harrison LC, Godfrey DI, Berzins SP.

Clin Exp Immunol. 2009 May;156(2):238-45. Epub 2009 Jan 22.PMID: 19250277 [PubMed - indexed for MEDLINE]Related articles

Congenital rubella, diabetes and HLA.

Honeyman MC, Harrison LC.

Diabetologia. 2009 Feb;52(2):371-2; author reply 373. Epub 2008 Nov 20. No abstract available. PMID: 19020858 [PubMed - indexed for MEDLINE]Related articles

Weight gain in early life predicts risk of islet autoimmunity in children with a first-degree relative with type 1 diabetes.

Couper JJ, Beresford S, Hirte C, Baghurst PA, Pollard A, Tait BD, Harrison LC, Colman PG.

Diabetes Care. 2009 Jan;32(1):94-9. Epub 2008 Oct 3.PMID: 18835948 [PubMed - in process]Related articlesFree article

Vascularized tissue-engineered chambers promote survival and function of transplanted islets and improve glycemic control.

Knight KR, Uda Y, Findlay MW, Brown DL, Cronin KJ, Jamieson E, Tai T, Keramidaris E, Penington AJ, Rophael J, Harrison LC, Morrison WA.

FASEB J. 2008 Oct;22(10):3747. No abstract available. PMID: 18827031 [PubMed - indexed for MEDLINE]Related articlesFree article

Dominance of cytokine- over FasL-induced impairment of the mitochondrial transmembrane potential (Deltapsim) in the pancreatic beta-cell line NIT-1.

Augstein P, Heinke P, Salzsieder E, Grimm R, Giebel J, Salzsieder C, Harrison LC.

Diab Vasc Dis Res. 2008 Sep;5(3):198-204.PMID: 18777493 [PubMed - indexed for MEDLINE]Related articles

Pancreatic expression and mitochondrial localization of the progestin-adipoQ receptor PAQR10.

Góñez LJ, Naselli G, Banakh I, Niwa H, Harrison LC.

Mol Med. 2008 Nov-Dec;14(11-12):697-704. Epub 2008 Aug 20.PMID: 18769639 [PubMed - indexed for MEDLINE]Related articlesFree article

The accelerator hypothesis and increasing incidence of type 1 diabetes.

Fourlanos S, Harrison LC, Colman PG.

Curr Opin Endocrinol Diabetes Obes. 2008 Aug;15(4):321-5. Review.PMID: 18594271 [PubMed - indexed for MEDLINE]Related articles

Type 1 diabetes: lessons for other autoimmune diseases?

Harrison LC, Honeyman MC, Morahan G, Wentworth JM, Elkassaby S, Colman PG, Fourlanos S.

J Autoimmun. 2008 Nov;31(3):306-10. Epub 2008 Jun 16.PMID: 18558477 [PubMed - indexed for MEDLINE]Related articles

Adjuvant Radiation Therapy of Retroperitoneal Sarcoma: The Role of Intraoperative Radiotherapy (IORT).

Hu KS, Harrison LC.

Sarcoma. 2000;4(1-2):11-6.PMID: 18521429 [PubMed - in process]Related articlesFree article

The rising incidence of type 1 diabetes is accounted for by cases with lower-risk human leukocyte antigen genotypes.

Fourlanos S, Varney MD, Tait BD, Morahan G, Honeyman MC, Colman PG, Harrison LC.

Diabetes Care. 2008 Aug;31(8):1546-9. Epub 2008 May 16.PMID: 18487476 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice.

Krishnamurthy B, Mariana L, Gellert SA, Colman PG, Harrison LC, Lew AM, Santamaria P, Thomas HE, Kay TW.

J Immunol. 2008 Apr 1;180(7):4458-64.PMID: 18354167 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of spectral irradiance standards used to calibrate shortwave radiometers and spectroradiometers.

Kiedron PW, Michalsky JJ, Berndt JL, Harrison LC.

Appl Opt. 1999 Apr 20;38(12):2432-9.PMID: 18319808 [PubMed - in process]Related articles

Vaccination against self to prevent autoimmune disease: the type 1 diabetes model.

Harrison LC.

Immunol Cell Biol. 2008 Feb;86(2):139-45. Epub 2008 Jan 8. Review.PMID: 18180798 [PubMed - indexed for MEDLINE]Related articles

Seasonal changes in preprandial glucose, A1C, and blood pressure in diabetic patients: response to Liang.

Honeyman MC, Elkassaby S, Harrison LC.

Diabetes Care. 2007 Nov;30(11):e118; author reply e119. No abstract available. PMID: 17965302 [PubMed - indexed for MEDLINE]Related articlesFree article

Endocrine cells develop within pancreatic bud-like structures derived from mouse ES cells differentiated in response to BMP4 and retinoic acid.

Micallef SJ, Li X, Janes ME, Jackson SA, Sutherland RM, Lew AM, Harrison LC, Elefanty AG, Stanley EG.

Stem Cell Res. 2007 Oct;1(1):25-36. Epub 2007 Aug 3.PMID: 19383384 [PubMed - indexed for MEDLINE]Related articles

Homeostatic proliferation of intestinal intraepithelial lymphocytes precedes their migration to extra-intestinal sites.

Stankovic S, Zhan Y, Harrison LC.

Eur J Immunol. 2007 Aug;37(8):2226-33.PMID: 17595677 [PubMed - indexed for MEDLINE]Related articles

Does insulin resistance need resistin?

Wentworth JM, Harrison LC.

J Clin Endocrinol Metab. 2007 Jun;92(6):2036-7. No abstract available. PMID: 17554055 [PubMed - indexed for MEDLINE]Related articlesFree article

Mucosal tolerance to prevent type 1 diabetes: can the outcome be improved in humans?

Hanninen A, Harrison LC.

Rev Diabet Stud. 2004 Fall;1(3):113-21. Epub 2004 Nov 10.PMID: 17491673 [PubMed]Related articlesFree article

The origin of thymic CD4+CD25+ regulatory T cells and their co-stimulatory requirements are determined after elimination of recirculating peripheral CD4+ cells.

Zhan Y, Bourges D, Dromey JA, Harrison LC, Lew AM.

Int Immunol. 2007 Apr;19(4):455-63. Epub 2007 Feb 20.PMID: 17314081 [PubMed - indexed for MEDLINE]Related articlesFree article

Cognate CD4+ help elicited by resting dendritic cells does not impair the induction of peripheral tolerance in CD8+ T cells.

Steptoe RJ, Ritchie JM, Wilson NS, Villadangos JA, Lew AM, Harrison LC.

J Immunol. 2007 Feb 15;178(4):2094-103.PMID: 17277113 [PubMed - indexed for MEDLINE]Related articlesFree article

Pre-type 1 diabetes dysmetabolism: maximal sensitivity achieved with both oral and intravenous glucose tolerance testing.

Barker JM, McFann K, Harrison LC, Fourlanos S, Krischer J, Cuthbertson D, Chase HP, Eisenbarth GS; DPT-1 Study Group.

J Pediatr. 2007 Jan;150(1):31-36.e6.PMID: 17188609 [PubMed - indexed for MEDLINE]Related articlesFree article

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

Krishnamurthy B, Dudek NL, McKenzie MD, Purcell AW, Brooks AG, Gellert S, Colman PG, Harrison LC, Lew AM, Thomas HE, Kay TW.

J Clin Invest. 2006 Dec;116(12):3258-65.PMID: 17143333 [PubMed - indexed for MEDLINE]Related articlesFree article

Proinsulin is encoded by an RNA splice variant in human blood myeloid cells.

Narendran P, Neale AM, Lee BH, Ngui K, Steptoe RJ, Morahan G, Madsen O, Dromey JA, Jensen KP, Harrison LC.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16430-5. Epub 2006 Oct 19.PMID: 17053071 [PubMed - indexed for MEDLINE]Related articlesFree article

The prospect of vaccination to prevent type 1 diabetes.

Harrison LC.

Hum Vaccin. 2005 Jul-Aug;1(4):143-50. Epub 2005 Jul 18. Review.PMID: 17012869 [PubMed - indexed for MEDLINE]Related articlesFree article

TCR gamma delta intraepithelial lymphocytes are required for self-tolerance.

Locke NR, Stankovic S, Funda DP, Harrison LC.

J Immunol. 2006 Jun 1;176(11):6553-9.PMID: 16709812 [PubMed - indexed for MEDLINE]Related articlesFree article

A clinical screening tool identifies autoimmune diabetes in adults.

Fourlanos S, Perry C, Stein MS, Stankovich J, Harrison LC, Colman PG.

Diabetes Care. 2006 May;29(5):970-5.PMID: 16644622 [PubMed - indexed for MEDLINE]Related articlesFree article

Intranasal vaccination with proinsulin DNA induces regulatory CD4+ T cells that prevent experimental autoimmune diabetes.

Every AL, Kramer DR, Mannering SI, Lew AM, Harrison LC.

J Immunol. 2006 Apr 15;176(8):4608-15.PMID: 16585551 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascularized tissue-engineered chambers promote survival and function of transplanted islets and improve glycemic control.

Knight KR, Uda Y, Findlay MW, Brown DL, Cronin KJ, Jamieson E, Tai T, Keramidaris E, Penington AJ, Rophael J, Harrison LC, Morrison WA.

FASEB J. 2006 Mar;20(3):565-7. Epub 2006 Jan 25. Erratum in: FASEB J. 2008 May;22(5):1618. PMID: 16436466 [PubMed - indexed for MEDLINE]Related articlesFree article

The insulin A-chain epitope recognized by human T cells is posttranslationally modified.

Mannering SI, Harrison LC, Williamson NA, Morris JS, Thearle DJ, Jensen KP, Kay TW, Rossjohn J, Falk BA, Nepom GT, Purcell AW.

J Exp Med. 2005 Nov 7;202(9):1191-7. Epub 2005 Oct 31.PMID: 16260488 [PubMed - indexed for MEDLINE]Related articlesFree article

Fuzzy neural network-based prediction of the motif for MHC class II binding peptides.

Noguchi H, Hanai T, Honda H, Harrison LC, Kobayashi T.

J Biosci Bioeng. 2001;92(3):227-31.PMID: 16233088 [PubMed]Related articlesFree article

Latent autoimmune diabetes in adults (LADA) should be less latent.

Fourlanos S, Dotta F, Greenbaum CJ, Palmer JP, Rolandsson O, Colman PG, Harrison LC.

Diabetologia. 2005 Nov;48(11):2206-12. Epub 2005 Sep 29. Review.PMID: 16193284 [PubMed - indexed for MEDLINE]Related articles

Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas.

Holland AM, Góñez LJ, Naselli G, Macdonald RJ, Harrison LC.

Diabetes. 2005 Sep;54(9):2586-95.PMID: 16123346 [PubMed - indexed for MEDLINE]Related articlesFree article

Pulmonary CD4+ cytokine responses in mice reveal differences in the relative immunogenicity of cold-adapted influenza A vaccine donor strains.

Wareing MD, Harrison LC, Tannock GA.

Vaccine. 2005 Jul 1;23(31):4075-81. Epub 2005 Apr 7.PMID: 15963362 [PubMed - indexed for MEDLINE]Related articles

Convergence of bone morphogenetic protein and laminin-1 signaling pathways promotes proliferation and colony formation by fetal mouse pancreatic cells.

Jiang FX, Harrison LC.

Exp Cell Res. 2005 Aug 1;308(1):114-22.PMID: 15913604 [PubMed - indexed for MEDLINE]Related articles

An efficient method for cloning human autoantigen-specific T cells.

Mannering SI, Dromey JA, Morris JS, Thearle DJ, Jensen KP, Harrison LC.

J Immunol Methods. 2005 Mar;298(1-2):83-92.PMID: 15847799 [PubMed - indexed for MEDLINE]Related articles

Laminin-1 and epidermal growth factor family members co-stimulate fetal pancreas cell proliferation and colony formation.

Jiang FX, Harrison LC.

Differentiation. 2005 Feb;73(1):45-9.PMID: 15733067 [PubMed - indexed for MEDLINE]Related articles

CD4+ T cell proliferation in response to GAD and proinsulin in healthy, pre-diabetic, and diabetic donors.

Mannering SI, Morris JS, Stone NL, Jensen KP, VAN Endert PM, Harrison LC.

Ann N Y Acad Sci. 2004 Dec;1037:16-21.PMID: 15699488 [PubMed - indexed for MEDLINE]Related articles

Fms-like tyrosine kinase 3 ligand administration overcomes a genetically determined dendritic cell deficiency in NOD mice and protects against diabetes development.

O'Keeffe M, Brodnicki TC, Fancke B, Vremec D, Morahan G, Maraskovsky E, Steptoe R, Harrison LC, Shortman K.

Int Immunol. 2005 Mar;17(3):307-14. Epub 2005 Jan 31.PMID: 15684037 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoimmune diabetes is suppressed by transfer of proinsulin-encoding Gr-1+ myeloid progenitor cells that differentiate in vivo into resting dendritic cells.

Steptoe RJ, Ritchie JM, Jones LK, Harrison LC.

Diabetes. 2005 Feb;54(2):434-42.PMID: 15677501 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokines activate caspase-3 in insulinoma cells of diabetes-prone NOD mice directly and via upregulation of Fas.

Augstein P, Bahr J, Wachlin G, Heinke P, Berg S, Salzsieder E, Harrison LC.

J Autoimmun. 2004 Dec;23(4):301-9.PMID: 15571924 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance is a risk factor for progression to type 1 diabetes.

Fourlanos S, Narendran P, Byrnes GB, Colman PG, Harrison LC.

Diabetologia. 2004 Oct;47(10):1661-7. Epub 2004 Oct 6. Erratum in: Diabetologia. 2004 Dec;47(12):2247. PMID: 15480539 [PubMed - indexed for MEDLINE]Related articles

Harp (harmonin-interacting, ankyrin repeat-containing protein), a novel protein that interacts with harmonin in epithelial tissues.

Johnston AM, Naselli G, Niwa H, Brodnicki T, Harrison LC, Góñez LJ.

Genes Cells. 2004 Oct;9(10):967-82.PMID: 15461667 [PubMed - indexed for MEDLINE]Related articles

Pancreatic beta-cell function and immune responses to insulin after administration of intranasal insulin to humans at risk for type 1 diabetes.

Harrison LC, Honeyman MC, Steele CE, Stone NL, Sarugeri E, Bonifacio E, Couper JJ, Colman PG.

Diabetes Care. 2004 Oct;27(10):2348-55.PMID: 15451899 [PubMed - indexed for MEDLINE]Related articlesFree article

TCR-mediated activation promotes GITR upregulation in T cells and resistance to glucocorticoid-induced death.

Zhan Y, Funda DP, Every AL, Fundova P, Purton JF, Liddicoat DR, Cole TJ, Godfrey DI, Brady JL, Mannering SI, Harrison LC, Lew AM.

Int Immunol. 2004 Sep;16(9):1315-21. Epub 2004 Jul 19.PMID: 15262900 [PubMed - indexed for MEDLINE]Related articlesFree article

Fas ligand down-regulates cytokine-induced Fas receptor expression on insulinoma (NIT-1), but not islet cells, from autoimmune nonobese diabetic mice.

Augstein P, Heinke P, Salzsieder E, Berg S, Rettig R, Salzsieder C, Harrison LC.

Endocrinology. 2004 Jun;145(6):2747-52. Epub 2004 Mar 19.PMID: 15033908 [PubMed - indexed for MEDLINE]Related articlesFree article

Screening for preclinical type 1 diabetes in a discrete population with an apparent increased disease incidence.

Colman PG, McNair P, King J, Caudwell J, Jankulovski C, Tait BD, Honeyman MC, Harrison LC.

Pediatr Diabetes. 2000 Dec;1(4):193-8.PMID: 15016215 [PubMed]Related articles

Risk assessment, prediction and prevention of type 1 diabetes.

Harrison LC.

Pediatr Diabetes. 2001 Jun;2(2):71-82.PMID: 15016201 [PubMed]Related articles