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Molecular Prognostic Testing and Individualized Patient Care in Uveal Melanoma.

Harbour JW.

Am J Ophthalmol. 2009 Oct 1. [Epub ahead of print]PMID: 19800609 [PubMed - as supplied by publisher]Related articles

Hepatic metastasis from uveal melanoma: angiographic pattern predictive of survival after hepatic arterial chemoembolization.

Dayani PN, Gould JE, Brown DB, Sharma KV, Linette GP, Harbour JW.

Arch Ophthalmol. 2009 May;127(5):628-32.PMID: 19433711 [PubMed - indexed for MEDLINE]Related articles

Emerging insights into the molecular pathogenesis of uveal melanoma.

Landreville S, Agapova OA, Harbour JW.

Future Oncol. 2008 Oct;4(5):629-36. Review.PMID: 18922120 [PubMed - indexed for MEDLINE]Related articlesFree article

Oncogenic mutations in GNAQ occur early in uveal melanoma.

Onken MD, Worley LA, Long MD, Duan S, Council ML, Bowcock AM, Harbour JW.

Invest Ophthalmol Vis Sci. 2008 Dec;49(12):5230-4. Epub 2008 Aug 21.PMID: 18719078 [PubMed - indexed for MEDLINE]Related articles

Comment on "Lowpenetrant RB allele in small-cell cancer shows geldanamycin instability and discordant expression with mutant ras" by Park et al.

Harbour JW.

Cell Cycle. 2008 Aug;7(15):2276-7. No abstract available. PMID: 18682685 [PubMed - indexed for MEDLINE]Related articles

A metastasis modifier locus on human chromosome 8p in uveal melanoma identified by integrative genomic analysis.

Onken MD, Worley LA, Harbour JW.

Clin Cancer Res. 2008 Jun 15;14(12):3737-45.PMID: 18559591 [PubMed - indexed for MEDLINE]Related articlesFree article

Correlation study of benign cytomorphology and final clinical diagnosis.

Zhai J, Harbour JW, Smith ME, Dávila RM.

Acta Cytol. 2008 Mar-Apr;52(2):196-200.PMID: 18499993 [PubMed - indexed for MEDLINE]Related articles

Prognostic biomarkers in uveal melanoma: evidence for a stem cell-like phenotype associated with metastasis.

Chang SH, Worley LA, Onken MD, Harbour JW.

Melanoma Res. 2008 Jun;18(3):191-200.PMID: 18477893 [PubMed - indexed for MEDLINE]Related articles

Micro-RNAs associated with metastasis in uveal melanoma identified by multiplexed microarray profiling.

Worley LA, Long MD, Onken MD, Harbour JW.

Melanoma Res. 2008 Jun;18(3):184-90.PMID: 18477892 [PubMed - indexed for MEDLINE]Related articles

Tilting of radioactive plaques after initial accurate placement for treatment of uveal melanoma.

Almony A, Breit S, Zhao H, Garcia-Ramirez J, Mansur DB, Harbour JW.

Arch Ophthalmol. 2008 Jan;126(1):65-70.PMID: 18195220 [PubMed - indexed for MEDLINE]Related articlesFree article

Integrative genomic analysis of aneuploidy in uveal melanoma.

Ehlers JP, Worley L, Onken MD, Harbour JW.

Clin Cancer Res. 2008 Jan 1;14(1):115-22.PMID: 18172260 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic arterial chemoembolization for management of metastatic melanoma.

Sharma KV, Gould JE, Harbour JW, Linette GP, Pilgram TK, Dayani PN, Brown DB.

AJR Am J Roentgenol. 2008 Jan;190(1):99-104.PMID: 18094299 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular prognostic testing in uveal melanoma: has it finally come of age?

Harbour JW.

Arch Ophthalmol. 2007 Aug;125(8):1122-3. No abstract available. PMID: 17698762 [PubMed - indexed for MEDLINE]Related articles

Inhibiting angiogenesis in retinoblastoma.

Apte RS, Harbour JW.

Ophthalmic Res. 2007;39(4):188-90. Epub 2007 Jun 6. Review. No abstract available. PMID: 17556838 [PubMed - indexed for MEDLINE]Related articles

Loss of heterozygosity of chromosome 3 detected with single nucleotide polymorphisms is superior to monosomy 3 for predicting metastasis in uveal melanoma.

Onken MD, Worley LA, Person E, Char DH, Bowcock AM, Harbour JW.

Clin Cancer Res. 2007 May 15;13(10):2923-7.PMID: 17504992 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptomic versus chromosomal prognostic markers and clinical outcome in uveal melanoma.

Worley LA, Onken MD, Person E, Robirds D, Branson J, Char DH, Perry A, Harbour JW.

Clin Cancer Res. 2007 Mar 1;13(5):1466-71.PMID: 17332290 [PubMed - indexed for MEDLINE]Related articlesFree article

Rb at the interface between cell cycle and apoptotic decisions.

Delston RB, Harbour JW.

Curr Mol Med. 2006 Nov;6(7):713-8. Review.PMID: 17100597 [PubMed - indexed for MEDLINE]Related articles

Prognostic testing in uveal melanoma by transcriptomic profiling of fine needle biopsy specimens.

Onken MD, Worley LA, Dávila RM, Char DH, Harbour JW.

J Mol Diagn. 2006 Nov;8(5):567-73.PMID: 17065425 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment outcomes for primary intraocular lymphoma: implications for external beam radiotherapy.

Berenbom A, Davila RM, Lin HS, Harbour JW.

Eye (Lond). 2007 Sep;21(9):1198-201. Epub 2006 May 26.PMID: 16732210 [PubMed - indexed for MEDLINE]Related articles

Functional gene expression analysis uncovers phenotypic switch in aggressive uveal melanomas.

Onken MD, Ehlers JP, Worley LA, Makita J, Yokota Y, Harbour JW.

Cancer Res. 2006 May 1;66(9):4602-9.PMID: 16651410 [PubMed - indexed for MEDLINE]Related articlesFree article

Eye cancer: unique insights into oncogenesis: the Cogan Lecture.

Harbour JW.

Invest Ophthalmol Vis Sci. 2006 May;47(5):1736-45. Review. No abstract available. PMID: 16638975 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipid exudation following plaque radiotherapy for posterior uveal melanoma.

Mills MD, Harbour JW.

Am J Ophthalmol. 2006 Mar;141(3):594-595.PMID: 16490526 [PubMed - indexed for MEDLINE]Related articles

Molecular pathobiology of uveal melanoma.

Ehlers JP, Harbour JW.

Int Ophthalmol Clin. 2006 Winter;46(1):167-80. Review. No abstract available. PMID: 16365562 [PubMed - indexed for MEDLINE]Related articles

Association between microarray gene expression signature and extravascular matrix patterns in primary uveal melanomas.

Onken MD, Lin AY, Worley LA, Folberg R, Harbour JW.

Am J Ophthalmol. 2005 Oct;140(4):748-9.PMID: 16226537 [PubMed - indexed for MEDLINE]Related articles

Fine needle aspiration biopsy with adjunct immunohistochemistry in intraocular tumor management.

Faulkner-Jones BE, Foster WJ, Harbour JW, Smith ME, Dávila RM.

Acta Cytol. 2005 May-Jun;49(3):297-308.PMID: 15966293 [PubMed - indexed for MEDLINE]Related articles

DDEF1 is located in an amplified region of chromosome 8q and is overexpressed in uveal melanoma.

Ehlers JP, Worley L, Onken MD, Harbour JW.

Clin Cancer Res. 2005 May 15;11(10):3609-13.PMID: 15897555 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional analysis of the p53 pathway in response to ionizing radiation in uveal melanoma.

Sun Y, Tran BN, Worley LA, Delston RB, Harbour JW.

Invest Ophthalmol Vis Sci. 2005 May;46(5):1561-4.PMID: 15851551 [PubMed - indexed for MEDLINE]Related articlesFree article

Uveal melanoma: genetic aspects.

Singh AD, Damato B, Howard P, Harbour JW.

Ophthalmol Clin North Am. 2005 Mar;18(1):85-97, viii. Review.PMID: 15763194 [PubMed - indexed for MEDLINE]Related articles

NBS1 expression as a prognostic marker in uveal melanoma.

Ehlers JP, Harbour JW.

Clin Cancer Res. 2005 Mar 1;11(5):1849-53.PMID: 15756009 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase.

Lieman JH, Worley LA, Harbour JW.

J Biol Chem. 2005 Mar 18;280(11):10484-90. Epub 2005 Jan 7.PMID: 15640164 [PubMed - indexed for MEDLINE]Related articlesFree article

MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A.

Loercher AE, Tank EM, Delston RB, Harbour JW.

J Cell Biol. 2005 Jan 3;168(1):35-40. Epub 2004 Dec 28.PMID: 15623583 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death.

Onken MD, Worley LA, Ehlers JP, Harbour JW.

Cancer Res. 2004 Oct 15;64(20):7205-9.PMID: 15492234 [PubMed - indexed for MEDLINE]Related articlesFree article

What is the best treatment for retinoblastoma?

Harbour JW.

Am J Ophthalmol. 2004 Sep;138(3):471-3. No abstract available. PMID: 15364232 [PubMed - indexed for MEDLINE]Related articles

Cytologic diagnosis of intraocular lymphoma in vitreous aspirates.

Farkas T, Harbour JW, Dávila RM.

Acta Cytol. 2004 Jul-Aug;48(4):487-91.PMID: 15296338 [PubMed - indexed for MEDLINE]Related articles

Photodynamic therapy for choroidal metastasis from carcinoid tumor.

Harbour JW.

Am J Ophthalmol. 2004 Jun;137(6):1143-5.PMID: 15183811 [PubMed - indexed for MEDLINE]Related articles

For whom the bell tolls: susceptibility to common adult cancers in retinoblastoma survivors.

Kaye FJ, Harbour JW.

J Natl Cancer Inst. 2004 Mar 3;96(5):342-3. No abstract available. PMID: 14996847 [PubMed - indexed for MEDLINE]Related articlesFree article

Optical coherence tomography in the evaluation of retinal changes associated with suspicious choroidal melanocytic tumors.

Espinoza G, Rosenblatt B, Harbour JW.

Am J Ophthalmol. 2004 Jan;137(1):90-5.PMID: 14700649 [PubMed - indexed for MEDLINE]Related articles

Association between choroidal pigmentation and posterior uveal melanoma in a white population.

Harbour JW, Brantley MA Jr, Hollingsworth H, Gordon M.

Br J Ophthalmol. 2004 Jan;88(1):39-43.PMID: 14693770 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi.

Harbour JW, Brantley MA Jr, Hollingsworth H, Gordon M.

Br J Ophthalmol. 2004 Jan;88(1):36-8.PMID: 14693769 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular genetics of uveal melanoma.

Loercher AE, Harbour JW.

Curr Eye Res. 2003 Aug;27(2):69-74. Review.PMID: 14632157 [PubMed - indexed for MEDLINE]Related articles

Transpupillary thermotherapy versus plaque radiotherapy for suspected choroidal melanomas.

Harbour JW, Meredith TA, Thompson PA, Gordon ME.

Ophthalmology. 2003 Nov;110(11):2207-14; discussion 2215.PMID: 14597531 [PubMed - indexed for MEDLINE]Related articles

Pars plana vitrectomy in eyes containing a treated posterior uveal melanoma.

Foster WJ, Harbour JW, Holekamp NM, Shah GK, Thomas MA.

Am J Ophthalmol. 2003 Sep;136(3):471-6.PMID: 12967800 [PubMed - indexed for MEDLINE]Related articles

Status of the NF1 tumor suppressor locus in uveal melanoma.

Foster WJ, Fuller CE, Perry A, Harbour JW.

Arch Ophthalmol. 2003 Sep;121(9):1311-5.PMID: 12963615 [PubMed - indexed for MEDLINE]Related articlesFree article

Ocular melanoma: a review and the relationship to cutaneous melanoma.

Hurst EA, Harbour JW, Cornelius LA.

Arch Dermatol. 2003 Aug;139(8):1067-73. Review.PMID: 12925397 [PubMed - indexed for MEDLINE]Related articles

Distinct mechanisms for regulating the tumor suppressor and antiapoptotic functions of Rb.

Ma D, Zhou P, Harbour JW.

J Biol Chem. 2003 May 23;278(21):19358-66. Epub 2003 Mar 19.PMID: 12646568 [PubMed - indexed for MEDLINE]Related articlesFree article

Rate of resolution of exudative retinal detachment after plaque radiotherapy for uveal melanoma.

Harbour JW, Ahmad S, El-Bash M.

Arch Ophthalmol. 2002 Nov;120(11):1463-9. Erratum in: Arch Ophthalmol. 2003 Feb;121(2):297.. PMID: 12427058 [PubMed - indexed for MEDLINE]Related articles

Transducible peptide therapy for uveal melanoma and retinoblastoma.

Harbour JW, Worley L, Ma D, Cohen M.

Arch Ophthalmol. 2002 Oct;120(10):1341-6.PMID: 12365913 [PubMed - indexed for MEDLINE]Related articles

Photodynamic therapy for circumscribed choroidal hemangioma.

Sheidow TG, Harbour JW.

Can J Ophthalmol. 2002 Aug;37(5):314-7. No abstract available. PMID: 12322864 [PubMed - indexed for MEDLINE]Related articles

Altered expression of Rb and p53 in uveal melanomas following plaque radiotherapy.

Brantley MA Jr, Worley L, Harbour JW.

Am J Ophthalmol. 2002 Feb;133(2):242-8.PMID: 11812429 [PubMed - indexed for MEDLINE]Related articles

Risk factors for metastasis in retinoblastoma.

Finger PT, Harbour JW, Karcioglu ZA.

Surv Ophthalmol. 2002 Jan-Feb;47(1):1-16. Review.PMID: 11801265 [PubMed - indexed for MEDLINE]Related articles