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A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells.
Arden C, Hampson LJ, Huang GC, Shaw JA, Aldibbiat A, Holliman G, Manas D, Khan S, Lange AJ, Agius L.
Biochem J. 2008 Apr 1;411(1):41-51.PMID: 18039179 [PubMed - indexed for MEDLINE]Related articlesFree article
Acetylcholine exerts additive and permissive but not synergistic effects with insulin on glycogen synthesis in hepatocytes.
Hampson LJ, Agius L.
FEBS Lett. 2007 Aug 21;581(21):3955-60. Epub 2007 Jul 23.PMID: 17662981 [PubMed - indexed for MEDLINE]Related articles
Stimulation of glycogen synthesis and inactivation of phosphorylase in hepatocytes by serotonergic mechanisms, and counter-regulation by atypical antipsychotic drugs.
Hampson LJ, Mackin P, Agius L.
Diabetologia. 2007 Aug;50(8):1743-51. Epub 2007 Jun 20.PMID: 17579833 [PubMed - indexed for MEDLINE]Related articles
Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site.
Hampson LJ, Arden C, Agius L, Ganotidis M, Kosmopoulou MN, Tiraidis C, Elemes Y, Sakarellos C, Leonidas DD, Oikonomakos NG.
Bioorg Med Chem. 2006 Dec 1;14(23):7835-45.PMID: 16908161 [PubMed - indexed for MEDLINE]Related articles
Increased sensitivity of glycogen synthesis to phosphorylase-a and impaired expression of the glycogen-targeting protein R6 in hepatocytes from insulin-resistant Zucker fa/fa rats.
Arden C, Green AR, Hampson LJ, Aiston S, Härndahl L, Greenberg CC, Brady MJ, Freeman S, Poucher SM, Agius L.
FEBS J. 2006 May;273(9):1989-99.PMID: 16640562 [PubMed - indexed for MEDLINE]Related articles
The role of protein kinase B/Akt in insulin-induced inactivation of phosphorylase in rat hepatocytes.
Aiston S, Hampson LJ, Arden C, Iynedjian PB, Agius L.
Diabetologia. 2006 Jan;49(1):174-82. Epub 2005 Dec 10.PMID: 16341839 [PubMed - indexed for MEDLINE]Related articles
Increased potency and efficacy of combined phosphorylase inactivation and glucokinase activation in control of hepatocyte glycogen metabolism.
Diabetes. 2005 Mar;54(3):617-23.PMID: 15734835 [PubMed - indexed for MEDLINE]Related articlesFree article
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