PubMed

Signaling Crosstalk during Sequential TLR4 and TLR9 Activation Amplifies the Inflammatory Response of Mouse Macrophages.

De Nardo D, De Nardo CM, Nguyen T, Hamilton JA, Scholz GM.

J Immunol. 2009 Nov 18. [Epub ahead of print]PMID: 19923461 [PubMed - as supplied by publisher]Related articles

The Relationship of Ectopic Lipid Accumulation to Cardiac and Vascular Function in Obesity and Metabolic Syndrome.

Ruberg FL, Chen Z, Hua N, Bigornia S, Guo Z, Hallock K, Jara H, Lavalley M, Phinikaridou A, Qiao Y, Viereck J, Apovian CM, Hamilton JA.

Obesity (Silver Spring). 2009 Oct 29. [Epub ahead of print]PMID: 19875992 [PubMed - as supplied by publisher]Related articles

Fast diffusion of very long chain saturated fatty acids across a bilayer membrane and their rapid extraction by cyclodextrins: implications for adrenoleukodystrophy.

Pillai BK, Jasuja R, Simard JR, Hamilton JA.

J Biol Chem. 2009 Nov 27;284(48):33296-304. Epub 2009 Sep 28.PMID: 19801636 [PubMed - in process]Related articles

Mice Deficient in Phosphofructokinase-M Have Greatly Decreased Fat Stores.

Getty-Kaushik L, Viereck JC, Goodman JM, Guo Z, Lebrasseur NK, Richard AM, Flanagan JN, Yaney GC, Hamilton JA, Tornheim K.

Obesity (Silver Spring). 2009 Sep 24. [Epub ahead of print]PMID: 19779479 [PubMed - as supplied by publisher]Related articles

It's Twitter time.

Hamilton JA.

Hosp Health Netw. 2009 Aug;83(8):6. No abstract available. PMID: 19764357 [PubMed - indexed for MEDLINE]Related articles

Acipimox, an inhibitor of lipolysis, attenuates atherogenesis in LDLR-null mice treated with HIV protease inhibitor ritonavir.

Guo W, Wong S, Pudney J, Jasuja R, Hua N, Jiang L, Miller A, Hruz PW, Hamilton JA, Bhasin S.

Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2028-32. Epub 2009 Sep 17.PMID: 19762785 [PubMed - in process]Related articles

Glucose metabolism is required for oxidized LDL-induced macrophage survival: role of PI3K and Bcl-2 family proteins.

Elsegood CL, Chang M, Jessup W, Scholz GM, Hamilton JA.

Arterioscler Thromb Vasc Biol. 2009 Sep;29(9):1283-9. Epub 2009 Aug 10.PMID: 19667115 [PubMed - indexed for MEDLINE]Related articles

Fatty acids are rapidly delivered to and extracted from membranes by methyl-beta -cyclodextrin.

Brunaldi K, Huang N, Hamilton JA.

J Lipid Res. 2009 Jul 22. [Epub ahead of print]PMID: 19625735 [PubMed - as supplied by publisher]Related articlesFree article

Caveolins sequester fatty acids on the cytoplasmic leaflet of the plasma membrane, augment triglyceride formation and protect cells from lipotoxicity.

Simard JR, Meshulam T, Pillai BK, Kirber MT, Brunaldi K, Xu S, Pilch PF, Hamilton JA.

J Lipid Res. 2009 Jul 15. [Epub ahead of print]PMID: 19605920 [PubMed - as supplied by publisher]Related articlesFree article

Genetic disruption of myostatin reduces the development of proatherogenic dyslipidemia and atherogenic lesions in Ldlr null mice.

Tu P, Bhasin S, Hruz PW, Herbst KL, Castellani LW, Hua N, Hamilton JA, Guo W.

Diabetes. 2009 Aug;58(8):1739-48. Epub 2009 Jun 9.PMID: 19509018 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoxia prolongs monocyte/macrophage survival and enhanced glycolysis is associated with their maturation under aerobic conditions.

Roiniotis J, Dinh H, Masendycz P, Turner A, Elsegood CL, Scholz GM, Hamilton JA.

J Immunol. 2009 Jun 15;182(12):7974-81.PMID: 19494322 [PubMed - indexed for MEDLINE]Related articles

Low dose metal particles can induce monocyte/macrophage survival.

Lacey DC, De Kok B, Clanchy FI, Bailey MJ, Speed K, Haynes D, Graves SE, Hamilton JA.

J Orthop Res. 2009 Nov;27(11):1481-6.PMID: 19459209 [PubMed - indexed for MEDLINE]Related articles

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.

Fleetwood AJ, Dinh H, Cook AD, Hertzog PJ, Hamilton JA.

J Leukoc Biol. 2009 Aug;86(2):411-21. Epub 2009 Apr 30.PMID: 19406830 [PubMed - indexed for MEDLINE]Related articles

The dynamics of macrophage lineage populations in inflammatory and autoimmune diseases.

Hamilton JA, Tak PP.

Arthritis Rheum. 2009 May;60(5):1210-21. Review. No abstract available. PMID: 19404968 [PubMed - indexed for MEDLINE]Related articles

Phosphatidylinostitol-3 kinase and phospholipase C enhance CSF-1-dependent macrophage survival by controlling glucose uptake.

Chang M, Hamilton JA, Scholz GM, Masendycz P, Macaulay SL, Elsegood CL.

Cell Signal. 2009 Sep;21(9):1361-9. Epub 2009 Apr 16.PMID: 19376223 [PubMed - indexed for MEDLINE]Related articles

Early-life sodium exposure unmasks susceptibility to stroke in hyperlipidemic, hypertensive heterozygous Tg25 rats transgenic for human cholesteryl ester transfer protein.

Decano JL, Viereck JC, McKee AC, Hamilton JA, Ruiz-Opazo N, Herrera VL.

Circulation. 2009 Mar 24;119(11):1501-9. Epub 2009 Mar 9.PMID: 19273719 [PubMed - indexed for MEDLINE]Related articles

Glycolytic control of adjuvant-induced macrophage survival: role of PI3K, MEK1/2, and Bcl-2.

Chang M, Hamilton JA, Scholz GM, Elsegood CL.

J Leukoc Biol. 2009 Jun;85(6):947-56. Epub 2009 Mar 6.PMID: 19270084 [PubMed - indexed for MEDLINE]Related articles

The proliferative human monocyte subpopulation contains osteoclast precursors.

Lari R, Kitchener PD, Hamilton JA.

Arthritis Res Ther. 2009;11(1):R23. Epub 2009 Feb 17.PMID: 19222861 [PubMed - indexed for MEDLINE]Related articlesFree article

The generation and properties of human macrophage populations from hemopoietic stem cells.

Way KJ, Dinh H, Keene MR, White KE, Clanchy FI, Lusby P, Roiniotis J, Cook AD, Cassady AI, Curtis DJ, Hamilton JA.

J Leukoc Biol. 2009 May;85(5):766-78. Epub 2009 Jan 30.PMID: 19181863 [PubMed - indexed for MEDLINE]Related articles

Regulation of IRAK-1 activation by its C-terminal domain.

Nguyen T, De Nardo D, Masendycz P, Hamilton JA, Scholz GM.

Cell Signal. 2009 May;21(5):719-26. Epub 2009 Jan 7.PMID: 19166926 [PubMed - indexed for MEDLINE]Related articles

A robust rabbit model of human atherosclerosis and atherothrombosis.

Phinikaridou A, Hallock KJ, Qiao Y, Hamilton JA.

J Lipid Res. 2009 May;50(5):787-97. Epub 2009 Jan 12.PMID: 19141434 [PubMed - indexed for MEDLINE]Related articles

Proinflammatory cytokines inhibit osteogenic differentiation from stem cells: implications for bone repair during inflammation.

Lacey DC, Simmons PJ, Graves SE, Hamilton JA.

Osteoarthritis Cartilage. 2009 Jun;17(6):735-42. Epub 2008 Nov 24.PMID: 19136283 [PubMed - in process]Related articles

Down-regulation of IRAK-4 is a component of LPS- and CpG DNA-induced tolerance in macrophages.

De Nardo D, Nguyen T, Hamilton JA, Scholz GM.

Cell Signal. 2009 Feb;21(2):246-52. Epub 2008 Oct 25.PMID: 18992325 [PubMed - indexed for MEDLINE]Related articles

Revitalizing difference in the HapMap: race and contemporary human genetic variation research.

Hamilton JA.

J Law Med Ethics. 2008 Fall;36(3):471-7.PMID: 18840238 [PubMed - indexed for MEDLINE]Related articles

The role of the RgpA-Kgp proteinase-adhesin complexes in the adherence of Porphyromonas gingivalis to fibroblasts.

Pathirana RD, O'Brien-Simpson NM, Visvanathan K, Hamilton JA, Reynolds EC.

Microbiology. 2008 Oct;154(Pt 10):2904-11.PMID: 18832297 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes.

Gupta V, Bhasin S, Guo W, Singh R, Miki R, Chauhan P, Choong K, Tchkonia T, Lebrasseur NK, Flanagan JN, Hamilton JA, Viereck JC, Narula NS, Kirkland JL, Jasuja R.

Mol Cell Endocrinol. 2008 Dec 16;296(1-2):32-40. Epub 2008 Aug 28.PMID: 18801408 [PubMed - indexed for MEDLINE]Related articles

Regulation of WAVE1 expression in macrophages at multiple levels.

Dinh H, Scholz GM, Hamilton JA.

J Leukoc Biol. 2008 Dec;84(6):1483-91. Epub 2008 Sep 2.PMID: 18765479 [PubMed - indexed for MEDLINE]Related articles

Images in cardiovascular medicine. Healing of an asymptomatic carotid plaque ulceration.

Qiao Y, Farber A, Semaan E, Hamilton JA.

Circulation. 2008 Sep 2;118(10):e147-8. No abstract available. PMID: 18765382 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of the endosomal SNARE protein syntaxin 7 by colony-stimulating factor 1 in macrophages.

Achuthan A, Masendycz P, Lopez JA, Nguyen T, James DE, Sweet MJ, Hamilton JA, Scholz GM.

Mol Cell Biol. 2008 Oct;28(20):6149-59. Epub 2008 Aug 18.PMID: 18710945 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid flip-flop in a model membrane is faster than desorption into the aqueous phase.

Simard JR, Pillai BK, Hamilton JA.

Biochemistry. 2008 Sep 2;47(35):9081-9. Epub 2008 Aug 12.PMID: 18693753 [PubMed - indexed for MEDLINE]Related articles

Colony-stimulating factors in inflammation and autoimmunity.

Hamilton JA.

Nat Rev Immunol. 2008 Jul;8(7):533-44. Review.PMID: 18551128 [PubMed - indexed for MEDLINE]Related articles

The critical role of the colony-stimulating factor-1 receptor in the differentiation of myeloblastic leukemia cells.

Hamilton JA, Whitty G, Masendycz P, Wilson NJ, Jackson J, De Nardo D, Scholz GM.

Mol Cancer Res. 2008 Mar;6(3):458-67.PMID: 18337452 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasminogen activator/plasmin system in arthritis and inflammation: friend or foe?

Hamilton JA.

Arthritis Rheum. 2008 Mar;58(3):645-8. No abstract available. PMID: 18311800 [PubMed - indexed for MEDLINE]Related articlesFree article

Measuring the adsorption of Fatty acids to phospholipid vesicles by multiple fluorescence probes.

Simard JR, Kamp F, Hamilton JA.

Biophys J. 2008 Jun;94(11):4493-503. Epub 2008 Feb 22.PMID: 18296488 [PubMed - indexed for MEDLINE]Related articlesFree article

Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice.

Izumiya Y, Hopkins T, Morris C, Sato K, Zeng L, Viereck J, Hamilton JA, Ouchi N, LeBrasseur NK, Walsh K.

Cell Metab. 2008 Feb;7(2):159-72.PMID: 18249175 [PubMed - indexed for MEDLINE]Related articles

DNA data sharing: research participants' perspectives.

McGuire AL, Hamilton JA, Lunstroth R, McCullough LB, Goldman A.

Genet Med. 2008 Jan;10(1):46-53.PMID: 18197056 [PubMed - indexed for MEDLINE]Related articlesFree article

Importance of the C-terminal domain of Harc for binding to Hsp70 and Hop as well as its response to heat shock.

Cartledge K, Elsegood C, Roiniotis J, Hamilton JA, Scholz GM.

Biochemistry. 2007 Dec 25;46(51):15144-52. Epub 2007 Dec 1.PMID: 18052042 [PubMed - indexed for MEDLINE]Related articles

New insights into the roles of proteins and lipids in membrane transport of fatty acids.

Hamilton JA.

Prostaglandins Leukot Essent Fatty Acids. 2007 Nov-Dec;77(5-6):355-61. Epub 2007 Nov 26. Review.PMID: 18032007 [PubMed - indexed for MEDLINE]Related articles

Fluorescence assays for measuring fatty acid binding and transport through membranes.

Brunaldi K, Simard JR, Kamp F, Rewal C, Asawakarn T, O'Shea P, Hamilton JA.

Methods Mol Biol. 2007;400:237-55. Review.PMID: 17951738 [PubMed - indexed for MEDLINE]Related articles

Acrylodan-labeled intestinal fatty acid-binding protein to measure concentrations of unbound fatty acids.

Simard JR, Kamp F, Hamilton JA.

Methods Mol Biol. 2007;400:27-43. Review.PMID: 17951725 [PubMed - indexed for MEDLINE]Related articles

Brain uptake and utilization of fatty acids, lipids & lipoproteins: recommendations for future research.

Katz R, Hamilton JA, Pownall HJ, Deckelbaum RJ, Hillard CJ, Leboeuf RC, Watkins PA.

J Mol Neurosci. 2007 Sep;33(1):146-50.PMID: 17901559 [PubMed - indexed for MEDLINE]Related articles

Roundtable discussion of session 4: fatty acids and lipids in brain disorders.

Watkins PA, Hamilton JA.

J Mol Neurosci. 2007 Sep;33(1):120-4. No abstract available. PMID: 17901556 [PubMed - indexed for MEDLINE]Related articles

Roundtable discussion of session 3: eicosanoids in brain function.

Watkins PA, Hamilton JA.

J Mol Neurosci. 2007 Sep;33(1):100-4. No abstract available. PMID: 17901553 [PubMed - indexed for MEDLINE]Related articles

Roundtable discussion of session 2: lipoproteins and polyunsaturated fatty acids.

Watkins PA, Hamilton JA.

J Mol Neurosci. 2007 Sep;33(1):74-9. No abstract available. PMID: 17901549 [PubMed - indexed for MEDLINE]Related articles

Roundtable discussion of session 1: mechanisms of lipid uptake and transport in the brain.

Watkins PA, Hamilton JA.

J Mol Neurosci. 2007 Sep;33(1):45-50. No abstract available. PMID: 17901545 [PubMed - indexed for MEDLINE]Related articles

A model for fatty acid transport into the brain.

Hamilton JA, Brunaldi K.

J Mol Neurosci. 2007 Sep;33(1):12-7. Review.PMID: 17901540 [PubMed - indexed for MEDLINE]Related articles

Brain uptake and utilization of fatty acids, lipids and lipoproteins: application to neurological disorders.

Hamilton JA, Hillard CJ, Spector AA, Watkins PA.

J Mol Neurosci. 2007 Sep;33(1):2-11.PMID: 17901539 [PubMed - indexed for MEDLINE]Related articles

Targeted binding of PLA microparticles with lipid-PEG-tethered ligands.

Duncanson WJ, Figa MA, Hallock K, Zalipsky S, Hamilton JA, Wong JY.

Biomaterials. 2007 Nov;28(33):4991-9. Epub 2007 Aug 17.PMID: 17707503 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinaldehyde represses adipogenesis and diet-induced obesity.

Ziouzenkova O, Orasanu G, Sharlach M, Akiyama TE, Berger JP, Viereck J, Hamilton JA, Tang G, Dolnikowski GG, Vogel S, Duester G, Plutzky J.

Nat Med. 2007 Jun;13(6):695-702. Epub 2007 May 27.PMID: 17529981 [PubMed - indexed for MEDLINE]Related articlesFree article

Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.

Sasmono RT, Ehrnsperger A, Cronau SL, Ravasi T, Kandane R, Hickey MJ, Cook AD, Himes SR, Hamilton JA, Hume DA.

J Leukoc Biol. 2007 Jul;82(1):111-23. Epub 2007 Apr 16.PMID: 17438263 [PubMed - indexed for MEDLINE]Related articlesFree article