PubMed

Inhibitors for human glutaminyl cyclase by structure based design and bioisosteric replacement.

Buchholz M, Hamann A, Aust S, Brandt W, Böhme L, Hoffmann T, Schilling S, Demuth HU, Heiser U.

J Med Chem. 2009 Nov 26;52(22):7069-80.PMID: 19863057 [PubMed - in process]Related articles

Priming of CD4(+) T cells by liver sinusoidal endothelial cells induces CD25(low) forkhead box protein 3(-) regulatory T cells suppressing autoimmune hepatitis.

Kruse N, Neumann K, Schrage A, Derkow K, Schott E, Erben U, Kühl A, Loddenkemper C, Zeitz M, Hamann A, Klugewitz K.

Hepatology. 2009 Dec;50(6):1904-13.PMID: 19787806 [PubMed - in process]Related articles

T cells as pioneers: antigen-specific T cells condition inflamed sites for high-rate antigen-non-specific effector cell recruitment.

Ghani S, Feuerer M, Doebis C, Lauer U, Loddenkemper C, Huehn J, Hamann A, Syrbe U.

Immunology. 2009 Sep;128(1 Suppl):e870-80. Epub 2009 Mar 26.PMID: 19740348 [PubMed - in process]Related articles

Establishment of nematode infection despite increased Th2 responses and immunopathology after selective depletion of Foxp3(+) cells.

Rausch S, Huehn J, Loddenkemper C, Hepworth MR, Klotz C, Sparwasser T, Hamann A, Lucius R, Hartmann S.

Eur J Immunol. 2009 Sep 11;39(11):3066-3077. [Epub ahead of print]PMID: 19750483 [PubMed - as supplied by publisher]Related articles

C. elegans as model for the study of high glucose- mediated life span reduction.

Schlotterer A, Kukudov G, Bozorgmehr F, Hutter H, Du X, Oikonomou D, Ibrahim Y, Pfisterer F, Rabbani N, Thornalley P, Sayed A, Fleming T, Humpert P, Schwenger V, Zeier M, Hamann A, Stern D, Brownlee M, Bierhaus A, Nawroth P, Morcos M.

Diabetes. 2009 Nov;58(11):2450-6. Epub 2009 Aug 12.PMID: 19675139 [PubMed - in process]Related articles

[Tissue retention of T cells as a therapeutic target in rheumatoid arthritis]

Syrbe U, Hamann A.

Z Rheumatol. 2009 Oct;68(8):678-82. German. PMID: 19585131 [PubMed - in process]Related articles

CD152 (CTLA-4) determines CD4 T cell migration in vitro and in vivo.

Knieke K, Hoff H, Maszyna F, Kolar P, Schrage A, Hamann A, Debes GF, Brunner-Weinzierl MC.

PLoS One. 2009 May 27;4(5):e5702.PMID: 19479036 [PubMed - indexed for MEDLINE]Related articlesFree article

External electric muscle stimulation improves burning sensations and sleeping disturbances in patients with type 2 diabetes and symptomatic neuropathy.

Humpert PM, Morcos M, Oikonomou D, Schaefer K, Hamann A, Bierhaus A, Schilling T, Nawroth PP.

Pain Med. 2009 Mar;10(2):413-9. Epub 2009 Jan 16.PMID: 19207234 [PubMed - in process]Related articles

Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue.

Wieczorek G, Asemissen A, Model F, Turbachova I, Floess S, Liebenberg V, Baron U, Stauch D, Kotsch K, Pratschke J, Hamann A, Loddenkemper C, Stein H, Volk HD, Hoffmüller U, Grützkau A, Mustea A, Huehn J, Scheibenbogen C, Olek S.

Cancer Res. 2009 Jan 15;69(2):599-608.PMID: 19147574 [PubMed - indexed for MEDLINE]Related articles

The -174G>C IL-6 gene promoter polymorphism and diabetic microvascular complications.

Rudofsky G Jr, Schlotterer A, Reismann P, Engel J, Grafe IA, Tafel J, Morcos M, Humpert PM, Nawroth P, Bierhaus A, Hamann A.

Horm Metab Res. 2009 Apr;41(4):308-13. Epub 2009 Jan 12.PMID: 19140096 [PubMed - indexed for MEDLINE]Related articles

Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?

Huehn J, Polansky JK, Hamann A.

Nat Rev Immunol. 2009 Feb;9(2):83-9.PMID: 19114986 [PubMed - indexed for MEDLINE]Related articles

Cellular players and role of selectin ligands in leukocyte recruitment in a T-cell-initiated delayed-type hypersensitivity reaction.

Doebis C, Siegmund K, Loddenkemper C, Lowe JB, Issekutz AC, Hamann A, Huehn J, Syrbe U.

Am J Pathol. 2008 Oct;173(4):1067-76. Epub 2008 Aug 28.PMID: 18755847 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone reduces angiotensin II and advanced glycation end product-dependent sustained nuclear factor-kappaB activation in cultured human proximal tubular epithelial cells.

Morcos M, Schlotterer A, Sayed AA, Kukudov G, Oikomonou D, Ibrahim Y, Pfisterer F, Schneider J, Bozorgmehr F, Rudofsky G Jr, Schwenger V, Kientsch-Engels R, Hamann A, Zeier M, Dugi K, Yard B, Humpert PM, van der Woude F, Nawroth PP, Bierhaus A.

Horm Metab Res. 2008 Nov;40(11):752-9. Epub 2008 Aug 18.PMID: 18711692 [PubMed - indexed for MEDLINE]Related articles

Enhanced T cell transmigration across the murine liver sinusoidal endothelium is mediated by transcytosis and surface presentation of chemokines.

Schrage A, Wechsung K, Neumann K, Schumann M, Schulzke JD, Engelhardt B, Zeitz M, Hamann A, Klugewitz K.

Hepatology. 2008 Oct;48(4):1262-72.PMID: 18697212 [PubMed - indexed for MEDLINE]Related articles

Autoregulation of Th1-mediated inflammation by twist1.

Niesner U, Albrecht I, Janke M, Doebis C, Loddenkemper C, Lexberg MH, Eulenburg K, Kreher S, Koeck J, Baumgrass R, Bonhagen K, Kamradt T, Enghard P, Humrich JY, Rutz S, Schulze-Topphoff U, Aktas O, Bartfeld S, Radbruch H, Hegazy AN, Löhning M, Baumgart DC, Duchmann R, Rudwaleit M, Häupl T, Gitelman I, Krenn V, Gruen J, Sieper J, Zeitz M, Wiedenmann B, Zipp F, Hamann A, Janitz M, Scheffold A, Burmester GR, Chang HD, Radbruch A.

J Exp Med. 2008 Aug 4;205(8):1889-901. Epub 2008 Jul 28.PMID: 18663125 [PubMed - indexed for MEDLINE]Related articlesFree article

Sustained delayed-type hypersensitivity reaction after in vivo priming but successful induction of unresponsiveness after adoptive transfer of CD4+ effector T cells.

Blumenthal-Barby F, Schrage A, Eulenburg K, Zeitz M, Hamann A, Klugewitz K.

Cell Immunol. 2008 May-Jun;253(1-2):110-5. Epub 2008 Jul 1.PMID: 18597746 [PubMed - indexed for MEDLINE]Related articles

DNA methylation controls Foxp3 gene expression.

Polansky JK, Kretschmer K, Freyer J, Floess S, Garbe A, Baron U, Olek S, Hamann A, von Boehmer H, Huehn J.

Eur J Immunol. 2008 Jun;38(6):1654-63.PMID: 18493985 [PubMed - indexed for MEDLINE]Related articles

In vivo modulation of antigen-experienced cells in response to high-dose oral antigen: deletion but no evidence for alterations in the cytokine phenotype.

Blumenthal-Barby F, Eulenburg K, Schrage A, Zeitz M, Hamann A, Klugewitz K.

Int Immunol. 2008 Jul;20(7):893-900. Epub 2008 May 19.PMID: 18492659 [PubMed - indexed for MEDLINE]Related articles

[Necrotizing fasciitis caused by group G streptococci]

Horas U, Herbst U, Hamann A, Ernst S.

Orthopade. 2008 Jun;37(6):592-4. German. PMID: 18461304 [PubMed - indexed for MEDLINE]Related articles

Apoptosis pathways in fungal growth, development and ageing.

Hamann A, Brust D, Osiewacz HD.

Trends Microbiol. 2008 Jun;16(6):276-83. Epub 2008 Apr 25. Review.PMID: 18440231 [PubMed - indexed for MEDLINE]Related articles

Atherogenic dyslipidaemia but not total- and high-molecular weight adiponectin are associated with the prognostic outcome in patients with coronary heart disease.

von Eynatten M, Hamann A, Twardella D, Nawroth PP, Brenner H, Rothenbacher D.

Eur Heart J. 2008 May;29(10):1307-15. Epub 2008 Apr 5.PMID: 18390868 [PubMed - indexed for MEDLINE]Related articlesFree article

A helminth immunomodulator reduces allergic and inflammatory responses by induction of IL-10-producing macrophages.

Schnoeller C, Rausch S, Pillai S, Avagyan A, Wittig BM, Loddenkemper C, Hamann A, Hamelmann E, Lucius R, Hartmann S.

J Immunol. 2008 Mar 15;180(6):4265-72.PMID: 18322239 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional analysis of effector and regulatory T cells in a parasitic nematode infection.

Rausch S, Huehn J, Kirchhoff D, Rzepecka J, Schnoeller C, Pillai S, Loddenkemper C, Scheffold A, Hamann A, Lucius R, Hartmann S.

Infect Immun. 2008 May;76(5):1908-19. Epub 2008 Mar 3.PMID: 18316386 [PubMed - indexed for MEDLINE]Related articlesFree article

Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans.

Morcos M, Du X, Pfisterer F, Hutter H, Sayed AA, Thornalley P, Ahmed N, Baynes J, Thorpe S, Kukudov G, Schlotterer A, Bozorgmehr F, El Baki RA, Stern D, Moehrlen F, Ibrahim Y, Oikonomou D, Hamann A, Becker C, Zeier M, Schwenger V, Miftari N, Humpert P, Hammes HP, Buechler M, Bierhaus A, Brownlee M, Nawroth PP.

Aging Cell. 2008 Mar;7(2):260-9. Epub 2008 Jan 21.PMID: 18221415 [PubMed - indexed for MEDLINE]Related articles

Murine CD146 is widely expressed on endothelial cells and is recognized by the monoclonal antibody ME-9F1.

Schrage A, Loddenkemper C, Erben U, Lauer U, Hausdorf G, Jungblut PR, Johnson J, Knolle PA, Zeitz M, Hamann A, Klugewitz K.

Histochem Cell Biol. 2008 Apr;129(4):441-51. Epub 2008 Jan 24.PMID: 18214516 [PubMed - indexed for MEDLINE]Related articlesFree article

Potential benefits of early addition of rosiglitazone in combination with glimepiride in the treatment of type 2 diabetes.

Rosenstock J, Chou HS, Matthaei S, Seidel DK, Hamann A.

Diabetes Obes Metab. 2008 Sep;10(10):862-73. Epub 2008 Jan 14.PMID: 18201206 [PubMed - indexed for MEDLINE]Related articles

Experience-driven development: effector/memory-like alphaE+Foxp3+ regulatory T cells originate from both naive T cells and naturally occurring naive-like regulatory T cells.

Siewert C, Lauer U, Cording S, Bopp T, Schmitt E, Hamann A, Huehn J.

J Immunol. 2008 Jan 1;180(1):146-55.PMID: 18097014 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of fixed-dose rosiglitazone/metformin combination therapy with sulphonylurea plus metformin in overweight individuals with Type 2 diabetes inadequately controlled on metformin alone.

Hamann A, Garcia-Puig J, Paul G, Donaldson J, Stewart M.

Exp Clin Endocrinol Diabetes. 2008 Jan;116(1):6-13. Epub 2007 Dec 20.PMID: 18095238 [PubMed - indexed for MEDLINE]Related articles

[Pharmacotherapy of obesity]

Hamann A.

Internist (Berl). 2008 Jan;49(1):106-13. Review. German. PMID: 18060334 [PubMed - indexed for MEDLINE]Related articles

High-molecular weight adiponectin is independently associated with the extent of coronary artery disease in men.

von Eynatten M, Humpert PM, Bluemm A, Lepper PM, Hamann A, Allolio B, Nawroth PP, Bierhaus A, Dugi KA.

Atherosclerosis. 2008 Jul;199(1):123-8. Epub 2007 Nov 19.PMID: 18021784 [PubMed - indexed for MEDLINE]Related articles

Superconductivity on the border of weak itinerant ferromagnetism in UCoGe.

Huy NT, Gasparini A, de Nijs DE, Huang Y, Klaasse JC, Gortenmulder T, de Visser A, Hamann A, Görlach T, Löhneysen HV.

Phys Rev Lett. 2007 Aug 10;99(6):067006. Epub 2007 Aug 10.PMID: 17930860 [PubMed]Related articles

A M55V polymorphism in the SUMO4 gene is associated with a reduced prevalence of diabetic retinopathy in patients with Type 1 diabetes.

Rudofsky G Jr, Schlotterer A, Humpert PM, Tafel J, Morcos M, Nawroth PP, Bierhaus A, Hamann A.

Exp Clin Endocrinol Diabetes. 2008 Jan;116(1):14-7. Epub 2007 Oct 9.PMID: 17926234 [PubMed - indexed for MEDLINE]Related articles

Improved vascular function upon pioglitazone treatment in type 2 diabetes is not associated with changes in mononuclear NF-kappaB binding activity.

Rudofsky G Jr, Reismann P, Grafe IA, Konrade I, Djuric Z, Tafel J, Buchbinder S, Zorn M, Humpert PM, Hamann A, Morcos M, Nawroth PP, Bierhaus A.

Horm Metab Res. 2007 Sep;39(9):665-71.PMID: 17846974 [PubMed - indexed for MEDLINE]Related articles

DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells.

Baron U, Floess S, Wieczorek G, Baumann K, Grützkau A, Dong J, Thiel A, Boeld TJ, Hoffmann P, Edinger M, Türbachova I, Hamann A, Olek S, Huehn J.

Eur J Immunol. 2007 Sep;37(9):2378-89.PMID: 17694575 [PubMed - indexed for MEDLINE]Related articles

Comment on: Lin et al. (2007) SUMO4 M55V variant is associated with diabetic nephropathy in type 2 diabetes: Diabetes 56: 1177-1180.

Rudofsky G Jr, Schlotterer A, Nawroth PP, Bierhaus A, Hamann A.

Diabetes. 2007 Aug;56(8):e11; author reply e12-3. No abstract available. PMID: 17660269 [PubMed - indexed for MEDLINE]Related articlesFree article

Deletion of putative apoptosis factors leads to lifespan extension in the fungal ageing model Podospora anserina.

Hamann A, Brust D, Osiewacz HD.

Mol Microbiol. 2007 Aug;65(4):948-58. Epub 2007 Jul 11.PMID: 17627766 [PubMed - indexed for MEDLINE]Related articles

Long-term commitment to inflammation-seeking homing in CD4+ effector cells.

Jennrich S, Ratsch BA, Hamann A, Syrbe U.

J Immunol. 2007 Jun 15;178(12):8073-80.PMID: 17548645 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term treatment of central Cushing's syndrome with rosiglitazone.

Morcos M, Fohr B, Tafel J, Pfisterer F, Hamann A, Humpert P, Bode H, Schwenger V, Zeier M, Becker C, Kasperk C, Schilling T, Hammes HP, Bierhaus A, Nawroth PP.

Exp Clin Endocrinol Diabetes. 2007 May;115(5):292-7.PMID: 17516291 [PubMed - indexed for MEDLINE]Related articles

Levels of three distinct p75 neurotrophin receptor forms found in human plasma are altered in type 2 diabetic patients.

Humpert PM, Kopf S, Djuric Z, Laine K, Korosoglou G, Rudofsky G Jr, Hamann A, Morcos M, von Eynatten M, Nawroth PP, Bierhaus A.

Diabetologia. 2007 Jul;50(7):1517-22. Epub 2007 May 11.PMID: 17492429 [PubMed - indexed for MEDLINE]Related articles

[Diabetes caught in the middle between science, guidelines and the (German) Institute for Quality and Efficiency in Health Care (IQWiG)]

Hamann A, Hammes HP, Nawroth P.

Dtsch Med Wochenschr. 2007 May 11;132(19):1062-4. German. No abstract available. PMID: 17476639 [PubMed - indexed for MEDLINE]Related articles

[Adipokines and lipid metabolism in type 2 diabetes]

von Eynatten M, Hamann A.

Dtsch Med Wochenschr. 2007 May 11;132(19):1048-52. Review. German. No abstract available. PMID: 17476636 [PubMed - indexed for MEDLINE]Related articles

Distinctive role of CCR7 in migration and functional activity of naive- and effector/memory-like Treg subsets.

Menning A, Höpken UE, Siegmund K, Lipp M, Hamann A, Huehn J.

Eur J Immunol. 2007 Jun;37(6):1575-83.PMID: 17474155 [PubMed - indexed for MEDLINE]Related articles

Promoter polymorphisms of UCP1, UCP2, and UCP3 are not associated with diabetic microvascular complications in type 2 diabetes.

Rudofsky G Jr, Schrödter A, Voron'ko OE, Schlotterer A, Humpert PM, Tafel J, Nawroth PP, Bierhaus A, Hamann A.

Horm Metab Res. 2007 Apr;39(4):306-9. No abstract available. PMID: 17447170 [PubMed - indexed for MEDLINE]Related articles

Induction of organ-selective CD4+ regulatory T cell homing.

Siewert C, Menning A, Dudda J, Siegmund K, Lauer U, Floess S, Campbell DJ, Hamann A, Huehn J.

Eur J Immunol. 2007 Apr;37(4):978-89.PMID: 17345581 [PubMed - indexed for MEDLINE]Related articles

Epigenetic control of the foxp3 locus in regulatory T cells.

Floess S, Freyer J, Siewert C, Baron U, Olek S, Polansky J, Schlawe K, Chang HD, Bopp T, Schmitt E, Klein-Hessling S, Serfling E, Hamann A, Huehn J.

PLoS Biol. 2007 Feb;5(2):e38.PMID: 17298177 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease.

Lahl K, Loddenkemper C, Drouin C, Freyer J, Arnason J, Eberl G, Hamann A, Wagner H, Huehn J, Sparwasser T.

J Exp Med. 2007 Jan 22;204(1):57-63. Epub 2007 Jan 2.PMID: 17200412 [PubMed - indexed for MEDLINE]Related articlesFree article

Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models.

Scheckhuber CQ, Erjavec N, Tinazli A, Hamann A, Nyström T, Osiewacz HD.

Nat Cell Biol. 2007 Jan;9(1):99-105. Epub 2006 Dec 7.PMID: 17173038 [PubMed - indexed for MEDLINE]Related articles

Potential effects of climate change on ecosystem and tree species distribution in British Columbia.

Hamann A, Wang T.

Ecology. 2006 Nov;87(11):2773-86.PMID: 17168022 [PubMed - indexed for MEDLINE]Related articles

[Development of body weight during antidiabetic treatment]

Hamann A.

Dtsch Med Wochenschr. 2006 Dec;131 Suppl 8:S255-8. Review. German. PMID: 17139582 [PubMed - indexed for MEDLINE]Related articles

Microenvironment-dependent requirement of STAT4 for the induction of P-selectin ligands and effector cytokines on CD4+ T cells in healthy and parasite-infected mice.

Syrbe U, Hoffmann U, Schlawe K, Liesenfeld O, Erb K, Hamann A.

J Immunol. 2006 Dec 1;177(11):7673-9.PMID: 17114437 [PubMed - indexed for MEDLINE]Related articlesFree article