PubMed

Glycated-CD59 antigen: exploration of synthetic approaches.

Cantel S, Kavishwar A, Schlimme M, Khatri A, Halperin JA, Chorev M.

Adv Exp Med Biol. 2009;611:317-8. No abstract available. PMID: 19400208 [PubMed - indexed for MEDLINE]Related articles

Side chain-to-side chain cyclization by intramolecular click reaction--building blocks, solid phase synthesis and conformational characterization.

Cantel S, Halperin JA, Chorev M, Scrima M, D'Ursi AM, Levy JJ, DiMarchi RD, Le Chevalier A, Rovero P, Papini AM.

Adv Exp Med Biol. 2009;611:175-6. No abstract available. PMID: 19400147 [PubMed - indexed for MEDLINE]Related articles

Balancing role of nitric oxide in complement-mediated activation of platelets from mCd59a and mCd59b double-knockout mice.

Qin X, Hu W, Song W, Blair P, Wu G, Hu X, Song Y, Bauer S, Feelisch M, Leopold JA, Loscalzo J, Halperin JA.

Am J Hematol. 2009 Apr;84(4):221-7.PMID: 19229985 [PubMed - indexed for MEDLINE]Related articles

Complement regulator CD59 protects against atherosclerosis by restricting the formation of complement membrane attack complex.

Wu G, Hu W, Shahsafaei A, Song W, Dobarro M, Sukhova GK, Bronson RR, Shi GP, Rother RP, Halperin JA, Qin X.

Circ Res. 2009 Feb 27;104(4):550-8. Epub 2009 Jan 8.PMID: 19131645 [PubMed - indexed for MEDLINE]Related articles

Building blocks for the synthesis of post-translationally modified glycated peptides and proteins.

Carganico S, Rovero P, Halperin JA, Papini AM, Chorev M.

J Pept Sci. 2009 Feb;15(2):67-71.PMID: 19090529 [PubMed - indexed for MEDLINE]Related articles

Generation and phenotyping of mCd59a and mCd59b double-knockout mice.

Qin X, Hu W, Song W, Grubissich L, Hu X, Wu G, Ferris S, Dobarro M, Halperin JA.

Am J Hematol. 2009 Feb;84(2):65-70.PMID: 19051264 [PubMed - indexed for MEDLINE]Related articles

Synthesis and conformational analysis of a cyclic peptide obtained via i to i+4 intramolecular side-chain to side-chain azide-alkyne 1,3-dipolar cycloaddition.

Cantel S, Isaad Ale C, Scrima M, Levy JJ, DiMarchi RD, Rovero P, Halperin JA, D'Ursi AM, Papini AM, Chorev M.

J Org Chem. 2008 Aug 1;73(15):5663-74. Epub 2008 May 20.PMID: 18489158 [PubMed - indexed for MEDLINE]Related articles

Rapid conditional targeted ablation of cells expressing human CD59 in transgenic mice by intermedilysin.

Hu W, Ferris SP, Tweten RK, Wu G, Radaeva S, Gao B, Bronson RT, Halperin JA, Qin X.

Nat Med. 2008 Jan;14(1):98-103. Epub 2007 Dec 23.PMID: 18157141 [PubMed - indexed for MEDLINE]Related articles

Ultrahigh-resolution (1)H-(13)C HSQC spectra of metabolite mixtures using nonlinear sampling and forward maximum entropy reconstruction.

Hyberts SG, Heffron GJ, Tarragona NG, Solanky K, Edmonds KA, Luithardt H, Fejzo J, Chorev M, Aktas H, Colson K, Falchuk KH, Halperin JA, Wagner G.

J Am Chem Soc. 2007 Apr 25;129(16):5108-16. Epub 2007 Mar 28.PMID: 17388596 [PubMed - indexed for MEDLINE]Related articlesFree article

Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G.

Moerke NJ, Aktas H, Chen H, Cantel S, Reibarkh MY, Fahmy A, Gross JD, Degterev A, Yuan J, Chorev M, Halperin JA, Wagner G.

Cell. 2007 Jan 26;128(2):257-67.PMID: 17254965 [PubMed - indexed for MEDLINE]Related articles

Analysis of the promoters and 5'-UTR of mouse Cd59 genes, and of their functional activity in erythrocytes.

Qin X, Ferris S, Hu W, Guo F, Ziegeler G, Halperin JA.

Genes Immun. 2006 Jun;7(4):287-97. Epub 2006 Mar 16.PMID: 16541098 [PubMed - indexed for MEDLINE]Related articles

Further characterization of reproductive abnormalities in mCd59b knockout mice: a potential new function of mCd59 in male reproduction.

Qin X, Dobarro M, Bedford SJ, Ferris S, Miranda PV, Song W, Bronson RT, Visconti PE, Halperin JA.

J Immunol. 2005 Nov 15;175(10):6294-302.PMID: 16272280 [PubMed - indexed for MEDLINE]Related articlesFree article

Synthetic studies toward aryl-(4-aryl-4H-[1,2,4]triazole-3-yl)-amine from 1,3-diarylthiourea as urea mimetics.

Natarajan A, Guo Y, Arthanari H, Wagner G, Halperin JA, Chorev M.

J Org Chem. 2005 Aug 5;70(16):6362-8.PMID: 16050698 [PubMed - indexed for MEDLINE]Related articles

Novel arylsulfoanilide-oxindole hybrid as an anticancer agent that inhibits translation initiation.

Natarajan A, Guo Y, Harbinski F, Fan YH, Chen H, Luus L, Diercks J, Aktas H, Chorev M, Halperin JA.

J Med Chem. 2004 Oct 7;47(21):4979-82.PMID: 15456240 [PubMed - indexed for MEDLINE]Related articles

Synthesis and biological evaluation of thiazolidine-2,4-dione and 2,4-thione derivatives as inhibitors of translation initiation.

Chen H, Fan YH, Natarajan A, Guo Y, Iyasere J, Harbinski F, Luus L, Christ W, Aktas H, Halperin JA.

Bioorg Med Chem Lett. 2004 Nov 1;14(21):5401-5.PMID: 15454234 [PubMed - indexed for MEDLINE]Related articles

Glycation inactivation of the complement regulatory protein CD59: a possible role in the pathogenesis of the vascular complications of human diabetes.

Qin X, Goldfine A, Krumrei N, Grubissich L, Acosta J, Chorev M, Hays AP, Halperin JA.

Diabetes. 2004 Oct;53(10):2653-61.PMID: 15448097 [PubMed - indexed for MEDLINE]Related articlesFree article

Translational regulation of gene expression by omega-3 fatty acids.

Aktas H, Halperin JA.

J Nutr. 2004 Sep;134(9):2487S-2491S. Review.PMID: 15333747 [PubMed - indexed for MEDLINE]Related articlesFree article

Synthesis of fluorescein labeled 7-methylguanosinemonophosphate.

Natarajan A, Moerke N, Fan YH, Chen H, Christ WJ, Wagner G, Halperin JA.

Bioorg Med Chem Lett. 2004 May 17;14(10):2657-60.PMID: 15109672 [PubMed - indexed for MEDLINE]Related articles

Structure-activity requirements for the antiproliferative effect of troglitazone derivatives mediated by depletion of intracellular calcium.

Fan YH, Chen H, Natarajan A, Guo Y, Harbinski F, Iyasere J, Christ W, Aktas H, Halperin JA.

Bioorg Med Chem Lett. 2004 May 17;14(10):2547-50.PMID: 15109648 [PubMed - indexed for MEDLINE]Related articles

3,3-diaryl-1,3-dihydroindol-2-ones as antiproliferatives mediated by translation initiation inhibition.

Natarajan A, Fan YH, Chen H, Guo Y, Iyasere J, Harbinski F, Christ WJ, Aktas H, Halperin JA.

J Med Chem. 2004 Apr 8;47(8):1882-5.PMID: 15055987 [PubMed - indexed for MEDLINE]Related articles

Deficiency of the mouse complement regulatory protein mCd59b results in spontaneous hemolytic anemia with platelet activation and progressive male infertility.

Qin X, Krumrei N, Grubissich L, Dobarro M, Aktas H, Perez G, Halperin JA.

Immunity. 2003 Feb;18(2):217-27.PMID: 12594949 [PubMed - indexed for MEDLINE]Related articles

A possible role for complement in the pathogenesis of chronic chagasic cardiomyopathy.

Aiello VD, Reis MM, Benvenuti LA, Higuchi Mde L, Ramires JA, Halperin JA.

J Pathol. 2002 Jun;197(2):224-9.PMID: 12015747 [PubMed - indexed for MEDLINE]Related articles

Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor gamma and mediated by inhibition of translation initiation.

Palakurthi SS, Aktas H, Grubissich LM, Mortensen RM, Halperin JA.

Cancer Res. 2001 Aug 15;61(16):6213-8.PMID: 11507074 [PubMed - indexed for MEDLINE]Related articlesFree article

Genomic structure, functional comparison, and tissue distribution of mouse Cd59a and Cd59b.

Qin X, Miwa T, Aktas H, Gao M, Lee C, Qian YM, Morton CC, Shahsafaei A, Song WC, Halperin JA.

Mamm Genome. 2001 Aug;12(8):582-9.PMID: 11471050 [PubMed - indexed for MEDLINE]Related articles

Identification and functional characterization of a new gene encoding the mouse terminal complement inhibitor CD59.

Qian YM, Qin X, Miwa T, Sun X, Halperin JA, Song WC.

J Immunol. 2000 Sep 1;165(5):2528-34.PMID: 10946279 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of translation initiation mediates the anticancer effect of the n-3 polyunsaturated fatty acid eicosapentaenoic acid.

Palakurthi SS, Flückiger R, Aktas H, Changolkar AK, Shahsafaei A, Harneit S, Kilic E, Halperin JA.

Cancer Res. 2000 Jun 1;60(11):2919-25.PMID: 10850438 [PubMed - indexed for MEDLINE]Related articlesFree article

Setting health standards for the 21st century.

Halperin JA.

J Am Pharm Assoc (Wash). 1998 Nov-Dec;38(6):762-6.PMID: 9861795 [PubMed - indexed for MEDLINE]Related articles

Depletion of intracellular Ca2+ stores, phosphorylation of eIF2alpha, and sustained inhibition of translation initiation mediate the anticancer effects of clotrimazole.

Aktas H, Flückiger R, Acosta JA, Savage JM, Palakurthi SS, Halperin JA.

Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8280-5.PMID: 9653178 [PubMed - indexed for MEDLINE]Related articlesFree article

Useful patient information on prescription drugs.

Halperin JA.

Ann Pharmacother. 1998 May;32(5):612. No abstract available. PMID: 9606488 [PubMed - indexed for MEDLINE]Related articles

Characterization of neuronal cell death induced by complement activation.

Shen Y, Halperin JA, Benzaquen L, Lee CM.

Brain Res Brain Res Protoc. 1997 May;1(2):186-94.PMID: 9385083 [PubMed - indexed for MEDLINE]Related articles

The transient pore formed by homologous terminal complement complexes functions as a bidirectional route for the transport of autocrine and paracrine signals across human cell membranes.

Acosta JA, Benzaquen LR, Goldstein DJ, Tosteson MT, Halperin JA.

Mol Med. 1996 Nov;2(6):755-65.PMID: 8972490 [PubMed - indexed for MEDLINE]Related articlesFree article

Medicine, pharmacy, and industry--a fly's eye view of health care.

Halperin JA.

Ann Pharmacother. 1995 Sep;29(9):925-33. No abstract available. PMID: 8547743 [PubMed - indexed for MEDLINE]Related articles

Clotrimazole inhibits cell proliferation in vitro and in vivo.

Benzaquen LR, Brugnara C, Byers HR, Gatton-Celli S, Halperin JA.

Nat Med. 1995 Jun;1(6):534-40. Erratum in: Nat Med 1995 Jul;1(7):717. PMID: 7585119 [PubMed - indexed for MEDLINE]Related articles

Complement-mediated neurotoxicity is regulated by homologous restriction.

Shen Y, Halperin JA, Lee CM.

Brain Res. 1995 Feb 13;671(2):282-92.PMID: 7743216 [PubMed - indexed for MEDLINE]Related articles

Terminal complement proteins C5b-9 release basic fibroblast growth factor and platelet-derived growth factor from endothelial cells.

Benzaquen LR, Nicholson-Weller A, Halperin JA.

J Exp Med. 1994 Mar 1;179(3):985-92.PMID: 8113689 [PubMed - indexed for MEDLINE]Related articlesFree article

Activated complement directly modifies the performance of isolated heart muscle cells from guinea pig and rat.

Berger HJ, Taratuska A, Smith TW, Halperin JA.

Am J Physiol. 1993 Jul;265(1 Pt 2):H267-72.PMID: 8342642 [PubMed - indexed for MEDLINE]Related articles

Terminal complement complex C5b-9 stimulates mitogenesis in 3T3 cells.

Halperin JA, Taratuska A, Nicholson-Weller A.

J Clin Invest. 1993 May;91(5):1974-8.PMID: 8486768 [PubMed - indexed for MEDLINE]Related articlesFree article

Membrane signaling by complement C5b-9, the membrane attack complex.

Nicholson-Weller A, Halperin JA.

Immunol Res. 1993;12(3):244-57. Review.PMID: 8288945 [PubMed - indexed for MEDLINE]Related articles

Transient changes in erythrocyte membrane permeability are induced by sublytic amounts of the complement membrane attack complex (C5b-9).

Halperin JA, Taratuska A, Rynkiewicz M, Nicholson-Weller A.

Blood. 1993 Jan 1;81(1):200-5.PMID: 7678066 [PubMed - indexed for MEDLINE]Related articlesFree article

A voltage-activated cation transport pathway associated with the sodium pump.

Halperin JA, Cornelius F.

Biochim Biophys Acta. 1991 Dec 9;1070(2):497-500.PMID: 1662540 [PubMed - indexed for MEDLINE]Related articles

Palytoxin induces an increase in the cation conductance of red cells.

Tosteson MT, Halperin JA, Kishi Y, Tosteson DC.

J Gen Physiol. 1991 Nov;98(5):969-85.PMID: 1684984 [PubMed - indexed for MEDLINE]Related articlesFree article

Request that the USP Committee of Revision reevaluate its position relative to the inclusion of clean room air and microbial limits in the U.S. Pharmacopeia (USP)

Halperin JA.

J Parenter Sci Technol. 1991 Jul-Aug;45(4):168. No abstract available. PMID: 1770407 [PubMed - indexed for MEDLINE]Related articles

Voltage-activated cation permeability in high-potassium but not low-potassium red blood cells.

Halperin JA, Brugnara C, Van Ha T, Tosteson DC.

Am J Physiol. 1990 Jun;258(6 Pt 1):C1169-72.PMID: 1694398 [PubMed - indexed for MEDLINE]Related articles

Suppression of cerebrospinal fluid (CSF) production by a Na+/K+ pump inhibitor extracted from human cerebrospinal fluid.

Lorenzo AV, Taratuska A, Halperin JA.

Z Kinderchir. 1989 Dec;44 Suppl 1:24-6.PMID: 2560297 [PubMed - indexed for MEDLINE]Related articles

Voltage-activated cation transport in human erythrocytes.

Halperin JA, Brugnara C, Tosteson MT, Van Ha T, Tosteson DC.

Am J Physiol. 1989 Nov;257(5 Pt 1):C986-96.PMID: 2596592 [PubMed - indexed for MEDLINE]Related articles

Ca2+-activated K+ efflux limits complement-mediated lysis of human erythrocytes.

Halperin JA, Brugnara C, Nicholson-Weller A.

J Clin Invest. 1989 May;83(5):1466-71.PMID: 2708520 [PubMed - indexed for MEDLINE]Related articlesFree article

Potassium iodide as a thyroid blocker--Three Mile Island to today.

Halperin JA.

DICP. 1989 May;23(5):422-7.PMID: 2471366 [PubMed - indexed for MEDLINE]Related articles

Digitalis-like properties of an inhibitor of the Na+/K+ pump in human cerebrospinal fluid.

Halperin JA.

J Neurol Sci. 1989 Apr;90(2):217-30.PMID: 2542468 [PubMed - indexed for MEDLINE]Related articles

Paroxysmal nocturnal hemoglobinuria. A complement-mediated disease.

Halperin JA, Nicholson-Weller A.

Complement Inflamm. 1989;6(1):65-72. Review.PMID: 2650991 [PubMed - indexed for MEDLINE]Related articles

Mechanisms by which the erythrocyte protects itself from complement damage.

Nicholson-Weller A, Halperin JA.

Prog Clin Biol Res. 1989;297:263-70; discussion 270-1. No abstract available. PMID: 2479950 [PubMed - indexed for MEDLINE]Related articles