PubMed

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, Zhang H, Frackelton EC, Hou C, Flory JH, Otieno G, Chiavacci RM, Grundmeier R, Castro M, Latiano A, Dallapiccola B, Stempak J, Abrams DJ, Taylor K, McGovern D; Western Regional Research Alliance for Pediatric IBD; International IBD Genetics Consortium, Heyman MB, Ferry GD, Kirschner B, Lee J, Essers J, Grand R, Stephens M, Levine A, Piccoli D, Van Limbergen J, Cucchiara S, Monos DS, Guthery SL, Denson L, Wilson DC, Grant SF, Daly M, Silverberg MS, Satsangi J, Hakonarson H.

Nat Genet. 2009 Nov 15. [Epub ahead of print]PMID: 19915574 [PubMed - as supplied by publisher]Related articles

A genome-wide association study on African-ancestry populations for asthma.

Mathias RA, Grant AV, Rafaels N, Hand T, Gao L, Vergara C, Tsai YJ, Yang M, Campbell M, Foster C, Gao P, Togias A, Hansel NN, Diette G, Adkinson NF, Liu MC, Faruque M, Dunston GM, Watson HR, Bracken MB, Hoh J, Maul P, Maul T, Jedlicka AE, Murray T, Hetmanski JB, Ashworth R, Ongaco CM, Hetrick KN, Doheny KF, Pugh EW, Rotimi CN, Ford J, Eng C, Burchard EG, Sleiman PM, Hakonarson H, Forno E, Raby BA, Weiss ST, Scott AF, Kabesch M, Liang L, Abecasis G, Moffatt MF, Cookson WO, Ruczinski I, Beaty TH, Barnes KC.

J Allergy Clin Immunol. 2009 Nov 10. [Epub ahead of print]PMID: 19910028 [PubMed - as supplied by publisher]Related articles

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.

Soranzo N, Spector TD, Mangino M, Kühnel B, Rendon A, Teumer A, Willenborg C, Wright B, Chen L, Li M, Salo P, Voight BF, Burns P, Laskowski RA, Xue Y, Menzel S, Altshuler D, Bradley JR, Bumpstead S, Burnett MS, Devaney J, Döring A, Elosua R, Epstein SE, Erber W, Falchi M, Garner SF, Ghori MJ, Goodall AH, Gwilliam R, Hakonarson HH, Hall AS, Hammond N, Hengstenberg C, Illig T, König IR, Knouff CW, McPherson R, Melander O, Mooser V, Nauck M, Nieminen MS, O'Donnell CJ, Peltonen L, Potter SC, Prokisch H, Rader DJ, Rice CM, Roberts R, Salomaa V, Sambrook J, Schreiber S, Schunkert H, Schwartz SM, Serbanovic-Canic J, Sinisalo J, Siscovick DS, Stark K, Surakka I, Stephens J, Thompson JR, Völker U, Völzke H, Watkins NA, Wells GA, Wichmann HE, Van Heel DA, Tyler-Smith C, Thein SL, Kathiresan S, Perola M, Reilly MP, Stewart AF, Erdmann J, Samani NJ, Meisinger C, Greinacher A, Deloukas P, Ouwehand WH, Gieger C.

Nat Genet. 2009 Nov;41(11):1182-90. Epub 2009 Oct 11.PMID: 19820697 [PubMed - in process]Related articles

From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes.

Wei Z, Wang K, Qu HQ, Zhang H, Bradfield J, Kim C, Frackleton E, Hou C, Glessner JT, Chiavacci R, Stanley C, Monos D, Grant SF, Polychronakos C, Hakonarson H.

PLoS Genet. 2009 Oct;5(10):e1000678. Epub 2009 Oct 9.PMID: 19816555 [PubMed - in process]Related articlesFree article

A cis-acting regulatory variant in the IL2RA locus.

Qu HQ, Verlaan DJ, Ge B, Lu Y, Lam KC, Grabs R, Harmsen E, Hudson TJ, Hakonarson H, Pastinen T, Polychronakos C.

J Immunol. 2009 Oct 15;183(8):5158-62. Epub 2009 Sep 30.PMID: 19794070 [PubMed - indexed for MEDLINE]Related articles

Genetic determinants of pediatric inflammatory bowel disease: is age of onset genetically determined?

Scherr R, Essers J, Hakonarson H, Kugathasan S.

Dig Dis. 2009;27(3):236-9. Epub 2009 Sep 24.PMID: 19786746 [PubMed - in process]Related articles

Common variants in polygenic schizophrenia.

Glessner JT, Hakonarson H.

Genome Biol. 2009;10(9):236. Epub 2009 Sep 29.PMID: 19785721 [PubMed - in process]Related articles

17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry.

Flory JH, Sleiman PM, Christie JD, Annaiah K, Bradfield J, Kim CE, Glessner J, Imielinski M, Li H, Frackelton EC, Cuiping H, Otieno G, Thomas K, Smith R, Glaberson W, Garris M, Chiavacci R, Allen J, Spergel J, Grundmeier R, Grunstein M, Magnusson M, Grant SF, Bønnelykke K, Bisgaard H, Hakonarson H.

J Allergy Clin Immunol. 2009 Sep;124(3):605-7. Epub 2009 Aug 5. No abstract available. PMID: 19660801 [PubMed - indexed for MEDLINE]Related articles

A genome-wide association study identifies a locus for nonsyndromic cleft lip with or without cleft palate on 8q24.

Grant SF, Wang K, Zhang H, Glaberson W, Annaiah K, Kim CE, Bradfield JP, Glessner JT, Thomas KA, Garris M, Frackelton EC, Otieno FG, Chiavacci RM, Nah HD, Kirschner RE, Hakonarson H.

J Pediatr. 2009 Dec;155(6):909-13. Epub 2009 Aug 4.PMID: 19656524 [PubMed - in process]Related articles

Multiple testing in genome-wide association studies via hidden Markov models.

Wei Z, Sun W, Wang K, Hakonarson H.

Bioinformatics. 2009 Nov 1;25(21):2802-8. Epub 2009 Aug 4.PMID: 19654115 [PubMed - in process]Related articles

High-resolution mapping and analysis of copy number variations in the human genome: a data resource for clinical and research applications.

Shaikh TH, Gai X, Perin JC, Glessner JT, Xie H, Murphy K, O'Hara R, Casalunovo T, Conlin LK, D'Arcy M, Frackelton EC, Geiger EA, Haldeman-Englert C, Imielinski M, Kim CE, Medne L, Annaiah K, Bradfield JP, Dabaghyan E, Eckert A, Onyiah CC, Ostapenko S, Otieno FG, Santa E, Shaner JL, Skraban R, Smith RM, Elia J, Goldmuntz E, Spinner NB, Zackai EH, Chiavacci RM, Grundmeier R, Rappaport EF, Grant SF, White PS, Hakonarson H.

Genome Res. 2009 Sep;19(9):1682-90. Epub 2009 Jul 10.PMID: 19592680 [PubMed - in process]Related articles

Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight gene.

Zhao J, Li M, Bradfield JP, Wang K, Zhang H, Sleiman P, Kim CE, Annaiah K, Glaberson W, Glessner JT, Otieno FG, Thomas KA, Garris M, Hou C, Frackelton EC, Chiavacci RM, Berkowitz RI, Hakonarson H, Grant SF.

Diabetes. 2009 Oct;58(10):2414-8. Epub 2009 Jul 10.PMID: 19592620 [PubMed - indexed for MEDLINE]Related articles

Genome-wide association studies in type 1 diabetes, inflammatory bowel disease and other immune-mediated disorders.

Hakonarson H, Grant SF.

Semin Immunol. 2009 Jun 30. [Epub ahead of print]PMID: 19574059 [PubMed - as supplied by publisher]Related articles

Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes.

Bucan M, Abrahams BS, Wang K, Glessner JT, Herman EI, Sonnenblick LI, Alvarez Retuerto AI, Imielinski M, Hadley D, Bradfield JP, Kim C, Gidaya NB, Lindquist I, Hutman T, Sigman M, Kustanovich V, Lajonchere CM, Singleton A, Kim J, Wassink TH, McMahon WM, Owley T, Sweeney JA, Coon H, Nurnberger JI, Li M, Cantor RM, Minshew NJ, Sutcliffe JS, Cook EH, Dawson G, Buxbaum JD, Grant SF, Schellenberg GD, Geschwind DH, Hakonarson H.

PLoS Genet. 2009 Jun;5(6):e1000536. Epub 2009 Jun 26.PMID: 19557195 [PubMed - indexed for MEDLINE]Related articlesFree article

Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes.

Elia J, Gai X, Xie HM, Perin JC, Geiger E, Glessner JT, D'arcy M, Deberardinis R, Frackelton E, Kim C, Lantieri F, Muganga BM, Wang L, Takeda T, Rappaport EF, Grant SF, Berrettini W, Devoto M, Shaikh TH, Hakonarson H, White PS.

Mol Psychiatry. 2009 Jun 23. [Epub ahead of print]PMID: 19546859 [PubMed - as supplied by publisher]Related articles

Copy number variation at 1q21.1 associated with neuroblastoma.

Diskin SJ, Hou C, Glessner JT, Attiyeh EF, Laudenslager M, Bosse K, Cole K, Mossé YP, Wood A, Lynch JE, Pecor K, Diamond M, Winter C, Wang K, Kim C, Geiger EA, McGrady PW, Blakemore AI, London WB, Shaikh TH, Bradfield J, Grant SF, Li H, Devoto M, Rappaport ER, Hakonarson H, Maris JM.

Nature. 2009 Jun 18;459(7249):987-91.PMID: 19536264 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.

Kanetsky PA, Mitra N, Vardhanabhuti S, Li M, Vaughn DJ, Letrero R, Ciosek SL, Doody DR, Smith LM, Weaver J, Albano A, Chen C, Starr JR, Rader DJ, Godwin AK, Reilly MP, Hakonarson H, Schwartz SM, Nathanson KL.

Nat Genet. 2009 Jul;41(7):811-5. Epub 2009 May 31.PMID: 19483682 [PubMed - indexed for MEDLINE]Related articles

The Role of Obesity-associated Loci Identified in Genome-wide Association Studies in the Determination of Pediatric BMI.

Zhao J, Bradfield JP, Li M, Wang K, Zhang H, Kim CE, Annaiah K, Glessner JT, Thomas K, Garris M, Frackelton EC, Otieno FG, Shaner JL, Smith RM, Chiavacci RM, Berkowitz RI, Hakonarson H, Grant SF.

Obesity (Silver Spring). 2009 Dec;17(12):2254-2257. Epub 2009 May 28.PMID: 19478790 [PubMed - as supplied by publisher]Related articles

Association of RASGRP1 with type 1 diabetes is revealed by combined follow-up of two genome-wide studies.

Qu HQ, Grant SF, Bradfield JP, Kim C, Frackelton E, Hakonarson H, Polychronakos C.

J Med Genet. 2009 Aug;46(8):553-4. Epub 2009 May 21.PMID: 19465406 [PubMed - indexed for MEDLINE]Related articles

Nocturnal enuresis: a suggestive endophenotype marker for a subgroup of inattentive attention-deficit/hyperactivity disorder.

Elia J, Takeda T, Deberardinis R, Burke J, Accardo J, Ambrosini PJ, Blum NJ, Brown LW, Lantieri F, Berrettini W, Devoto M, Hakonarson H.

J Pediatr. 2009 Aug;155(2):239-44.e5. Epub 2009 May 15.PMID: 19446845 [PubMed - indexed for MEDLINE]Related articles

Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.

Himes BE, Hunninghake GM, Baurley JW, Rafaels NM, Sleiman P, Strachan DP, Wilk JB, Willis-Owen SA, Klanderman B, Lasky-Su J, Lazarus R, Murphy AJ, Soto-Quiros ME, Avila L, Beaty T, Mathias RA, Ruczinski I, Barnes KC, Celedón JC, Cookson WO, Gauderman WJ, Gilliland FD, Hakonarson H, Lange C, Moffatt MF, O'Connor GT, Raby BA, Silverman EK, Weiss ST.

Am J Hum Genet. 2009 May;84(5):581-93. Epub 2009 May 7.PMID: 19426955 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variations in BARD1 influence susceptibility to high-risk neuroblastoma.

Capasso M, Devoto M, Hou C, Asgharzadeh S, Glessner JT, Attiyeh EF, Mosse YP, Kim C, Diskin SJ, Cole KA, Bosse K, Diamond M, Laudenslager M, Winter C, Bradfield JP, Scott RH, Jagannathan J, Garris M, McConville C, London WB, Seeger RC, Grant SF, Li H, Rahman N, Rappaport E, Hakonarson H, Maris JM.

Nat Genet. 2009 Jun;41(6):718-723. Epub 2009 May 3.PMID: 19412175 [PubMed - as supplied by publisher]Related articles

Autism genome-wide copy number variation reveals ubiquitin and neuronal genes.

Glessner JT, Wang K, Cai G, Korvatska O, Kim CE, Wood S, Zhang H, Estes A, Brune CW, Bradfield JP, Imielinski M, Frackelton EC, Reichert J, Crawford EL, Munson J, Sleiman PM, Chiavacci R, Annaiah K, Thomas K, Hou C, Glaberson W, Flory J, Otieno F, Garris M, Soorya L, Klei L, Piven J, Meyer KJ, Anagnostou E, Sakurai T, Game RM, Rudd DS, Zurawiecki D, McDougle CJ, Davis LK, Miller J, Posey DJ, Michaels S, Kolevzon A, Silverman JM, Bernier R, Levy SE, Schultz RT, Dawson G, Owley T, McMahon WM, Wassink TH, Sweeney JA, Nurnberger JI, Coon H, Sutcliffe JS, Minshew NJ, Grant SF, Bucan M, Cook EH, Buxbaum JD, Devlin B, Schellenberg GD, Hakonarson H.

Nature. 2009 May 28;459(7246):569-73. Epub 2009 Apr 28.PMID: 19404257 [PubMed - indexed for MEDLINE]Related articles

Common genetic variants on 5p14.1 associate with autism spectrum disorders.

Wang K, Zhang H, Ma D, Bucan M, Glessner JT, Abrahams BS, Salyakina D, Imielinski M, Bradfield JP, Sleiman PM, Kim CE, Hou C, Frackelton E, Chiavacci R, Takahashi N, Sakurai T, Rappaport E, Lajonchere CM, Munson J, Estes A, Korvatska O, Piven J, Sonnenblick LI, Alvarez Retuerto AI, Herman EI, Dong H, Hutman T, Sigman M, Ozonoff S, Klin A, Owley T, Sweeney JA, Brune CW, Cantor RM, Bernier R, Gilbert JR, Cuccaro ML, McMahon WM, Miller J, State MW, Wassink TH, Coon H, Levy SE, Schultz RT, Nurnberger JI, Haines JL, Sutcliffe JS, Cook EH, Minshew NJ, Buxbaum JD, Dawson G, Grant SF, Geschwind DH, Pericak-Vance MA, Schellenberg GD, Hakonarson H.

Nature. 2009 May 28;459(7246):528-33. Epub 2009 Apr 28.PMID: 19404256 [PubMed - indexed for MEDLINE]Related articles

Candidate gene analysis in an on-going genome-wide association study of attention-deficit hyperactivity disorder: suggestive association signals in ADRA1A.

Elia J, Capasso M, Zaheer Z, Lantieri F, Ambrosini P, Berrettini W, Devoto M, Hakonarson H.

Psychiatr Genet. 2009 Jun;19(3):134-41.PMID: 19352218 [PubMed - indexed for MEDLINE]Related articles

Genome-wide association studies in type 1 diabetes.

Grant SF, Hakonarson H.

Curr Diab Rep. 2009 Apr;9(2):157-63. Review.PMID: 19323961 [PubMed - indexed for MEDLINE]Related articles

Genomic analysis using high-density single nucleotide polymorphism-based oligonucleotide arrays and multiplex ligation-dependent probe amplification provides a comprehensive analysis of INI1/SMARCB1 in malignant rhabdoid tumors.

Jackson EM, Sievert AJ, Gai X, Hakonarson H, Judkins AR, Tooke L, Perin JC, Xie H, Shaikh TH, Biegel JA.

Clin Cancer Res. 2009 Mar 15;15(6):1923-30. Epub 2009 Mar 10.PMID: 19276269 [PubMed - indexed for MEDLINE]Related articles

Investigation of the locus near MC4R with childhood obesity in Americans of European and African ancestry.

Grant SF, Bradfield JP, Zhang H, Wang K, Kim CE, Annaiah K, Santa E, Glessner JT, Thomas K, Garris M, Frackelton EC, Otieno FG, Shaner JL, Smith RM, Imielinski M, Chiavacci RM, Li M, Berkowitz RI, Hakonarson H.

Obesity (Silver Spring). 2009 Jul;17(7):1461-5. Epub 2009 Mar 5.PMID: 19265794 [PubMed - indexed for MEDLINE]Related articles

Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease.

Wang K, Zhang H, Kugathasan S, Annese V, Bradfield JP, Russell RK, Sleiman PM, Imielinski M, Glessner J, Hou C, Wilson DC, Walters T, Kim C, Frackelton EC, Lionetti P, Barabino A, Van Limbergen J, Guthery S, Denson L, Piccoli D, Li M, Dubinsky M, Silverberg M, Griffiths A, Grant SF, Satsangi J, Baldassano R, Hakonarson H.

Am J Hum Genet. 2009 Mar;84(3):399-405. Epub 2009 Feb 26.PMID: 19249008 [PubMed - indexed for MEDLINE]Related articlesFree article

Genomic landscape of a three-generation pedigree segregating affective disorder.

Yang S, Wang K, Gregory B, Berrettini W, Wang LS, Hakonarson H, Bucan M.

PLoS One. 2009;4(2):e4474. Epub 2009 Feb 13.PMID: 19214233 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.

Myocardial Infarction Genetics Consortium, Kathiresan S, Voight BF, Purcell S, Musunuru K, Ardissino D, Mannucci PM, Anand S, Engert JC, Samani NJ, Schunkert H, Erdmann J, Reilly MP, Rader DJ, Morgan T, Spertus JA, Stoll M, Girelli D, McKeown PP, Patterson CC, Siscovick DS, O'Donnell CJ, Elosua R, Peltonen L, Salomaa V, Schwartz SM, Melander O, Altshuler D, Ardissino D, Merlini PA, Berzuini C, Bernardinelli L, Peyvandi F, Tubaro M, Celli P, Ferrario M, Fetiveau R, Marziliano N, Casari G, Galli M, Ribichini F, Rossi M, Bernardi F, Zonzin P, Piazza A, Mannucci PM, Schwartz SM, Siscovick DS, Yee J, Friedlander Y, Elosua R, Marrugat J, Lucas G, Subirana I, Sala J, Ramos R, Kathiresan S, Meigs JB, Williams G, Nathan DM, MacRae CA, O'Donnell CJ, Salomaa V, Havulinna AS, Peltonen L, Melander O, Berglund G, Voight BF, Kathiresan S, Hirschhorn JN, Asselta R, Duga S, Spreafico M, Musunuru K, Daly MJ, Purcell S, Voight BF, Purcell S, Nemesh J, Korn JM, McCarroll SA, Schwartz SM, Yee J, Kathiresan S, Lucas G, Subirana I, Elosua R, Surti A, Guiducci C, Gianniny L, Mirel D, Parkin M, Burtt N, Gabriel SB, Samani NJ, Thompson JR, Braund PS, Wright BJ, Balmforth AJ, Ball SG, Hall AS; Wellcome Trust Case Control Consortium, Schunkert H, Erdmann J, Linsel-Nitschke P, Lieb W, Ziegler A, König I, Hengstenberg C, Fischer M, Stark K, Grosshennig A, Preuss M, Wichmann HE, Schreiber S, Schunkert H, Samani NJ, Erdmann J, Ouwehand W, Hengstenberg C, Deloukas P, Scholz M, Cambien F, Reilly MP, Li M, Chen Z, Wilensky R, Matthai W, Qasim A, Hakonarson HH, Devaney J, Burnett MS, Pichard AD, Kent KM, Satler L, Lindsay JM, Waksman R, Epstein SE, Rader DJ, Scheffold T, Berger K, Stoll M, Huge A, Girelli D, Martinelli N, Olivieri O, Corrocher R, Morgan T, Spertus JA, McKeown P, Patterson CC, Schunkert H, Erdmann E, Linsel-Nitschke P, Lieb W, Ziegler A, König IR, Hengstenberg C, Fischer M, Stark K, Grosshennig A, Preuss M, Wichmann HE, Schreiber S, Hólm H, Thorleifsson G, Thorsteinsdottir U, Stefansson K, Engert JC, Do R, Xie C, Anand S, Kathiresan S, Ardissino D, Mannucci PM, Siscovick D, O'Donnell CJ, Samani NJ, Melander O, Elosua R, Peltonen L, Salomaa V, Schwartz SM, Altshuler D.

Nat Genet. 2009 Mar;41(3):334-41. Epub 2009 Feb 8.PMID: 19198609 [PubMed - indexed for MEDLINE]Related articlesFree article

Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy.

Attiyeh EF, Diskin SJ, Attiyeh MA, Mossé YP, Hou C, Jackson EM, Kim C, Glessner J, Hakonarson H, Biegel JA, Maris JM.

Genome Res. 2009 Feb;19(2):276-83. Epub 2009 Jan 13. Erratum in: Genome Res. 2009 Mar;19(3):520. PMID: 19141597 [PubMed - indexed for MEDLINE]Related articlesFree article

A 3.1-Mb microdeletion of 3p21.31 associated with cortical blindness, cleft lip, CNS abnormalities, and developmental delay.

Haldeman-Englert CR, Gai X, Perin JC, Ciano M, Halbach SS, Geiger EA, McDonald-McGinn DM, Hakonarson H, Zackai EH, Shaikh TH.

Eur J Med Genet. 2009 Jul-Aug;52(4):265-8. Epub 2008 Dec 13.PMID: 19100872 [PubMed - indexed for MEDLINE]Related articles

ATOM: a powerful gene-based association test by combining optimally weighted markers.

Li M, Wang K, Grant SF, Hakonarson H, Li C.

Bioinformatics. 2009 Feb 15;25(4):497-503. Epub 2008 Dec 15.PMID: 19074959 [PubMed - indexed for MEDLINE]Related articles

SNP array mapping of chromosome 20p deletions: genotypes, phenotypes, and copy number variation.

Kamath BM, Thiel BD, Gai X, Conlin LK, Munoz PS, Glessner J, Clark D, Warthen DM, Shaikh TH, Mihci E, Piccoli DA, Grant SF, Hakonarson H, Krantz ID, Spinner NB.

Hum Mutat. 2009 Mar;30(3):371-8.PMID: 19058200 [PubMed - indexed for MEDLINE]Related articles

Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene.

Sievert AJ, Jackson EM, Gai X, Hakonarson H, Judkins AR, Resnick AC, Sutton LN, Storm PB, Shaikh TH, Biegel JA.

Brain Pathol. 2009 Jul;19(3):449-58. Epub 2008 Oct 21. Erratum in: Brain Pathol. 2009 Jul;19(3):550. PMID: 19016743 [PubMed - indexed for MEDLINE]Related articles

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies.

Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant SF, Farlow DN, Chandrupatla HR, Hansen M, Ajmal S, Papanicolaou GJ, Guo Y, Li M, Derohannessian S, de Bakker PI, Bailey SD, Montpetit A, Edmondson AC, Taylor K, Gai X, Wang SS, Fornage M, Shaikh T, Groop L, Boehnke M, Hall AS, Hattersley AT, Frackelton E, Patterson N, Chiang CW, Kim CE, Fabsitz RR, Ouwehand W, Price AL, Munroe P, Caulfield M, Drake T, Boerwinkle E, Reich D, Whitehead AS, Cappola TP, Samani NJ, Lusis AJ, Schadt E, Wilson JG, Koenig W, McCarthy MI, Kathiresan S, Gabriel SB, Hakonarson H, Anand SS, Reilly M, Engert JC, Nickerson DA, Rader DJ, Hirschhorn JN, Fitzgerald GA.

PLoS One. 2008;3(10):e3583. Epub 2008 Oct 31.PMID: 18974833 [PubMed - indexed for MEDLINE]Related articlesFree article

Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.

Grant SF, Qu HQ, Bradfield JP, Marchand L, Kim CE, Glessner JT, Grabs R, Taback SP, Frackelton EC, Eckert AW, Annaiah K, Lawson ML, Otieno FG, Santa E, Shaner JL, Smith RM, Skraban R, Imielinski M, Chiavacci RM, Grundmeier RW, Stanley CA, Kirsch SE, Waggott D, Paterson AD, Monos DS; DCCT/EDIC Research Group, Polychronakos C, Hakonarson H.

Diabetes. 2009 Jan;58(1):290-5. Epub 2008 Oct 7.PMID: 18840781 [PubMed - indexed for MEDLINE]Related articlesFree article

Modeling genetic inheritance of copy number variations.

Wang K, Chen Z, Tadesse MG, Glessner J, Grant SF, Hakonarson H, Bucan M, Li M.

Nucleic Acids Res. 2008 Dec;36(21):e138. Epub 2008 Oct 2.PMID: 18832372 [PubMed - indexed for MEDLINE]Related articlesFree article

Adjustment of genomic waves in signal intensities from whole-genome SNP genotyping platforms.

Diskin SJ, Li M, Hou C, Yang S, Glessner J, Hakonarson H, Bucan M, Maris JM, Wang K.

Nucleic Acids Res. 2008 Nov;36(19):e126. Epub 2008 Sep 10.PMID: 18784189 [PubMed - indexed for MEDLINE]Related articlesFree article

ORMDL3 variants associated with asthma susceptibility in North Americans of European ancestry.

Sleiman PM, Annaiah K, Imielinski M, Bradfield JP, Kim CE, Frackelton EC, Glessner JT, Eckert AW, Otieno FG, Santa E, Thomas K, Smith RM, Glaberson W, Garris M, Gunnlaugsson S, Chiavacci RM, Allen J, Spergel J, Grundmeier R, Grunstein MM, Magnusson M, Bisgaard H, Grant SF, Hakonarson H.

J Allergy Clin Immunol. 2008 Dec;122(6):1225-7. Epub 2008 Aug 28. No abstract available. PMID: 18760456 [PubMed - indexed for MEDLINE]Related articles

Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.

Kugathasan S, Baldassano RN, Bradfield JP, Sleiman PM, Imielinski M, Guthery SL, Cucchiara S, Kim CE, Frackelton EC, Annaiah K, Glessner JT, Santa E, Willson T, Eckert AW, Bonkowski E, Shaner JL, Smith RM, Otieno FG, Peterson N, Abrams DJ, Chiavacci RM, Grundmeier R, Mamula P, Tomer G, Piccoli DA, Monos DS, Annese V, Denson LA, Grant SF, Hakonarson H.

Nat Genet. 2008 Oct;40(10):1211-5. Epub 2008 Aug 31.PMID: 18758464 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of ALK as a major familial neuroblastoma predisposition gene.

Mossé YP, Laudenslager M, Longo L, Cole KA, Wood A, Attiyeh EF, Laquaglia MJ, Sennett R, Lynch JE, Perri P, Laureys G, Speleman F, Kim C, Hou C, Hakonarson H, Torkamani A, Schork NJ, Brodeur GM, Tonini GP, Rappaport E, Devoto M, Maris JM.

Nature. 2008 Oct 16;455(7215):930-5. Epub 2008 Aug 24.PMID: 18724359 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variants in major histocompatibility complex-linked genes associate with pediatric liver transplant rejection.

Sindhi R, Higgs BW, Weeks DE, Ashokkumar C, Jaffe R, Kim C, Wilson P, Chien N, Glessner J, Talukdar A, Mazariegos G, Barmada MM, Frackleton E, Petro N, Eckert A, Hakonarson H, Ferrell R.

Gastroenterology. 2008 Sep;135(3):830-9, 839.e1-10. Epub 2008 Jun 3.PMID: 18639552 [PubMed - indexed for MEDLINE]Related articles

Association of the TRAF1-C5 locus on chromosome 9 with juvenile idiopathic arthritis.

Behrens EM, Finkel TH, Bradfield JP, Kim CE, Linton L, Casalunovo T, Frackelton EC, Santa E, Otieno FG, Glessner JT, Chiavacci RM, Grant SF, Hakonarson H.

Arthritis Rheum. 2008 Jul;58(7):2206-7. No abstract available. PMID: 18576341 [PubMed - indexed for MEDLINE]Related articlesFree article

Complex management of a patient with a contiguous Xp11.4 gene deletion involving ornithine transcarbamylase: a role for detailed molecular analysis in complex presentations of classical diseases.

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