PubMed

Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells.

Fontés G, Semache M, Hagman DK, Tremblay C, Shah R, Rhodes CJ, Rutter J, Poitout V.

Diabetes. 2009 Sep;58(9):2048-58. Epub 2009 Jun 5.PMID: 19502418 [PubMed - indexed for MEDLINE]Related articlesFree article

The stability and transactivation potential of the mammalian MafA transcription factor are regulated by serine 65 phosphorylation.

Guo S, Burnette R, Zhao L, Vanderford NL, Poitout V, Hagman DK, Henderson E, Ozcan S, Wadzinski BE, Stein R.

J Biol Chem. 2009 Jan 9;284(2):759-65. Epub 2008 Nov 12.PMID: 19004825 [PubMed - indexed for MEDLINE]Related articles

Cyclical and alternating infusions of glucose and intralipid in rats inhibit insulin gene expression and Pdx-1 binding in islets.

Hagman DK, Latour MG, Chakrabarti SK, Fontes G, Amyot J, Tremblay C, Semache M, Lausier JA, Roskens V, Mirmira RG, Jetton TL, Poitout V.

Diabetes. 2008 Feb;57(2):424-31. Epub 2007 Nov 8.PMID: 17991758 [PubMed - indexed for MEDLINE]Related articlesFree article

Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans.

Hagman DK, Hays LB, Parazzoli SD, Poitout V.

J Biol Chem. 2005 Sep 16;280(37):32413-8. Epub 2005 Jun 8.PMID: 15944145 [PubMed - indexed for MEDLINE]Related articlesFree article

The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription.

Zhao L, Guo M, Matsuoka TA, Hagman DK, Parazzoli SD, Poitout V, Stein R.

J Biol Chem. 2005 Mar 25;280(12):11887-94. Epub 2005 Jan 20.PMID: 15665000 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence against the involvement of oxidative stress in fatty acid inhibition of insulin secretion.

Moore PC, Ugas MA, Hagman DK, Parazzoli SD, Poitout V.

Diabetes. 2004 Oct;53(10):2610-6.PMID: 15448091 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of the two-layer (University of Wisconsin solution-perfluorochemical plus O2) method of pancreas preservation on human islet isolation, as assessed by the Edmonton Isolation Protocol.

Matsumoto S, Qualley SA, Goel S, Hagman DK, Sweet IR, Poitout V, Strong DM, Robertson RP, Reems JA.

Transplantation. 2002 Nov 27;74(10):1414-9.PMID: 12451242 [PubMed - indexed for MEDLINE]Related articles