PubMed

Alpha cells beget beta cells.

Liu Z, Habener JF.

Cell. 2009 Aug 7;138(3):424-6.PMID: 19665963 [PubMed - indexed for MEDLINE]Related articles

Stromal cell-derived factor-1 promotes survival of pancreatic beta cells by the stabilisation of beta-catenin and activation of transcription factor 7-like 2 (TCF7L2).

Liu Z, Habener JF.

Diabetologia. 2009 Aug;52(8):1589-98. Epub 2009 May 26.PMID: 19468708 [PubMed - indexed for MEDLINE]Related articles

GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide.

Elahi D, Egan JM, Shannon RP, Meneilly GS, Khatri A, Habener JF, Andersen DK.

Obesity (Silver Spring). 2008 Jul;16(7):1501-9. Epub 2008 Apr 17.PMID: 18421270 [PubMed - indexed for MEDLINE]Related articles

Cytosolic adenylate kinases regulate K-ATP channel activity in human beta-cells.

Stanojevic V, Habener JF, Holz GG, Leech CA.

Biochem Biophys Res Commun. 2008 Apr 11;368(3):614-9. Epub 2008 Feb 1.PMID: 18243136 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation.

Liu Z, Habener JF.

J Biol Chem. 2008 Mar 28;283(13):8723-35. Epub 2008 Jan 23.PMID: 18216022 [PubMed - indexed for MEDLINE]Related articlesFree article

Stromal cell derived factor-1 (SDF-1)/CXCL12 attenuates diabetes in mice and promotes pancreatic beta-cell survival by activation of the prosurvival kinase Akt.

Yano T, Liu Z, Donovan J, Thomas MK, Habener JF.

Diabetes. 2007 Dec;56(12):2946-57. Epub 2007 Sep 18.PMID: 17878289 [PubMed - indexed for MEDLINE]Related articlesFree article

Snail2, a mediator of epithelial-mesenchymal transitions, expressed in progenitor cells of the developing endocrine pancreas.

Rukstalis JM, Habener JF.

Gene Expr Patterns. 2007 Feb;7(4):471-9. Epub 2006 Nov 11.PMID: 17185046 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity.

Ubeda M, Rukstalis JM, Habener JF.

J Biol Chem. 2006 Sep 29;281(39):28858-64. Epub 2006 Aug 3.PMID: 16887799 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 receptor and proglucagon expression in mouse skin.

List JF, He H, Habener JF.

Regul Pept. 2006 May 15;134(2-3):149-57. Epub 2006 Mar 6.PMID: 16631262 [PubMed - indexed for MEDLINE]Related articles

Transcription factor snail modulates hormone expression in established endocrine pancreatic cell lines.

Rukstalis JM, Ubeda M, Johnson MV, Habener JF.

Endocrinology. 2006 Jun;147(6):2997-3006. Epub 2006 Mar 23.PMID: 16556769 [PubMed - indexed for MEDLINE]Related articlesFree article

Islets break off from the mainland.

Rukstalis JM, Habener JF.

Nat Med. 2006 Mar;12(3):273-4. No abstract available. PMID: 16520767 [PubMed - indexed for MEDLINE]Related articles

IPF-1/MODY4 gene missense mutation in an Italian family with type 2 and gestational diabetes.

Gragnoli C, Stanojevic V, Gorini A, Von Preussenthal GM, Thomas MK, Habener JF.

Metabolism. 2005 Aug;54(8):983-8.PMID: 16092045 [PubMed - indexed for MEDLINE]Related articles

Linkage study of the glucagon receptor gene with type 2 diabetes mellitus in Italians.

Gragnoli C, Milord E, Habener JF.

Metabolism. 2005 Jun;54(6):786-7. Erratum in: Metabolism. 2005 Aug;54(8):1125. Gragnoli, Claudio [corrected to Gragnoli, Claudia]. PMID: 15931615 [PubMed - indexed for MEDLINE]Related articles

Redifferentiation of insulin-secreting cells after in vitro expansion of adult human pancreatic islet tissue.

Lechner A, Nolan AL, Blacken RA, Habener JF.

Biochem Biophys Res Commun. 2005 Feb 11;327(2):581-8.PMID: 15629153 [PubMed - indexed for MEDLINE]Related articles

Minireview: transcriptional regulation in pancreatic development.

Habener JF, Kemp DM, Thomas MK.

Endocrinology. 2005 Mar;146(3):1025-34. Epub 2004 Dec 16. Review.PMID: 15604203 [PubMed - indexed for MEDLINE]Related articlesFree article

A perspective on pancreatic stem/progenitor cells.

Habener JF.

Pediatr Diabetes. 2004;5 Suppl 2:29-37. Review.PMID: 15601372 [PubMed - indexed for MEDLINE]Related articles

Triple genetic variation in the HNF-4alpha gene is associated with early-onset type 2 diabetes mellitus in a philippino family.

Gragnoli C, Menzinger Von Preussenthal G, Habener JF.

Metabolism. 2004 Aug;53(8):959-63.PMID: 15281001 [PubMed - indexed for MEDLINE]Related articles

Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4.

Ogawa N, List JF, Habener JF, Maki T.

Diabetes. 2004 Jul;53(7):1700-5.PMID: 15220193 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide 1 agonists and the development and growth of pancreatic beta-cells.

List JF, Habener JF.

Am J Physiol Endocrinol Metab. 2004 Jun;286(6):E875-81. Review.PMID: 15140754 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell-density-dependent regulation of actin gene expression due to changes in actin treadmilling.

Schmitt-Ney M, Habener JF.

Exp Cell Res. 2004 Apr 15;295(1):236-44.PMID: 15051506 [PubMed - indexed for MEDLINE]Related articles

Pancreas duodenum homeobox-1 transcriptional activation requires interactions with p300.

Stanojevic V, Habener JF, Thomas MK.

Endocrinology. 2004 Jun;145(6):2918-28. Epub 2004 Mar 4.PMID: 15001545 [PubMed - indexed for MEDLINE]Related articlesFree article

No evidence for significant transdifferentiation of bone marrow into pancreatic beta-cells in vivo.

Lechner A, Yang YG, Blacken RA, Wang L, Nolan AL, Habener JF.

Diabetes. 2004 Mar;53(3):616-23.PMID: 14988245 [PubMed - indexed for MEDLINE]Related articlesFree article

Human pancreatic islet-derived progenitor cell engraftment in immunocompetent mice.

Abraham EJ, Kodama S, Lin JC, Ubeda M, Faustman DL, Habener JF.

Am J Pathol. 2004 Mar;164(3):817-30.PMID: 14982836 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic beta-cells.

Ubeda M, Kemp DM, Habener JF.

Endocrinology. 2004 Jun;145(6):3023-31. Epub 2004 Feb 19.PMID: 14976144 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of 3 months of continuous subcutaneous administration of glucagon-like peptide 1 in elderly patients with type 2 diabetes.

Meneilly GS, Greig N, Tildesley H, Habener JF, Egan JM, Elahi D.

Diabetes Care. 2003 Oct;26(10):2835-41.PMID: 14514588 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of glucagon-like peptide-1 receptor and calcium-sensing receptor signaling by L-histidine.

Leech CA, Habener JF.

Endocrinology. 2003 Nov;144(11):4851-8. Epub 2003 Jul 24.PMID: 12959987 [PubMed - indexed for MEDLINE]Related articlesFree article

CHOP transcription factor phosphorylation by casein kinase 2 inhibits transcriptional activation.

Ubeda M, Habener JF.

J Biol Chem. 2003 Oct 17;278(42):40514-20. Epub 2003 Jul 21.PMID: 12876286 [PubMed - indexed for MEDLINE]Related articlesFree article

Bone marrow stem cells find a path to the pancreas.

Lechner A, Habener JF.

Nat Biotechnol. 2003 Jul;21(7):755-6. No abstract available. PMID: 12833093 [PubMed - indexed for MEDLINE]Related articles

Regulation of Pax4 paired homeodomain gene by neuron-restrictive silencer factor.

Kemp DM, Lin JC, Habener JF.

J Biol Chem. 2003 Sep 12;278(37):35057-62. Epub 2003 Jun 26.PMID: 12829700 [PubMed - indexed for MEDLINE]Related articlesFree article

The Role of Pancreatic Duodenum Homeobox Protein-1 in the Development of Diabetes Mellitus.

Habener JF.

Drug News Perspect. 2002 Oct;15(8):491-497.PMID: 12677187 [PubMed - as supplied by publisher]Related articles

Defective melanocortin 4 receptors in hyperphagia and morbid obesity.

List JF, Habener JF.

N Engl J Med. 2003 Mar 20;348(12):1160-3. No abstract available. PMID: 12646673 [PubMed - indexed for MEDLINE]Related articles

Developmental aspects of the endocrine pancreas.

Kemp DM, Thomas MK, Habener JF.

Rev Endocr Metab Disord. 2003 Mar;4(1):5-17. Review. No abstract available. PMID: 12618555 [PubMed - indexed for MEDLINE]Related articles

Effect of glucagon-like peptide 1 (7-36 amide) on insulin-mediated glucose uptake in patients with type 1 diabetes.

Meneilly GS, McIntosh CH, Pederson RA, Habener JF, Ehlers MR, Egan JM, Elahi D.

Diabetes Care. 2003 Mar;26(3):837-42.PMID: 12610046 [PubMed - indexed for MEDLINE]Related articlesFree article

Huntington's disease of the endocrine pancreas: insulin deficiency and diabetes mellitus due to impaired insulin gene expression.

Andreassen OA, Dedeoglu A, Stanojevic V, Hughes DB, Browne SE, Leech CA, Ferrante RJ, Habener JF, Beal MF, Thomas MK.

Neurobiol Dis. 2002 Dec;11(3):410-24.PMID: 12586550 [PubMed - indexed for MEDLINE]Related articles

Stem/progenitor cells derived from adult tissues: potential for the treatment of diabetes mellitus.

Lechner A, Habener JF.

Am J Physiol Endocrinol Metab. 2003 Feb;284(2):E259-66. Review.PMID: 12531740 [PubMed - indexed for MEDLINE]Related articlesFree article

NRSF/REST confers transcriptional repression of the GPR10 gene via a putative NRSE/RE-1 located in the 5' promoter region.

Kemp DM, Lin JC, Ubeda M, Habener JF.

FEBS Lett. 2002 Nov 6;531(2):193-8.PMID: 12417311 [PubMed - indexed for MEDLINE]Related articles

Synergistic effect of dimethyl sulfoxide on glucagon-like peptide 1 (GLP-1)-stimulated insulin secretion and gene transcription in INS-1 cells: characterization and implications.

Kemp DM, Habener JF.

Biochem Pharmacol. 2002 Aug 15;64(4):689-97.PMID: 12167488 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1 augments insulin-mediated glucose uptake in the obese state.

Egan JM, Meneilly GS, Habener JF, Elahi D.

J Clin Endocrinol Metab. 2002 Aug;87(8):3768-73.PMID: 12161508 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells.

Abraham EJ, Leech CA, Lin JC, Zulewski H, Habener JF.

Endocrinology. 2002 Aug;143(8):3152-61.PMID: 12130581 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification and functional characterization of melatonin Mel 1a receptors in pancreatic beta cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling.

Kemp DM, Ubeda M, Habener JF.

Mol Cell Endocrinol. 2002 Jun 14;191(2):157-66.PMID: 12062899 [PubMed - indexed for MEDLINE]Related articles

Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter.

Lechner A, Leech CA, Abraham EJ, Nolan AL, Habener JF.

Biochem Biophys Res Commun. 2002 May 3;293(2):670-4.PMID: 12054520 [PubMed - indexed for MEDLINE]Related articles

Brn-4 transcription factor expression targeted to the early developing mouse pancreas induces ectopic glucagon gene expression in insulin-producing beta cells.

Hussain MA, Miller CP, Habener JF.

J Biol Chem. 2002 May 3;277(18):16028-32. Epub 2002 Feb 7.PMID: 11834725 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 (7-37) augments insulin-mediated glucose uptake in elderly patients with diabetes.

Meneilly GS, McIntosh CH, Pederson RA, Habener JF, Gingerich R, Egan JM, Elahi D.

J Gerontol A Biol Sci Med Sci. 2001 Nov;56(11):M681-5.PMID: 11682575 [PubMed - indexed for MEDLINE]Related articles

Effect of glucagon-like peptide 1 on non-insulin-mediated glucose uptake in the elderly patient with diabetes.

Meneilly GS, McIntosh CH, Pederson RA, Habener JF, Gingerich R, Egan JM, Finegood DT, Elahi D.

Diabetes Care. 2001 Nov;24(11):1951-6.PMID: 11679463 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of aging and diabetes on the enteroinsular axis.

Korosi J, McIntosh CH, Pederson RA, Demuth HU, Habener JF, Gingerich R, Egan JM, Elahi D, Meneilly GS.

J Gerontol A Biol Sci Med Sci. 2001 Sep;56(9):M575-9.PMID: 11524451 [PubMed - indexed for MEDLINE]Related articles

Development of diabetes mellitus in aging transgenic mice following suppression of pancreatic homeoprotein IDX-1.

Thomas MK, Devon ON, Lee JH, Peter A, Schlosser DA, Tenser MS, Habener JF.

J Clin Invest. 2001 Jul;108(2):319-29.PMID: 11457885 [PubMed - indexed for MEDLINE]Related articlesFree article

Stress-inducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and -independent mechanisms.

Maytin EV, Ubeda M, Lin JC, Habener JF.

Exp Cell Res. 2001 Jul 15;267(2):193-204.PMID: 11426938 [PubMed - indexed for MEDLINE]Related articles

Improved glucose tolerance and acinar dysmorphogenesis by targeted expression of transcription factor PDX-1 to the exocrine pancreas.

Heller RS, Stoffers DA, Bock T, Svenstrup K, Jensen J, Horn T, Miller CP, Habener JF, Madsen OD, Serup P.

Diabetes. 2001 Jul;50(7):1553-61.PMID: 11423476 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 (7-37) augments insulin release in elderly patients with diabetes.

Meneilly GS, McIntosh CH, Pederson RA, Habener JF, Gingerich R, Egan JM, Elahi D.

Diabetes Care. 2001 May;24(5):964-5. No abstract available. PMID: 11347771 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel alternatively spliced exon in the extracellular ligand-binding domain of the pituitary adenylate cyclase-activating polypeptide (PACAP) type 1 receptor (PAC1R) selectively increases ligand affinity and alters signal transduction coupling during spermatogenesis.

Daniel PB, Kieffer TJ, Leech CA, Habener JF.

J Biol Chem. 2001 Apr 20;276(16):12938-44. Epub 2001 Jan 29.PMID: 11278585 [PubMed - indexed for MEDLINE]Related articlesFree article