PubMed

Utility of virtual crossmatch in sensitized patients awaiting heart transplantation.

Stehlik J, Islam N, Hurst D, Kfoury AG, Movsesian MA, Fuller A, Delgado JC, Hammond ME, Gilbert EM, Renlund DG, Bader F, Fisher PW, Bull DA, Singhal AK, Eckels DD.

J Heart Lung Transplant. 2009 Nov;28(11):1129-34. Epub 2009 Sep 26.PMID: 19782589 [PubMed - in process]Related articles

Metastamir: the field of metastasis-regulatory microRNA is spreading.

Hurst DR, Edmonds MD, Welch DR.

Cancer Res. 2009 Oct 1;69(19):7495-8. Epub 2009 Sep 22.PMID: 19773429 [PubMed - in process]Related articles

Linking metastasis suppression with metastamiR regulation.

Edmonds MD, Hurst DR, Welch DR.

Cell Cycle. 2009 Sep 1;8(17):2673-5. Epub 2009 Sep 23. No abstract available. PMID: 19690456 [PubMed - in process]Related articles

Breast cancer metastasis suppressor 1 coordinately regulates metastasis-associated microRNA expression.

Edmonds MD, Hurst DR, Vaidya KS, Stafford LJ, Chen D, Welch DR.

Int J Cancer. 2009 Oct 15;125(8):1778-85.PMID: 19585508 [PubMed - indexed for MEDLINE]Related articles

Discovery of sodium 6-[(5-chloro-2-{[(4-chloro-2-fluorophenyl)methyl]oxy}phenyl)methyl]-2-pyridinecarboxylate (GSK269984A) an EP(1) receptor antagonist for the treatment of inflammatory pain.

Hall A, Billinton A, Brown SH, Chowdhury A, Clayton NM, Giblin GM, Gibson M, Goldsmith PA, Hurst DN, Naylor A, Peet CF, Scoccitti T, Wilson AW, Winchester W.

Bioorg Med Chem Lett. 2009 May 1;19(9):2599-603. Epub 2009 Mar 3.PMID: 19332369 [PubMed - indexed for MEDLINE]Related articles

Nuclear magnetic resonance and circular dichroism study of metastin (Kisspeptin-54) structure in solution.

Shin R, Welch DR, Mishra VK, Nash KT, Hurst DR, Rama Krishna N.

Clin Exp Metastasis. 2009;26(6):527-33. Epub 2009 Mar 24.PMID: 19308666 [PubMed - indexed for MEDLINE]Related articles

Inhibition of CXCR4 by CTCE-9908 inhibits breast cancer metastasis to lung and bone.

Richert MM, Vaidya KS, Mills CN, Wong D, Korz W, Hurst DR, Welch DR.

Oncol Rep. 2009 Mar;21(3):761-7.PMID: 19212637 [PubMed - indexed for MEDLINE]Related articles

Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis.

Hurst DR, Edmonds MD, Scott GK, Benz CC, Vaidya KS, Welch DR.

Cancer Res. 2009 Feb 15;69(4):1279-83. Epub 2009 Feb 3.PMID: 19190326 [PubMed - indexed for MEDLINE]Related articles

Over-expression of the BRMS1 family member SUDS3 does not suppress metastasis of human cancer cells.

Silveira AC, Hurst DR, Vaidya KS, Ayer DE, Welch DR.

Cancer Lett. 2009 Apr 8;276(1):32-7. Epub 2008 Dec 13.PMID: 19070953 [PubMed - indexed for MEDLINE]Related articles

Residues accessible in the binding-site crevice of transmembrane helix 6 of the CB2 cannabinoid receptor.

Nebane NM, Hurst DP, Carrasquer CA, Qiao Z, Reggio PH, Song ZH.

Biochemistry. 2008 Dec 30;47(52):13811-21.PMID: 19053233 [PubMed - indexed for MEDLINE]Related articles

Metastasis Research Society-American Association For Cancer Research Joint Conference on Metastasis.

Welch DR, Cooper CR, Hurst DR, Lynch CC, Martin MD, Vaidya KS, VanSaun MN, Mastro AM.

Cancer Res. 2008 Dec 1;68(23):9578-82. No abstract available. PMID: 19047132 [PubMed - indexed for MEDLINE]Related articles

Discovery of GSK345931A: An EP(1) receptor antagonist with efficacy in preclinical models of inflammatory pain.

Hall A, Brown SH, Budd C, Clayton NM, Giblin GM, Goldsmith P, Hayhow TG, Hurst DN, Naylor A, Anthony Rawlings D, Scoccitti T, Wilson AW, Winchester WJ.

Bioorg Med Chem Lett. 2009 Jan 15;19(2):497-501. Epub 2008 Nov 14.PMID: 19036582 [PubMed - indexed for MEDLINE]Related articles

Ligand-binding architecture of human CB2 cannabinoid receptor: evidence for receptor subtype-specific binding motif and modeling GPCR activation.

Pei Y, Mercier RW, Anday JK, Thakur GA, Zvonok AM, Hurst D, Reggio PH, Janero DR, Makriyannis A.

Chem Biol. 2008 Nov 24;15(11):1207-19.PMID: 19022181 [PubMed - indexed for MEDLINE]Related articles

Multiple forms of BRMS1 are differentially expressed in the MCF10 isogenic breast cancer progression model.

Hurst DR, Xie Y, Edmonds MD, Welch DR.

Clin Exp Metastasis. 2009;26(2):89-96. Epub 2008 Oct 8.PMID: 18841483 [PubMed - indexed for MEDLINE]Related articles

Breast cancer metastasis suppressor-1 differentially modulates growth factor signaling.

Vaidya KS, Harihar S, Phadke PA, Stafford LJ, Hurst DR, Hicks DG, Casey G, DeWald DB, Welch DR.

J Biol Chem. 2008 Oct 17;283(42):28354-60. Epub 2008 Jul 29.PMID: 18664570 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy of allergy immunotherapy as a treatment for patients with chronic otitis media with effusion.

Hurst DS.

Int J Pediatr Otorhinolaryngol. 2008 Aug;72(8):1215-23. Epub 2008 Jun 9.PMID: 18541312 [PubMed - indexed for MEDLINE]Related articles

Analogs of JHU75528, a PET ligand for imaging of cerebral cannabinoid receptors (CB1): development of ligands with optimized lipophilicity and binding affinity.

Fan H, Kotsikorou E, Hoffman AF, Ravert HT, Holt D, Hurst DP, Lupica CR, Reggio PH, Dannals RF, Horti AG.

Eur J Med Chem. 2009 Feb;44(2):593-608. Epub 2008 Apr 18.PMID: 18511157 [PubMed - indexed for MEDLINE]Related articles

Does treatment with inhaled corticosteroids improve outcomes in infants with RSV infection?

Hurst D, Chadek R, Mold J.

J Okla State Med Assoc. 2008 Mar;101(3):55-6. No abstract available. PMID: 18472710 [PubMed - indexed for MEDLINE]Related articles

Non-acidic pyrazole EP1 receptor antagonists with in vivo analgesic efficacy.

Hall A, Billinton A, Brown SH, Clayton NM, Chowdhury A, Giblin GM, Goldsmith P, Hayhow TG, Hurst DN, Kilford IR, Naylor A, Passingham B, Winyard L.

Bioorg Med Chem Lett. 2008 Jun 1;18(11):3392-9. Epub 2008 Apr 11.PMID: 18462938 [PubMed - indexed for MEDLINE]Related articles

Discovery of a novel indole series of EP1 receptor antagonists by scaffold hopping.

Hall A, Billinton A, Brown SH, Chowdhury A, Giblin GM, Goldsmith P, Hurst DN, Naylor A, Patel S, Scoccitti T, Theobald PJ.

Bioorg Med Chem Lett. 2008 Apr 15;18(8):2684-90. Epub 2008 Mar 10.PMID: 18378447 [PubMed - indexed for MEDLINE]Related articles

Atypical presentation of soft-tissue mass with gonococcal infection in the hand.

Hurst DW, Thompson MA, Hofmeister EP.

Am J Orthop. 2008 Jan;37(1):E14-5. No abstract available. PMID: 18309389 [PubMed - indexed for MEDLINE]Related articles

BRMS1 suppresses breast cancer experimental metastasis to multiple organs by inhibiting several steps of the metastatic process.

Phadke PA, Vaidya KS, Nash KT, Hurst DR, Welch DR.

Am J Pathol. 2008 Mar;172(3):809-17. Epub 2008 Feb 14.PMID: 18276787 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel methylene-linked heterocyclic EP1 receptor antagonists.

Hall A, Bit RA, Brown SH, Chowdhury A, Giblin GM, Hurst DN, Kilford IR, Lewell X, Naylor A, Scoccitti T.

Bioorg Med Chem Lett. 2008 Mar 1;18(5):1592-7. Epub 2008 Jan 19.PMID: 18262416 [PubMed - indexed for MEDLINE]Related articles

Alterations of BRMS1-ARID4A interaction modify gene expression but still suppress metastasis in human breast cancer cells.

Hurst DR, Xie Y, Vaidya KS, Mehta A, Moore BP, Accavitti-Loper MA, Samant RS, Saxena R, Silveira AC, Welch DR.

J Biol Chem. 2008 Mar 21;283(12):7438-44. Epub 2008 Jan 22.PMID: 18211900 [PubMed - indexed for MEDLINE]Related articlesFree article

A MSC-ing link in metastasis?

Hurst DR, Welch DR.

Nat Med. 2007 Nov;13(11):1289-91. No abstract available. PMID: 17987025 [PubMed - indexed for MEDLINE]Related articlesFree article

Decabromodiphenyl ether (deca-BDE) commercial mixture components, and other PBDEs, in airborne particles at a UK site.

Wilford BH, Thomas GO, Jones KC, Davison B, Hurst DK.

Environ Int. 2008 Apr;34(3):412-9. Epub 2007 Oct 24.PMID: 17961649 [PubMed - indexed for MEDLINE]Related articles

Conformational memories with variable bond angles.

Whitnell RM, Hurst DP, Reggio PH, Guarnieri F.

J Comput Chem. 2008 Apr 15;29(5):741-52.PMID: 17876759 [PubMed - indexed for MEDLINE]Related articles

Diffusion-weighted imaging findings on MRI as the sole radiographic findings in a child with proven herpes simplex encephalitis.

Obeid M, Franklin J, Shrestha S, Johnson L, Quattromani F, Hurst D.

Pediatr Radiol. 2007 Nov;37(11):1159-62. Epub 2007 Sep 15.PMID: 17874320 [PubMed - indexed for MEDLINE]Related articles

Helix 8 Leu in the CB1 cannabinoid receptor contributes to selective signal transduction mechanisms.

Anavi-Goffer S, Fleischer D, Hurst DP, Lynch DL, Barnett-Norris J, Shi S, Lewis DL, Mukhopadhyay S, Howlett AC, Reggio PH, Abood ME.

J Biol Chem. 2007 Aug 24;282(34):25100-13. Epub 2007 Jun 26.PMID: 17595161 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutation studies of Ser7.39 and Ser2.60 in the human CB1 cannabinoid receptor: evidence for a serine-induced bend in CB1 transmembrane helix 7.

Kapur A, Hurst DP, Fleischer D, Whitnell R, Thakur GA, Makriyannis A, Reggio PH, Abood ME.

Mol Pharmacol. 2007 Jun;71(6):1512-24. Epub 2007 Mar 23.PMID: 17384224 [PubMed - indexed for MEDLINE]Related articlesFree article

Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy.

Nash KT, Phadke PA, Navenot JM, Hurst DR, Accavitti-Loper MA, Sztul E, Vaidya KS, Frost AR, Kappes JC, Peiper SC, Welch DR.

J Natl Cancer Inst. 2007 Feb 21;99(4):309-21. Erratum in: J Natl Cancer Inst. 2007 Jul 20;99(12):977. PMID: 17312308 [PubMed - indexed for MEDLINE]Related articlesFree article

Adult male replacement in socially monogamous equatorial Saki monkeys (Pithecia aequatorialis).

Di Fiore A, Fernandez-Duque E, Hurst D.

Folia Primatol (Basel). 2007;78(2):88-98.PMID: 17303938 [PubMed - indexed for MEDLINE]Related articles

Angiotensin-converting enzyme as a target for the development of novel insect growth regulators.

Isaac RE, Lamango NS, Ekbote U, Taylor CA, Hurst D, Weaver RJ, Carhan A, Burnham S, Shirras AD.

Peptides. 2007 Jan;28(1):153-62. Epub 2006 Dec 8. Review.PMID: 17157962 [PubMed - indexed for MEDLINE]Related articles

A phase 2 study of rituximab in combination with recombinant interleukin-2 for rituximab-refractory indolent non-Hodgkin's lymphoma.

Khan KD, Emmanouilides C, Benson DM Jr, Hurst D, Garcia P, Michelson G, Milan S, Ferketich AK, Piro L, Leonard JP, Porcu P, Eisenbeis CF, Banks AL, Chen L, Byrd JC, Caligiuri MA.

Clin Cancer Res. 2006 Dec 1;12(23):7046-53.PMID: 17145827 [PubMed - indexed for MEDLINE]Related articlesFree article

Developing and implementing quality initiatives in the ICU: strategies and outcomes.

Harrigan S, Hurst D, Lee C, Christie V, Wolfe RB, Morrical D, Kleinpell R.

Crit Care Nurs Clin North Am. 2006 Dec;18(4):469-79, ix.PMID: 17118301 [PubMed - indexed for MEDLINE]Related articles

The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain.

Giblin GM, Bit RA, Brown SH, Chaignot HM, Chowdhury A, Chessell IP, Clayton NM, Coleman T, Hall A, Hammond B, Hurst DN, Michel AD, Naylor A, Novelli R, Scoccitti T, Spalding D, Tang SP, Wilson AW, Wilson R.

Bioorg Med Chem Lett. 2007 Jan 15;17(2):385-9. Epub 2006 Oct 20.PMID: 17084082 [PubMed - indexed for MEDLINE]Related articles

Biarylpyrazole inverse agonists at the cannabinoid CB1 receptor: importance of the C-3 carboxamide oxygen/lysine3.28(192) interaction.

Hurst D, Umejiego U, Lynch D, Seltzman H, Hyatt S, Roche M, McAllister S, Fleischer D, Kapur A, Abood M, Shi S, Jones J, Lewis D, Reggio P.

J Med Chem. 2006 Oct 5;49(20):5969-87.PMID: 17004712 [PubMed - indexed for MEDLINE]Related articles

Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone.

Hurst DR, Mehta A, Moore BP, Phadke PA, Meehan WJ, Accavitti MA, Shevde LA, Hopper JE, Xie Y, Welch DR, Samant RS.

Biochem Biophys Res Commun. 2006 Oct 6;348(4):1429-35. Epub 2006 Aug 10.PMID: 16919237 [PubMed - indexed for MEDLINE]Related articlesFree article

Walking with modafinil and its use in diplegic cerebral palsy: retrospective review.

Hurst DL, Lajara-Nanson WA, Lance-Fish ME.

J Child Neurol. 2006 Apr;21(4):294-7.PMID: 16900924 [PubMed - indexed for MEDLINE]Related articles

Matrix metalloproteinase inhibitors as prospective agents for the prevention and treatment of cardiovascular and neoplastic diseases.

Sang QX, Jin Y, Newcomer RG, Monroe SC, Fang X, Hurst DR, Lee S, Cao Q, Schwartz MA.

Curr Top Med Chem. 2006;6(4):289-316. Review.PMID: 16611144 [PubMed - indexed for MEDLINE]Related articles

Modafinil for drooling in cerebral palsy.

Hurst D, Cedrone N.

J Child Neurol. 2006 Feb;21(2):112-4.PMID: 16566873 [PubMed - indexed for MEDLINE]Related articles

Discovery of novel biaryl heterocyclic EP1 receptor antagonists.

Hall A, Bit RA, Brown SH, Chaignot HM, Chessell IP, Coleman T, Giblin GM, Hurst DN, Kilford IR, Lewell XQ, Michel AD, Mohamed S, Naylor A, Novelli R, Skinner L, Spalding DJ, Tang SP, Wilson RJ.

Bioorg Med Chem Lett. 2006 May 15;16(10):2666-71. Epub 2006 Feb 28.PMID: 16503138 [PubMed - indexed for MEDLINE]Related articles

Orally active purine-based inhibitors of the heat shock protein 90.

Biamonte MA, Shi J, Hong K, Hurst DC, Zhang L, Fan J, Busch DJ, Karjian PL, Maldonado AA, Sensintaffar JL, Yang YC, Kamal A, Lough RE, Lundgren K, Burrows FJ, Timony GA, Boehm MF, Kasibhatla SR.

J Med Chem. 2006 Jan 26;49(2):817-28.PMID: 16420067 [PubMed - indexed for MEDLINE]Related articles

(-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor.

Picone RP, Khanolkar AD, Xu W, Ayotte LA, Thakur GA, Hurst DP, Abood ME, Reggio PH, Fournier DJ, Makriyannis A.

Mol Pharmacol. 2005 Dec;68(6):1623-35. Epub 2005 Sep 12.PMID: 16157695 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of enzyme activity of and cell-mediated substrate cleavage by membrane type 1 matrix metalloproteinase by newly developed mercaptosulphide inhibitors.

Hurst DR, Schwartz MA, Jin Y, Ghaffari MA, Kozarekar P, Cao J, Sang QX.

Biochem J. 2005 Dec 15;392(Pt 3):527-36.PMID: 16026329 [PubMed - indexed for MEDLINE]Related articlesFree article

Adamantyl cannabinoids: a novel class of cannabinergic ligands.

Lu D, Meng Z, Thakur GA, Fan P, Steed J, Tartal CL, Hurst DP, Reggio PH, Deschamps JR, Parrish DA, George C, Järbe TU, Lamb RJ, Makriyannis A.

J Med Chem. 2005 Jul 14;48(14):4576-85.PMID: 15999995 [PubMed - indexed for MEDLINE]Related articles

Suppression of murine mammary carcinoma metastasis by the murine ortholog of breast cancer metastasis suppressor 1 (Brms1).

Samant RS, Debies MT, Hurst DR, Moore BP, Shevde LA, Welch DR.

Cancer Lett. 2006 Apr 28;235(2):260-5. Epub 2005 Jun 22.PMID: 15978719 [PubMed - indexed for MEDLINE]Related articles

AMP-activated protein kinase kinase activity and phosphorylation of AMP-activated protein kinase in contracting muscle of sedentary and endurance-trained rats.

Hurst D, Taylor EB, Cline TD, Greenwood LJ, Compton CL, Lamb JD, Winder WW.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E710-5. Epub 2005 May 31.PMID: 15928023 [PubMed - indexed for MEDLINE]Related articlesFree article

A video database of moving faces and people.

O'Toole AJ, Harms J, Snow SL, Hurst DR, Pappas MR, Ayyad JH, Abdi H.

IEEE Trans Pattern Anal Mach Intell. 2005 May;27(5):812-6.PMID: 15875802 [PubMed - indexed for MEDLINE]Related articles

Cysteine 2.59(89) in the second transmembrane domain of human CB2 receptor is accessible within the ligand binding crevice: evidence for possible CB2 deviation from a rhodopsin template.

Zhang R, Hurst DP, Barnett-Norris J, Reggio PH, Song ZH.

Mol Pharmacol. 2005 Jul;68(1):69-83. Epub 2005 Apr 19.PMID: 15840841 [PubMed - indexed for MEDLINE]Related articlesFree article