PubMed

Colon cancer and the elderly: From screening to treatment in management of GI disease in the elderly.

Holt PR, Kozuch P, Mewar S.

Best Pract Res Clin Gastroenterol. 2009;23(6):889-907.PMID: 19942166 [PubMed - in process]

Western-style diets induce oxidative stress and dysregulate immune responses in the colon in a mouse model of sporadic colon cancer.

Erdelyi I, Levenkova N, Lin EY, Pinto JT, Lipkin M, Quimby FW, Holt PR.

J Nutr. 2009 Nov;139(11):2072-8. Epub 2009 Sep 16.PMID: 19759248 [PubMed - in process]Related articles

Chemoprevention of colorectal neoplasia by estrogen: potential role of vitamin D activity.

Protiva P, Cross HS, Hopkins ME, Kállay E, Bises G, Dreyhaupt E, Augenlicht L, Lipkin M, Lesser M, Livote E, Holt PR.

Cancer Prev Res (Phila Pa). 2009 Jan;2(1):43-51.PMID: 19139017 [PubMed - indexed for MEDLINE]Related articles

Chemoprevention of colorectal neoplasia.

Holick MF, Holt PR.

Gastroenterology. 2008 Oct;135(4):1427-8; author reply 1428. No abstract available. PMID: 18789938 [PubMed - indexed for MEDLINE]Related articles

New insights into calcium, dairy and colon cancer.

Holt PR.

World J Gastroenterol. 2008 Jul 28;14(28):4429-33. Review.PMID: 18680219 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth inhibition of colon cancer cells by polyisoprenylated benzophenones is associated with induction of the endoplasmic reticulum response.

Protiva P, Hopkins ME, Baggett S, Yang H, Lipkin M, Holt PR, Kennelly EJ, Bernard WI.

Int J Cancer. 2008 Aug 1;123(3):687-94.PMID: 18470880 [PubMed - indexed for MEDLINE]Related articles

Soy isoflavone intake and estrogen excretion patterns in young women: effect of probiotic administration.

Cohen LA, Crespin JS, Wolper C, Zang EA, Pittman B, Zhao Z, Holt PR.

In Vivo. 2007 May-Jun;21(3):507-12.PMID: 17591361 [PubMed - indexed for MEDLINE]Related articles

Intestinal malabsorption in the elderly.

Holt PR.

Dig Dis. 2007;25(2):144-50. Review.PMID: 17468550 [PubMed - indexed for MEDLINE]Related articles

Re: Severe toxic hepatitis.

Pinillos H, Holt PR, Thung S.

Dig Dis Sci. 2007 Sep;52(9):2460-1. Epub 2007 Apr 6. No abstract available. PMID: 17415657 [PubMed - indexed for MEDLINE]Related articles

Non-steroidal anti-inflammatory drugs have bacteriostatic and bactericidal activity against Helicobacter pylori.

Shirin H, Moss SF, Kancherla S, Kancherla K, Holt PR, Weinstein IB, Sordillo EM.

J Gastroenterol Hepatol. 2006 Sep;21(9):1388-93.PMID: 16911681 [PubMed - indexed for MEDLINE]Related articles

Effects of aging of the population.

Holt PR.

Gastroenterology. 2006 Apr;130(4):1371; author reply 1371-2. No abstract available. PMID: 16618435 [PubMed - indexed for MEDLINE]Related articles

Calcium plus vitamin D alters preneoplastic features of colorectal adenomas and rectal mucosa.

Holt PR, Bresalier RS, Ma CK, Liu KF, Lipkin M, Byrd JC, Yang K.

Cancer. 2006 Jan 15;106(2):287-96.PMID: 16353199 [PubMed - indexed for MEDLINE]Related articlesFree article

Curcumin therapy in inflammatory bowel disease: a pilot study.

Holt PR, Katz S, Kirshoff R.

Dig Dis Sci. 2005 Nov;50(11):2191-3.PMID: 16240238 [PubMed - indexed for MEDLINE]Related articles

Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells.

Agarwal B, Swaroop P, Protiva P, Raj SV, Shirin H, Holt PR.

Apoptosis. 2003 Dec;8(6):649-54.PMID: 14739610 [PubMed - indexed for MEDLINE]Related articles

Gastrointestinal diseases in the elderly.

Holt PR.

Curr Opin Clin Nutr Metab Care. 2003 Jan;6(1):41-8. Review.PMID: 12496679 [PubMed - indexed for MEDLINE]Related articles

Comparison of calcium supplementation or low-fat dairy foods on epithelial cell proliferation and differentiation.

Holt PR, Wolper C, Moss SF, Yang K, Lipkin M.

Nutr Cancer. 2001;41(1-2):150-5.PMID: 12094618 [PubMed - indexed for MEDLINE]Related articles

Colorectal cancer prevention: prospects for the first decade of the 21st century.

Holt PR.

Prev Med. 2002 Jun;34(6):563-6. Review. No abstract available. PMID: 12052014 [PubMed - indexed for MEDLINE]Related articles

Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells.

Agarwal B, Halmos B, Feoktistov AS, Protiva P, Ramey WG, Chen M, Pothoulakis C, Lamont JT, Holt PR.

Carcinogenesis. 2002 Mar;23(3):521-8.PMID: 11895868 [PubMed - indexed for MEDLINE]Related articlesFree article

Colonic epithelial cell proliferation decreases with increasing levels of serum 25-hydroxy vitamin D.

Holt PR, Arber N, Halmos B, Forde K, Kissileff H, McGlynn KA, Moss SF, Kurihara N, Fan K, Yang K, Lipkin M.

Cancer Epidemiol Biomarkers Prev. 2002 Jan;11(1):113-9. Erratum in: Cancer Epidemiol Biomarkers Prev 2002 May;11(5):501. PMID: 11815408 [PubMed - indexed for MEDLINE]Related articlesFree article

p21(WAF1/cip1) is an important determinant of intestinal cell response to sulindac in vitro and in vivo.

Yang W, Velcich A, Mariadason J, Nicholas C, Corner G, Houston M, Edelmann W, Kucherlapati R, Holt PR, Augenlicht LH.

Cancer Res. 2001 Aug 15;61(16):6297-302.PMID: 11507085 [PubMed - indexed for MEDLINE]Related articlesFree article

Diarrhea and malabsorption in the elderly.

Holt PR.

Gastroenterol Clin North Am. 2001 Jun;30(2):427-44. Review.PMID: 11432299 [PubMed - indexed for MEDLINE]Related articles

25-hydroxyvitamin D-1alpha-hydroxylase in normal and malignant colon tissue.

Tangpricha V, Flanagan JN, Whitlatch LW, Tseng CC, Chen TC, Holt PR, Lipkin MS, Holick MF.

Lancet. 2001 May 26;357(9269):1673-4.PMID: 11425375 [PubMed - indexed for MEDLINE]Related articles

Increased gastric epithelial cell apoptosis associated with colonization with cagA + Helicobacter pylori strains.

Moss SF, Sordillo EM, Abdalla AM, Makarov V, Hanzely Z, Perez-Perez GI, Blaser MJ, Holt PR.

Cancer Res. 2001 Feb 15;61(4):1406-11.PMID: 11245442 [PubMed - indexed for MEDLINE]Related articlesFree article

Antiproliferative effects of S-allylmercaptocysteine on colon cancer cells when tested alone or in combination with sulindac sulfide.

Shirin H, Pinto JT, Kawabata Y, Soh JW, Delohery T, Moss SF, Murty V, Rivlin RS, Holt PR, Weinstein IB.

Cancer Res. 2001 Jan 15;61(2):725-31.PMID: 11212275 [PubMed - indexed for MEDLINE]Related articlesFree article

Peptic disease in elderly patients.

Khaghan N, Holt PR.

Can J Gastroenterol. 2000 Dec;14(11):922-8. Review.PMID: 11125182 [PubMed - indexed for MEDLINE]Related articlesFree article

Gastrin-mediated alterations in gastric epithelial apoptosis and proliferation in a mastomys rodent model of gastric neoplasia.

Kidd M, Tang LH, Modlin IM, Zhang T, Chin K, Holt PR, Moss SF.

Digestion. 2000;62(2-3):143-51.PMID: 11025361 [PubMed - indexed for MEDLINE]Related articles

Ziprasidone and the pharmacokinetics of a combined oral contraceptive.

Muirhead GJ, Harness J, Holt PR, Oliver S, Anziano RJ.

Br J Clin Pharmacol. 2000;49 Suppl 1:49S-56S.PMID: 10771454 [PubMed - indexed for MEDLINE]Related articlesFree article

Studies of calcium in food supplements in humans.

Holt PR.

Ann N Y Acad Sci. 1999;889:128-37. Review.PMID: 10668489 [PubMed - indexed for MEDLINE]Related articles

Abnormalities in the expression of cell cycle-related proteins in tumors of the small bowel.

Arber N, Hibshoosh H, Yasui W, Neugut AI, Hibshoosh A, Yao Y, Sgambato A, Yamamoto H, Shapira I, Rosenman D, Fabian I, Weinstein IB, Tahara E, Holt PR.

Cancer Epidemiol Biomarkers Prev. 1999 Dec;8(12):1101-5.PMID: 10613343 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased and aberrant nuclear lamin expression in gastrointestinal tract neoplasms.

Moss SF, Krivosheyev V, de Souza A, Chin K, Gaetz HP, Chaudhary N, Worman HJ, Holt PR.

Gut. 1999 Nov;45(5):723-9.PMID: 10517909 [PubMed - indexed for MEDLINE]Related articlesFree article

Dairy foods and prevention of colon cancer: human studies.

Holt PR.

J Am Coll Nutr. 1999 Oct;18(5 Suppl):379S-391S. Review.PMID: 10511318 [PubMed - indexed for MEDLINE]Related articlesFree article

Lovastatin augments sulindac-induced apoptosis in colon cancer cells and potentiates chemopreventive effects of sulindac.

Agarwal B, Rao CV, Bhendwal S, Ramey WR, Shirin H, Reddy BS, Holt PR.

Gastroenterology. 1999 Oct;117(4):838-47.PMID: 10500066 [PubMed - indexed for MEDLINE]Related articles

Role of thyroid hormone in stimulating liver repopulation in the rat by transplanted hepatocytes.

Oren R, Dabeva MD, Karnezis AN, Petkov PM, Rosencrantz R, Sandhu JP, Moss SF, Wang S, Hurston E, Laconi E, Holt PR, Thung SN, Zhu L, Shafritz DA.

Hepatology. 1999 Oct;30(4):903-13.PMID: 10498641 [PubMed - indexed for MEDLINE]Related articles

Overexpression of cyclin D1 occurs in both squamous carcinomas and adenocarcinomas of the esophagus and in adenocarcinomas of the stomach.

Arber N, Gammon MD, Hibshoosh H, Britton JA, Zhang Y, Schonberg JB, Roterdam H, Fabian I, Holt PR, Weinstein IB.

Hum Pathol. 1999 Sep;30(9):1087-92.PMID: 10492044 [PubMed - indexed for MEDLINE]Related articles

Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells.

Agarwal B, Bhendwal S, Halmos B, Moss SF, Ramey WG, Holt PR.

Clin Cancer Res. 1999 Aug;5(8):2223-9.PMID: 10473109 [PubMed - indexed for MEDLINE]Related articlesFree article

Human right and left colon differ in epithelial cell apoptosis and in expression of Bak, a pro-apoptotic Bcl-2 homologue.

Liu LU, Holt PR, Krivosheyev V, Moss SF.

Gut. 1999 Jul;45(1):45-50.PMID: 10369703 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of K-ras mutations with p16 methylation in human colon cancer.

Guan RJ, Fu Y, Holt PR, Pardee AB.

Gastroenterology. 1999 May;116(5):1063-71.PMID: 10220498 [PubMed - indexed for MEDLINE]Related articles

Calcium intake and colon cancer biomarkers.

Holt PR, Lipkin M, Newmark H.

JAMA. 1999 Apr 7;281(13):1172-3. No abstract available. PMID: 10199422 [PubMed - indexed for MEDLINE]Related articles

Modulation of abnormal colonic epithelial cell proliferation and differentiation by low-fat dairy foods: a randomized controlled trial.

Holt PR, Atillasoy EO, Gilman J, Guss J, Moss SF, Newmark H, Fan K, Yang K, Lipkin M.

JAMA. 1998 Sep 23-30;280(12):1074-9.PMID: 9757855 [PubMed - indexed for MEDLINE]Related articlesFree article

Insensitivity of the CLOtest for H. pylori, especially in the elderly.

Abdalla AM, Sordillo EM, Hanzely Z, Perez-Perez GI, Blaser MJ, Holt PR, Moss SF.

Gastroenterology. 1998 Jul;115(1):243-4. No abstract available. PMID: 9659344 [PubMed - indexed for MEDLINE]Related articles

Insensitivity of the CLOtest for H. pylori, Especially in the Elderly.

Abdalla AM, Sordillo EM, Hanzely Z, Perez-Perez GI, Blaser MJ, Holt PR, Moss SF.

Gastroenterology. 1998 Jul;115(1):243b-244. No abstract available. PMID: 9649489 [PubMed - as supplied by publisher]Related articles

Diet restriction increases apoptosis in the gut of aging rats.

Holt PR, Moss SF, Heydari AR, Richardson A.

J Gerontol A Biol Sci Med Sci. 1998 May;53(3):B168-72.PMID: 9597039 [PubMed - indexed for MEDLINE]Related articles

Dairy product-rich diets and cytotoxicity of fecal water.

Newmark HL, Holt PR.

Am J Clin Nutr. 1998 May;67(5):946-7. No abstract available. PMID: 9583855 [PubMed - indexed for MEDLINE]Related articles

Amaranthin lectin binding in the rat colon: response to dietary manipulation.

Atillasoy EO, Kapetanakis A, Itzkowitz SH, Holt PR.

Mt Sinai J Med. 1998 Mar;65(2):146-53.PMID: 9520519 [PubMed - indexed for MEDLINE]Related articles

A K-ras oncogene increases resistance to sulindac-induced apoptosis in rat enterocytes.

Arber N, Han EK, Sgambato A, Piazza GA, Delohery TM, Begemann M, Weghorst CM, Kim NH, Pamukcu R, Ahnen DJ, Reed JC, Weinstein IB, Holt PR.

Gastroenterology. 1997 Dec;113(6):1892-900.PMID: 9394728 [PubMed - indexed for MEDLINE]Related articles

Apoptosis in gastric epithelial cells is induced by Helicobacter pylori and accompanied by increased expression of BAK.

Chen G, Sordillo EM, Ramey WG, Reidy J, Holt PR, Krajewski S, Reed JC, Blaser MJ, Moss SF.

Biochem Biophys Res Commun. 1997 Oct 20;239(2):626-32.PMID: 9344882 [PubMed - indexed for MEDLINE]Related articles

Are right- and left-sided colon neoplasms distinct tumors?

Distler P, Holt PR.

Dig Dis. 1997 Jul-Oct;15(4-5):302-11. Review.PMID: 9359018 [PubMed - indexed for MEDLINE]Related articles

Helicobacter pylori cagA+ strains and dissociation of gastric epithelial cell proliferation from apoptosis.

Peek RM Jr, Moss SF, Tham KT, Pérez-Pérez GI, Wang S, Miller GG, Atherton JC, Holt PR, Blaser MJ.

J Natl Cancer Inst. 1997 Jun 18;89(12):863-8.PMID: 9196252 [PubMed - indexed for MEDLINE]Related articlesFree article

Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells.

Arber N, Doki Y, Han EK, Sgambato A, Zhou P, Kim NH, Delohery T, Klein MG, Holt PR, Weinstein IB.

Cancer Res. 1997 Apr 15;57(8):1569-74.PMID: 9108461 [PubMed - indexed for MEDLINE]Related articlesFree article

Is Ki-67 a better proliferative marker in the colon than proliferating cell nuclear antigen?

Holt PR, Moss SF, Kapetanakis AM, Petrotos A, Wang S.

Cancer Epidemiol Biomarkers Prev. 1997 Feb;6(2):131-5.PMID: 9037564 [PubMed - indexed for MEDLINE]Related articlesFree article