PubMed

International Bordetella pertussis assay standardization and harmonization meeting report. Centers for Disease Control and Prevention, Atlanta, Georgia, United States, 19-20 July 2007.

Tondella ML, Carlone GM, Messonnier N, Quinn CP, Meade BD, Burns DL, Cherry JD, Guiso N, Hewlett EL, Edwards KM, Xing D, Giammanco A, Wirsing von König CH, Han L, Hueston L, Robbins JB, Powell M, Mink CM, Poolman JT, Hildreth SW, Lynn F, Morris A.

Vaccine. 2009 Feb 5;27(6):803-14. Epub 2008 Dec 9.PMID: 19071179 [PubMed - indexed for MEDLINE]Related articles

Bordetella pertussis adenylate cyclase toxin (ACT) induces cyclooxygenase-2 (COX-2) in murine macrophages and is facilitated by ACT interaction with CD11b/CD18 (Mac-1).

Perkins DJ, Gray MC, Hewlett EL, Vogel SN.

Mol Microbiol. 2007 Nov;66(4):1003-15. Epub 2007 Oct 10.PMID: 17927697 [PubMed - indexed for MEDLINE]Related articles

A fully integrated microfluidic genetic analysis system with sample-in-answer-out capability.

Easley CJ, Karlinsey JM, Bienvenue JM, Legendre LA, Roper MG, Feldman SH, Hughes MA, Hewlett EL, Merkel TJ, Ferrance JP, Landers JP.

Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19272-7. Epub 2006 Dec 11.PMID: 17159153 [PubMed - indexed for MEDLINE]Related articlesFree article

Meiotic resumption in response to luteinizing hormone is independent of a Gi family G protein or calcium in the mouse oocyte.

Mehlmann LM, Kalinowski RR, Ross LF, Parlow AF, Hewlett EL, Jaffe LA.

Dev Biol. 2006 Nov 15;299(2):345-55. Epub 2006 Aug 5.PMID: 16949564 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage cytotoxicity produced by adenylate cyclase toxin from Bordetella pertussis: more than just making cyclic AMP!

Hewlett EL, Donato GM, Gray MC.

Mol Microbiol. 2006 Jan;59(2):447-59.PMID: 16390441 [PubMed - indexed for MEDLINE]Related articles

Adenylate cyclase toxin (ACT) from Bordetella hinzii: characterization and differences from ACT of Bordetella pertussis.

Donato GM, Hsia HL, Green CS, Hewlett EL.

J Bacteriol. 2005 Nov;187(22):7579-88.PMID: 16267282 [PubMed - indexed for MEDLINE]Related articlesFree article

Oligomeric behavior of Bordetella pertussis adenylate cyclase toxin in solution.

Lee SJ, Gray MC, Zu K, Hewlett EL.

Arch Biochem Biophys. 2005 Jun 1;438(1):80-7. Epub 2005 Apr 19.PMID: 15878155 [PubMed - indexed for MEDLINE]Related articles

Clinical practice. Pertussis--not just for kids.

Hewlett EL, Edwards KM.

N Engl J Med. 2005 Mar 24;352(12):1215-22. Review. No abstract available. PMID: 15788498 [PubMed - indexed for MEDLINE]Related articles

Newly secreted adenylate cyclase toxin is responsible for intoxication of target cells by Bordetella pertussis.

Gray MC, Donato GM, Jones FR, Kim T, Hewlett EL.

Mol Microbiol. 2004 Sep;53(6):1709-19.PMID: 15341649 [PubMed - indexed for MEDLINE]Related articles

Mechanism of association of adenylate cyclase toxin with the surface of Bordetella pertussis: a role for toxin-filamentous haemagglutinin interaction.

Zaretzky FR, Gray MC, Hewlett EL.

Mol Microbiol. 2002 Sep;45(6):1589-98.PMID: 12354227 [PubMed - indexed for MEDLINE]Related articles

Protein kinase A translocation and insulin secretion in pancreatic beta-cells: studies with adenylate cyclase toxin from Bordetella pertussis.

Gao Z, Young RA, Trucco MM, Greene SR, Hewlett EL, Matschinsky FM, Wolf BA.

Biochem J. 2002 Dec 1;368(Pt 2):397-404. Erratum in: Biochem J. 2003 Feb 1;369(Pt 3):739.. PMID: 12180908 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural consequences of divalent metal binding by the adenylyl cyclase toxin of Bordetella pertussis.

Rhodes CR, Gray MC, Watson JM, Muratore TL, Kim SB, Hewlett EL, Grisham CM.

Arch Biochem Biophys. 2001 Nov 15;395(2):169-76.PMID: 11697853 [PubMed - indexed for MEDLINE]Related articles

Translocation-specific conformation of adenylate cyclase toxin from Bordetella pertussis inhibits toxin-mediated hemolysis.

Gray MC, Lee SJ, Gray LS, Zaretzky FR, Otero AS, Szabo G, Hewlett EL.

J Bacteriol. 2001 Oct;183(20):5904-10.PMID: 11566989 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenylate cyclase toxin from Bordetella pertussis: current concepts and problems in the study of toxin functions.

Hewlett EL, Kim KJ, Lee SJ, Gray MC.

Int J Med Microbiol. 2000 Oct;290(4-5):333-5.PMID: 11111907 [PubMed - indexed for MEDLINE]Related articles

Neutralizing antibodies to adenylate cyclase toxin promote phagocytosis of Bordetella pertussis by human neutrophils.

Weingart CL, Mobberley-Schuman PS, Hewlett EL, Gray MC, Weiss AA.

Infect Immun. 2000 Dec;68(12):7152-5.PMID: 11083845 [PubMed - indexed for MEDLINE]Related articlesFree article

Escherichia coli alpha-hemolysin (HlyA) is heterogeneously acylated in vivo with 14-, 15-, and 17-carbon fatty acids.

Lim KB, Walker CR, Guo L, Pellett S, Shabanowitz J, Hunt DF, Hewlett EL, Ludwig A, Goebel W, Welch RA, Hackett M.

J Biol Chem. 2000 Nov 24;275(47):36698-702.PMID: 10978310 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of binding of adenylate cyclase toxin to target cells by flow cytometry.

Gray MC, Ross W, Kim K, Hewlett EL.

Infect Immun. 1999 Sep;67(9):4393-9.PMID: 10456879 [PubMed - indexed for MEDLINE]Related articlesFree article

A commentary on the pathogenesis of pertussis.

Hewlett EL.

Clin Infect Dis. 1999 Jun;28 Suppl 2:S94-8. Review.PMID: 10447025 [PubMed - indexed for MEDLINE]Related articles

Epitope mapping of monoclonal antibodies against Bordetella pertussis adenylate cyclase toxin.

Lee SJ, Gray MC, Guo L, Sebo P, Hewlett EL.

Infect Immun. 1999 May;67(5):2090-5.PMID: 10225859 [PubMed - indexed for MEDLINE]Related articlesFree article

Serological correlates of immunity to Bordetella pertussis.

Hewlett EL, Halperin SA.

Vaccine. 1998 Dec;16(20):1899-900. No abstract available. PMID: 9796040 [PubMed - indexed for MEDLINE]Related articles

Pertussis: current concepts of pathogenesis and prevention.

Hewlett EL.

Pediatr Infect Dis J. 1997 Apr;16(4 Suppl):S78-84. Review.PMID: 9109161 [PubMed - indexed for MEDLINE]Related articles

Role of pertussis toxin A subunit in neutrophil migration and vascular permeability.

Brito GA, Souza MH, Melo-Filho AA, Hewlett EL, Lima AA, Flores CA, Ribeiro RA.

Infect Immun. 1997 Mar;65(3):1114-8.PMID: 9038326 [PubMed - indexed for MEDLINE]Related articlesFree article

Preparation and composition of acellular pertussis vaccines. Consideration of potential effects on vaccine efficacy.

Hewlett EL.

Dev Biol Stand. 1997;89:143-51. Review.PMID: 9272344 [PubMed - indexed for MEDLINE]Related articles

Adenylate cyclase in striatal cholinergic interneurons regulates acetylcholine release.

Login IS, Hewlett EL.

Brain Res. 1996 Oct 7;735(2):330-4.PMID: 8911674 [PubMed - indexed for MEDLINE]Related articles

Acellular pertussis trial.

Hewlett EL.

Pediatrics. 1996 Oct;98(4 Pt 1):800. No abstract available. PMID: 8885972 [PubMed - indexed for MEDLINE]Related articles

ATP shortens atrial action potential duration in the dog: role of adenosine, the vagus nerve, and G protein.

Pelleg A, Hurt CM, Hewlett EL.

Can J Physiol Pharmacol. 1996 Jan;74(1):15-22.PMID: 8963948 [PubMed - indexed for MEDLINE]Related articles

Hemolytic, but not cell-invasive activity, of adenylate cyclase toxin is selectively affected by differential fatty-acylation in Escherichia coli.

Hackett M, Walker CB, Guo L, Gray MC, Van Cuyk S, Ullmann A, Shabanowitz J, Hunt DF, Hewlett EL, Sebo P.

J Biol Chem. 1995 Sep 1;270(35):20250-3.PMID: 7657593 [PubMed - indexed for MEDLINE]Related articlesFree article

Membrane depolarization prevents cell invasion by Bordetella pertussis adenylate cyclase toxin.

Otero AS, Yi XB, Gray MC, Szabo G, Hewlett EL.

J Biol Chem. 1995 Apr 28;270(17):9695-7.PMID: 7730345 [PubMed - indexed for MEDLINE]Related articlesFree article

Pertussis toxin from Bordetella pertussis blocks neutrophil migration and neutrophil-dependent edema in response to inflammation.

Thomazzi SM, Souza MH, Melo-Filho AA, Hewlett EL, Lima AA, Ribeiro RA.

Braz J Med Biol Res. 1995 Jan;28(1):120-4.PMID: 7581020 [PubMed - indexed for MEDLINE]Related articles

Effect of temperature and host factors on the activities of pertussis toxin and Bordetella adenylate cyclase.

Murayama T, Hewlett EL, Maloney NJ, Justice JM, Moss J.

Biochemistry. 1994 Dec 27;33(51):15293-7.PMID: 7803392 [PubMed - indexed for MEDLINE]Related articles

Internal lysine palmitoylation in adenylate cyclase toxin from Bordetella pertussis.

Hackett M, Guo L, Shabanowitz J, Hunt DF, Hewlett EL.

Science. 1994 Oct 21;266(5184):433-5.PMID: 7939682 [PubMed - indexed for MEDLINE]Related articles

Adenylate cyclase toxin from Bordetella pertussis produces ion conductance across artificial lipid bilayers in a calcium- and polarity-dependent manner.

Szabo G, Gray MC, Hewlett EL.

J Biol Chem. 1994 Sep 9;269(36):22496-9.PMID: 8077197 [PubMed - indexed for MEDLINE]Related articlesFree article

Pertussis toxin activates platelets through an interaction with platelet glycoprotein Ib.

Sindt KA, Hewlett EL, Redpath GT, Rappuoli R, Gray LS, Vandenberg SR.

Infect Immun. 1994 Aug;62(8):3108-14.PMID: 8039878 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of adenylate cyclase toxin from a mutant of Bordetella pertussis defective in the activator gene, cyaC.

Hewlett EL, Gray MC, Ehrmann IE, Maloney NJ, Otero AS, Gray L, Allietta M, Szabo G, Weiss AA, Barry EM.

J Biol Chem. 1993 Apr 15;268(11):7842-8.PMID: 8385122 [PubMed - indexed for MEDLINE]Related articlesFree article

Antibodies to Bordetella pertussis adenylate cyclase toxin in neonatal and maternal sera.

Arciniega JL, Hewlett EL, Edwards KM, Burns DL.

FEMS Immunol Med Microbiol. 1993 Apr;6(4):325-30.PMID: 8499896 [PubMed - indexed for MEDLINE]Related articles

Enzymatic activity of adenylate cyclase toxin from Bordetella pertussis is not required for hemolysis.

Ehrmann IE, Weiss AA, Goodwin MS, Gray MC, Barry E, Hewlett EL.

FEBS Lett. 1992 Jun 8;304(1):51-6. Erratum in: FEBS Lett 1993 Mar 29;320(1):86. PMID: 1319923 [PubMed - indexed for MEDLINE]Related articles

Pertussis in adults: significance for disease transmission and immunisation policy.

Hewlett EL.

J Med Microbiol. 1992 Mar;36(3):141-2. No abstract available. PMID: 1548687 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenylate cyclase toxin from Bordetella pertussis. Conformational change associated with toxin activity.

Hewlett EL, Gray L, Allietta M, Ehrmann I, Gordon VM, Gray MC.

J Biol Chem. 1991 Sep 15;266(26):17503-8.PMID: 1894634 [PubMed - indexed for MEDLINE]Related articlesFree article

Construction and characterization of Bordetella pertussis mutants lacking the vir-regulated P.69 outer membrane protein.

Roberts M, Fairweather NF, Leininger E, Pickard D, Hewlett EL, Robinson A, Hayward C, Dougan G, Charles IG.

Mol Microbiol. 1991 Jun;5(6):1393-404.PMID: 1787793 [PubMed - indexed for MEDLINE]Related articles

Hemolytic activity of adenylate cyclase toxin from Bordetella pertussis.

Ehrmann IE, Gray MC, Gordon VM, Gray LS, Hewlett EL.

FEBS Lett. 1991 Jan 14;278(1):79-83.PMID: 1993477 [PubMed - indexed for MEDLINE]Related articles

Bordetella pertussis adenylate cyclase toxin and hemolytic activities require a second gene, cyaC, for activation.

Barry EM, Weiss AA, Ehrmann IE, Gray MC, Hewlett EL, Goodwin MS.

J Bacteriol. 1991 Jan;173(2):720-6.PMID: 1987161 [PubMed - indexed for MEDLINE]Related articlesFree article

Human serologic response to envelope-associated proteins and adenylate cyclase toxin of Bordetella pertussis.

Arciniega JL, Hewlett EL, Johnson FD, Deforest A, Wassilak SG, Onorato IM, Manclark CR, Burns DL.

J Infect Dis. 1991 Jan;163(1):135-42.PMID: 1984460 [PubMed - indexed for MEDLINE]Related articles

Transforming growth factor beta enhances parathyroid hormone stimulation of adenylate cyclase in clonal osteoblast-like cells.

Gutierrez GE, Mundy GR, Manning DR, Hewlett EL, Katz MS.

J Cell Physiol. 1990 Sep;144(3):438-47.PMID: 2391378 [PubMed - indexed for MEDLINE]Related articles

Adenosine and related compounds counteract tumor necrosis factor-alpha inhibition of neutrophil migration: implication of a novel cyclic AMP-independent action on the cell surface.

Sullivan GW, Linden J, Hewlett EL, Carper HT, Hylton JB, Mandell GL.

J Immunol. 1990 Sep 1;145(5):1537-44.PMID: 2166764 [PubMed - indexed for MEDLINE]Related articles

Protective antibodies in pertussis.

Cherry JD, Hewlett EL, Mortimer EA Jr.

J Pediatr. 1990 Aug;117(2 Pt 1):347-8. No abstract available. PMID: 2380841 [PubMed - indexed for MEDLINE]Related articles

Phorbol esters enhance the cyclic GMP response of T84 cells to the heat-stable enterotoxin of Escherichia coli (STa).

Weikel CS, Spann CL, Chambers CP, Crane JK, Linden J, Hewlett EL.

Infect Immun. 1990 May;58(5):1402-7.PMID: 1969850 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenylate cyclase toxin from Bordetella pertussis. Identification and purification of the holotoxin molecule.

Hewlett EL, Gordon VM, McCaffery JD, Sutherland WM, Gray MC.

J Biol Chem. 1989 Nov 15;264(32):19379-84.PMID: 2553737 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis. Different processes for interaction with and entry into target cells.

Gordon VM, Young WW Jr, Lechler SM, Gray MC, Leppla SH, Hewlett EL.

J Biol Chem. 1989 Sep 5;264(25):14792-6.PMID: 2504710 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection of Bordetella pertussis by determination of adenylate cyclase activity.

Wirsing von Koenig CH, Tacken A, Hewlett EL.

Eur J Clin Microbiol Infect Dis. 1989 Jul;8(7):633-6.PMID: 2550232 [PubMed - indexed for MEDLINE]Related articles

Failure of pertussis toxin to inhibit activation of guanylate cyclase by the heat-stable enterotoxin of Escherichia coli (STa) in the T84 cell line.

Crane JK, Hewlett EL, Weikel CS.

Infect Immun. 1989 Apr;57(4):1186-91.PMID: 2564375 [PubMed - indexed for MEDLINE]Related articlesFree article