PubMed

Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase.

Jones LE Jr, Ying L, Hofseth AB, Jelezcova E, Sobol RW, Ambs S, Harris CC, Espey MG, Hofseth LJ, Wyatt MD.

Carcinogenesis. 2009 Oct 28. [Epub ahead of print]PMID: 19864471 [PubMed - as supplied by publisher]Related articles

MicroRNA expression in squamous cell carcinoma and adenocarcinoma of the esophagus: associations with survival.

Mathé EA, Nguyen GH, Bowman ED, Zhao Y, Budhu A, Schetter AJ, Braun R, Reimers M, Kumamoto K, Hughes D, Altorki NK, Casson AG, Liu CG, Wang XW, Yanaihara N, Hagiwara N, Dannenberg AJ, Miyashita M, Croce CM, Harris CC.

Clin Cancer Res. 2009 Oct 1;15(19):6192-200. Epub 2009 Sep 29.PMID: 19789312 [PubMed - in process]Related articles

Genetic reduction of circulating insulin-like growth factor-1 inhibits azoxymethane-induced colon tumorigenesis in mice.

Olivo-Marston SE, Hursting SD, Lavigne J, Perkins SN, Maarouf RS, Yakar S, Harris CC.

Mol Carcinog. 2009 Sep 16;48(12):1071-1076. [Epub ahead of print]PMID: 19760669 [PubMed - as supplied by publisher]Related articles

Lung cancer in never smokers: molecular profiles and therapeutic implications.

Rudin CM, Avila-Tang E, Harris CC, Herman JG, Hirsch FR, Pao W, Schwartz AG, Vahakangas KH, Samet JM.

Clin Cancer Res. 2009 Sep 15;15(18):5646-61.PMID: 19755392 [PubMed - in process]Related articles

Plasma microRNAs: a potential biomarker for colorectal cancer?

Schetter AJ, Harris CC.

Gut. 2009 Oct;58(10):1318-9. No abstract available. PMID: 19749133 [PubMed - indexed for MEDLINE]Related articles

Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma.

Schetter AJ, Nguyen GH, Bowman ED, Mathé EA, Yuen ST, Hawkes JE, Croce CM, Leung SY, Harris CC.

Clin Cancer Res. 2009 Sep 15;15(18):5878-87. Epub 2009 Sep 8.PMID: 19737943 [PubMed - in process]Related articles

p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence.

Fujita K, Mondal AM, Horikawa I, Nguyen GH, Kumamoto K, Sohn JJ, Bowman ED, Mathe EA, Schetter AJ, Pine SR, Ji H, Vojtesek B, Bourdon JC, Lane DP, Harris CC.

Nat Cell Biol. 2009 Sep;11(9):1135-42. Epub 2009 Aug 23.PMID: 19701195 [PubMed - indexed for MEDLINE]Related articles

Recurring mutations found by sequencing an acute myeloid leukemia genome.

Mardis ER, Ding L, Dooling DJ, Larson DE, McLellan MD, Chen K, Koboldt DC, Fulton RS, Delehaunty KD, McGrath SD, Fulton LA, Locke DP, Magrini VJ, Abbott RM, Vickery TL, Reed JS, Robinson JS, Wylie T, Smith SM, Carmichael L, Eldred JM, Harris CC, Walker J, Peck JB, Du F, Dukes AF, Sanderson GE, Brummett AM, Clark E, McMichael JF, Meyer RJ, Schindler JK, Pohl CS, Wallis JW, Shi X, Lin L, Schmidt H, Tang Y, Haipek C, Wiechert ME, Ivy JV, Kalicki J, Elliott G, Ries RE, Payton JE, Westervelt P, Tomasson MH, Watson MA, Baty J, Heath S, Shannon WD, Nagarajan R, Link DC, Walter MJ, Graubert TA, DiPersio JF, Wilson RK, Ley TJ.

N Engl J Med. 2009 Sep 10;361(11):1058-66. Epub 2009 Aug 5.PMID: 19657110 [PubMed - indexed for MEDLINE]Related articles

Ionizing radiation-induced oxidative stress alters miRNA expression.

Simone NL, Soule BP, Ly D, Saleh AD, Savage JE, Degraff W, Cook J, Harris CC, Gius D, Mitchell JB.

PLoS One. 2009 Jul 27;4(7):e6377.PMID: 19633716 [PubMed - indexed for MEDLINE]Related articlesFree article

MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers.

Seike M, Goto A, Okano T, Bowman ED, Schetter AJ, Horikawa I, Mathe EA, Jen J, Yang P, Sugimura H, Gemma A, Kudoh S, Croce CM, Harris CC.

Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12085-90. Epub 2009 Jul 13.PMID: 19597153 [PubMed - indexed for MEDLINE]Related articles

ING proteins as potential anticancer drug targets.

Unoki M, Kumamoto K, Harris CC.

Curr Drug Targets. 2009 May;10(5):442-54. Review.PMID: 19442116 [PubMed - indexed for MEDLINE]Related articles

Effects of youth tobacco access and possession policy interventions on heavy adolescent smokers.

Jason LA, Pokorny SB, Adams ML, Topliff A, Harris CC, Hunt Y.

Int J Environ Res Public Health. 2009 Jan;6(1):1-9. Epub 2008 Dec 23.PMID: 19440265 [PubMed - indexed for MEDLINE]Related articlesFree article

ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression.

Kumamoto K, Fujita K, Kurotani R, Saito M, Unoki M, Hagiwara N, Shiga H, Bowman ED, Yanaihara N, Okamura S, Nagashima M, Miyamoto K, Takenoshita S, Yokota J, Harris CC.

Int J Cancer. 2009 Sep 15;125(6):1306-15.PMID: 19437536 [PubMed - indexed for MEDLINE]Related articles

Reviewing the current classification of inhibitor of growth family proteins.

Unoki M, Kumamoto K, Takenoshita S, Harris CC.

Cancer Sci. 2009 Jul;100(7):1173-9. Epub 2009 Apr 28. Review.PMID: 19432890 [PubMed - indexed for MEDLINE]Related articles

Telomere recombination requires the MUS81 endonuclease.

Zeng S, Xiang T, Pandita TK, Gonzalez-Suarez I, Gonzalo S, Harris CC, Yang Q.

Nat Cell Biol. 2009 May;11(5):616-23. Epub 2009 Apr 12.PMID: 19363487 [PubMed - indexed for MEDLINE]Related articlesFree article

Bloom's syndrome workshop focuses on the functional specificities of RecQ helicases.

Ellis NA, Sander M, Harris CC, Bohr VA.

Mech Ageing Dev. 2008 Nov;129(11):681-91.PMID: 19238688 [PubMed - indexed for MEDLINE]Related articles

Serum concentrations of cytokines and lung cancer survival in African Americans and Caucasians.

Enewold L, Mechanic LE, Bowman ED, Zheng YL, Yu Z, Trivers G, Alberg AJ, Harris CC.

Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):215-22.PMID: 19124500 [PubMed - indexed for MEDLINE]Related articles

p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation.

Brosh R, Shalgi R, Liran A, Landan G, Korotayev K, Nguyen GH, Enerly E, Johnsen H, Buganim Y, Solomon H, Goldstein I, Madar S, Goldfinger N, Børresen-Dale AL, Ginsberg D, Harris CC, Pilpel Y, Oren M, Rotter V.

Mol Syst Biol. 2008;4:229. Epub 2008 Nov 25.PMID: 19034270 [PubMed - indexed for MEDLINE]Related articlesFree article

The 23rd Aspen Cancer Conference: Mechanisms of toxicity, carcinogenesis, cancer prevention and cancer therapy 2008.

Sander M, Trump BF, Harris CC.

Mol Carcinog. 2009 May;48(5):465-78. No abstract available. PMID: 19009562 [PubMed - indexed for MEDLINE]Related articles

A novel ING2 isoform, ING2b, synergizes with ING2a to prevent cell cycle arrest and apoptosis.

Unoki M, Kumamoto K, Robles AI, Shen JC, Zheng ZM, Harris CC.

FEBS Lett. 2008 Nov 26;582(28):3868-74. Epub 2008 Oct 23.PMID: 18951897 [PubMed - indexed for MEDLINE]Related articles

Occupation, gender, race, and lung cancer.

Amr S, Wolpert B, Loffredo CA, Zheng YL, Shields PG, Jones R, Harris CC.

J Occup Environ Med. 2008 Oct;50(10):1167-75.PMID: 18849762 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide is a key component in inflammation-accelerated tumorigenesis.

Hussain SP, He P, Subleski J, Hofseth LJ, Trivers GE, Mechanic L, Hofseth AB, Bernard M, Schwank J, Nguyen G, Mathe E, Djurickovic D, Haines D, Weiss J, Back T, Gruys E, Laubach VE, Wiltrout RH, Harris CC.

Cancer Res. 2008 Sep 1;68(17):7130-6.PMID: 18757428 [PubMed - indexed for MEDLINE]Related articlesFree article

Advances in chemical carcinogenesis: a historical review and prospective.

Loeb LA, Harris CC.

Cancer Res. 2008 Sep 1;68(17):6863-72. Review. No abstract available. PMID: 18757397 [PubMed - indexed for MEDLINE]Related articlesFree article

Laser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events associated with mutated EGFR compared with wild type.

VanMeter AJ, Rodriguez AS, Bowman ED, Jen J, Harris CC, Deng J, Calvert VS, Silvestri A, Fredolini C, Chandhoke V, Petricoin EF 3rd, Liotta LA, Espina V.

Mol Cell Proteomics. 2008 Oct;7(10):1902-24. Epub 2008 Aug 6.PMID: 18687633 [PubMed - indexed for MEDLINE]Related articlesFree article

The reemergence of nitric oxide and cancer.

Wink DA, Ridnour LA, Hussain SP, Harris CC.

Nitric Oxide. 2008 Sep;19(2):65-7. Review. No abstract available. PMID: 18638716 [PubMed - indexed for MEDLINE]Related articlesFree article

Manganese superoxide dismutase gene coding region polymorphisms lack clinical incidence in general population.

Martin RC, Barker DF, Doll MA, Pine SR, Mechanic L, Bowman ED, Harris CC, Hein DW.

DNA Cell Biol. 2008 Jun;27(6):321-3.PMID: 18466086 [PubMed - indexed for MEDLINE]Related articlesFree article

Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence.

Kumamoto K, Spillare EA, Fujita K, Horikawa I, Yamashita T, Appella E, Nagashima M, Takenoshita S, Yokota J, Harris CC.

Cancer Res. 2008 May 1;68(9):3193-203.PMID: 18451145 [PubMed - indexed for MEDLINE]Related articlesFree article

The chemical biology of nitric oxide: implications in cellular signaling.

Thomas DD, Ridnour LA, Isenberg JS, Flores-Santana W, Switzer CH, Donzelli S, Hussain P, Vecoli C, Paolocci N, Ambs S, Colton CA, Harris CC, Roberts DD, Wink DA.

Free Radic Biol Med. 2008 Jul 1;45(1):18-31. Epub 2008 Apr 4. Review.PMID: 18439435 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphism Interaction Analysis (PIA): a method for investigating complex gene-gene interactions.

Mechanic LE, Luke BT, Goodman JE, Chanock SJ, Harris CC.

BMC Bioinformatics. 2008 Mar 6;9:146.PMID: 18325117 [PubMed - indexed for MEDLINE]Related articlesFree article

The 20th Aspen Cancer Conference: Mechanisms of Toxicity, Carcinogenesis, Cancer Prevention, and Cancer Therapy 2005.

Sander M, Trump BF, Harris CC, Tennant RW.

Mol Carcinog. 2008 Sep;47(9):707-32. No abstract available. PMID: 18286481 [PubMed - indexed for MEDLINE]Related articlesFree article

MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma.

Schetter AJ, Leung SY, Sohn JJ, Zanetti KA, Bowman ED, Yanaihara N, Yuen ST, Chan TL, Kwong DL, Au GK, Liu CG, Calin GA, Croce CM, Harris CC.

JAMA. 2008 Jan 30;299(4):425-36.PMID: 18230780 [PubMed - indexed for MEDLINE]Related articlesFree article

The twenty-second Aspen Cancer Conference: Mechanisms of Toxicity, Carcinogenesis, Cancer Prevention, and Cancer Therapy, 2007.

Sander M, Slaga TJ, Trump BF, Harris CC.

Mol Carcinog. 2008 Jul;47(7):554-71. No abstract available. PMID: 18092321 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional diversity of human protection of telomeres 1 isoforms in telomere protection and cellular senescence.

Yang Q, Zhang R, Horikawa I, Fujita K, Afshar Y, Kokko A, Laiho P, Aaltonen LA, Harris CC.

Cancer Res. 2007 Dec 15;67(24):11677-86.PMID: 18089797 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression and localization of Werner syndrome protein is modulated by SIRT1 and PML.

Vaitiekunaite R, Butkiewicz D, Krześniak M, Przybyłek M, Gryc A, Snietura M, Benedyk M, Harris CC, Rusin M.

Mech Ageing Dev. 2007 Nov-Dec;128(11-12):650-61. Epub 2007 Oct 2.PMID: 17996922 [PubMed - indexed for MEDLINE]Related articles

Inflammation and cancer: an ancient link with novel potentials.

Hussain SP, Harris CC.

Int J Cancer. 2007 Dec 1;121(11):2373-80. Review.PMID: 17893866 [PubMed - indexed for MEDLINE]Related articles

Lung cancer survival and functional polymorphisms in MBL2, an innate-immunity gene.

Pine SR, Mechanic LE, Ambs S, Bowman ED, Chanock SJ, Loffredo C, Shields PG, Harris CC.

J Natl Cancer Inst. 2007 Sep 19;99(18):1401-9. Epub 2007 Sep 11.PMID: 17848669 [PubMed - indexed for MEDLINE]Related articlesFree article

WNT10B functional dualism: beta-catenin/Tcf-dependent growth promotion or independent suppression with deregulated expression in cancer.

Yoshikawa H, Matsubara K, Zhou X, Okamura S, Kubo T, Murase Y, Shikauchi Y, Esteller M, Herman JG, Wei Wang X, Harris CC.

Mol Biol Cell. 2007 Nov;18(11):4292-303. Epub 2007 Aug 29.PMID: 17761539 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of a cytokine gene expression signature in lung adenocarcinoma and the surrounding tissue as a prognostic classifier.

Seike M, Yanaihara N, Bowman ED, Zanetti KA, Budhu A, Kumamoto K, Mechanic LE, Matsumoto S, Yokota J, Shibata T, Sugimura H, Gemma A, Kudoh S, Wang XW, Harris CC.

J Natl Cancer Inst. 2007 Aug 15;99(16):1257-69. Epub 2007 Aug 8.PMID: 17686824 [PubMed - indexed for MEDLINE]Related articlesFree article

Correlation of N-myc downstream-regulated gene 1 expression with clinical outcomes of colorectal cancer patients of different race/ethnicity.

Koshiji M, Kumamoto K, Morimura K, Utsumi Y, Aizawa M, Hoshino M, Ohki S, Takenoshita S, Costa M, Commes T, Piquemal D, Harris CC, Tchou-Wong KM.

World J Gastroenterol. 2007 May 28;13(20):2803-10.PMID: 17569115 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular characterization and cell-specific expression of an ion transport peptide in the tobacco hornworm, Manduca sexta.

Drexler AL, Harris CC, dela Pena MG, Asuncion-Uchi M, Chung S, Webster S, Fuse M.

Cell Tissue Res. 2007 Aug;329(2):391-408. Epub 2007 Apr 21.PMID: 17450383 [PubMed - indexed for MEDLINE]Related articles

Induction of a unique gene expression profile in primary human hepatocytes by hepatitis C virus core, NS3 and NS5A proteins.

Budhu A, Chen Y, Kim JW, Forgues M, Valerie K, Harris CC, Wang XW.

Carcinogenesis. 2007 Jul;28(7):1552-60. Epub 2007 Apr 2.PMID: 17404395 [PubMed - indexed for MEDLINE]Related articlesFree article

TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer.

Hussain SP, Schwank J, Staib F, Wang XW, Harris CC.

Oncogene. 2007 Apr 2;26(15):2166-76. Review.PMID: 17401425 [PubMed - indexed for MEDLINE]Related articles

Inhibitor of growth 4 suppresses cell spreading and cell migration by interacting with a novel binding partner, liprin alpha1.

Shen JC, Unoki M, Ythier D, Duperray A, Varticovski L, Kumamoto K, Pedeux R, Harris CC.

Cancer Res. 2007 Mar 15;67(6):2552-8.PMID: 17363573 [PubMed - indexed for MEDLINE]Related articlesFree article

Common genetic variation in TP53 is associated with lung cancer risk and prognosis in African Americans and somatic mutations in lung tumors.

Mechanic LE, Bowman ED, Welsh JA, Khan MA, Hagiwara N, Enewold L, Shields PG, Burdette L, Chanock S, Harris CC.

Cancer Epidemiol Biomarkers Prev. 2007 Feb;16(2):214-22.PMID: 17301252 [PubMed - indexed for MEDLINE]Related articlesFree article

The Twenty-First Aspen Cancer Conference: Mechanisms of Toxicity, Carcinogenesis, Cancer Prevention, and Cancer Therapy, 2006.

Sander M, Trump BF, Harris CC.

Mol Carcinog. 2007 Jun;46(6):415-35. No abstract available. PMID: 17186539 [PubMed - indexed for MEDLINE]Related articles

Novel splice variants of ING4 and their possible roles in the regulation of cell growth and motility.

Unoki M, Shen JC, Zheng ZM, Harris CC.

J Biol Chem. 2006 Nov 10;281(45):34677-86. Epub 2006 Sep 13.PMID: 16973615 [PubMed - indexed for MEDLINE]Related articlesFree article

Japan-US Cooperative Cancer Research Seminar on molecular epidemiological characteristics of lung and colon cancer development among atomic-bomb survivors, Bethesda, USA, February 23-24, 2006.

Nakachi K, Harris CC, Tahara E.

Cancer Sci. 2006 Nov;97(11):1279-82. Epub 2006 Sep 5. No abstract available. PMID: 16965394 [PubMed - indexed for MEDLINE]Related articles

Quantitative detection of p53 mutations in plasma DNA from tobacco smokers.

Hagiwara N, Mechanic LE, Trivers GE, Cawley HL, Taga M, Bowman ED, Kumamoto K, He P, Bernard M, Doja S, Miyashita M, Tajiri T, Sasajima K, Nomura T, Makino H, Takahashi K, Hussain SP, Harris CC.

Cancer Res. 2006 Aug 15;66(16):8309-17.PMID: 16912213 [PubMed - indexed for MEDLINE]Related articlesFree article

MDM2 SNP309 and SNP354 are not associated with lung cancer risk.

Pine SR, Mechanic LE, Bowman ED, Welsh JA, Chanock SC, Shields PG, Harris CC.

Cancer Epidemiol Biomarkers Prev. 2006 Aug;15(8):1559-61.PMID: 16896050 [PubMed - indexed for MEDLINE]Related articlesFree article

Superoxide fluxes limit nitric oxide-induced signaling.

Thomas DD, Ridnour LA, Espey MG, Donzelli S, Ambs S, Hussain SP, Harris CC, DeGraff W, Roberts DD, Mitchell JB, Wink DA.

J Biol Chem. 2006 Sep 8;281(36):25984-93. Epub 2006 Jul 7.PMID: 16829532 [PubMed - indexed for MEDLINE]Related articlesFree article