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Deletion of STAT-1 pancreatic islets protects against streptozotocin-induced diabetes and early graft failure but not against late rejection.
Callewaert HI, Gysemans CA, Ladrière L, D'Hertog W, Hagenbrock J, Overbergh L, Eizirik DL, Mathieu C.
Diabetes. 2007 Aug;56(8):2169-73. Epub 2007 May 1.PMID: 17473223 [PubMed - indexed for MEDLINE]Related articlesFree article
Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells.
Gysemans CA, Ladrière L, Callewaert H, Rasschaert J, Flamez D, Levy DE, Matthys P, Eizirik DL, Mathieu C.
Diabetes. 2005 Aug;54(8):2396-403.PMID: 16046307 [PubMed - indexed for MEDLINE]Related articlesFree article
1,25-Dihydroxyvitamin D3 modulates expression of chemokines and cytokines in pancreatic islets: implications for prevention of diabetes in nonobese diabetic mice.
Gysemans CA, Cardozo AK, Callewaert H, Giulietti A, Hulshagen L, Bouillon R, Eizirik DL, Mathieu C.
Endocrinology. 2005 Apr;146(4):1956-64. Epub 2005 Jan 6.PMID: 15637289 [PubMed - indexed for MEDLINE]Related articlesFree article
Dual role of interferon-gamma signalling pathway in sensitivity of pancreatic beta cells to immune destruction.
Gysemans CA, Pavlovic D, Bouillon R, Eizirik DL, Mathieu C.
Diabetologia. 2001 May;44(5):567-74.PMID: 11380074 [PubMed - indexed for MEDLINE]Related articles
Early graft failure of xenogeneic islets in NOD mice is accompanied by high levels of interleukin-1 and low levels of transforming growth factor-beta mRNA in the grafts.
Gysemans CA, Waer M, Valckx D, Laureys JM, Mihkalsky D, Bouillon R, Mathieu C.
Diabetes. 2000 Dec;49(12):1992-7.PMID: 11117999 [PubMed - indexed for MEDLINE]Related articlesFree article
The role of interferon regulatory factor-1 in cytokine-induced mRNA expression and cell death in murine pancreatic beta-cells.
Pavlovic D, Chen MC, Gysemans CA, Mathieu C, Eizirik DL.
Eur Cytokine Netw. 1999 Sep;10(3):403-12.PMID: 10477397 [PubMed - indexed for MEDLINE]Related articles
Sex difference in resistance to dexamethasone-induced apoptosis in NOD mice: treatment with 1,25(OH)2D3 restores defect.
Casteels KM, Gysemans CA, Waer M, Bouillon R, Laureys JM, Depovere J, Mathieu C.
Diabetes. 1998 Jul;47(7):1033-7.PMID: 9648825 [PubMed - indexed for MEDLINE]Related articlesFree article
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