PubMed

Glucose Generates Coincident Insulin and Somatostatin Pulses and Antisynchronous Glucagon Pulses from Human Pancreatic Islets.

Hellman B, Salehi A, Gylfe E, Dansk H, Grapengiesser E.

Endocrinology. 2009 Oct 9. [Epub ahead of print]PMID: 19819962 [PubMed - as supplied by publisher]Related articles

Oscillatory control of insulin secretion.

Tengholm A, Gylfe E.

Mol Cell Endocrinol. 2009 Jan 15;297(1-2):58-72. Epub 2008 Jul 26. Review.PMID: 18706473 [PubMed - indexed for MEDLINE]Related articles

Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion.

Dyachok O, Idevall-Hagren O, Sågetorp J, Tian G, Wuttke A, Arrieumerlou C, Akusjärvi G, Gylfe E, Tengholm A.

Cell Metab. 2008 Jul;8(1):26-37.PMID: 18590690 [PubMed - indexed for MEDLINE]Related articles

[Insulin oscillations--clinically important rhythm. Antidiabetics should increase the pulsative component of the insulin release]

Hellman B, Gylfe E, Grapengiesser E, Dansk H, Salehi A.

Lakartidningen. 2007 Aug 8-21;104(32-33):2236-9. Review. Swedish. No abstract available. PMID: 17822201 [PubMed - indexed for MEDLINE]Related articles

Glucose inhibits glucagon secretion by a direct effect on mouse pancreatic alpha cells.

Vieira E, Salehi A, Gylfe E.

Diabetologia. 2007 Feb;50(2):370-9. Epub 2006 Nov 29.PMID: 17136393 [PubMed - indexed for MEDLINE]Related articles

Paradoxical stimulation of glucagon secretion by high glucose concentrations.

Salehi A, Vieira E, Gylfe E.

Diabetes. 2006 Aug;55(8):2318-23.PMID: 16873696 [PubMed - indexed for MEDLINE]Related articlesFree article

Feedback activation of phospholipase C via intracellular mobilization and store-operated influx of Ca2+ in insulin-secreting beta-cells.

Thore S, Dyachok O, Gylfe E, Tengholm A.

J Cell Sci. 2005 Oct 1;118(Pt 19):4463-71. Epub 2005 Sep 13.PMID: 16159958 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase C modulates agonist-sensitive release of Ca2+ from internal stores in HEK293 cells overexpressing the calcium sensing receptor.

Sakwe AM, Rask L, Gylfe E.

J Biol Chem. 2005 Feb 11;280(6):4436-41. Epub 2004 Nov 30.PMID: 15572354 [PubMed - indexed for MEDLINE]Related articlesFree article

Ca(2+)-induced Ca(2+) release via inositol 1,4,5-trisphosphate receptors is amplified by protein kinase A and triggers exocytosis in pancreatic beta-cells.

Dyachok O, Gylfe E.

J Biol Chem. 2004 Oct 29;279(44):45455-61. Epub 2004 Aug 16.PMID: 15316011 [PubMed - indexed for MEDLINE]Related articlesFree article

Ca2+-induced Ca2+ release by activation of inositol 1,4,5-trisphosphate receptors in primary pancreatic beta-cells.

Dyachok O, Tufveson G, Gylfe E.

Cell Calcium. 2004 Jul;36(1):1-9.PMID: 15126051 [PubMed - indexed for MEDLINE]Related articles

A store-operated mechanism determines the activity of the electrically excitable glucagon-secreting pancreatic alpha-cell.

Liu YJ, Vieira E, Gylfe E.

Cell Calcium. 2004 Apr;35(4):357-65.PMID: 15036952 [PubMed - indexed for MEDLINE]Related articles

Involvement of alpha1 and beta-adrenoceptors in adrenaline stimulation of the glucagon-secreting mouse alpha-cell.

Vieira E, Liu YJ, Gylfe E.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Feb;369(2):179-83. Epub 2004 Jan 15.PMID: 14727006 [PubMed - indexed for MEDLINE]Related articles

The hepatitis C virus core protein modulates T cell responses by inducing spontaneous and altering T-cell receptor-triggered Ca2+ oscillations.

Bergqvist A, Sundström S, Dimberg LY, Gylfe E, Masucci MG.

J Biol Chem. 2003 May 23;278(21):18877-83. Epub 2003 Mar 13.PMID: 12639962 [PubMed - indexed for MEDLINE]Related articlesFree article

Stretch activation of Ca2+ transients in pancreatic beta cells by mobilization of intracellular stores.

Grapengiesser E, Gylfe E, Dansk H, Hellman B.

Pancreas. 2003 Jan;26(1):82-6.PMID: 12499922 [PubMed - indexed for MEDLINE]Related articles

Nitric oxide induces synchronous Ca2+ transients in pancreatic beta cells lacking contact.

Grapengiesser E, Gylfe E, Dansk H, Hellman B.

Pancreas. 2001 Nov;23(4):387-92.PMID: 11668208 [PubMed - indexed for MEDLINE]Related articles

Store-operated influx of Ca(2+) in pancreatic beta-cells exhibits graded dependence on the filling of the endoplasmic reticulum.

Dyachok O, Gylfe E.

J Cell Sci. 2001 Jun;114(Pt 11):2179-86.PMID: 11493653 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective glucose-dependent cytosolic Ca2+ handling in islets of GK and nSTZ rat models of type 2 diabetes.

Marie JC, Bailbé D, Gylfe E, Portha B.

J Endocrinol. 2001 Apr;169(1):169-76.PMID: 11250658 [PubMed - indexed for MEDLINE]Related articlesFree article

The endoplasmic reticulum is a glucose-modulated high-affinity sink for Ca2+ in mouse pancreatic beta-cells.

Tengholm A, Hellman B, Gylfe E.

J Physiol. 2001 Feb 1;530(Pt 3):533-40.PMID: 11158282 [PubMed - indexed for MEDLINE]Related articlesFree article

Signaling underlying pulsatile insulin secretion.

Gylfe E, Ahmed M, Bergsten P, Dansk H, Dyachok O, Eberhardson M, Grapengiesser E, Hellman B, Lin JM, Sundsten T, Tengholm A, Vieira E, Westerlund J.

Ups J Med Sci. 2000;105(2):35-51. Review. No abstract available. PMID: 11095104 [PubMed - indexed for MEDLINE]Related articles

Mobilization of Ca2+ stores in individual pancreatic beta-cells permeabilized or not with digitonin or alpha-toxin.

Tengholm A, Hellman B, Gylfe E.

Cell Calcium. 2000 Jan;27(1):43-51.PMID: 10726210 [PubMed - indexed for MEDLINE]Related articles

Oxytocin-induced oscillations of cytoplasmic Ca2+ in human myometrial cells.

Fu X, Liu YJ, Ciray N, Olovsson M, Ulmsten U, Gylfe E.

Acta Obstet Gynecol Scand. 2000 Mar;79(3):174-9.PMID: 10716297 [PubMed - indexed for MEDLINE]Related articles

Caffeine inhibits a low affinity but not a high affinity mechanism for cholecystokinin-evoked Ca2+ signalling and amylase release from guinea pig pancreatic acini.

Sjödin L, Gylfe E.

Naunyn Schmiedebergs Arch Pharmacol. 2000 Feb;361(2):113-9.PMID: 10685865 [PubMed - indexed for MEDLINE]Related articles

Glucose regulation of free Ca(2+) in the endoplasmic reticulum of mouse pancreatic beta cells.

Tengholm A, Hellman B, Gylfe E.

J Biol Chem. 1999 Dec 24;274(52):36883-90.PMID: 10601240 [PubMed - indexed for MEDLINE]Related articlesFree article

Ca2+ signaling in mouse pancreatic polypeptide cells.

Liu YJ, Hellman B, Gylfe E.

Endocrinology. 1999 Dec;140(12):5524-9.PMID: 10579315 [PubMed - indexed for MEDLINE]Related articlesFree article

Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells.

Lindholm CK, Gylfe E, Zhang W, Samelson LE, Welsh M.

J Biol Chem. 1999 Sep 24;274(39):28050-7.PMID: 10488157 [PubMed - indexed for MEDLINE]Related articlesFree article

Voltage-dependent entry and generation of slow Ca2+ oscillations in glucose-stimulated pancreatic beta-cells.

Dryselius S, Grapengiesser E, Hellman B, Gylfe E.

Am J Physiol. 1999 Mar;276(3 Pt 1):E512-8.PMID: 10070018 [PubMed - indexed for MEDLINE]Related articlesFree article

Synchronization of glucose-induced Ca2+ transients in pancreatic beta-cells by a diffusible factor.

Grapengiesser E, Gylfe E, Hellman B.

Biochem Biophys Res Commun. 1999 Jan 19;254(2):436-9.PMID: 9918856 [PubMed - indexed for MEDLINE]Related articles

Cell interactions with collagen matrices in vivo and in vitro depend on phosphatidylinositol 3-kinase and free cytoplasmic calcium.

Ahlén K, Berg A, Stiger F, Tengholm A, Siegbahn A, Gylfe E, Reed RK, Rubin K.

Cell Adhes Commun. 1998 Sep;5(6):461-73.PMID: 9791727 [PubMed - indexed for MEDLINE]Related articles

In situ characterization of nonmitochondrial Ca2+ stores in individual pancreatic beta-cells.

Tengholm A, Hagman C, Gylfe E, Hellman B.

Diabetes. 1998 Aug;47(8):1224-30.PMID: 9703321 [PubMed - indexed for MEDLINE]Related articlesFree article

Origin of slow and fast oscillations of Ca2+ in mouse pancreatic islets.

Liu YJ, Tengholm A, Grapengiesser E, Hellman B, Gylfe E.

J Physiol. 1998 Apr 15;508 ( Pt 2):471-81.PMID: 9508810 [PubMed - indexed for MEDLINE]Related articlesFree article

Generation of glucose-dependent slow oscillations of cytoplasmic Ca2+ in individual pancreatic beta cells.

Gylfe E, Grapengiesser E, Liu YJ, Dryselius S, Tengholm A, Eberhardson M.

Diabetes Metab. 1998 Feb;24(1):25-9. Review.PMID: 9534005 [PubMed - indexed for MEDLINE]Related articlesFree article

Store-operated Ca2+ entry in insulin-releasing pancreatic beta-cells.

Liu YJ, Gylfe E.

Cell Calcium. 1997 Oct;22(4):277-86.PMID: 9481478 [PubMed - indexed for MEDLINE]Related articles

Anisomycin and verapamil influence the action of progesterone on regulation of term human myometrial contractile activity.

Fu X, Moberg C, Bäckström T, Ulmsten U, Gylfe E.

Clin Endocrinol (Oxf). 1997 Sep;47(3):349-55.PMID: 9373458 [PubMed - indexed for MEDLINE]Related articles

Pulsatile insulin release from pancreatic islets with nonoscillatory elevation of cytoplasmic Ca2+.

Westerlund J, Gylfe E, Bergsten P.

J Clin Invest. 1997 Nov 15;100(10):2547-51.PMID: 9366569 [PubMed - indexed for MEDLINE]Related articlesFree article

Oscillatory signaling and insulin release in human pancreatic beta-cells exposed to strontium.

Hellman B, Gylfe E, Bergsten P, Grapengiesser E, Berts A, Liu YJ, Tengholm A, Westerlund J.

Endocrinology. 1997 Aug;138(8):3161-5.PMID: 9231763 [PubMed - indexed for MEDLINE]Related articlesFree article

Cholecystokinin-JMV-180 and pilocarpine are potent inhibitors of cholecystokinin and carbachol actions on guinea pig pancreatic acinar cells.

Sjödin L, Viitanen E, Gylfe E.

Naunyn Schmiedebergs Arch Pharmacol. 1997 May;355(5):631-7.PMID: 9151303 [PubMed - indexed for MEDLINE]Related articles

Oscillatory Ca2+ signaling in somatostatin-producing cells from the human pancreas.

Berts A, Liu YJ, Gylfe E, Hellman B.

Metabolism. 1997 Apr;46(4):366-9.PMID: 9109836 [PubMed - indexed for MEDLINE]Related articles

Cytoplasmic Ca2+ in glucagon-producing pancreatic alpha-cells exposed to carbachol and agents affecting Na+ fluxes.

Berts A, Gylfe E, Hellman B.

Endocrine. 1997 Feb;6(1):79-83.PMID: 9225120 [PubMed - indexed for MEDLINE]Related articles

Imaging of Ca(2+)-induced cytoplasmic Ca2+ responses in normal and pathological parathyroid cells.

Ridefelt P, Rastad J, Akerström G, Hellman P, Gylfe E.

Eur J Clin Invest. 1996 Dec;26(12):1166-70.PMID: 9013094 [PubMed - indexed for MEDLINE]Related articles

Crosstalk between the cAMP and inositol trisphosphate-signalling pathways in pancreatic beta-cells.

Liu YJ, Grapengiesser E, Gylfe E, Hellman B.

Arch Biochem Biophys. 1996 Oct 15;334(2):295-302.PMID: 8900404 [PubMed - indexed for MEDLINE]Related articles

Effects of calcium channel modulators on the regulation of cytoplasmic Ca2+ and hormone secretion of parathyroid cells.

Ridefelt P, Hellman P, Rastad J, Larsson R, Akerström G, Gylfe E.

Pharmacol Toxicol. 1996 Mar;78(3):147-53.PMID: 8882347 [PubMed - indexed for MEDLINE]Related articles

Suppression of Ca2+ oscillations in glucagon-producing alpha 2-cells by insulin/glucose and amino acids.

Berts A, Ball A, Gylfe E, Hellman B.

Biochim Biophys Acta. 1996 Feb 2;1310(2):212-6.PMID: 8611635 [PubMed - indexed for MEDLINE]Related articles

Glucose stimulation of somatostatin-producing islet cells involves oscillatory Ca2+ signaling.

Berts A, Ball A, Dryselius G, Gylfe E, Hellman B.

Endocrinology. 1996 Feb;137(2):693-7.PMID: 8593819 [PubMed - indexed for MEDLINE]Related articles

Ca(2+)-induced Ca2+ oscillations in parathyroid cells.

Ridefelt P, Björklund E, Akerström G, Olsson MJ, Rastad J, Gylfe E.

Biochem Biophys Res Commun. 1995 Oct 24;215(3):903-9.PMID: 7488059 [PubMed - indexed for MEDLINE]Related articles

Glucose induces oscillations of cytoplasmic Ca2+, Sr2+ and Ba2+ in pancreatic beta-cells without participation of the thapsigargin-sensitive store.

Liu YJ, Grapengiesser E, Gylfe E, Hellman B.

Cell Calcium. 1995 Aug;18(2):165-73.PMID: 7585893 [PubMed - indexed for MEDLINE]Related articles

Coincidence of early glucose-induced depolarization with lowering of cytoplasmic Ca2+ in mouse pancreatic beta-cells.

Chow RH, Lund PE, Löser S, Panten U, Gylfe E.

J Physiol. 1995 Jun 15;485 ( Pt 3):607-17.PMID: 7562604 [PubMed - indexed for MEDLINE]Related articlesFree article

Ca2+ oscillations in pancreatic islet cells secreting glucagon and somatostatin.

Berts A, Gylfe E, Hellman B.

Biochem Biophys Res Commun. 1995 Mar 17;208(2):644-9.PMID: 7695619 [PubMed - indexed for MEDLINE]Related articles

Effects of the antihypercalcemic drugs gallium nitrate and pamidronate on hormone release of pathologic human parathyroid cells.

Ridefelt P, Gylfe E, Akerström G, Rastad J.

Surgery. 1995 Jan;117(1):56-61.PMID: 7809837 [PubMed - indexed for MEDLINE]Related articles

Glucose-induced oscillations of Ba2+ in pancreatic beta-cells occur without involvement of intracellular mobilization.

Liu YJ, Grapengiesser E, Gylfe E, Hellman B.

Arch Biochem Biophys. 1994 Dec;315(2):387-92.PMID: 7986082 [PubMed - indexed for MEDLINE]Related articles

Variations in ATP-sensitive K+ channel activity provide evidence for inherent metabolic oscillations in pancreatic beta-cells.

Dryselius S, Lund PE, Gylfe E, Hellman B.

Biochem Biophys Res Commun. 1994 Nov 30;205(1):880-5.PMID: 7999126 [PubMed - indexed for MEDLINE]Related articles