PubMed

The worry about clopidogrel "nonresponsiveness": identification and treatment in the post-percutaneous coronary intervention patient.

Gurbel PA, Tantry US, Shuldiner AR.

JACC Cardiovasc Interv. 2009 Nov;2(11):1102-4. No abstract available. PMID: 19926051 [PubMed - in process]Related articles

Randomized Double-Blind Assessment of the ONSET and OFFSET of the Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Stable Coronary Artery Disease. Randomized Double-Blind Assessment of the ONSET and OFFSET of the Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Stable Cornonary Disease: The ONSET/OFFSET Study.

Gurbel PA, Bliden KP, Butler K, Tantry US, Gesheff T, Wei C, Teng R, Antonino MJ, Patil SB, Karunakaran A, Kereiakes DJ, Parris C, Purdy D, Wilson V, Ledley GS, Storey RF.

Circulation. 2009 Nov 18. [Epub ahead of print]PMID: 19923168 [PubMed - as supplied by publisher]Related articles

Platelet monitoring for PCI.

Tantry US, Gurbel PA.

Hamostaseologie. 2009 Sep;29(4):368-75.PMID: 19882080 [PubMed - in process]Related articles

The relation between platelet reactivity and glycemic control in diabetic patients with cardiovascular disease on maintenance aspirin and clopidogrel therapy.

Singla A, Antonino MJ, Bliden KP, Tantry US, Gurbel PA.

Am Heart J. 2009 Nov;158(5):784.e1-6.PMID: 19853698 [PubMed - in process]Related articles

The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to cyp 2c19*2 genotype: first experience in patients.

Gurbel PA, Bliden KP, Antonino MJ, Stephens G, Gretler DD, Jurek MM, Pakyz RE, Shuldiner AR, Conley PB, Tantry US.

J Thromb Haemost. 2009 Oct 11. [Epub ahead of print]PMID: 19817997 [PubMed - as supplied by publisher]Related articles

Expert consensus on treatment strategies in non- ST-segment elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention--an evidence-based review of clinical trial results and treatment guidelines from an emergency medicine perspective: report on a roundtable discussion.

Hoekstra J, Cohen M, Giugliano R, Granger CB, Gurbel PA, Hollander JE, Manoukian SV, Saucedo JF, Pollack CV Jr.

Am J Emerg Med. 2009 Jul;27(6):720-8. Review. No abstract available. PMID: 19757551 [PubMed - indexed for MEDLINE]Related articles

Antiplatelet resistance--fact or myth?

Gurbel PA, Tantry US.

Am Heart Hosp J. 2009 Summer;7(1):50-7. No abstract available. PMID: 19742434 [PubMed - in process]Related articlesFree article

Aspirin resistance.

Tantry US, Mahla E, Gurbel PA.

Prog Cardiovasc Dis. 2009 Sep-Oct;52(2):141-52. Review. No abstract available. PMID: 19732606 [PubMed - indexed for MEDLINE]Related articles

Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy.

Shuldiner AR, O'Connell JR, Bliden KP, Gandhi A, Ryan K, Horenstein RB, Damcott CM, Pakyz R, Tantry US, Gibson Q, Pollin TI, Post W, Parsa A, Mitchell BD, Faraday N, Herzog W, Gurbel PA.

JAMA. 2009 Aug 26;302(8):849-57.PMID: 19706858 [PubMed - indexed for MEDLINE]Related articles

Recent developments in clopidogrel pharmacology and their relation to clinical outcomes.

Gurbel PA, Antonino MJ, Tantry US.

Expert Opin Drug Metab Toxicol. 2009 Aug;5(8):989-1004. Review.PMID: 19575629 [PubMed - indexed for MEDLINE]Related articles

Effect of long-term clopidogrel treatment on platelet function and inflammation in patients undergoing coronary arterial stenting.

Antonino MJ, Mahla E, Bliden KP, Tantry US, Gurbel PA.

Am J Cardiol. 2009 Jun 1;103(11):1546-50. Epub 2009 Apr 8.PMID: 19463513 [PubMed - indexed for MEDLINE]Related articles

Peri-procedural platelet function and platelet inhibition in percutaneous coronary intervention.

Kereiakes DJ, Gurbel PA.

JACC Cardiovasc Interv. 2008 Apr;1(2):111-21. Review.PMID: 19463287 [PubMed - indexed for MEDLINE]Related articles

Antiplatelet effects of aspirin with phytosterols: Comparison with non-enteric coated aspirin alone.

Antonino MJ, Coppolecchia R, Mahla E, Bliden KP, Tantry US, Gurbel PA.

Thromb Res. 2009 May 14. [Epub ahead of print]PMID: 19446864 [PubMed - as supplied by publisher]Related articles

Response variability and the role of platelet function testing.

Gurbel PA, Mahla E, Antonino MJ, Tantry US.

J Invasive Cardiol. 2009 Apr;21(4):172-8. No abstract available. PMID: 19342756 [PubMed - in process]Related articlesFree article

The drug-drug interaction between proton pump inhibitors and clopidogrel.

Lau WC, Gurbel PA.

CMAJ. 2009 Mar 31;180(7):699-700. No abstract available. PMID: 19332744 [PubMed - indexed for MEDLINE]Related articlesFree article

Point-of-care platelet function analysis ready for prime time?

Mahla E, Antonino MJ, Tantry US, Gurbel PA.

J Am Coll Cardiol. 2009 Mar 10;53(10):857-9. No abstract available. PMID: 19264242 [PubMed - indexed for MEDLINE]Related articles

The link between heightened thrombogenicity and inflammation: pre-procedure characterization of the patient at high risk for recurrent events after stenting.

Gurbel PA, Bliden KP, Kreutz RP, Dichiara J, Antonino MJ, Tantry US.

Platelets. 2009 Mar;20(2):97-104.PMID: 19235051 [PubMed - indexed for MEDLINE]Related articles

Bivalirudin and clopidogrel with and without eptifibatide for elective stenting: effects on platelet function, thrombelastographic indexes, and their relation to periprocedural infarction results of the CLEAR PLATELETS-2 (Clopidogrel with Eptifibatide to Arrest the Reactivity of Platelets) study.

Gurbel PA, Bliden KP, Saucedo JF, Suarez TA, DiChiara J, Antonino MJ, Mahla E, Singla A, Herzog WR, Bassi AK, Hennebry TA, Gesheff TB, Tantry US.

J Am Coll Cardiol. 2009 Feb 24;53(8):648-57.PMID: 19232896 [PubMed - indexed for MEDLINE]Related articles

Advances in antiplatelet therapy: agents in clinical development.

Angiolillo DJ, Bhatt DL, Gurbel PA, Jennings LK.

Am J Cardiol. 2009 Feb 2;103(3 Suppl):40A-51A. Review.PMID: 19166712 [PubMed - indexed for MEDLINE]Related articles

Selecting optimal antiplatelet therapy based on platelet function monitoring in patients with coronary artery disease.

Gurbel PA, Tantry US.

Curr Treat Options Cardiovasc Med. 2009 Feb;11(1):22-32.PMID: 19141258 [PubMed - in process]Related articles

The rationale for and comparisons of different antiplatelet treatments in acute coronary syndrome.

Gurbel PA, Tantry US.

J Interv Cardiol. 2008 Dec;21 Suppl 1:S10-7. Review.PMID: 19090932 [PubMed - indexed for MEDLINE]Related articles

Platelet reactivity to adenosine diphosphate and long-term ischemic event occurrence following percutaneous coronary intervention: a potential antiplatelet therapeutic target.

Gurbel PA, Antonino MJ, Bliden KP, Dichiara J, Suarez TA, Singla A, Tantry US.

Platelets. 2008 Dec;19(8):595-604.PMID: 19012177 [PubMed - indexed for MEDLINE]Related articles

Dark chocolate effect on platelet activity, C-reactive protein and lipid profile: a pilot study.

Hamed MS, Gambert S, Bliden KP, Bailon O, Singla A, Antonino MJ, Hamed F, Tantry US, Gurbel PA.

South Med J. 2008 Dec;101(12):1203-8. Erratum in: South Med J. 2009 Mar;102(3):332. Anand, Singla [corrected to Singla, Anand]. PMID: 19005437 [PubMed - indexed for MEDLINE]Related articles

Treatment strategies in non-ST-elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention: an evidence-based review of clinical trial results and treatment guidelines: report on a roundtable discussion.

Cohen M, Hoekstra J, Giugliano R, Granger CB, Gurbel PA, Hollander JE, Manoukian SV, Pollack CV Jr, Saucedo JF.

J Interv Cardiol. 2008 Aug;21(4):283-99. Review.PMID: 18754964 [PubMed - indexed for MEDLINE]Related articles

The association of cigarette smoking with enhanced platelet inhibition by clopidogrel.

Bliden KP, Dichiara J, Lawal L, Singla A, Antonino MJ, Baker BA, Bailey WL, Tantry US, Gurbel PA.

J Am Coll Cardiol. 2008 Aug 12;52(7):531-3.PMID: 18687246 [PubMed - indexed for MEDLINE]Related articles

Antiplatelet treatment of cardiovascular disease: a translational research perspective.

Gurbel PA, Antonino MJ, Tantry US.

Pol Arch Med Wewn. 2008 May;118(5):289-97. Review.PMID: 18619179 [PubMed - indexed for MEDLINE]Related articlesFree article

Race and sex differences in thrombogenicity: risk of ischemic events following coronary stenting.

Gurbel PA, Bliden KP, Cohen E, Navickas IA, Singla A, Antonino MJ, Fissha M, Kreutz RP, Bassi AK, Tantry US.

Blood Coagul Fibrinolysis. 2008 Jun;19(4):268-75.PMID: 18469547 [PubMed - indexed for MEDLINE]Related articles

Prasugrel, a third generation thienopyridine and potent platelet inhibitor.

Gurbel PA, Tantry US.

Curr Opin Investig Drugs. 2008 Mar;9(3):324-36. Review.PMID: 18311669 [PubMed - indexed for MEDLINE]Related articles

Diagnostics for aspirin resistance.

Gurbel PA, Bilden KP, Tantry US.

Mol Diagn Ther. 2008;12(1):55-6. No abstract available. PMID: 18288883 [PubMed - indexed for MEDLINE]Related articles

Relationship between age and platelet activation in patients with stable and unstable angina.

Gilstad JR, Gurbel PA, Andersen RE.

Arch Gerontol Geriatr. 2009 Mar-Apr;48(2):155-9. Epub 2008 Feb 20.PMID: 18282622 [PubMed - indexed for MEDLINE]Related articles

Omeprazole: a possible new candidate influencing the antiplatelet effect of clopidogrel.

Gurbel PA, Lau WC, Tantry US.

J Am Coll Cardiol. 2008 Jan 22;51(3):261-3. No abstract available. PMID: 18206733 [PubMed - indexed for MEDLINE]Related articles

Biomarker analysis by fluorokine multianalyte profiling distinguishes patients requiring intervention from patients with long-term quiescent coronary artery disease: a potential approach to identify atherosclerotic disease progression.

Gurbel PA, Kreutz RP, Bliden KP, DiChiara J, Tantry US.

Am Heart J. 2008 Jan;155(1):56-61. Epub 2007 Oct 17.PMID: 18082490 [PubMed - indexed for MEDLINE]Related articles

[The role of clopidogrel in cardiovascular diseases]

Gurbel PA, Tantry US.

Pol Arch Med Wewn. 2007 May-Jun;117(5-6):207-9. Polish. No abstract available. PMID: 18030868 [PubMed - indexed for MEDLINE]Related articlesFree article

Antiplatelet therapy after implantation of drug-eluting stents: duration, resistance, alternatives, and management of surgical patients.

Gurbel PA, DiChiara J, Tantry US.

Am J Cardiol. 2007 Oct 22;100(8B):18M-25M. Review.PMID: 17950828 [PubMed - indexed for MEDLINE]Related articles

Inflammatory changes during the 'common cold' are associated with platelet activation and increased reactivity of platelets to agonists.

Kreutz RP, Tantry US, Bliden KP, Gurbel PA.

Blood Coagul Fibrinolysis. 2007 Dec;18(8):713-8.PMID: 17982310 [PubMed - indexed for MEDLINE]Related articles

Platelet function monitoring in patients with coronary artery disease.

Gurbel PA, Becker RC, Mann KG, Steinhubl SR, Michelson AD.

J Am Coll Cardiol. 2007 Nov 6;50(19):1822-34. Epub 2007 Oct 23. Review.PMID: 17980247 [PubMed - indexed for MEDLINE]Related articles

Post-coronary intervention recurrent ischemia in the presence of adequate platelet inhibition by dual antiplatelet therapy: what are we overlooking?

Gurbel PA, Bliden KP, Navickas I, Cohen E, Tantry US.

J Thromb Haemost. 2007 Nov;5(11):2300-1. No abstract available. PMID: 17958747 [PubMed - indexed for MEDLINE]Related articles

The effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study.

DiChiara J, Bliden KP, Tantry US, Hamed MS, Antonino MJ, Suarez TA, Bailon O, Singla A, Gurbel PA.

Diabetes. 2007 Dec;56(12):3014-9. Epub 2007 Sep 11.PMID: 17848625 [PubMed - indexed for MEDLINE]Related articlesFree article

Platelet function measured by VerifyNow identifies generalized high platelet reactivity in aspirin treated patients.

Dichiara J, Bliden KP, Tantry US, Chaganti SK, Kreutz RP, Gesheff TB, Kreutz Y, Gurbel PA.

Platelets. 2007 Sep;18(6):414-23.PMID: 17763150 [PubMed - indexed for MEDLINE]Related articles

Stent thrombosis associated with first-generation drug-eluting stents: issues with antiplatelet therapy.

Gurbel PA, Kandzari DE.

Neth Heart J. 2007;15(4):148-50.PMID: 17612675 [PubMed - in process]Related articlesFree article

Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study.

Gurbel PA, Bliden KP, DiChiara J, Newcomer J, Weng W, Neerchal NK, Gesheff T, Chaganti SK, Etherington A, Tantry US.

Circulation. 2007 Jun 26;115(25):3156-64. Epub 2007 Jun 11.PMID: 17562955 [PubMed - indexed for MEDLINE]Related articlesFree article

Stent thrombosis: role of compliance and nonresponsiveness to antiplatelet therapy.

Gurbel PA, Tantry US.

Rev Cardiovasc Med. 2007;8 Suppl 1:S19-26. Review.PMID: 17401307 [PubMed - indexed for MEDLINE]Related articles

Assessment of clopidogrel responsiveness: measurements of maximum platelet aggregation, final platelet aggregation and their correlation with vasodilator-stimulated phosphoprotein in resistant patients.

Gurbel PA, Bliden KP, Etherington A, Tantry US.

Thromb Res. 2007;121(1):107-15. Epub 2007 Apr 2.PMID: 17400283 [PubMed - indexed for MEDLINE]Related articles

Increased risk in patients with high platelet aggregation receiving chronic clopidogrel therapy undergoing percutaneous coronary intervention: is the current antiplatelet therapy adequate?

Bliden KP, DiChiara J, Tantry US, Bassi AK, Chaganti SK, Gurbel PA.

J Am Coll Cardiol. 2007 Feb 13;49(6):657-66. Epub 2007 Jan 26.PMID: 17291930 [PubMed - indexed for MEDLINE]Related articles

AZD6140.

Tantry US, Bliden KP, Gurbel PA.

Expert Opin Investig Drugs. 2007 Feb;16(2):225-9. Review.PMID: 17243942 [PubMed - indexed for MEDLINE]Related articles

The relationship of platelet reactivity to the occurrence of post-stenting ischemic events: emergence of a new cardiovascular risk factor.

Gurbel PA.

Rev Cardiovasc Med. 2006;7 Suppl 4:S20-8. Review.PMID: 17224887 [PubMed - indexed for MEDLINE]Related articles

Comparison of zotarolimus-eluting and sirolimus-eluting stents in patients with native coronary artery disease: a randomized controlled trial.

Kandzari DE, Leon MB, Popma JJ, Fitzgerald PJ, O'Shaughnessy C, Ball MW, Turco M, Applegate RJ, Gurbel PA, Midei MG, Badre SS, Mauri L, Thompson KP, LeNarz LA, Kuntz RE; ENDEAVOR III Investigators.

J Am Coll Cardiol. 2006 Dec 19;48(12):2440-7. Epub 2006 Nov 28.PMID: 17174180 [PubMed - indexed for MEDLINE]Related articles

Effect of clopidogrel with and without eptifibatide on tumor necrosis factor-alpha and C-reactive protein release after elective stenting: results from the CLEAR PLATELETS 1b study.

Gurbel PA, Bliden KP, Tantry US.

J Am Coll Cardiol. 2006 Dec 5;48(11):2186-91.PMID: 17161243 [PubMed - indexed for MEDLINE]Related articles

Clopidogrel resistance?

Gurbel PA, Tantry US.

Thromb Res. 2007;120(3):311-21. Epub 2006 Nov 14. Review.PMID: 17109936 [PubMed - indexed for MEDLINE]Related articles

Prasugrel.

Tantry US, Bliden KP, Gurbel PA.

Expert Opin Investig Drugs. 2006 Dec;15(12):1627-33. Review.PMID: 17107286 [PubMed - indexed for MEDLINE]Related articles