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    Results: 28

    1.

    The development of hepatic fibrosis occurs normally in AMPK deficient mice.

    da Silva Morais A, Abarca-Quinones J, Guigas B, Viollet B, Stärkel P, Horsmans Y, Leclercq IA.

    Clin Sci (Lond). 2009 Oct 26. [Epub ahead of print]PMID: 19852755 [PubMed - as supplied by publisher]Related articles

    2.

    AMPK: Lessons from transgenic and knockout animals.

    Viollet B, Athea Y, Mounier R, Guigas B, Zarrinpashneh E, Horman S, Lantier L, Hebrard S, Devin-Leclerc J, Beauloye C, Foretz M, Andreelli F, Ventura-Clapier R, Bertrand L.

    Front Biosci. 2009 Jan 1;14:19-44. Review.PMID: 19273052 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives.

    Viollet B, Guigas B, Leclerc J, Hébrard S, Lantier L, Mounier R, Andreelli F, Foretz M.

    Acta Physiol (Oxf). 2009 May;196(1):81-98. Epub 2009 Feb 19.PMID: 19245656 [PubMed - in process]Related articles

    4.

    Prevention of steatohepatitis by pioglitazone: implication of adiponectin-dependent inhibition of SREBP-1c and inflammation.

    Da Silva Morais A, Lebrun V, Abarca-Quinones J, Brichard S, Hue L, Guigas B, Viollet B, Leclercq IA.

    J Hepatol. 2009 Mar;50(3):489-500. Epub 2008 Dec 26.PMID: 19155087 [PubMed - indexed for MEDLINE]Related articles

    5.

    High expression of thyroid hormone receptors and mitochondrial glycerol-3-phosphate dehydrogenase in the liver is linked to enhanced fatty acid oxidation in Lou/C, a rat strain resistant to obesity.

    Taleux N, Guigas B, Dubouchaud H, Moreno M, Weitzel JM, Goglia F, Favier R, Leverve XM.

    J Biol Chem. 2009 Feb 13;284(7):4308-16. Epub 2008 Dec 2.PMID: 19049970 [PubMed - indexed for MEDLINE]Related articles

    6.

    Beyond AICA riboside: in search of new specific AMP-activated protein kinase activators.

    Guigas B, Sakamoto K, Taleux N, Reyna SM, Musi N, Viollet B, Hue L.

    IUBMB Life. 2009 Jan;61(1):18-26. Review.PMID: 18798311 [PubMed - indexed for MEDLINE]Related articles

    7.

    No lack of contraction-induced AMPK activation and glucose uptake in fast-twitch muscles from adenylate kinase-1 knockout mice.

    Guigas B.

    Acta Physiol (Oxf). 2008 Mar;192(3):337. No abstract available. PMID: 18271795 [PubMed - indexed for MEDLINE]Related articles

    8.

    Liver mitochondrial properties from the obesity-resistant Lou/C rat.

    Lacraz G, Couturier K, Taleux N, Servais S, Sibille B, Letexier D, Guigas B, Dubouchaud H, Leverve X, Favier R.

    Int J Obes (Lond). 2008 Apr;32(4):629-38. Epub 2008 Jan 15.PMID: 18197185 [PubMed - indexed for MEDLINE]Related articles

    9.

    Lack of starvation-induced activation of AMP-activated protein kinase in the hypothalamus of the Lou/C rats resistant to obesity.

    Taleux N, De Potter I, Deransart C, Lacraz G, Favier R, Leverve XM, Hue L, Guigas B.

    Int J Obes (Lond). 2008 Apr;32(4):639-47. Epub 2007 Dec 4.PMID: 18059408 [PubMed - indexed for MEDLINE]Related articles

    10.

    Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons.

    El-Mir MY, Detaille D, R-Villanueva G, Delgado-Esteban M, Guigas B, Attia S, Fontaine E, Almeida A, Leverve X.

    J Mol Neurosci. 2008;34(1):77-87. Epub 2007 Nov 27.PMID: 18040888 [PubMed - indexed for MEDLINE]Related articles

    11.

    The flavonoid silibinin decreases glucose-6-phosphate hydrolysis in perfused rat hepatocytes by an inhibitory effect on glucose-6-phosphatase.

    Guigas B, Naboulsi R, Villanueva GR, Taleux N, Lopez-Novoa JM, Leverve XM, El-Mir MY.

    Cell Physiol Biochem. 2007;20(6):925-34. Erratum in: Cell Physiol Biochem. 2008;21(5-6):500. PMID: 17982275 [PubMed - indexed for MEDLINE]Related articles

    12.

    Cryopreservation of human hepatocytes alters the mitochondrial respiratory chain complex 1.

    Stéphenne X, Najimi M, Ngoc DK, Smets F, Hue L, Guigas B, Sokal EM.

    Cell Transplant. 2007;16(4):409-19.PMID: 17658131 [PubMed - indexed for MEDLINE]Related articles

    13.

    Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle.

    Krämer DK, Al-Khalili L, Guigas B, Leng Y, Garcia-Roves PM, Krook A.

    J Biol Chem. 2007 Jul 6;282(27):19313-20. Epub 2007 May 11.PMID: 17500064 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside.

    Guigas B, Taleux N, Foretz M, Detaille D, Andreelli F, Viollet B, Hue L.

    Biochem J. 2007 Jun 15;404(3):499-507.PMID: 17324122 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin.

    Batandier C, Guigas B, Detaille D, El-Mir MY, Fontaine E, Rigoulet M, Leverve XM.

    J Bioenerg Biomembr. 2006 Feb;38(1):33-42.PMID: 16732470 [PubMed - indexed for MEDLINE]Related articles

    16.

    Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders.

    Viollet B, Foretz M, Guigas B, Horman S, Dentin R, Bertrand L, Hue L, Andreelli F.

    J Physiol. 2006 Jul 1;574(Pt 1):41-53. Epub 2006 Apr 27. Review.PMID: 16644802 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    [Regulation of energy metabolism by AMPK: a novel therapeutic approach for the treatment of metabolic and cardiovascular diseases]

    Foretz M, Taleux N, Guigas B, Horman S, Beauloye C, Andreelli F, Bertrand L, Viollet B.

    Med Sci (Paris). 2006 Apr;22(4):381-8. Review. French. PMID: 16597407 [PubMed - indexed for MEDLINE]Related articles

    18.

    [From cancer to diabetes treatment : the tumor suppressor LKB1 as a new pharmacological target]

    Foretz M, Guigas B, Viollet B.

    Med Sci (Paris). 2006 Apr;22(4):348-50. French. No abstract available. PMID: 16597397 [PubMed - indexed for MEDLINE]Related articles

    19.

    5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and metformin inhibit hepatic glucose phosphorylation by an AMP-activated protein kinase-independent effect on glucokinase translocation.

    Guigas B, Bertrand L, Taleux N, Foretz M, Wiernsperger N, Vertommen D, Andreelli F, Viollet B, Hue L.

    Diabetes. 2006 Apr;55(4):865-74.PMID: 16567505 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B.

    Bertrand L, Ginion A, Beauloye C, Hebert AD, Guigas B, Hue L, Vanoverschelde JL.

    Am J Physiol Heart Circ Physiol. 2006 Jul;291(1):H239-50. Epub 2006 Feb 17.PMID: 16489105 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation.

    Gresh L, Bourachot B, Reimann A, Guigas B, Fiette L, Garbay S, Muchardt C, Hue L, Pontoglio M, Yaniv M, Klochendler-Yeivin A.

    EMBO J. 2005 Sep 21;24(18):3313-24. Epub 2005 Sep 1.PMID: 16138077 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    Metformin prevents high-glucose-induced endothelial cell death through a mitochondrial permeability transition-dependent process.

    Detaille D, Guigas B, Chauvin C, Batandier C, Fontaine E, Wiernsperger N, Leverve X.

    Diabetes. 2005 Jul;54(7):2179-87.PMID: 15983220 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    Fluid-regulatory hormone responses during cycling exercise in acute hypobaric hypoxia.

    Bocqueraz O, Koulmann N, Guigas B, Jimenez C, Melin B.

    Med Sci Sports Exerc. 2004 Oct;36(10):1730-6.PMID: 15595294 [PubMed - indexed for MEDLINE]Related articles

    24.

    Metabolic and hormonal responses to exercise in the anti-obese Lou/C rats.

    Couturier K, Servais S, Koubi H, Sempore B, Cottet-Emard JM, Guigas B, Lavoie JM, Favier R.

    Int J Obes Relat Metab Disord. 2004 Aug;28(8):972-8.PMID: 15211361 [PubMed - indexed for MEDLINE]Related articles

    25.

    Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study.

    Guigas B, Detaille D, Chauvin C, Batandier C, De Oliveira F, Fontaine E, Leverve X.

    Biochem J. 2004 Sep 15;382(Pt 3):877-84.PMID: 15175014 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    Mitochondrial metabolism and type-2 diabetes: a specific target of metformin.

    Leverve XM, Guigas B, Detaille D, Batandier C, Koceir EA, Chauvin C, Fontaine E, Wiernsperger NF.

    Diabetes Metab. 2003 Sep;29(4 Pt 2):6S88-94. Review.PMID: 14502105 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.

    Obligatory role of membrane events in the regulatory effect of metformin on the respiratory chain function.

    Detaille D, Guigas B, Leverve X, Wiernsperger N, Devos P.

    Biochem Pharmacol. 2002 Apr 1;63(7):1259-72.PMID: 11960602 [PubMed - indexed for MEDLINE]Related articles

    28.

    Glucose 6-phosphate hydrolysis is activated by glucagon in a low temperature-sensitive manner.

    Ichai C, Guignot L, El-Mir MY, Nogueira V, Guigas B, Chauvin C, Fontaine E, Mithieux G, Leverve XM.

    J Biol Chem. 2001 Jul 27;276(30):28126-33. Epub 2001 May 22.PMID: 11371550 [PubMed - indexed for MEDLINE]Related articlesFree article

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