PubMed

c-Abl tyrosine kinase interacts with MAVS and regulates innate immune response.

Song T, Wei C, Zheng Z, Xu Y, Cheng X, Yuan Y, Guan K, Zhang Y, Ma Q, Shi W, Zhong H.

FEBS Lett. 2009 Nov 13. [Epub ahead of print]PMID: 19914245 [PubMed - as supplied by publisher]Related articles

Mst out and HCC in.

Zhao B, Lei Q, Guan KL.

Cancer Cell. 2009 Nov 6;16(5):363-4.PMID: 19878866 [PubMed - in process]Related articles

Amino acid signaling to TOR activation: Vam6 functioning as a Gtr1 GEF.

Li L, Guan KL.

Mol Cell. 2009 Sep 11;35(5):543-5.PMID: 19748348 [PubMed - indexed for MEDLINE]Related articles

Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules.

Dressel R, Guan K, Nolte J, Elsner L, Monecke S, Nayernia K, Hasenfuss G, Engel W.

Biol Direct. 2009 Aug 28;4:31.PMID: 19715575 [PubMed - in process]Related articlesFree article

Critical roles for the TSC-mTOR pathway in {beta}-cell function.

Mori H, Inoki K, Opland D, Muenzberg H, Villanueva EC, Faouzi M, Ikenoue T, Kwiatkowski D, Macdougald OA, Myers Jr MG, Guan KL.

Am J Physiol Endocrinol Metab. 2009 Aug 18. [Epub ahead of print]PMID: 19690069 [PubMed - as supplied by publisher]Related articles

Comparison and evaluation of several Dermatophagoides pteronyssinus allergen extracts for skin prick test.

Sun JL, Wang RQ, Yin J, Wang LL, Zhang HY, Li H, Zhi YX, Wen LP, Guan K, Gu JQ, He HJ, Zhao Y, Zhang W, Sun GQ.

Chin Med Sci J. 2009 Jun;24(2):86-90.PMID: 19618604 [PubMed - indexed for MEDLINE]Related articles

[Clinical significance of serum levels of endostatin in patients with clear cell renal cell carcinoma]

Guan KP, Xiao ZD, Wang D, Shi HZ, Guan YY, Lu L, Han SJ, Li CL.

Zhonghua Wai Ke Za Zhi. 2009 May 15;47(10):737-9. Chinese. PMID: 19615205 [PubMed - in process]Related articles

[The surgical separation of pygopagus conjoined twins]

Sun TS, Li F, Zhang ZC, Zhou Z, Wei Q, Li SG, Guan K.

Zhonghua Wai Ke Za Zhi. 2009 Apr 1;47(7):537-40. Chinese. PMID: 19595215 [PubMed - in process]Related articles

[Value of imaging in the preoperative diagnosis of pygopagus conjoined twins]

Zhang ZC, Sun TS, Li F, Guan K, Li SG, Shi SS, Xu ST.

Zhonghua Er Ke Za Zhi. 2009 May;47(5):362-5. Chinese. PMID: 19573408 [PubMed - in process]Related articles

WITHDRAWN: Cancer stem cells sustaining the growth of mouse melanoma are not rare.

Zhong Y, Guan K, Zhou C, Ma W, Wang D, Zhang Y, Zhang S.

Cancer Lett. 2009 May 21. [Epub ahead of print]PMID: 19464102 [PubMed - as supplied by publisher]Related articles

Rheb controls misfolded protein metabolism by inhibiting aggresome formation and autophagy.

Zhou X, Ikenoue T, Chen X, Li L, Inoki K, Guan KL.

Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):8923-8. Epub 2009 May 20.PMID: 19458266 [PubMed - indexed for MEDLINE]Related articles

Inhibition of osteoblastic bone formation by nuclear factor-kappaB.

Chang J, Wang Z, Tang E, Fan Z, McCauley L, Franceschi R, Guan K, Krebsbach PH, Wang CY.

Nat Med. 2009 Jun;15(6):682-9.PMID: 19448637 [PubMed - indexed for MEDLINE]Related articles

The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential.

Mori H, Inoki K, Masutani K, Wakabayashi Y, Komai K, Nakagawa R, Guan KL, Yoshimura A.

Biochem Biophys Res Commun. 2009 Jul 10;384(4):471-5. Epub 2009 May 5.PMID: 19422788 [PubMed - indexed for MEDLINE]Related articles

Generation of functional neurons and glia from multipotent adult mouse germ-line stem cells.

Streckfuss-Bömeke K, Vlasov A, Hülsmann S, Yin D, Nayernia K, Engel W, Hasenfuss G, Guan K.

Stem Cell Res. 2009 Mar;2(2):139-54. Epub 2008 Oct 7.PMID: 19383419 [PubMed - indexed for MEDLINE]Related articles

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha.

Zhao S, Lin Y, Xu W, Jiang W, Zha Z, Wang P, Yu W, Li Z, Gong L, Peng Y, Ding J, Lei Q, Guan KL, Xiong Y.

Science. 2009 Apr 10;324(5924):261-5.PMID: 19359588 [PubMed - indexed for MEDLINE]Related articles

Critical role for hypothalamic mTOR activity in energy balance.

Mori H, Inoki K, Münzberg H, Opland D, Faouzi M, Villanueva EC, Ikenoue T, Kwiatkowski D, MacDougald OA, Myers MG Jr, Guan KL.

Cell Metab. 2009 Apr;9(4):362-74.PMID: 19356717 [PubMed - indexed for MEDLINE]Related articles

Role of TNF-alpha, sTNF-R55 and sTNF-R75 in Inflammation of Acute Exacerbations of Chronic Obstructive Pulmonary Disease.

Zeng M, Wen Y, Liu LY, Wang H, Guan KP, Huang X.

Respiration. 2009 Mar 31;78(4):399-403. [Epub ahead of print]PMID: 19339767 [PubMed - as supplied by publisher]Related articles

TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.

Zhang H, Liu CY, Zha ZY, Zhao B, Yao J, Zhao S, Xiong Y, Lei QY, Guan KL.

J Biol Chem. 2009 May 15;284(20):13355-62. Epub 2009 Mar 26.PMID: 19324877 [PubMed - indexed for MEDLINE]Related articles

Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.

Yu W, Lin Y, Yao J, Huang W, Lei Q, Xiong Y, Zhao S, Guan KL.

J Biol Chem. 2009 May 15;284(20):13669-75. Epub 2009 Mar 23.PMID: 19318352 [PubMed - indexed for MEDLINE]Related articles

Tuberous sclerosis complex, implication from a rare genetic disease to common cancer treatment.

Inoki K, Guan KL.

Hum Mol Genet. 2009 Apr 15;18(R1):R94-100. Review.PMID: 19297407 [PubMed - indexed for MEDLINE]Related articles

Harness the power: new insights into the inhibition of YAP/Yorkie.

Zhao B, Lei QY, Guan KL.

Dev Cell. 2009 Mar;16(3):321-2.PMID: 19289076 [PubMed - indexed for MEDLINE]Related articles

RAG GTPases in nutrient-mediated TOR signaling pathway.

Kim E, Guan KL.

Cell Cycle. 2009 Apr 1;8(7):1014-8. Epub 2009 Apr 9.PMID: 19270521 [PubMed - indexed for MEDLINE]Related articles

Defective development of sensory neurons innervating the levator ani muscle in fetal rats with anorectal malformation.

Guan K, Li H, Fan Y, Wang W, Yuan Z.

Birth Defects Res A Clin Mol Teratol. 2009 Jul;85(7):583-7.PMID: 19248176 [PubMed - indexed for MEDLINE]Related articles

AMP-activated protein kinase and cancer.

Wang W, Guan KL.

Acta Physiol (Oxf). 2009 May;196(1):55-63. Epub 2009 Feb 25.PMID: 19243571 [PubMed - in process]Related articles

DSCAM functions as a netrin receptor in commissural axon pathfinding.

Liu G, Li W, Wang L, Kar A, Guan KL, Rao Y, Wu JY.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2951-6. Epub 2009 Feb 5.PMID: 19196994 [PubMed - indexed for MEDLINE]Related articlesFree article

Isolation and cultivation of stem cells from adult mouse testes.

Guan K, Wolf F, Becker A, Engel W, Nayernia K, Hasenfuss G.

Nat Protoc. 2009;4(2):143-54.PMID: 19180086 [PubMed - indexed for MEDLINE]Related articles

Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein.

Zhao B, Kim J, Ye X, Lai ZC, Guan KL.

Cancer Res. 2009 Feb 1;69(3):1089-98. Epub 2009 Jan 13.PMID: 19141641 [PubMed - indexed for MEDLINE]Related articles

Embryonic stem cell differentiation models: cardiogenesis, myogenesis, neurogenesis, epithelial and vascular smooth muscle cell differentiation in vitro.

Guan K, Rohwedel J, Wobus AM.

Cytotechnology. 1999 Jul;30(1-3):211-26.PMID: 19003371 [PubMed - in process]Related articles

The Hippo-YAP pathway: new connections between regulation of organ size and cancer.

Zhao B, Lei QY, Guan KL.

Curr Opin Cell Biol. 2008 Dec;20(6):638-46. Epub 2008 Nov 18. Review.PMID: 18955139 [PubMed - indexed for MEDLINE]Related articles

TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species.

Chen C, Liu Y, Liu R, Ikenoue T, Guan KL, Liu Y, Zheng P.

J Exp Med. 2008 Sep 29;205(10):2397-408. Epub 2008 Sep 22.PMID: 18809716 [PubMed - indexed for MEDLINE]Related articlesFree article

PTEN acetylation modulates its interaction with PDZ domain.

Ikenoue T, Inoki K, Zhao B, Guan KL.

Cancer Res. 2008 Sep 1;68(17):6908-12.PMID: 18757404 [PubMed - indexed for MEDLINE]Related articlesFree article

AMP-activated protein kinase contributes to UV- and H2O2-induced apoptosis in human skin keratinocytes.

Cao C, Lu S, Kivlin R, Wallin B, Card E, Bagdasarian A, Tamakloe T, Chu WM, Guan KL, Wan Y.

J Biol Chem. 2008 Oct 24;283(43):28897-908. Epub 2008 Aug 20.PMID: 18715874 [PubMed - indexed for MEDLINE]Related articlesFree article

Arbuscular mycorrhizal fungi may serve as another nutrient strategy for some hemiparasitic species of Pedicularis (Orobanchaceae).

Li AR, Guan KY.

Mycorrhiza. 2008 Oct;18(8):429-36. Epub 2008 Aug 15.PMID: 18704514 [PubMed - indexed for MEDLINE]Related articles

Multipotent adult germline stem cells and embryonic stem cells have similar microRNA profiles.

Zovoilis A, Nolte J, Drusenheimer N, Zechner U, Hada H, Guan K, Hasenfuss G, Nayernia K, Engel W.

Mol Hum Reprod. 2008 Sep;14(9):521-9. Epub 2008 Aug 12.PMID: 18697907 [PubMed - indexed for MEDLINE]Related articlesFree article

A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression.

Buller CL, Loberg RD, Fan MH, Zhu Q, Park JL, Vesely E, Inoki K, Guan KL, Brosius FC 3rd.

Am J Physiol Cell Physiol. 2008 Sep;295(3):C836-43. Epub 2008 Jul 23.PMID: 18650261 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of TORC1 by Rag GTPases in nutrient response.

Kim E, Goraksha-Hicks P, Li L, Neufeld TP, Guan KL.

Nat Cell Biol. 2008 Aug;10(8):935-45. Epub 2008 Jul 6.PMID: 18604198 [PubMed - indexed for MEDLINE]Related articlesFree article

TEAD mediates YAP-dependent gene induction and growth control.

Zhao B, Ye X, Yu J, Li L, Li W, Li S, Yu J, Lin JD, Wang CY, Chinnaiyan AM, Lai ZC, Guan KL.

Genes Dev. 2008 Jul 15;22(14):1962-71. Epub 2008 Jun 25.PMID: 18579750 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling.

Ikenoue T, Inoki K, Yang Q, Zhou X, Guan KL.

EMBO J. 2008 Jul 23;27(14):1919-31. Epub 2008 Jun 19. Erratum in: EMBO J. 2008 Aug 20;27(16):2270. PMID: 18566587 [PubMed - indexed for MEDLINE]Related articlesFree article

Potency of germ cells and its relevance for regenerative medicine.

Mardanpour P, Guan K, Nolte J, Lee JH, Hasenfuss G, Engel W, Nayernia K.

J Anat. 2008 Jul;213(1):26-9. Epub 2008 Jun 28. Review.PMID: 18565110 [PubMed - indexed for MEDLINE]Related articles

Substrate selectivity APPLies to Akt.

Zhao S, Guan KL.

Cell. 2008 May 2;133(3):399-400.PMID: 18455980 [PubMed - indexed for MEDLINE]Related articles

[Cloning of PD-1 gene and its prokaryotic expression in Escherichia coli]

Chen SY, Guan KP, Guo MZ, Yi Y, Jia ZY, Yu T, Guo Y, Bi SL.

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2008 Feb;22(1):33-5. Chinese. PMID: 18414695 [PubMed - indexed for MEDLINE]Related articles

TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway.

Lei QY, Zhang H, Zhao B, Zha ZY, Bai F, Pei XH, Zhao S, Xiong Y, Guan KL.

Mol Cell Biol. 2008 Apr;28(7):2426-36. Epub 2008 Jan 28.PMID: 18227151 [PubMed - indexed for MEDLINE]Related articlesFree article

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.

Zhao B, Wei X, Li W, Udan RS, Yang Q, Kim J, Xie J, Ikenoue T, Yu J, Li L, Zheng P, Ye K, Chinnaiyan A, Halder G, Lai ZC, Guan KL.

Genes Dev. 2007 Nov 1;21(21):2747-61.PMID: 17974916 [PubMed - indexed for MEDLINE]Related articlesFree article

Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53.

Lee CH, Inoki K, Karbowniczek M, Petroulakis E, Sonenberg N, Henske EP, Guan KL.

EMBO J. 2007 Nov 28;26(23):4812-23. Epub 2007 Oct 25.PMID: 17962806 [PubMed - indexed for MEDLINE]Related articlesFree article

Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb.

Li Y, Wang Y, Kim E, Beemiller P, Wang CY, Swanson J, You M, Guan KL.

J Biol Chem. 2007 Dec 7;282(49):35803-13. Epub 2007 Oct 10.PMID: 17928295 [PubMed - indexed for MEDLINE]Related articlesFree article

Do stem cells in the heart truly differentiate into cardiomyocytes?

Guan K, Hasenfuss G.

J Mol Cell Cardiol. 2007 Oct;43(4):377-87. Epub 2007 Jul 31. Review.PMID: 17716688 [PubMed - indexed for MEDLINE]Related articles

Expanding mTOR signaling.

Yang Q, Guan KL.

Cell Res. 2007 Aug;17(8):666-81. Review.PMID: 17680028 [PubMed - indexed for MEDLINE]Related articlesFree article

Generation of functional cardiomyocytes from adult mouse spermatogonial stem cells.

Guan K, Wagner S, Unsöld B, Maier LS, Kaiser D, Hemmerlein B, Nayernia K, Engel W, Hasenfuss G.

Circ Res. 2007 Jun 8;100(11):1615-25. Epub 2007 May 3.PMID: 17478732 [PubMed - indexed for MEDLINE]Related articlesFree article

[Quantitative analysis of sensory neurons innervating the muscle levator ani in rats with anorectal malformation]

Guan KP, Yuan ZW, Wang WL, Gao F, Su PJ.

Zhonghua Yi Xue Za Zhi. 2007 Jan 9;87(2):131-3. Chinese. PMID: 17418024 [PubMed - indexed for MEDLINE]Related articles

Surgical macular decompression for macular edema in retinal vein occlusion.

Mandelcorn MS, Mandelcorn E, Guan K, Adatia FA.

Can J Ophthalmol. 2007 Feb;42(1):116-22.PMID: 17361252 [PubMed - indexed for MEDLINE]Related articlesFree article