PubMed

Progression to microalbuminuria in type 1 diabetes: development and validation of a prediction rule.

Vergouwe Y, Soedamah-Muthu SS, Zgibor J, Chaturvedi N, Forsblom C, Snell-Bergeon JK, Maahs DM, Groop PH, Rewers M, Orchard TJ, Fuller JH, Moons KG.

Diabetologia. 2009 Nov 4. [Epub ahead of print]PMID: 19908023 [PubMed - as supplied by publisher]Related articles

Effect of hot flushes on vascular function: a randomized controlled trial.

Tuomikoski P, Ebert P, Groop PH, Haapalahti P, Hautamäki H, Rönnback M, Ylikorkala O, Mikkola TS.

Obstet Gynecol. 2009 Oct;114(4):777-85.PMID: 19888035 [PubMed - in process]Related articles

Effects of Long-Term Fenofibrate Treatment on Markers of Renal Function in Type 2 Diabetes: FIELD Helsinki Substudy.

Forsblom C, Hiukka A, Leinonen ES, Sundvall J, Groop PH, Taskinen MR.

Diabetes Care. 2009 Oct 21. [Epub ahead of print]PMID: 19846798 [PubMed - as supplied by publisher]Related articles

AGE AT ONSET OF TYPE 1 DIABETES IN PARENTS AND RECURRENCE RISK IN OFFSPRING.

Harjutsalo V, Lammi N, Karvonen M, Groop PH.

Diabetes. 2009 Oct 15. [Epub ahead of print]PMID: 19833881 [PubMed - as supplied by publisher]Related articles

Lipid abnormalities predict progression of renal disease in patients with type 1 diabetes.

Tolonen N, Forsblom C, Thorn L, Wadén J, Rosengård-Bärlund M, Saraheimo M, Feodoroff M, Mäkinen VP, Gordin D, Taskinen MR, Groop PH; FinnDiane Study Group.

Diabetologia. 2009 Oct 10. [Epub ahead of print]PMID: 19816673 [PubMed - as supplied by publisher]Related articles

Network of vascular diseases, death and biochemical characteristics in a set of 4,197 patients with type 1 diabetes (The FinnDiane Study).

Mäkinen VP, Forsblom C, Thorn LM, Wadén J, Kaski K, Ala-Korpela M, Groop PH.

Cardiovasc Diabetol. 2009 Oct 6;8:54.PMID: 19804653 [PubMed - in process]Related articlesFree article

A1C variability predicts incident cardiovascular events, microalbuminuria, and overt diabetic nephropathy in patients with type 1 diabetes.

Wadén J, Forsblom C, Thorn LM, Gordin D, Saraheimo M, Groop PH; Finnish Diabetic Nephropathy Study Group.

Diabetes. 2009 Nov;58(11):2649-55. Epub 2009 Aug 3.PMID: 19651819 [PubMed - in process]Related articles

Functional annotations of diabetes nephropathy susceptibility loci through analysis of genome-wide renal gene expression in rat models of diabetes mellitus.

Hu Y, Kaisaki PJ, Argoud K, Wilder SP, Wallace KJ, Woon PY, Blancher C, Tarnow L, Groop PH, Hadjadj S, Marre M, Parving HH, Farrall M, Cox RD, Lathrop M, Vionnet N, Bihoreau MT, Gauguier D.

BMC Med Genomics. 2009 Jul 9;2:41.PMID: 19586551 [PubMed - in process]Related articlesFree article

Telomere length and progression of diabetic nephropathy in patients with type 1 diabetes.

Fyhrquist F, Tiitu A, Saijonmaa O, Forsblom C, Groop PH; on behalf of the FinnDiane Study Group.

J Intern Med. 2009 Jun 4. [Epub ahead of print]PMID: 19563389 [PubMed - as supplied by publisher]Related articles

Serum lipopolysaccharide activity is associated with the progression of kidney disease in finnish patients with type 1 diabetes.

Nymark M, Pussinen PJ, Tuomainen AM, Forsblom C, Groop PH, Lehto M; FinnDiane Study Group.

Diabetes Care. 2009 Sep;32(9):1689-93. Epub 2009 Jun 5.PMID: 19502539 [PubMed - indexed for MEDLINE]Related articles

Adult stature and diabetes complications in patients with type 1 diabetes: the FinnDiane Study and the diabetes control and complications trial.

Wadén J, Forsblom C, Thorn LM, Saraheimo M, Rosengård-Bärlund M, Heikkilä O, Hietala K, Ong K, Wareham N, Groop PH; FinnDiane Study Group.

Diabetes. 2009 Aug;58(8):1914-20. Epub 2009 Jun 2.PMID: 19491208 [PubMed - indexed for MEDLINE]Related articlesFree article

Estimation of VLDL, IDL, LDL, HDL(2), apoA-I, and apoB from the Friedewald inputs-apoB and IDL, but not LDL, are associated with mortality in type 1 diabetes.

Niemi J, Makinen VP, Heikkonen J, Tenkanen L, Hiltunen Y, Hannuksela ML, Jauhiainen M, Forsblom C, Taskinen MR, Kesaniemi YA, Savolainen MJ, Kaski K, Groop PH, Kovanen PT, Ala-Korpela M.

Ann Med. 2009 May 1:1-11. [Epub ahead of print]PMID: 19412820 [PubMed - as supplied by publisher]Related articles

The presence and severity of chronic kidney disease predicts all-cause mortality in type 1 diabetes.

Groop PH, Thomas MC, Moran JL, Wadèn J, Thorn LM, Mäkinen VP, Rosengård-Bärlund M, Saraheimo M, Hietala K, Heikkilä O, Forsblom C; FinnDiane Study Group.

Diabetes. 2009 Jul;58(7):1651-8. Epub 2009 Apr 28.PMID: 19401416 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated MBL concentrations are not an indication of association between the MBL2 gene and type 1 diabetes or diabetic nephropathy.

Kaunisto MA, Sjölind L, Sallinen R, Pettersson-Fernholm K, Saraheimo M, Fröjdö S, Forsblom C, Fagerudd J, Hansen TK, Flyvbjerg A, Wessman M, Groop PH; FinnDiane Study Group.

Diabetes. 2009 Jul;58(7):1710-4. Epub 2009 Apr 14.PMID: 19366862 [PubMed - indexed for MEDLINE]Related articlesFree article

Early autonomic dysfunction in type 1 diabetes: a reversible disorder?

Rosengård-Bärlund M, Bernardi L, Fagerudd J, Mäntysaari M, Af Björkesten CG, Lindholm H, Forsblom C, Wadén J, Groop PH; FinnDiane Study Group.

Diabetologia. 2009 Jun;52(6):1164-72. Epub 2009 Apr 2.PMID: 19340407 [PubMed - indexed for MEDLINE]Related articles

Evidence for a role of hot flushes in vascular function in recently postmenopausal women.

Tuomikoski P, Ebert P, Groop PH, Haapalahti P, Hautamäki H, Rönnback M, Ylikorkala O, Mikkola TS.

Obstet Gynecol. 2009 Apr;113(4):902-8.PMID: 19305337 [PubMed - indexed for MEDLINE]Related articles

Investigation of DNA polymorphisms in SMAD genes for genetic predisposition to diabetic nephropathy in patients with type 1 diabetes mellitus.

McKnight AJ, Woodman AM, Parkkonen M, Patterson CC, Savage DA, Forsblom C, Pettigrew KA, Sadlier D, Groop PH, Maxwell AP; Warren 3/UK GoKinD Study Group.

Diabetologia. 2009 May;52(5):844-9. Epub 2009 Feb 27.PMID: 19247629 [PubMed - indexed for MEDLINE]Related articles

Metabolic syndrome as a risk factor for cardiovascular disease, mortality, and progression of diabetic nephropathy in type 1 diabetes.

Thorn LM, Forsblom C, Wadén J, Saraheimo M, Tolonen N, Hietala K, Groop PH; Finnish Diabetic Nephropathy (FinnDiane) Study Group.

Diabetes Care. 2009 May;32(5):950-2. Epub 2009 Feb 5.PMID: 19196885 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperglycaemia is associated with changes in the regional concentrations of glucose and myo-inositol within the brain.

Heikkilä O, Lundbom N, Timonen M, Groop PH, Heikkinen S, Mäkimattila S.

Diabetologia. 2009 Mar;52(3):534-40. Epub 2008 Dec 19.PMID: 19096823 [PubMed - indexed for MEDLINE]Related articles

Association of genetic variants at 3q22 with nephropathy in patients with type 1 diabetes mellitus.

He B, Osterholm AM, Hoverfält A, Forsblom C, Hjörleifsdóttir EE, Nilsson AS, Parkkonen M, Pitkäniemi J, Hreidarsson A, Sarti C, McKnight AJ, Maxwell AP, Tuomilehto J, Groop PH, Tryggvason K.

Am J Hum Genet. 2009 Jan;84(1):5-13. Epub 2008 Dec 11.PMID: 19084216 [PubMed - indexed for MEDLINE]Related articlesFree article

The MIF receptor CD74 in diabetic podocyte injury.

Sanchez-Niño MD, Sanz AB, Ihalmo P, Lassila M, Holthofer H, Mezzano S, Aros C, Groop PH, Saleem MA, Mathieson PW, Langham R, Kretzler M, Nair V, Lemley KV, Nelson RG, Mervaala E, Mattinzoli D, Rastaldi MP, Ruiz-Ortega M, Martin-Ventura JL, Egido J, Ortiz A.

J Am Soc Nephrol. 2009 Feb;20(2):353-62. Epub 2008 Oct 8.PMID: 18842989 [PubMed - indexed for MEDLINE]Related articles

Effect of parental type 2 diabetes on offspring with type 1 diabetes.

Thorn LM, Forsblom C, Wadén J, Söderlund J, Rosengård-Bärlund M, Saraheimo M, Heikkilä O, Hietala K, Pettersson-Fernholm K, Ilonen J, Groop PH; FinnDiane Study Group.

Diabetes Care. 2009 Jan;32(1):63-8. Epub 2008 Oct 3.PMID: 18835950 [PubMed - in process]Related articlesFree article

A multi-metabolite analysis of serum by 1H NMR spectroscopy: early systemic signs of Alzheimer's disease.

Tukiainen T, Tynkkynen T, Mäkinen VP, Jylänki P, Kangas A, Hokkanen J, Vehtari A, Gröhn O, Hallikainen M, Soininen H, Kivipelto M, Groop PH, Kaski K, Laatikainen R, Soininen P, Pirttilä T, Ala-Korpela M.

Biochem Biophys Res Commun. 2008 Oct 24;375(3):356-61. Epub 2008 Aug 26.PMID: 18700135 [PubMed - indexed for MEDLINE]Related articles

Risk for metabolic syndrome predisposes to alterations in the thalamic metabolism.

Heikkilä O, Lundbom N, Timonen M, Groop PH, Heikkinen S, Mäkimattila S.

Metab Brain Dis. 2008 Sep;23(3):315-24. Epub 2008 Jul 22.PMID: 18648915 [PubMed - indexed for MEDLINE]Related articles

G/T substitution in intron 1 of the UNC13B gene is associated with increased risk of nephropathy in patients with type 1 diabetes.

Trégouet DA, Groop PH, McGinn S, Forsblom C, Hadjadj S, Marre M, Parving HH, Tarnow L, Telgmann R, Godefroy T, Nicaud V, Rousseau R, Parkkonen M, Hoverfält A, Gut I, Heath S, Matsuda F, Cox R, Kazeem G, Farrall M, Gauguier D, Brand-Herrmann SM, Cambien F, Lathrop M, Vionnet N; EURAGEDIC Consortium.

Diabetes. 2008 Oct;57(10):2843-50. Epub 2008 Jul 15.PMID: 18633107 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute hyperglycaemia induces an inflammatory response in young patients with type 1 diabetes.

Gordin D, Forsblom C, Rönnback M, Parkkonen M, Wadén J, Hietala K, Groop PH.

Ann Med. 2008;40(8):627-33.PMID: 18608123 [PubMed - indexed for MEDLINE]Related articles

A relationship between insulin sensitivity and vasodilation in women with a history of preeclamptic pregnancy.

Lampinen KH, Rönnback M, Groop PH, Kaaja RJ.

Hypertension. 2008 Aug;52(2):394-401. Epub 2008 Jun 23.PMID: 18574072 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic phenotypes, vascular complications, and premature deaths in a population of 4,197 patients with type 1 diabetes.

Mäkinen VP, Forsblom C, Thorn LM, Wadén J, Gordin D, Heikkilä O, Hietala K, Kyllönen L, Kytö J, Rosengård-Bärlund M, Saraheimo M, Tolonen N, Parkkonen M, Kaski K, Ala-Korpela M, Groop PH; FinnDiane Study Group.

Diabetes. 2008 Sep;57(9):2480-7. Epub 2008 Jun 10.PMID: 18544706 [PubMed - indexed for MEDLINE]Related articlesFree article

Heritability of proliferative diabetic retinopathy.

Hietala K, Forsblom C, Summanen P, Groop PH; FinnDiane Study Group.

Diabetes. 2008 Aug;57(8):2176-80. Epub 2008 Apr 28.PMID: 18443200 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum adiponectin and progression of diabetic nephropathy in patients with type 1 diabetes.

Saraheimo M, Forsblom C, Thorn L, Wadén J, Rosengård-Bärlund M, Heikkilä O, Hietala K, Gordin D, Frystyk J, Flyvbjerg A, Groop PH; FinnDiane Study Group.

Diabetes Care. 2008 Jun;31(6):1165-9. Epub 2008 Mar 17.PMID: 18346990 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose variability, blood pressure and arterial stiffness in type 1 diabetes.

Gordin D, Rönnback M, Forsblom C, Mäkinen V, Saraheimo M, Groop PH.

Diabetes Res Clin Pract. 2008 Jun;80(3):e4-7. Epub 2008 Mar 5.PMID: 18325620 [PubMed - indexed for MEDLINE]Related articles

1H NMR metabonomics approach to the disease continuum of diabetic complications and premature death.

Mäkinen VP, Soininen P, Forsblom C, Parkkonen M, Ingman P, Kaski K, Groop PH; FinnDiane Study Group, Ala-Korpela M.

Mol Syst Biol. 2008;4:167. Epub 2008 Feb 12.PMID: 18277383 [PubMed - indexed for MEDLINE]Related articlesFree article

The R-Ras interaction partner ORP3 regulates cell adhesion.

Lehto M, Mäyränpää MI, Pellinen T, Ihalmo P, Lehtonen S, Kovanen PT, Groop PH, Ivaska J, Olkkonen VM.

J Cell Sci. 2008 Mar 1;121(Pt 5):695-705. Epub 2008 Feb 12.PMID: 18270267 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute hyperglycaemia disturbs cardiac repolarization in Type 1 diabetes.

Gordin D, Forsblom C, Rönnback M, Groop PH.

Diabet Med. 2008 Jan;25(1):101-5.PMID: 18199138 [PubMed - indexed for MEDLINE]Related articles

Screening for chronic kidney disease in patients with diabetes: are we missing the point?

Thomas MC, Viberti G, Groop PH.

Nat Clin Pract Nephrol. 2008 Jan;4(1):2-3. Epub 2007 Nov 27. No abstract available. PMID: 18043592 [PubMed - indexed for MEDLINE]Related articles

Increased levels of alpha-defensin (-1, -2 and -3) in type 1 diabetic patients with nephropathy.

Saraheimo M, Forsblom C, Pettersson-Fernholm K, Flyvbjerg A, Groop PH, Frystyk J; FinnDiane Study Group.

Nephrol Dial Transplant. 2008 Mar;23(3):914-8. Epub 2007 Nov 14.PMID: 18003664 [PubMed - indexed for MEDLINE]Related articles

Relationship between lipid profiles and kidney function in patients with type 1 diabetes.

Tolonen N, Forsblom C, Thorn L, Wadén J, Rosengård-Bärlund M, Saraheimo M, Heikkilä O, Pettersson-Fernholm K, Taskinen MR, Groop PH; FinnDiane Study Group.

Diabetologia. 2008 Jan;51(1):12-20. Epub 2007 Nov 10.PMID: 17994214 [PubMed - indexed for MEDLINE]Related articles

Association analysis of podocyte slit diaphragm genes as candidates for diabetic nephropathy.

Ihalmo P, Wessman M, Kaunisto MA, Kilpikari R, Parkkonen M, Forsblom C, Holthöfer H, Groop PH; FinnDiane Study Group.

Diabetologia. 2008 Jan;51(1):86-90. Epub 2007 Oct 30.PMID: 17968527 [PubMed - indexed for MEDLINE]Related articles

Equol production capability is associated with favorable vascular function in postmenopausal women using tibolone; no effect with soy supplementation.

Törmälä R, Appt S, Clarkson TB, Groop PH, Rönnback M, Ylikorkala O, Mikkola TS.

Atherosclerosis. 2008 May;198(1):174-8. Epub 2007 Oct 24.PMID: 17961576 [PubMed - indexed for MEDLINE]Related articles

Physical activity and diabetes complications in patients with type 1 diabetes: the Finnish Diabetic Nephropathy (FinnDiane) Study.

Wadén J, Forsblom C, Thorn LM, Saraheimo M, Rosengård-Bärlund M, Heikkilä O, Lakka TA, Tikkanen H, Groop PH; FinnDiane Study Group.

Diabetes Care. 2008 Feb;31(2):230-2. Epub 2007 Oct 24. No abstract available. PMID: 17959867 [PubMed - indexed for MEDLINE]Related articlesFree article

European rational approach for the genetics of diabetic complications--EURAGEDIC: patient populations and strategy.

Tarnow L, Groop PH, Hadjadj S, Kazeem G, Cambien F, Marre M, Forsblom C, Parving HH, Trégouët D, Thévard A, Farrall M, Gut I, Gauguier D, Cox R, Matsuda F, Lathrop M, Vionnet N; EURAGEDIC Consortium.

Nephrol Dial Transplant. 2008 Jan;23(1):161-8. Epub 2007 Aug 17.PMID: 17704113 [PubMed - indexed for MEDLINE]Related articles

HDL composition predicts new-onset cardiovascular disease in patients with type 1 diabetes.

Groop PH, Thomas MC, Rosengård-Bärlund M, Mills V, Rönnback M, Thomas S, Forsblom C, Taskinen MR, Viberti G.

Diabetes Care. 2007 Oct;30(10):2706-7. Epub 2007 Jul 9. No abstract available. PMID: 17620444 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute hyperglycaemia rapidly increases arterial stiffness in young patients with type 1 diabetes.

Gordin D, Rönnback M, Forsblom C, Heikkilä O, Saraheimo M, Groop PH.

Diabetologia. 2007 Sep;50(9):1808-14. Epub 2007 Jul 5.PMID: 17611734 [PubMed - indexed for MEDLINE]Related articles

Association between angiotensin-converting enzyme gene polymorphisms and diabetic nephropathy: case-control, haplotype, and family-based study in three European populations.

Hadjadj S, Tarnow L, Forsblom C, Kazeem G, Marre M, Groop PH, Parving HH, Cambien F, Tregouet DA, Gut IG, Théva A, Gauguier D, Farrall M, Cox R, Matsuda F, Lathrop M, Hager-Vionnet N; EURAGEDIC (European Rational Approach for Genetics of Diabetic Complications) Study Group.

J Am Soc Nephrol. 2007 Apr;18(4):1284-91. Epub 2007 Mar 21.PMID: 17376814 [PubMed - indexed for MEDLINE]Related articlesFree article

Leisure-time physical activity is associated with the metabolic syndrome in type 1 diabetes: effect of the PPARgamma Pro12Ala polymorphism: the FinnDiane Study.

Wadén J, Thorn LM, Forsblom C, Lakka T, Saraheimo M, Rosengård-Bärlund M, Heikkilä O, Wessman M, Turunen JA, Parkkonen M, Tikkanen H, Groop PH; FinnDiane Study Group.

Diabetes Care. 2007 Jun;30(6):1618-20. Epub 2007 Mar 10. No abstract available. PMID: 17351273 [PubMed - indexed for MEDLINE]Related articlesFree article

Clustering of risk factors in parents of patients with type 1 diabetes and nephropathy.

Thorn LM, Forsblom C, Fagerudd J, Pettersson-Fernholm K, Kilpikari R, Groop PH; FinnDiane Study Group.

Diabetes Care. 2007 May;30(5):1162-7. Epub 2007 Mar 2.PMID: 17337502 [PubMed - indexed for MEDLINE]Related articlesFree article

Pre-eclampsia but not pregnancy-induced hypertension is a risk factor for diabetic nephropathy in type 1 diabetic women.

Gordin D, Hiilesmaa V, Fagerudd J, Rönnback M, Forsblom C, Kaaja R, Teramo K, Groop PH; FinnDiane Study Group.

Diabetologia. 2007 Mar;50(3):516-22. Epub 2007 Jan 10.PMID: 17216281 [PubMed - indexed for MEDLINE]Related articles

A functional polymorphism in the manganese superoxide dismutase gene and diabetic nephropathy.

Möllsten A, Marklund SL, Wessman M, Svensson M, Forsblom C, Parkkonen M, Brismar K, Groop PH, Dahlquist G.

Diabetes. 2007 Jan;56(1):265-9.PMID: 17192491 [PubMed - indexed for MEDLINE]Related articlesFree article

Diagnosing diabetic nephropathy by 1H NMR metabonomics of serum.

Mäkinen VP, Soininen P, Forsblom C, Parkkonen M, Ingman P, Kaski K, Groop PH, Ala-Korpela M; FinnDiane Study Group.

MAGMA. 2006 Dec;19(6):281-96. Epub 2006 Dec 15.PMID: 17171386 [PubMed - indexed for MEDLINE]Related articles

Glu298Asp and NOS4ab polymorphisms in diabetic nephropathy.

Möllsten A, Wessman M, Svensson M, Forsblom C, Parkkonen M, Brismar K, Groop PH, Dahlquist G.

Ann Med. 2006;38(7):522-8.PMID: 17101543 [PubMed - indexed for MEDLINE]Related articles