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Results: 1 to 50 of 446

1.

Stressful life events and the metabolic syndrome: The PPP-Botnia Study.

Pyykkönen AJ, Räikkönen K, Tuomi T, Eriksson JG, Groop L, Isomaa B.

Diabetes Care. 2009 Oct 30. [Epub ahead of print]PMID: 19880581 [PubMed - as supplied by publisher]Related articles

2.

An empirical index of insulin sensitivity from short IVGTT: validation against the minimal model and glucose clamp indices in patients with different clinical characteristics.

Tura A, Sbrignadello S, Succurro E, Groop L, Sesti G, Pacini G.

Diabetologia. 2009 Oct 30. [Epub ahead of print]PMID: 19876614 [PubMed - as supplied by publisher]Related articles

3.

GADA positivity predicts non-insulin dependent diabetes in an adult population.

Lundgren VM, Isomaa B, Lyssenko V, Laurila E, Korhonen P, Groop LC, Tuomi T; for the Botnia Study Group.

Diabetes. 2009 Oct 28. [Epub ahead of print]PMID: 19864397 [PubMed - as supplied by publisher]Related articles

4.

Genetic association analysis of LARS2 with type 2 diabetes.

Reiling E, Jafar-Mohammadi B, van 't Riet E, Weedon MN, van Vliet-Ostaptchouk JV, Hansen T, Saxena R, van Haeften TW, Arp PA, Das S, Nijpels G, Groenewoud MJ, van Hove EC, Uitterlinden AG, Smit JW, Morris AD, Doney AS, Palmer CN, Guiducci C, Hattersley AT, Frayling TM, Pedersen O, Slagboom PE, Altshuler DM, Groop L, Romijn JA, Maassen JA, Hofker MH, Dekker JM, McCarthy MI, 't Hart LM.

Diabetologia. 2009 Oct 22. [Epub ahead of print]PMID: 19847392 [PubMed - as supplied by publisher]Related articles

5.

Genetic basis of beta-cell dysfunction in man.

Groop L, Lyssenko V.

Diabetes Obes Metab. 2009 Nov;11 Suppl 4:149-58.PMID: 19817797 [PubMed - in process]Related articles

6.

Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion.

Malmgren S, Nicholls DG, Taneera J, Bacos K, Koeck T, Tamaddon A, Wibom R, Groop L, Ling C, Mulder H, Sharoyko VV.

J Biol Chem. 2009 Nov 20;284(47):32395-404. Epub 2009 Sep 21.PMID: 19797055 [PubMed - in process]Related articles

7.

Erratum to: Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes.

Pulizzi N, Lyssenko V, Jonsson A, Osmond C, Laakso M, Kajantie E, Barker DJ, Groop LC, Eriksson JG.

Diabetologia. 2009 Sep 26. [Epub ahead of print] No abstract available. PMID: 19784616 [PubMed - as supplied by publisher]Related articles

8.

An investigation of serum concentration of apoM as a potential MODY3 marker using a novel ELISA.

Cervin C, Axler O, Holmkvist J, Almgren P, Rantala E, Tuomi T, Groop L, Dahlbäck B, Karlsson E.

J Intern Med. 2009 Jun 22. [Epub ahead of print]PMID: 19754856 [PubMed - as supplied by publisher]Related articles

9.

Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs.

Tönjes A, Koriath M, Schleinitz D, Dietrich K, Böttcher Y, Rayner NW, Almgren P, Enigk B, Richter O, Rohm S, Fischer-Rosinsky A, Pfeiffer A, Hoffmann K, Krohn K, Aust G, Spranger J, Groop L, Blüher M, Kovacs P, Stumvoll M.

Hum Mol Genet. 2009 Dec 1;18(23):4662-8. Epub 2009 Sep 3.PMID: 19729412 [PubMed - in process]Related articlesFree article

10.

Calpain-10 expression is elevated in pancreatic islets from patients with type 2 diabetes.

Ling C, Groop L, Guerra SD, Lupi R.

PLoS One. 2009 Aug 18;4(8):e6558.PMID: 19688040 [PubMed - in process]Related articlesFree article

11.

Underlying genetic models of inheritance in established type 2 diabetes associations.

Salanti G, Southam L, Altshuler D, Ardlie K, Barroso I, Boehnke M, Cornelis MC, Frayling TM, Grallert H, Grarup N, Groop L, Hansen T, Hattersley AT, Hu FB, Hveem K, Illig T, Kuusisto J, Laakso M, Langenberg C, Lyssenko V, McCarthy MI, Morris A, Morris AD, Palmer CN, Payne F, Platou CG, Scott LJ, Voight BF, Wareham NJ, Zeggini E, Ioannidis JP.

Am J Epidemiol. 2009 Sep 1;170(5):537-45. Epub 2009 Jul 14.PMID: 19602701 [PubMed - indexed for MEDLINE]Related articles

12.

Tissue-specific alternative splicing of TCF7L2.

Prokunina-Olsson L, Welch C, Hansson O, Adhikari N, Scott LJ, Usher N, Tong M, Sprau A, Swift A, Bonnycastle LL, Erdos MR, He Z, Saxena R, Harmon B, Kotova O, Hoffman EP, Altshuler D, Groop L, Boehnke M, Collins FS, Hall JL.

Hum Mol Genet. 2009 Oct 15;18(20):3795-804. Epub 2009 Jul 14.PMID: 19602480 [PubMed - in process]Related articlesFree article

13.

Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue.

Grunnet LG, Nilsson E, Ling C, Hansen T, Pedersen O, Groop L, Vaag A, Poulsen P.

Diabetes. 2009 Oct;58(10):2402-8. Epub 2009 Jul 8.PMID: 19587359 [PubMed - indexed for MEDLINE]Related articles

14.

A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.

Jonsson A, Isomaa B, Tuomi T, Taneera J, Salehi A, Nilsson P, Groop L, Lyssenko V.

Diabetes. 2009 Oct;58(10):2409-13. Epub 2009 Jul 7.PMID: 19584308 [PubMed - indexed for MEDLINE]Related articles

16.

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.

Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G, Willer CJ, Herrera BM, Jackson AU, Lim N, Scheet P, Soranzo N, Amin N, Aulchenko YS, Chambers JC, Drong A, Luan J, Lyon HN, Rivadeneira F, Sanna S, Timpson NJ, Zillikens MC, Zhao JH, Almgren P, Bandinelli S, Bennett AJ, Bergman RN, Bonnycastle LL, Bumpstead SJ, Chanock SJ, Cherkas L, Chines P, Coin L, Cooper C, Crawford G, Doering A, Dominiczak A, Doney AS, Ebrahim S, Elliott P, Erdos MR, Estrada K, Ferrucci L, Fischer G, Forouhi NG, Gieger C, Grallert H, Groves CJ, Grundy S, Guiducci C, Hadley D, Hamsten A, Havulinna AS, Hofman A, Holle R, Holloway JW, Illig T, Isomaa B, Jacobs LC, Jameson K, Jousilahti P, Karpe F, Kuusisto J, Laitinen J, Lathrop GM, Lawlor DA, Mangino M, McArdle WL, Meitinger T, Morken MA, Morris AP, Munroe P, Narisu N, Nordström A, Nordström P, Oostra BA, Palmer CN, Payne F, Peden JF, Prokopenko I, Renström F, Ruokonen A, Salomaa V, Sandhu MS, Scott LJ, Scuteri A, Silander K, Song K, Yuan X, Stringham HM, Swift AJ, Tuomi T, Uda M, Vollenweider P, Waeber G, Wallace C, Walters GB, Weedon MN; Wellcome Trust Case Control Consortium, Witteman JC, Zhang C, Zhang W, Caulfield MJ, Collins FS, Davey Smith G, Day IN, Franks PW, Hattersley AT, Hu FB, Jarvelin MR, Kong A, Kooner JS, Laakso M, Lakatta E, Mooser V, Morris AD, Peltonen L, Samani NJ, Spector TD, Strachan DP, Tanaka T, Tuomilehto J, Uitterlinden AG, van Duijn CM, Wareham NJ, Hugh Watkins; Procardis Consortia, Waterworth DM, Boehnke M, Deloukas P, Groop L, Hunter DJ, Thorsteinsdottir U, Schlessinger D, Wichmann HE, Frayling TM, Abecasis GR, Hirschhorn JN, Loos RJ, Stefansson K, Mohlke KL, Barroso I, McCarthy MI; Giant Consortium.

PLoS Genet. 2009 Jun;5(6):e1000508. Epub 2009 Jun 26. Erratum in: PLoS Genet. 2009 Jul;5(7). doi: 10.1371/annotation/b6e8f9f6-2496-4a40-b0e3-e1d1390c1928. PMID: 19557161 [PubMed - indexed for MEDLINE]Related articlesFree article

17.

Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.

Kotronen A, Peltonen M, Hakkarainen A, Sevastianova K, Bergholm R, Johansson LM, Lundbom N, Rissanen A, Ridderstråle M, Groop L, Orho-Melander M, Yki-Järvinen H.

Gastroenterology. 2009 Sep;137(3):865-72. Epub 2009 Jun 12.PMID: 19524579 [PubMed - indexed for MEDLINE]Related articles

18.

Control of ACAT2 liver expression by HNF4{alpha}: lesson from MODY1 patients.

Pramfalk C, Karlsson E, Groop L, Rudel LL, Angelin B, Eriksson M, Parini P.

Arterioscler Thromb Vasc Biol. 2009 Aug;29(8):1235-41. Epub 2009 May 28.PMID: 19478207 [PubMed - indexed for MEDLINE]Related articles

19.

Evaluation of the effects of exercise on insulin sensitivity in Arabian and Swedish women with type 2 diabetes.

Glans F, Eriksson KF, Segerström A, Thorsson O, Wollmer P, Groop L.

Diabetes Res Clin Pract. 2009 Jul;85(1):69-74. Epub 2009 May 17.PMID: 19447515 [PubMed - indexed for MEDLINE]Related articles

20.

Genome-wide association study identifies eight loci associated with blood pressure.

Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH, Heath SC, Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F, Farrall M, Tanaka T, Wallace C, Chambers JC, Khaw KT, Nilsson P, van der Harst P, Polidoro S, Grobbee DE, Onland-Moret NC, Bots ML, Wain LV, Elliott KS, Teumer A, Luan J, Lucas G, Kuusisto J, Burton PR, Hadley D, McArdle WL; Wellcome Trust Case Control Consortium, Brown M, Dominiczak A, Newhouse SJ, Samani NJ, Webster J, Zeggini E, Beckmann JS, Bergmann S, Lim N, Song K, Vollenweider P, Waeber G, Waterworth DM, Yuan X, Groop L, Orho-Melander M, Allione A, Di Gregorio A, Guarrera S, Panico S, Ricceri F, Romanazzi V, Sacerdote C, Vineis P, Barroso I, Sandhu MS, Luben RN, Crawford GJ, Jousilahti P, Perola M, Boehnke M, Bonnycastle LL, Collins FS, Jackson AU, Mohlke KL, Stringham HM, Valle TT, Willer CJ, Bergman RN, Morken MA, Döring A, Gieger C, Illig T, Meitinger T, Org E, Pfeufer A, Wichmann HE, Kathiresan S, Marrugat J, O'Donnell CJ, Schwartz SM, Siscovick DS, Subirana I, Freimer NB, Hartikainen AL, McCarthy MI, O'Reilly PF, Peltonen L, Pouta A, de Jong PE, Snieder H, van Gilst WH, Clarke R, Goel A, Hamsten A, Peden JF, Seedorf U, Syvänen AC, Tognoni G, Lakatta EG, Sanna S, Scheet P, Schlessinger D, Scuteri A, Dörr M, Ernst F, Felix SB, Homuth G, Lorbeer R, Reffelmann T, Rettig R, Völker U, Galan P, Gut IG, Hercberg S, Lathrop GM, Zelenika D, Deloukas P, Soranzo N, Williams FM, Zhai G, Salomaa V, Laakso M, Elosua R, Forouhi NG, Völzke H, Uiterwaal CS, van der Schouw YT, Numans ME, Matullo G, Navis G, Berglund G, Bingham SA, Kooner JS, Connell JM, Bandinelli S, Ferrucci L, Watkins H, Spector TD, Tuomilehto J, Altshuler D, Strachan DP, Laan M, Meneton P, Wareham NJ, Uda M, Jarvelin MR, Mooser V, Melander O, Loos RJ, Elliott P, Abecasis GR, Caulfield M, Munroe PB.

Nat Genet. 2009 May 10. [Epub ahead of print]PMID: 19430483 [PubMed - as supplied by publisher]Related articles

21.

Melatonin receptors in pancreatic islets: good morning to a novel type 2 diabetes gene.

Mulder H, Nagorny CL, Lyssenko V, Groop L.

Diabetologia. 2009 Jul;52(7):1240-9. Epub 2009 Apr 18. Review.PMID: 19377888 [PubMed - indexed for MEDLINE]Related articles

22.

The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects.

Choquet H, Cavalcanti-Proença C, Lecoeur C, Dina C, Cauchi S, Vaxillaire M, Hadjadj S, Horber F, Potoczna N, Charpentier G, Ruiz J, Hercberg S, Maimaitiming S, Roussel R, Boenhnke M, Jackson AU, Patsch W, Krempler F, Voight BF, Altshuler D, Groop L, Thorleifsson G, Steinthorsdottir V, Stefansson K, Balkau B, Froguel P, Meyre D.

Hum Mol Genet. 2009 Jul 1;18(13):2495-501. Epub 2009 Apr 18.PMID: 19377085 [PubMed - indexed for MEDLINE]Related articles

23.

Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults.

Jonsson A, Renström F, Lyssenko V, Brito EC, Isomaa B, Berglund G, Nilsson PM, Groop L, Franks PW.

Diabetologia. 2009 Jul;52(7):1334-8. Epub 2009 Apr 17.PMID: 19373445 [PubMed - indexed for MEDLINE]Related articles

24.

Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults.

Brito EC, Lyssenko V, Renström F, Berglund G, Nilsson PM, Groop L, Franks PW.

Diabetes. 2009 Jun;58(6):1411-8. Epub 2009 Mar 26.PMID: 19324937 [PubMed - indexed for MEDLINE]Related articlesFree article

25.

Effect of pioglitazone versus insulin glargine on cardiac size, function, and measures of fluid retention in patients with type 2 diabetes.

Dorkhan M, Dencker M, Stagmo M, Groop L.

Cardiovasc Diabetol. 2009 Mar 20;8:15.PMID: 19298680 [PubMed - in process]Related articlesFree article

26.

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.

Pilgaard K, Jensen CB, Schou JH, Lyssenko V, Wegner L, Brøns C, Vilsbøll T, Hansen T, Madsbad S, Holst JJ, Vølund A, Poulsen P, Groop L, Pedersen O, Vaag AA.

Diabetologia. 2009 Jul;52(7):1298-307. Epub 2009 Mar 14.PMID: 19288077 [PubMed - indexed for MEDLINE]Related articles

27.

Genome-wide association study for type 2 diabetes: clinical applications.

Lyssenko V, Groop L.

Curr Opin Lipidol. 2009 Apr;20(2):87-91. Review.PMID: 19276887 [PubMed - indexed for MEDLINE]Related articles

28.

Genetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twins.

Rönn T, Poulsen P, Tuomi T, Isomaa B, Groop L, Vaag A, Ling C.

PLoS One. 2009;4(3):e4793. Epub 2009 Mar 10.PMID: 19274082 [PubMed - indexed for MEDLINE]Related articlesFree article

29.

Short-term exercise training does not stimulate skeletal muscle ATP synthesis in relatives of humans with type 2 diabetes.

Kacerovsky-Bielesz G, Chmelik M, Ling C, Pokan R, Szendroedi J, Farukuoye M, Kacerovsky M, Schmid AI, Gruber S, Wolzt M, Moser E, Pacini G, Smekal G, Groop L, Roden M.

Diabetes. 2009 Jun;58(6):1333-41. Epub 2009 Mar 5.PMID: 19265027 [PubMed - indexed for MEDLINE]Related articlesFree article

30.

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.

Osmark P, Hansson O, Jonsson A, Rönn T, Groop L, Renström E.

Diabetologia. 2009 May;52(5):850-4. Epub 2009 Feb 27.PMID: 19247628 [PubMed - indexed for MEDLINE]Related articles

31.

A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals.

Rönn T, Wen J, Yang Z, Lu B, Du Y, Groop L, Hu R, Ling C.

Diabetologia. 2009 May;52(5):830-3. Epub 2009 Feb 25.PMID: 19241057 [PubMed - indexed for MEDLINE]Related articles

32.

Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes.

Pulizzi N, Lyssenko V, Jonsson A, Osmond C, Laakso M, Kajantie E, Barker DJ, Groop LC, Eriksson JG.

Diabetologia. 2009 May;52(5):825-9. Epub 2009 Feb 19.PMID: 19225753 [PubMed - indexed for MEDLINE]Related articles

33.

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans.

Kotronen A, Johansson LE, Johansson LM, Roos C, Westerbacka J, Hamsten A, Bergholm R, Arkkila P, Arola J, Kiviluoto T, Fisher RM, Ehrenborg E, Orho-Melander M, Ridderstråle M, Groop L, Yki-Järvinen H.

Diabetologia. 2009 Jun;52(6):1056-60. Epub 2009 Feb 18.PMID: 19224197 [PubMed - indexed for MEDLINE]Related articles

34.

Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts.

Kotronen A, Yki-Järvinen H, Aminoff A, Bergholm R, Pietiläinen KH, Westerbacka J, Talmud PJ, Humphries SE, Hamsten A, Isomaa B, Groop L, Orho-Melander M, Ehrenborg E, Fisher RM.

Eur J Endocrinol. 2009 Apr;160(4):593-602. Epub 2009 Feb 10.PMID: 19208777 [PubMed - indexed for MEDLINE]Related articles

35.

Impaired mitochondrial function and insulin resistance of skeletal muscle in mitochondrial diabetes.

Szendroedi J, Schmid AI, Meyerspeer M, Cervin C, Kacerovsky M, Smekal G, Gräser-Lang S, Groop L, Roden M.

Diabetes Care. 2009 Apr;32(4):677-9. Epub 2009 Jan 8.PMID: 19131470 [PubMed - indexed for MEDLINE]Related articlesFree article

36.

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.

Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L, Randall JC, Roccasecca RM, Sanna S, Scheet P, Weedon MN, Wheeler E, Zhao JH, Jacobs LC, Prokopenko I, Soranzo N, Tanaka T, Timpson NJ, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chines P, Coin L, Collins FS, Connell JM, Cooper C, Smith GD, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada K, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta EG, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O'Rahilly S, Purmann C, Rees MG, Ridderstråle M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sims MA, Song K, Stephens J, Stevens S, Stringham HM, Tung YC, Valle TT, Van Duijn CM, Vimaleswaran KS, Vollenweider P, Waeber G, Wallace C, Watanabe RM, Waterworth DM, Watkins N; Wellcome Trust Case Control Consortium, Witteman JC, Zeggini E, Zhai G, Zillikens MC, Altshuler D, Caulfield MJ, Chanock SJ, Farooqi IS, Ferrucci L, Guralnik JM, Hattersley AT, Hu FB, Jarvelin MR, Laakso M, Mooser V, Ong KK, Ouwehand WH, Salomaa V, Samani NJ, Spector TD, Tuomi T, Tuomilehto J, Uda M, Uitterlinden AG, Wareham NJ, Deloukas P, Frayling TM, Groop LC, Hayes RB, Hunter DJ, Mohlke KL, Peltonen L, Schlessinger D, Strachan DP, Wichmann HE, McCarthy MI, Boehnke M, Barroso I, Abecasis GR, Hirschhorn JN; Genetic Investigation of ANthropometric Traits Consortium.

Nat Genet. 2009 Jan;41(1):25-34. Epub 2008 Dec 14.PMID: 19079261 [PubMed - indexed for MEDLINE]Related articlesFree article

37.

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion.

Lyssenko V, Nagorny CL, Erdos MR, Wierup N, Jonsson A, Spégel P, Bugliani M, Saxena R, Fex M, Pulizzi N, Isomaa B, Tuomi T, Nilsson P, Kuusisto J, Tuomilehto J, Boehnke M, Altshuler D, Sundler F, Eriksson JG, Jackson AU, Laakso M, Marchetti P, Watanabe RM, Mulder H, Groop L.

Nat Genet. 2009 Jan;41(1):82-8. Epub 2008 Dec 7.PMID: 19060908 [PubMed - indexed for MEDLINE]Related articles

38.

Variants in MTNR1B influence fasting glucose levels.

Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M, Lyssenko V, Chen WM, Ahmadi K, Beckmann JS, Bergman RN, Bochud M, Bonnycastle LL, Buchanan TA, Cao A, Cervino A, Coin L, Collins FS, Crisponi L, de Geus EJ, Dehghan A, Deloukas P, Doney AS, Elliott P, Freimer N, Gateva V, Herder C, Hofman A, Hughes TE, Hunt S, Illig T, Inouye M, Isomaa B, Johnson T, Kong A, Krestyaninova M, Kuusisto J, Laakso M, Lim N, Lindblad U, Lindgren CM, McCann OT, Mohlke KL, Morris AD, Naitza S, Orrù M, Palmer CN, Pouta A, Randall J, Rathmann W, Saramies J, Scheet P, Scott LJ, Scuteri A, Sharp S, Sijbrands E, Smit JH, Song K, Steinthorsdottir V, Stringham HM, Tuomi T, Tuomilehto J, Uitterlinden AG, Voight BF, Waterworth D, Wichmann HE, Willemsen G, Witteman JC, Yuan X, Zhao JH, Zeggini E, Schlessinger D, Sandhu M, Boomsma DI, Uda M, Spector TD, Penninx BW, Altshuler D, Vollenweider P, Jarvelin MR, Lakatta E, Waeber G, Fox CS, Peltonen L, Groop LC, Mooser V, Cupples LA, Thorsteinsdottir U, Boehnke M, Barroso I, Van Duijn C, Dupuis J, Watanabe RM, Stefansson K, McCarthy MI, Wareham NJ, Meigs JB, Abecasis GR.

Nat Genet. 2009 Jan;41(1):77-81. Epub 2008 Dec 7.PMID: 19060907 [PubMed - indexed for MEDLINE]Related articles

39.

Common variants at 30 loci contribute to polygenic dyslipidemia.

Kathiresan S, Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y, Tanaka T, Voight BF, Bonnycastle LL, Jackson AU, Crawford G, Surti A, Guiducci C, Burtt NP, Parish S, Clarke R, Zelenika D, Kubalanza KA, Morken MA, Scott LJ, Stringham HM, Galan P, Swift AJ, Kuusisto J, Bergman RN, Sundvall J, Laakso M, Ferrucci L, Scheet P, Sanna S, Uda M, Yang Q, Lunetta KL, Dupuis J, de Bakker PI, O'Donnell CJ, Chambers JC, Kooner JS, Hercberg S, Meneton P, Lakatta EG, Scuteri A, Schlessinger D, Tuomilehto J, Collins FS, Groop L, Altshuler D, Collins R, Lathrop GM, Melander O, Salomaa V, Peltonen L, Orho-Melander M, Ordovas JM, Boehnke M, Abecasis GR, Mohlke KL, Cupples LA.

Nat Genet. 2009 Jan;41(1):56-65. Epub 2008 Dec 7.PMID: 19060906 [PubMed - indexed for MEDLINE]Related articlesFree article

40.

Clinical risk factors, DNA variants, and the development of type 2 diabetes.

Lyssenko V, Jonsson A, Almgren P, Pulizzi N, Isomaa B, Tuomi T, Berglund G, Altshuler D, Nilsson P, Groop L.

N Engl J Med. 2008 Nov 20;359(21):2220-32.PMID: 19020324 [PubMed - indexed for MEDLINE]Related articlesFree article

41.

Fasting versus postload plasma glucose concentration and the risk for future type 2 diabetes: results from the Botnia Study.

Abdul-Ghani MA, Lyssenko V, Tuomi T, DeFronzo RA, Groop L.

Diabetes Care. 2009 Feb;32(2):281-6. Epub 2008 Nov 18.PMID: 19017778 [PubMed - indexed for MEDLINE]Related articlesFree article

42.

Genetic dissection of type 2 diabetes.

Ridderstråle M, Groop L.

Mol Cell Endocrinol. 2009 Jan 15;297(1-2):10-7. Epub 2008 Oct 19. Review.PMID: 19000735 [PubMed - indexed for MEDLINE]Related articles

43.

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies.

Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant SF, Farlow DN, Chandrupatla HR, Hansen M, Ajmal S, Papanicolaou GJ, Guo Y, Li M, Derohannessian S, de Bakker PI, Bailey SD, Montpetit A, Edmondson AC, Taylor K, Gai X, Wang SS, Fornage M, Shaikh T, Groop L, Boehnke M, Hall AS, Hattersley AT, Frackelton E, Patterson N, Chiang CW, Kim CE, Fabsitz RR, Ouwehand W, Price AL, Munroe P, Caulfield M, Drake T, Boerwinkle E, Reich D, Whitehead AS, Cappola TP, Samani NJ, Lusis AJ, Schadt E, Wilson JG, Koenig W, McCarthy MI, Kathiresan S, Gabriel SB, Hakonarson H, Anand SS, Reilly M, Engert JC, Nickerson DA, Rader DJ, Hirschhorn JN, Fitzgerald GA.

PLoS One. 2008;3(10):e3583. Epub 2008 Oct 31.PMID: 18974833 [PubMed - indexed for MEDLINE]Related articlesFree article

44.

Differences in effects of insulin glargine or pioglitazone added to oral anti-diabetic therapy in patients with type 2 diabetes: what to add--insulin glargine or pioglitazone?

Dorkhan M, Frid A, Groop L.

Diabetes Res Clin Pract. 2008 Dec;82(3):340-5. Epub 2008 Oct 15.PMID: 18926586 [PubMed - indexed for MEDLINE]Related articles

45.

The search for putative unifying genetic factors for components of the metabolic syndrome.

Sjögren M, Lyssenko V, Jonsson A, Berglund G, Nilsson P, Groop L, Orho-Melander M.

Diabetologia. 2008 Dec;51(12):2242-51. Epub 2008 Oct 14.PMID: 18853134 [PubMed - indexed for MEDLINE]Related articles

46.

Common variants in the TCF7L2 gene help to differentiate autoimmune from non-autoimmune diabetes in young (15-34 years) but not in middle-aged (40-59 years) diabetic patients.

Bakhtadze E, Cervin C, Lindholm E, Borg H, Nilsson P, Arnqvist HJ, Bolinder J, Eriksson JW, Gudbjörnsdottir S, Nyström L, Agardh CD, Landin-Olsson M, Sundkvist G, Groop LC.

Diabetologia. 2008 Dec;51(12):2224-32. Epub 2008 Oct 7.PMID: 18839133 [PubMed - indexed for MEDLINE]Related articles

47.

CCAAT/enhancer binding protein alpha (C/EBPalpha) in adipose tissue regulates genes in lipid and glucose metabolism and a genetic variation in C/EBPalpha is associated with serum levels of triglycerides.

Olofsson LE, Orho-Melander M, William-Olsson L, Sjöholm K, Sjöström L, Groop L, Carlsson B, Carlsson LM, Olsson B.

J Clin Endocrinol Metab. 2008 Dec;93(12):4880-6. Epub 2008 Sep 2.PMID: 18765514 [PubMed - indexed for MEDLINE]Related articles

48.

Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index.

Huth C, Illig T, Herder C, Gieger C, Grallert H, Vollmert C, Rathmann W, Hamid YH, Pedersen O, Hansen T, Thorand B, Meisinger C, Doring A, Klopp N, Gohlke H, Lieb W, Hengstenberg C, Lyssenko V, Groop L, Ireland H, Stephens JW, Wernstedt Asterholm I, Jansson JO, Boeing H, Mohlig M, Stringham HM, Boehnke M, Tuomilehto J, Fernandez-Real JM, Lopez-Bermejo A, Gallart L, Vendrell J, Humphries SE, Kronenberg F, Wichmann HE, Heid IM.

Ann Med. 2009;41(2):128-38.PMID: 18752089 [PubMed - indexed for MEDLINE]Related articles

49.

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

Yasuda K, Miyake K, Horikawa Y, Hara K, Osawa H, Furuta H, Hirota Y, Mori H, Jonsson A, Sato Y, Yamagata K, Hinokio Y, Wang HY, Tanahashi T, Nakamura N, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Takeda J, Maeda E, Shin HD, Cho YM, Park KS, Lee HK, Ng MC, Ma RC, So WY, Chan JC, Lyssenko V, Tuomi T, Nilsson P, Groop L, Kamatani N, Sekine A, Nakamura Y, Yamamoto K, Yoshida T, Tokunaga K, Itakura M, Makino H, Nanjo K, Kadowaki T, Kasuga M.

Nat Genet. 2008 Sep;40(9):1092-7.PMID: 18711367 [PubMed - indexed for MEDLINE]Related articles

50.

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations.

Orho-Melander M, Melander O, Guiducci C, Perez-Martinez P, Corella D, Roos C, Tewhey R, Rieder MJ, Hall J, Abecasis G, Tai ES, Welch C, Arnett DK, Lyssenko V, Lindholm E, Saxena R, de Bakker PI, Burtt N, Voight BF, Hirschhorn JN, Tucker KL, Hedner T, Tuomi T, Isomaa B, Eriksson KF, Taskinen MR, Wahlstrand B, Hughes TE, Parnell LD, Lai CQ, Berglund G, Peltonen L, Vartiainen E, Jousilahti P, Havulinna AS, Salomaa V, Nilsson P, Groop L, Altshuler D, Ordovas JM, Kathiresan S.

Diabetes. 2008 Nov;57(11):3112-21. Epub 2008 Aug 4.PMID: 18678614 [PubMed - indexed for MEDLINE]Related articlesFree article

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