PubMed

Clinical Heterogeneity in Monogenic Diabetes Caused by Mutations in the Glucokinase Gene (GCK-MODY).

Cuesta-Muñoz AL, Tuomi T, Cobo-Vuilleumier N, Koskela H, Odili S, Stride A, Buettger C, Otonkoski T, Froguel P, Grimsby J, Garcia-Gimeno M, Matschinsky FM.

Diabetes Care. 2009 Nov 10. [Epub ahead of print]PMID: 19903754 [PubMed - as supplied by publisher]Related articles

Extremes of clinical and enzymatic phenotypes in children with hyperinsulinism caused by glucokinase activating mutations.

Sayed S, Langdon DR, Odili S, Chen P, Buettger C, Schiffman AB, Suchi M, Taub R, Grimsby J, Matschinsky FM, Stanley CA.

Diabetes. 2009 Jun;58(6):1419-27. Epub 2009 Mar 31.PMID: 19336674 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucokinase activators for the potential treatment of type 2 diabetes.

Grimsby J, Berthel SJ, Sarabu R.

Curr Top Med Chem. 2008;8(17):1524-32. Review.PMID: 19075763 [PubMed - indexed for MEDLINE]Related articles

Lysyl oxidase oxidizes cell membrane proteins and enhances the chemotactic response of vascular smooth muscle cells.

Lucero HA, Ravid K, Grimsby JL, Rich CB, DiCamillo SJ, Mäki JM, Myllyharju J, Kagan HM.

J Biol Chem. 2008 Aug 29;283(35):24103-17. Epub 2008 Jun 27.PMID: 18586678 [PubMed - indexed for MEDLINE]Related articlesFree article

Sugar binding to recombinant wild-type and mutant glucokinase monitored by kinetic measurement and tryptophan fluorescence.

Zelent B, Odili S, Buettger C, Shiota C, Grimsby J, Taub R, Magnuson MA, Vanderkooi JM, Matschinsky FM.

Biochem J. 2008 Jul 15;413(2):269-80.PMID: 18370929 [PubMed - indexed for MEDLINE]Related articlesFree article

A glucose sensor role for glucokinase in anterior pituitary cells.

Zelent D, Golson ML, Koeberlein B, Quintens R, van Lommel L, Buettger C, Weik-Collins H, Taub R, Grimsby J, Schuit F, Kaestner KH, Matschinsky FM.

Diabetes. 2006 Jul;55(7):1923-9.PMID: 16804059 [PubMed - indexed for MEDLINE]Related articlesFree article

Small molecule glucokinase activators as glucose lowering agents: a new paradigm for diabetes therapy.

Guertin KR, Grimsby J.

Curr Med Chem. 2006;13(15):1839-43. Review.PMID: 16787225 [PubMed - indexed for MEDLINE]Related articles

From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation.

Sagen JV, Odili S, Bjørkhaug L, Zelent D, Buettger C, Kwagh J, Stanley C, Dahl-Jørgensen K, de Beaufort C, Bell GI, Han Y, Grimsby J, Taub R, Molven A, Søvik O, Njølstad PR, Matschinsky FM.

Diabetes. 2006 Jun;55(6):1713-22.PMID: 16731834 [PubMed - indexed for MEDLINE]Related articlesFree article

The network of glucokinase-expressing cells in glucose homeostasis and the potential of glucokinase activators for diabetes therapy.

Matschinsky FM, Magnuson MA, Zelent D, Jetton TL, Doliba N, Han Y, Taub R, Grimsby J.

Diabetes. 2006 Jan;55(1):1-12. Review.PMID: 16380470 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeting glucokinase activation for the treatment of type 2 diabetes--a status review.

Sarabu R, Grimsby J.

Curr Opin Drug Discov Devel. 2005 Sep;8(5):631-7. Review.PMID: 16159025 [PubMed - indexed for MEDLINE]Related articles

Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young.

Gloyn AL, Odili S, Zelent D, Buettger C, Castleden HA, Steele AM, Stride A, Shiota C, Magnuson MA, Lorini R, d'Annunzio G, Stanley CA, Kwagh J, van Schaftingen E, Veiga-da-Cunha M, Barbetti F, Dunten P, Han Y, Grimsby J, Taub R, Ellard S, Hattersley AT, Matschinsky FM.

J Biol Chem. 2005 Apr 8;280(14):14105-13. Epub 2005 Jan 25.PMID: 15677479 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucokinase and glucose homeostasis: proven concepts and new ideas.

Zelent D, Najafi H, Odili S, Buettger C, Weik-Collins H, Li C, Doliba N, Grimsby J, Matschinsky FM.

Biochem Soc Trans. 2005 Feb;33(Pt 1):306-10.PMID: 15667334 [PubMed - indexed for MEDLINE]Related articles

Novel mutations in the cellular retinaldehyde-binding protein gene (RLBP1) associated with retinitis punctata albescens: evidence of interfamilial genetic heterogeneity and fundus changes in heterozygotes.

Fishman GA, Roberts MF, Derlacki DJ, Grimsby JL, Yamamoto H, Sharon D, Nishiguchi KM, Dryja TP.

Arch Ophthalmol. 2004 Jan;122(1):70-5.PMID: 14718298 [PubMed - indexed for MEDLINE]Related articlesFree article

Rapid translocation of hepatic glucokinase in response to intraduodenal glucose infusion and changes in plasma glucose and insulin in conscious rats.

Chu CA, Fujimoto Y, Igawa K, Grimsby J, Grippo JF, Magnuson MA, Cherrington AD, Shiota M.

Am J Physiol Gastrointest Liver Physiol. 2004 Apr;286(4):G627-34. Epub 2003 Dec 4.PMID: 14656711 [PubMed - indexed for MEDLINE]Related articlesFree article

Allosteric activators of glucokinase: potential role in diabetes therapy.

Grimsby J, Sarabu R, Corbett WL, Haynes NE, Bizzarro FT, Coffey JW, Guertin KR, Hilliard DW, Kester RF, Mahaney PE, Marcus L, Qi L, Spence CL, Tengi J, Magnuson MA, Chu CA, Dvorozniak MT, Matschinsky FM, Grippo JF.

Science. 2003 Jul 18;301(5631):370-3.PMID: 12869762 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel mutations in the NRL gene and associated clinical findings in patients with dominant retinitis pigmentosa.

DeAngelis MM, Grimsby JL, Sandberg MA, Berson EL, Dryja TP.

Arch Ophthalmol. 2002 Mar;120(3):369-75.PMID: 11879142 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical features and mutations in patients with dominant retinitis pigmentosa-1 (RP1).

Berson EL, Grimsby JL, Adams SM, McGee TL, Sweklo E, Pierce EA, Sandberg MA, Dryja TP.

Invest Ophthalmol Vis Sci. 2001 Sep;42(10):2217-24.PMID: 11527933 [PubMed - indexed for MEDLINE]Related articlesFree article

Null RPGRIP1 alleles in patients with Leber congenital amaurosis.

Dryja TP, Adams SM, Grimsby JL, McGee TL, Hong DH, Li T, Andréasson S, Berson EL.

Am J Hum Genet. 2001 May;68(5):1295-8. Epub 2001 Mar 29.PMID: 11283794 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucokinase gene locus transgenic mice are resistant to the development of obesity-induced type 2 diabetes.

Shiota M, Postic C, Fujimoto Y, Jetton TL, Dixon K, Pan D, Grimsby J, Grippo JF, Magnuson MA, Cherrington AD.

Diabetes. 2001 Mar;50(3):622-9.PMID: 11246883 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of glucokinase regulatory protein-deficient mice.

Grimsby J, Coffey JW, Dvorozniak MT, Magram J, Li G, Matschinsky FM, Shiota C, Kaur S, Magnuson MA, Grippo JF.

J Biol Chem. 2000 Mar 17;275(11):7826-31.PMID: 10713097 [PubMed - indexed for MEDLINE]Related articlesFree article

Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase.

Shiota C, Coffey J, Grimsby J, Grippo JF, Magnuson MA.

J Biol Chem. 1999 Dec 24;274(52):37125-30.PMID: 10601273 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased stress response and beta-phenylethylamine in MAOB-deficient mice.

Grimsby J, Toth M, Chen K, Kumazawa T, Klaidman L, Adams JD, Karoum F, Gal J, Shih JC.

Nat Genet. 1997 Oct;17(2):206-10.PMID: 9326944 [PubMed - indexed for MEDLINE]Related articles

The metabolism of tyramine by monoamine oxidase A/B causes oxidative damage to mitochondrial DNA.

Hauptmann N, Grimsby J, Shih JC, Cadenas E.

Arch Biochem Biophys. 1996 Nov 15;335(2):295-304.PMID: 8914926 [PubMed - indexed for MEDLINE]Related articles

Identification of a region important for human monoamine oxidase B substrate and inhibitor selectivity.

Grimsby J, Zentner M, Shih JC.

Life Sci. 1996;58(9):777-87.PMID: 8632725 [PubMed - indexed for MEDLINE]Related articles

Epileptic seizures caused by inactivation of a novel gene, jerky, related to centromere binding protein-B in transgenic mice.

Toth M, Grimsby J, Buzsaki G, Donovan GP.

Nat Genet. 1995 Sep;11(1):71-5. Erratum in: Nat Genet 1996 Jan;12(1):110. PMID: 7550318 [PubMed - indexed for MEDLINE]Related articles

Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA.

Cases O, Seif I, Grimsby J, Gaspar P, Chen K, Pournin S, Müller U, Aguet M, Babinet C, Shih JC, et al.

Science. 1995 Jun 23;268(5218):1763-6.PMID: 7792602 [PubMed - indexed for MEDLINE]Related articles

Cloning of a novel monoamine oxidase cDNA from trout liver.

Chen K, Wu HF, Grimsby J, Shih JC.

Mol Pharmacol. 1994 Dec;46(6):1226-33.PMID: 7808446 [PubMed - indexed for MEDLINE]Related articles

Identification of human monoamine oxidase (MAO) A and B gene promoters.

Shih JC, Zhu QS, Grimsby J, Chen K.

J Neural Transm Suppl. 1994;41:27-33.PMID: 7931237 [PubMed - indexed for MEDLINE]Related articles

Structure and promoter organization of the human monoamine oxidase A and B genes.

Shih JC, Grimsby J, Chen K, Zhu QS.

J Psychiatry Neurosci. 1993 Jan;18(1):25-32.PMID: 8461277 [PubMed - indexed for MEDLINE]Related articlesFree article

Promoter organization and activity of human monoamine oxidase (MAO) A and B genes.

Zhu QS, Grimsby J, Chen K, Shih JC.

J Neurosci. 1992 Nov;12(11):4437-46.PMID: 1432104 [PubMed - indexed for MEDLINE]Related articlesFree article

The human 5-HT2 receptor is encoded by a multiple intron-exon gene.

Chen K, Yang W, Grimsby J, Shih JC.

Brain Res Mol Brain Res. 1992 Jun;14(1-2):20-6.PMID: 1323014 [PubMed - indexed for MEDLINE]Related articles

Dinucleotide repeat (TG)23 polymorphism in the MAOB gene.

Grimsby J, Chen K, Devor EJ, Cloninger CR, Shih JC.

Nucleic Acids Res. 1992 Feb 25;20(4):924. No abstract available. PMID: 1542591 [PubMed - indexed for MEDLINE]Related articlesFree article

Human monoamine oxidase A and B genes exhibit identical exon-intron organization.

Grimsby J, Chen K, Wang LJ, Lan NC, Shih JC.

Proc Natl Acad Sci U S A. 1991 May 1;88(9):3637-41.PMID: 2023912 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue distribution of human monoamine oxidase A and B mRNA.

Grimsby J, Lan NC, Neve R, Chen K, Shih JC.

J Neurochem. 1990 Oct;55(4):1166-9.PMID: 2398352 [PubMed - indexed for MEDLINE]Related articles

The expression of human MAO-A and B genes.

Shih JC, Grimsby J, Chen K.

J Neural Transm Suppl. 1990;32:41-7.PMID: 2089104 [PubMed - indexed for MEDLINE]Related articles

Human monoamine oxidase A and B genes map to Xp 11.23 and are deleted in a patient with Norrie disease.

Lan NC, Heinzmann C, Gal A, Klisak I, Orth U, Lai E, Grimsby J, Sparkes RS, Mohandas T, Shih JC.

Genomics. 1989 May;4(4):552-9.PMID: 2744764 [PubMed - indexed for MEDLINE]Related articles